fluoxetine has been researched along with Torsade de Pointes in 10 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine (Prozac) was more potent at blocking hERG 1a/1b than 1a channels, yielding a corresponding reduction in the safety margin." | 1.37 | hERG subunit composition determines differential drug sensitivity. ( Abi-Gerges, N; Holkham, H; Jones, EM; Pollard, CE; Robertson, GA; Valentin, JP, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wiśniowska, B | 1 |
| Mendyk, A | 1 |
| Fijorek, K | 1 |
| Glinka, A | 1 |
| Polak, S | 1 |
| Wei, A | 1 |
| Peng, J | 1 |
| Gu, Z | 1 |
| Li, J | 1 |
| Peters, S | 1 |
| Abi-Gerges, N | 1 |
| Holkham, H | 1 |
| Jones, EM | 1 |
| Pollard, CE | 1 |
| Valentin, JP | 1 |
| Robertson, GA | 1 |
| Curtis, LH | 1 |
| Østbye, T | 1 |
| Sendersky, V | 1 |
| Hutchison, S | 1 |
| Allen LaPointe, NM | 1 |
| Al-Khatib, SM | 1 |
| Usdin Yasuda, S | 1 |
| Dans, PE | 1 |
| Wright, A | 1 |
| Califf, RM | 1 |
| Woosley, RL | 1 |
| Schulman, KA | 1 |
| Wilting, I | 1 |
| Smals, OM | 1 |
| Holwerda, NJ | 1 |
| Meyboom, RH | 1 |
| de Bruin, ML | 1 |
| Egberts, TC | 1 |
| Buchanan Keller, K | 1 |
| Lemberg, L | 1 |
| Ciummo, PE | 1 |
| Katz, NL | 1 |
| Appleby, M | 1 |
| Mbewu, A | 1 |
| Clarke, B | 1 |
| Lherm, T | 1 |
| Lottin, F | 1 |
| Larbi, D | 1 |
| Bray, M | 1 |
| Legall, C | 1 |
| Caen, D | 1 |
1 review available for fluoxetine and Torsade de Pointes
| Article | Year |
|---|---|
QTc prolongation and torsades de pointes due to a coadministration of fluoxetine and amiodarone in a patient with implantable cardioverter-defibrillator: Case report and review of the literature.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Defibrillators, Implantable; Drug Inter | 2017 |
9 other studies available for fluoxetine and Torsade de Pointes
| Article | Year |
|---|---|
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computationa | 2012 |
QRS fragmentation in acquired long QT syndrome does not always predict torsades of pointes tachycardia: a case report.
Topics: Antidepressive Agents, Second-Generation; Diagnosis, Differential; Electrocardiography; Female; Fluo | 2014 |
hERG subunit composition determines differential drug sensitivity.
Topics: Action Potentials; Arrhythmias, Cardiac; Cell Line, Transformed; Drug Evaluation, Preclinical; Ether | 2011 |
Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients.
Topics: Adult; Aged; Amitriptyline; Anti-Bacterial Agents; Anti-Infective Agents; Antidepressive Agents, Sec | 2003 |
QTc prolongation and torsades de pointes in an elderly woman taking fluoxetine.
Topics: Aged, 80 and over; Female; Fluoxetine; Humans; Long QT Syndrome; Selective Serotonin Reuptake Inhibi | 2006 |
Torsade.
Topics: Anti-Bacterial Agents; Clarithromycin; Electrocardiography; Female; Fluoxetine; Humans; Middle Aged; | 2008 |
Interactions and drug-metabolizing enzymes.
Topics: Adolescent; Adult; Anti-Allergic Agents; Antidepressive Agents, Second-Generation; Antifungal Agents | 1995 |
Fluoxetine and ventricular torsade--is there a link?
Topics: Aged; Drug Monitoring; Electrocardiography; Female; Fluoxetine; Humans; Torsades de Pointes | 1995 |
[Torsade de pointes after poisoning with fluoxetine alone].
Topics: Adult; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Electrocardiograp | 2000 |