fluoxetine has been researched along with Syndrome in 32 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to determine the efficacy of non-hormonal therapy with citalopram vs fluoxetine for treating vasomotor syndrome (VMS) and urogenital syndrome of menopause (GSM) in Mexican women." | 9.51 | Citalopram improves vasomotor syndrome and urogenital syndrome of menopause in Mexican women: a randomized clinical trial. ( Álvarez-Pérez, MA; Bajonero-Domínguez, A; Cruz-Luna, M; Garmendia-Gallardo, C; González-Quiroz, JL; Hernández-Castañón, MY; Hernández-Hernández, VY; Loranca-Moreno, P; Ocampo-Godínez, JM; Rios-Espinosa, A; Sánchez-Tinoco, PM; Vergara Lope-Núñez, JA, 2022) |
| "Combination treatment with fluoxetine and moclobemide did not provide any indication of development of the "serotonin syndrome." | 9.08 | Pharmacokinetic and pharmacodynamic interactions between fluoxetine and moclobemide in the investigation of development of the "serotonin syndrome". ( Amrein, R; Dingemanse, J; Gieschke, R; Guentert, T; Wallnöfer, A, 1998) |
| "Dextromethorphan, a noncompetitive blocker of the N-methyl-D-aspartate (NMDA) type of glutamate receptor, at 45, 60 and 75 mg/kg, ip doses induced a behavioural syndrome characterised by reciprocal forepaw treading, lateral head-weaving, hind-limb abduction and flat body posture." | 7.73 | Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats. ( Balsara, JJ; Gaikwad, RV; Gaonkar, RK; Jadhav, JH; Jadhav, SA; Thorat, VM, 2005) |
| "A 48-year-old man presented to the emergency department with confusion, agitation, diaphoresis, and muscle rigidity after beginning treatment with fluoxetine, a serotonin reuptake inhibitor." | 7.69 | Fluoxetine and the serotonin syndrome. ( Ruiz, F, 1994) |
| "Discontinuation syndrome is associated with a rostral anterior cingulate Cho/Cre metabolite ratio decrease that may reflect dynamics of rostral anterior cingulate function." | 6.71 | Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. ( Cohen, BM; Frederick, Bd; Hennen, J; Henry, ME; Kaufman, MJ; Renshaw, PF; Schmidt, ME; Stoddard, EP; Villafuerte, RA, 2003) |
| "This study aimed to determine the efficacy of non-hormonal therapy with citalopram vs fluoxetine for treating vasomotor syndrome (VMS) and urogenital syndrome of menopause (GSM) in Mexican women." | 5.51 | Citalopram improves vasomotor syndrome and urogenital syndrome of menopause in Mexican women: a randomized clinical trial. ( Álvarez-Pérez, MA; Bajonero-Domínguez, A; Cruz-Luna, M; Garmendia-Gallardo, C; González-Quiroz, JL; Hernández-Castañón, MY; Hernández-Hernández, VY; Loranca-Moreno, P; Ocampo-Godínez, JM; Rios-Espinosa, A; Sánchez-Tinoco, PM; Vergara Lope-Núñez, JA, 2022) |
| "Serotonin syndrome is expected to occur more frequently with the increased use of specific serotonin reuptake inhibitors in the treatment of depression." | 5.29 | [Serotonergic syndrome--in combination therapy with lithium and fluoxetine]. ( Bjørndal, F; Karle, J, 1995) |
| "Combination treatment with fluoxetine and moclobemide did not provide any indication of development of the "serotonin syndrome." | 5.08 | Pharmacokinetic and pharmacodynamic interactions between fluoxetine and moclobemide in the investigation of development of the "serotonin syndrome". ( Amrein, R; Dingemanse, J; Gieschke, R; Guentert, T; Wallnöfer, A, 1998) |
| "Dissection of the styloid process via an extraoral approach is simple and reliable; dissection of the styloid process combined with antidepressants (fluoxetine) is preferred for treating Eagle's syndrome." | 3.77 | Eagle's syndrome treated with dissection of the styloid process via an extraoral approach combined with antidepressants. ( Chen, WL; Pan, JY; Peng, GG; Wu, JW, 2011) |
| "Dextromethorphan, a noncompetitive blocker of the N-methyl-D-aspartate (NMDA) type of glutamate receptor, at 45, 60 and 75 mg/kg, ip doses induced a behavioural syndrome characterised by reciprocal forepaw treading, lateral head-weaving, hind-limb abduction and flat body posture." | 3.73 | Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats. ( Balsara, JJ; Gaikwad, RV; Gaonkar, RK; Jadhav, JH; Jadhav, SA; Thorat, VM, 2005) |
| "A 48-year-old man presented to the emergency department with confusion, agitation, diaphoresis, and muscle rigidity after beginning treatment with fluoxetine, a serotonin reuptake inhibitor." | 3.69 | Fluoxetine and the serotonin syndrome. ( Ruiz, F, 1994) |
| "Discontinuation syndrome is associated with a rostral anterior cingulate Cho/Cre metabolite ratio decrease that may reflect dynamics of rostral anterior cingulate function." | 2.71 | Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. ( Cohen, BM; Frederick, Bd; Hennen, J; Henry, ME; Kaufman, MJ; Renshaw, PF; Schmidt, ME; Stoddard, EP; Villafuerte, RA, 2003) |
| "Fibromyalgia is a clinically well-defined chronic condition with a biopsychosocial aetiology." | 2.52 | Selective serotonin reuptake inhibitors for fibromyalgia syndrome. ( Cantrell, SE; Häuser, W; Nishishinya, MB; Urrútia, G; Walitt, B, 2015) |
| "Treatment with fluoxetine 60 mg/day for 12 weeks reduced obsessive symptoms by 60%, improving her quality of life." | 1.48 | The Stuck Song Syndrome: A Case of Musical Obsessions. ( Lizarazo Rodríguez, IL; Orjuela Rojas, JM, 2018) |
| "Dhat syndrome is a widely recognized clinical condition in the Indian subcontinent characterized by excessive preoccupation with semen loss as the main presenting complaint." | 1.35 | Depression in Dhat syndrome. ( Aggarwal, N; Dhikav, V; Gupta, S; Jadhavi, R; Singh, K, 2008) |
| "Serotonin syndrome is the result of the drug interaction that enhances serotonergic tone in the central nervous system." | 1.30 | Serotonin syndrome presenting with migrainelike stroke. ( Molaie, M, 1997) |
| "Serotonin syndrome is expected to occur more frequently with the increased use of specific serotonin reuptake inhibitors in the treatment of depression." | 1.29 | [Serotonergic syndrome--in combination therapy with lithium and fluoxetine]. ( Bjørndal, F; Karle, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.25) | 18.7374 |
| 1990's | 16 (50.00) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 6 (18.75) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Rios-Espinosa, A | 1 |
| Cruz-Luna, M | 1 |
| Garmendia-Gallardo, C | 1 |
| Hernández-Castañón, MY | 1 |
| Hernández-Hernández, VY | 1 |
| Sánchez-Tinoco, PM | 1 |
| Bajonero-Domínguez, A | 1 |
| Vergara Lope-Núñez, JA | 1 |
| Álvarez-Pérez, MA | 1 |
| González-Quiroz, JL | 1 |
| Loranca-Moreno, P | 1 |
| Ocampo-Godínez, JM | 1 |
| Orjuela Rojas, JM | 1 |
| Lizarazo Rodríguez, IL | 1 |
| Mao, M | 1 |
| Li, S | 1 |
| Zong, M | 1 |
| Qiu, L | 1 |
| Yang, J | 2 |
| Xia, J | 1 |
| Ji, M | 1 |
| Walitt, B | 1 |
| Urrútia, G | 1 |
| Nishishinya, MB | 1 |
| Cantrell, SE | 1 |
| Häuser, W | 1 |
| Chou, PH | 1 |
| Lin, BT | 1 |
| Lan, TH | 1 |
| Chan, CH | 1 |
| Peng, GG | 1 |
| Chen, WL | 1 |
| Wu, JW | 1 |
| Pan, JY | 1 |
| Padala, PR | 1 |
| Padala, KP | 1 |
| Monga, V | 1 |
| Ramirez, DA | 1 |
| Sullivan, DH | 1 |
| Kaufman, MJ | 1 |
| Henry, ME | 1 |
| Frederick, Bd | 1 |
| Hennen, J | 1 |
| Villafuerte, RA | 1 |
| Stoddard, EP | 1 |
| Schmidt, ME | 1 |
| Cohen, BM | 1 |
| Renshaw, PF | 1 |
| Gothelf, D | 1 |
| Presburger, G | 1 |
| Zohar, AH | 1 |
| Burg, M | 1 |
| Nahmani, A | 1 |
| Frydman, M | 1 |
| Shohat, M | 1 |
| Inbar, D | 1 |
| Aviram-Goldring, A | 1 |
| Yeshaya, J | 1 |
| Steinberg, T | 1 |
| Finkelstein, Y | 1 |
| Frisch, A | 1 |
| Weizman, A | 1 |
| Apter, A | 1 |
| Gaikwad, RV | 1 |
| Gaonkar, RK | 1 |
| Jadhav, SA | 1 |
| Thorat, VM | 1 |
| Jadhav, JH | 1 |
| Balsara, JJ | 1 |
| Lavenstein, B | 1 |
| Dhikav, V | 1 |
| Aggarwal, N | 1 |
| Gupta, S | 1 |
| Jadhavi, R | 1 |
| Singh, K | 1 |
| Power, BM | 1 |
| Pinder, M | 1 |
| Hackett, LP | 1 |
| Ilett, KF | 2 |
| Karle, J | 1 |
| Bjørndal, F | 1 |
| Ruiz, F | 1 |
| Dursun, SM | 1 |
| Mathew, VM | 1 |
| Reveley, MA | 1 |
| Nijhawan, PK | 1 |
| Katz, G | 1 |
| Winter, S | 1 |
| George, TP | 1 |
| Godleski, LS | 1 |
| Lejoyeux, M | 1 |
| Adès, J | 1 |
| Haddad, P | 1 |
| Ivanusa, Z | 1 |
| Hećimović, H | 1 |
| Demarin, V | 1 |
| Freeman, SA | 1 |
| Molaie, M | 1 |
| Schlienger, RG | 1 |
| Shear, NH | 1 |
| Dingemanse, J | 1 |
| Wallnöfer, A | 1 |
| Gieschke, R | 1 |
| Guentert, T | 1 |
| Amrein, R | 1 |
| Thompson, C | 1 |
| Carli, P | 1 |
| Gisserot, O | 1 |
| Marlier, S | 1 |
| Paris, JF | 1 |
| Rouleau, F | 1 |
| Asfar, P | 1 |
| Boulet, S | 1 |
| Dube, L | 1 |
| Dupuis, JM | 1 |
| Alquier, P | 1 |
| Victor, J | 1 |
| O'Malley, PG | 1 |
| Ooi, TK | 1 |
| Montgomery, SA | 1 |
| Gabriel, R | 1 |
| James, D | 1 |
| Hawley, C | 1 |
| Burkitt, P | 1 |
| Graham, PM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Citalopram Improves Vasomotor and Urogenital Syndromes in Mexican Patients With Post-menopause[NCT05346445] | 91 participants (Actual) | Interventional | 2021-01-20 | Completed | |||
| The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070] | 68 participants (Actual) | Interventional | 2007-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for fluoxetine and Syndrome
| Article | Year |
|---|---|
Selective serotonin reuptake inhibitors for fibromyalgia syndrome.
Topics: Amitriptyline; Citalopram; Fibromyalgia; Fluoxetine; Humans; Melatonin; Musculoskeletal Pain; Paroxe | 2015 |
Antidepressant discontinuation: a review of the literature.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanols; Depressive Disorder; Fluoxet | 1997 |
Newer antidepressants and the discontinuation syndrome.
Topics: Adverse Drug Reaction Reporting Systems; Cyclohexanols; Dizziness; Fluoxetine; Headache; Humans; Inc | 1997 |
Serotonin syndrome.
Topics: Fluoxetine; Humans; Monoamine Oxidase Inhibitors; Nervous System Diseases; Receptors, Serotonin; Ser | 1997 |
[Serotonin syndrome: a potentially severe side effect of selective serotonin reuptake inhibitors].
Topics: Antidepressive Agents, Second-Generation; Diagnosis, Differential; Fluoxetine; Humans; Prospective S | 1997 |
3 trials available for fluoxetine and Syndrome
| Article | Year |
|---|---|
Citalopram improves vasomotor syndrome and urogenital syndrome of menopause in Mexican women: a randomized clinical trial.
Topics: Citalopram; Female; Fluoxetine; Humans; Menopause; Postmenopause; Prospective Studies; Syndrome | 2022 |
Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study.
Topics: Adult; Brain Mapping; Choline; Depressive Disorder, Major; Female; Fluoxetine; Gyrus Cinguli; Humans | 2003 |
Pharmacokinetic and pharmacodynamic interactions between fluoxetine and moclobemide in the investigation of development of the "serotonin syndrome".
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antidepressive Agents; Benzamides; Blood Platelets; Drug Admi | 1998 |
24 other studies available for fluoxetine and Syndrome
| Article | Year |
|---|---|
The Stuck Song Syndrome: A Case of Musical Obsessions.
Topics: Adult; Chronic Disease; Female; Fluoxetine; Follow-Up Studies; Humans; Music; Obsessive-Compulsive D | 2018 |
Two-hit model of postintensive care syndrome induced by lipopolysaccharide challenge and subsequent chronic unpredictable stress in mice.
Topics: Animals; Anxiety; Chronic Disease; Cognition Disorders; Corticosterone; Critical Care; Critical Illn | 2019 |
Chronic Cotard's syndrome: recovery from 2 years' bed-ridden status.
Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chronic Disease; Delusions; Drug The | 2011 |
Eagle's syndrome treated with dissection of the styloid process via an extraoral approach combined with antidepressants.
Topics: Adult; Antidepressive Agents; Calcinosis; Depression; Female; Fluoxetine; Humans; Ligaments; Male; M | 2011 |
Reversal of SSRI-associated apathy syndrome by discontinuation of therapy.
Topics: Aged; Antidepressive Agents; Apathy; Citalopram; Depressive Disorder; Fluoxetine; Humans; Male; Midd | 2012 |
Obsessive-compulsive disorder in patients with velocardiofacial (22q11 deletion) syndrome.
Topics: Adolescent; Adult; Child; Chromosomes, Human, Pair 22; Craniofacial Abnormalities; Female; Fluoxetin | 2004 |
Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antitussive Agents; Behavior, Animal; Buspirone; Ce | 2005 |
Neonatal signs after in utero exposure to selective serotonin reuptake inhibitors.
Topics: Female; Fluoxetine; Humans; Infant Behavior; Infant, Newborn; Infant, Newborn, Diseases; Pregnancy; | 2005 |
Depression in Dhat syndrome.
Topics: Adult; Cultural Characteristics; Depression; Ejaculation; Erectile Dysfunction; Fluoxetine; Humans; | 2008 |
Fatal serotonin syndrome following a combined overdose of moclobemide, clomipramine and fluoxetine.
Topics: Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy | 1995 |
[Serotonergic syndrome--in combination therapy with lithium and fluoxetine].
Topics: Bipolar Disorder; Drug Interactions; Drug Therapy, Combination; Fluoxetine; Humans; Lithium Carbonat | 1995 |
Fluoxetine and the serotonin syndrome.
Topics: Akathisia, Drug-Induced; Confusion; Drug Therapy, Combination; Emergency Medicine; Fluoxetine; Human | 1994 |
Toxic serotonin syndrome after fluoxetine plus carbamazepine.
Topics: Carbamazepine; Drug Interactions; Female; Fluoxetine; Humans; Serotonin; Syndrome | 1993 |
Psychiatric illness and the serotonin syndrome: an emerging adverse drug effect leading to intensive care unit admission.
Topics: Alcohol Withdrawal Delirium; Buspirone; Clomipramine; Diagnosis, Differential; Drug Therapy, Combina | 1996 |
Possible serotonin syndrome with trazodone addition to fluoxetine.
Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Therapy, Combination; Epi | 1996 |
Clarification of the serotonin syndrome.
Topics: Antidepressive Agents, Second-Generation; Arousal; Fluoxetine; Headache; Humans; Serotonin; Sleep In | 1997 |
Serotonin syndrome presenting with migrainelike stroke.
Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Clomipramine; Confusi | 1997 |
Discontinuation of antidepressant therapy: emerging complications and their relevance.
Topics: Antidepressive Agents; Depressive Disorder; Fluoxetine; Humans; Paroxetine; Placebos; Randomized Con | 1998 |
[Exasperating hematomas].
Topics: Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Generation; Depression; Female; Fl | 1999 |
Transient ST segment elevation in right precordial leads induced by psychotropic drugs: relationship to the Brugada syndrome.
Topics: Adult; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; An | 2001 |
Treatment trials of unexplained symptom syndromes: time for larger and longer trials to address the complexities.
Topics: Female; Fibromyalgia; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Selective Serotonin | 2002 |
The serotonin syndrome.
Topics: Aged; Brain; Depression; Drug Interactions; Female; Fluoxetine; Humans; Monoamine Oxidase Inhibitors | 1991 |
The specificity of the zimelidine reaction.
Topics: Chemical and Drug Induced Liver Injury; Depressive Disorder; Drug Hypersensitivity; Fluoxetine; Huma | 1989 |
Danger of MAOI therapy after fluoxetine withdrawal.
Topics: Animals; Drug Interactions; Drug Therapy, Combination; Fluoxetine; Humans; Monoamine Oxidase Inhibit | 1988 |