Page last updated: 2024-10-27

fluphenazine and Brain Neoplasms

fluphenazine has been researched along with Brain Neoplasms in 4 studies

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
" screen phenothiazines for cytotoxic activity in glioma, neuroblastoma, and primary mouse brain tissue; and (2)."7.72Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors. ( Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E, 2004)
" screen phenothiazines for cytotoxic activity in glioma, neuroblastoma, and primary mouse brain tissue; and (2)."3.72Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors. ( Dayag, M; Gil-Ad, I; Levkovitz, Y; Shtaif, B; Weizman, A; Zeldich, E, 2004)
"The effects of chlorpromazine and related compounds upon soluble and particulate Ins(1,4,5)P3-5-phosphatase were investigated in rat GH3 pituitary and in human IMR-32 neuroblastoma cells."3.68Inhibition of inositol-1,4,5-trisphosphate-5-phosphatase by chlorpromazine and related compounds. ( Brännström, G; Fowler, CJ, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Xi, H1
Wu, M1
Ma, H1
Li, S1
Huang, Q1
Zhang, Y1
Xia, Y1
Berghauser Pont, LM1
Balvers, RK1
Kloezeman, JJ1
Nowicki, MO1
van den Bossche, W1
Kremer, A1
Wakimoto, H1
van den Hoogen, BG1
Leenstra, S1
Dirven, CM1
Chiocca, EA1
Lawler, SE1
Lamfers, ML1
Gil-Ad, I1
Shtaif, B1
Levkovitz, Y1
Dayag, M1
Zeldich, E1
Weizman, A1
Fowler, CJ1
Brännström, G1

Other Studies

4 other studies available for fluphenazine and Brain Neoplasms

ArticleYear
Repurposing fluphenazine to suppress melanoma brain, lung and bone metastasis by inducing G0/G1 cell cycle arrest and apoptosis and disrupting autophagic flux.
    Clinical & experimental metastasis, 2023, Volume: 40, Issue:2

    Topics: Apoptosis; Brain; Brain Neoplasms; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation;

2023
In vitro screening of clinical drugs identifies sensitizers of oncolytic viral therapy in glioblastoma stem-like cells.
    Gene therapy, 2015, Volume: 22, Issue:12

    Topics: Brain Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluphenazine; Glioblastoma; HCT116

2015
Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors.
    Journal of molecular neuroscience : MN, 2004, Volume: 22, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Calmodulin; Caspase 3; Caspases; Cell Di

2004
Inhibition of inositol-1,4,5-trisphosphate-5-phosphatase by chlorpromazine and related compounds.
    Methods and findings in experimental and clinical pharmacology, 1992, Volume: 14, Issue:8

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain Neoplasms; Cells, Cultured; Chlorpromazine; Fluphen

1992