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fluphenazine and Disease Models, Animal

fluphenazine has been researched along with Disease Models, Animal in 25 studies

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Reserpine treatment increased VCMs and decreased locomotor activity."5.39Effect of Hypericum perforatum on different models of movement disorders in rats. ( Athayde, ML; Boligon, AA; Busanello, A; Fachinetto, R; Leal, CQ; Reckziegel, P; Reis, EM; Röpke, J; Wagner, C, 2013)
"Acute dystonia can also be reliably induced in many primate species by neuroleptic treatment with comparable time course, symptomatology and pharmacological characteristics to those observed in man."2.37Acute dystonia induced by neuroleptic drugs. ( Jenner, P; Marsden, CD; Rupniak, NM, 1986)
"Wilson disease is a hereditary disorder caused by mutations of the ATP7B gene, which leads to intoxication with copper as a result of an unbalance of copper homeostasis."1.39[Copper intoxication decreases lifespan and induces neurologic alterations in Drosophila melanogaster]. ( Arcaya, JL; Salazar, U; Silva, EJ; Tejeda, CM; Urdaneta, K; Varela, K, 2013)
"Reserpine treatment increased VCMs and decreased locomotor activity."1.39Effect of Hypericum perforatum on different models of movement disorders in rats. ( Athayde, ML; Boligon, AA; Busanello, A; Fachinetto, R; Leal, CQ; Reckziegel, P; Reis, EM; Röpke, J; Wagner, C, 2013)
"Fluphenazine is a potent antipsychotic drug used to treat schizophrenia and other psychotic symptoms."1.35The antipsychotic drug, fluphenazine, effectively reverses mechanical allodynia in rat models of neuropathic pain. ( Cohen-Williams, M; Dong, XW; Hodgson, R; Jia, Y; Li, H; Lu, SX; Priestley, T; Zhou, X, 2008)
"The fluphenazine treatment produced VCMs in the majority of the treated rats (87% after 24 weeks)."1.34Diphenyl diselenide decreases the prevalence of vacuous chewing movements induced by fluphenazine in rats. ( Braga, AL; Calixto, JB; Fachinetto, R; Ferreira, J; Paixão, MW; Pereira, RP; Puntel, RL; Rocha, JB; Villarinho, JG; Wagner, C, 2007)
"Hyperprolactinemia is a known side-effect of fluphenazine, a broad spectrum, long-acting phenothiazine known to be D2 dopamine receptor antagonist."1.32Antifertility effects of fluphenazine in adult male rats. ( Aleem, M; Balasinor, N; Choudhary, J; D'Souza, S; Gill-Sharma, MK; Juneja, HS; Padwal, V; Parte, P; Sethi, G, 2003)
"The neuroleptic-induced catalepsy was reversed by the classical anti-parkinsonian agent L-DOPA and by agents that function through dopamine systems such as d- and methamphetamine and the direct D2 receptor agonist quinpirole."1.28Neuroleptic-induced catalepsy as a model of Parkinson's disease. I. Effect of dopaminergic agents. ( Close, SP; Elliott, PJ; Hayes, AG; Marriott, AS; Walsh, DM, 1990)
"In ongoing studies of chronic administration of neuroleptics to monkeys (Cebus apella) and rats, the regional distribution of glutamic acid decarboxylase (GAD) and brain levels of homovanillic acid were examined."1.27Experimental tardive dyskinesia. ( Gunne, LM; Häggström, JE, 1985)
"Haloperidol was given first in doses of 1."1.27Induction of tardive dyskinesia in Cebus apella and Macaca speciosa monkeys: a review. ( Domino, EF, 1985)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199010 (40.00)18.7374
1990's3 (12.00)18.2507
2000's5 (20.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Lu, Y1
Zhou, Z1
Mo, L1
Guo, Q1
Peng, X1
Hu, T1
Zhou, X2
Ren, B1
Xu, X1
Arcaya, JL1
Tejeda, CM1
Salazar, U1
Silva, EJ1
Urdaneta, K1
Varela, K1
Reis, EM1
Röpke, J1
Busanello, A1
Reckziegel, P1
Leal, CQ1
Wagner, C2
Boligon, AA1
Athayde, ML1
Fachinetto, R2
Li, J1
Pak, SC1
O'Reilly, LP1
Benson, JA1
Wang, Y1
Hidvegi, T1
Hale, P1
Dippold, C1
Ewing, M1
Silverman, GA1
Perlmutter, DH1
Wooters, TE1
Bardo, MT1
McCormick, SE1
Stoessl, AJ2
Gill-Sharma, MK1
Aleem, M1
Sethi, G1
Choudhary, J1
Padwal, V1
D'Souza, S1
Balasinor, N1
Parte, P1
Juneja, HS1
Villarinho, JG1
Pereira, RP1
Puntel, RL1
Paixão, MW1
Braga, AL1
Calixto, JB1
Rocha, JB1
Ferreira, J1
Dong, XW1
Jia, Y1
Lu, SX1
Cohen-Williams, M1
Hodgson, R1
Li, H1
Priestley, T1
Domino, EF3
Kovacic, B2
Bárány, S1
Häggström, JE2
Gunne, LM2
Sachdev, P1
Saharov, T1
Cathcart, S1
Van Kampen, JM1
Elliott, PJ2
Close, SP2
Walsh, DM2
Hayes, AG2
Marriott, AS2
See, RE2
Aravagiri, M1
Ellison, GD1
Weinstein, D1
Ellison, G1
Klawans, HL1
Carvey, P1
Tanner, CM1
Goetz, CG1
Rupniak, NM1
Jenner, P1
Marsden, CD1
Rosengarten, H1
Schweitzer, JW1
Egawa, M1
Friedhoff, AJ1

Reviews

1 review available for fluphenazine and Disease Models, Animal

ArticleYear
Acute dystonia induced by neuroleptic drugs.
    Psychopharmacology, 1986, Volume: 88, Issue:4

    Topics: Acute Disease; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Brain; Chlorpromazine; Disease M

1986

Other Studies

24 other studies available for fluphenazine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Fluphenazine antagonizes with fluconazole but synergizes with amphotericin B in the treatment of candidiasis.
    Applied microbiology and biotechnology, 2019, Volume: 103, Issue:16

    Topics: Amphotericin B; Animal Structures; Animals; Antifungal Agents; Antipsychotic Agents; Candida albican

2019
[Copper intoxication decreases lifespan and induces neurologic alterations in Drosophila melanogaster].
    Investigacion clinica, 2013, Volume: 54, Issue:1

    Topics: Age Factors; Animals; Copper Sulfate; Disease Models, Animal; Disease Progression; Dopamine Agents;

2013
Effect of Hypericum perforatum on different models of movement disorders in rats.
    Behavioural pharmacology, 2013, Volume: 24, Issue:7

    Topics: Animals; Disease Models, Animal; Fluphenazine; Hypericum; Male; Mastication; Motor Activity; Movemen

2013
Fluphenazine reduces proteotoxicity in C. elegans and mammalian models of alpha-1-antitrypsin deficiency.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Animals; Animals, Genetically Modified; Antipsy

2014
Methylphenidate and fluphenazine, but not amphetamine, differentially affect impulsive choice in spontaneously hypertensive, Wistar-Kyoto and Sprague-Dawley rats.
    Brain research, 2011, Jun-17, Volume: 1396

    Topics: Amphetamine; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulan

2011
Central administration of the neurotensin receptor antagonist SR48692 attenuates vacuous chewing movements in a rodent model of tardive dyskinesia.
    Neuroscience, 2003, Volume: 119, Issue:2

    Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug

2003
Antifertility effects of fluphenazine in adult male rats.
    Journal of endocrinological investigation, 2003, Volume: 26, Issue:4

    Topics: Animals; Disease Models, Animal; Dopamine Antagonists; Embryo Implantation; Female; Fertility; Fluph

2003
Diphenyl diselenide decreases the prevalence of vacuous chewing movements induced by fluphenazine in rats.
    Psychopharmacology, 2007, Volume: 194, Issue:3

    Topics: Animals; Antioxidants; Antipsychotic Agents; Behavior, Animal; Benzene Derivatives; Disease Models,

2007
The antipsychotic drug, fluphenazine, effectively reverses mechanical allodynia in rat models of neuropathic pain.
    Psychopharmacology, 2008, Volume: 195, Issue:4

    Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Fluphenazin

2008
Monkey models of tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Animals; Benztropine; Biperiden; Cebus; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Fl

1983
Application of a primate model for tardive dyskinesia.
    Acta pharmacologica et toxicologica, 1983, Volume: 52, Issue:2

    Topics: Animals; Cebus; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Fluphenazine; Histamine An

1983
A monkey model of tardive dyskinesia (TD): evidence that reversible TD may turn into irreversible TD.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:5

    Topics: Animals; Cebus; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Fluphenazine; Humans; Stre

1982
The preventative role of antioxidants (selegiline and vitamin E) in a rat model of tardive dyskinesia.
    Biological psychiatry, 1999, Dec-15, Volume: 46, Issue:12

    Topics: Animals; Antioxidants; Antipsychotic Agents; Delayed-Action Preparations; Disease Models, Animal; Dy

1999
Dopamine D(1A) receptor function in a rodent model of tardive dyskinesia.
    Neuroscience, 2000, Volume: 101, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Behavior,

2000
Neuroleptic-induced catalepsy as a model of Parkinson's disease. I. Effect of dopaminergic agents.
    Journal of neural transmission. Parkinson's disease and dementia section, 1990, Volume: 2, Issue:2

    Topics: Animals; Antipsychotic Agents; Catalepsy; Disease Models, Animal; Dopamine; Dose-Response Relationsh

1990
Neuroleptic-induced catalepsy as a model of Parkinson's disease. II. Effect of glutamate antagonists.
    Journal of neural transmission. Parkinson's disease and dementia section, 1990, Volume: 2, Issue:2

    Topics: Animals; Antipsychotic Agents; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Fluphenazine;

1990
Chronic neuroleptic treatment in rats produces persisting changes in GABAA and dopamine D-2, but not dopamine D-1 receptors.
    Life sciences, 1989, Volume: 44, Issue:3

    Topics: Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain; Disease Models, Animal; Dyskinesia,

1989
Delayed appearance of facial tics following chronic fluphenazine administration to guinea pigs.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4

    Topics: Animals; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Dr

1989
The pathophysiology of tardive dyskinesia.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:4 Pt 2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disea

1985
Experimental tardive dyskinesia.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:4 Pt 2

    Topics: Animals; Antipsychotic Agents; Brain; Cebus; Corpus Striatum; Disease Models, Animal; Drug Evaluatio

1985
Induction of tardive dyskinesia in Cebus apella and Macaca speciosa monkeys: a review.
    Psychopharmacology. Supplementum, 1985, Volume: 2

    Topics: Animals; Antipsychotic Agents; Benztropine; Cebus; Death, Sudden; Disease Models, Animal; Drug Thera

1985
Diminished D2 dopamine receptor function and the emergence of repetitive jaw movements.
    Advances in experimental medicine and biology, 1988, Volume: 235

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Disease Models, A

1988