Page last updated: 2024-10-27

fluoxetine and Syncope

fluoxetine has been researched along with Syncope in 12 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine appears to cause a low incidence of adverse cardiac effects."5.28Fluoxetine-induced bradycardia and syncope in two patients. ( Ellison, JM; Ely, E; Milofsky, JE, 1990)
"Fluoxetine was started six weeks prior to the syncopal episode in this patient, and is the medication most temporally associated with the event."1.28Case report of a syncopal episode associated with fluoxetine. ( Dreyling, CA; McAnally, LE; Threlkeld, KR, 1992)
"Fluoxetine appears to cause a low incidence of adverse cardiac effects."1.28Fluoxetine-induced bradycardia and syncope in two patients. ( Ellison, JM; Ely, E; Milofsky, JE, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (83.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Walsh, M1
Knilans, TK1
Anderson, JB1
Czosek, RJ1
Buchanan Keller, K1
Lemberg, L1
Kosinski, DJ1
Grubb, BP3
Elliott, L2
Dubois, B1
Wolfe, DA1
Samoil, D2
Temesy-Armos, P2
Hahn, H1
Kosinski, D1
Akpunonu, B1
Cherin, P1
Colvez, A1
Deville de Periere, G1
Sereni, D1
Raviña, T1
Suarez, ML1
Mendez-Castrillón, J1
Katz, A1
Kantor, A1
Battler, A1
McAnally, LE1
Threlkeld, KR1
Dreyling, CA1
Friedman, EH1
Feder, R1
Ellison, JM1
Milofsky, JE1
Ely, E1

Other Studies

12 other studies available for fluoxetine and Syncope

ArticleYear
Successful treatment of pallid breath-holding spells with fluoxetine.
    Pediatrics, 2012, Volume: 130, Issue:3

    Topics: Apnea; Electrocardiography; Female; Fluoxetine; Humans; Infant; Male; Pacemaker, Artificial; Selecti

2012
Torsade.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2008, Volume: 17, Issue:1

    Topics: Anti-Bacterial Agents; Clarithromycin; Electrocardiography; Female; Fluoxetine; Humans; Middle Aged;

2008
Treatment of malignant neurocardiogenic syncope with dual chamber cardiac pacing and fluoxetine hydrochloride.
    Pacing and clinical electrophysiology : PACE, 1995, Volume: 18, Issue:7

    Topics: Adult; Combined Modality Therapy; Female; Fluoxetine; Humans; Pacemaker, Artificial; Selective Serot

1995
Usefulness of fluoxetine hydrochloride for prevention of resistant upright tilt induced syncope.
    Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:3 Pt 1

    Topics: Adult; Bradycardia; Drug Tolerance; Female; Fluoxetine; Humans; Hypotension, Orthostatic; Male; Post

1993
The use of serotonin reuptake inhibitors for the treatment of recurrent syncope due to carotid sinus hypersensitivity unresponsive to dual chamber cardiac pacing.
    Pacing and clinical electrophysiology : PACE, 1994, Volume: 17, Issue:8

    Topics: 1-Naphthylamine; Aged; Cardiac Pacing, Artificial; Carotid Sinus; Fluoxetine; Follow-Up Studies; Hea

1994
Risk of syncope in the elderly and consumption of drugs: a case-control study.
    Journal of clinical epidemiology, 1997, Volume: 50, Issue:3

    Topics: Acepromazine; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antiparkinson Agent

1997
Fluoxetine-induced QTU interval prolongation, T wave alternans and syncope.
    International journal of cardiology, 1998, Volume: 65, Issue:3

    Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Fluoxetine; Humans; Middle Aged; Selective Seroto

1998
[Serotonin re-uptake inhibitors as primary therapy for carotid sinus hypersensitivity].
    Harefuah, 1998, Dec-01, Volume: 135, Issue:11

    Topics: Aged; Aged, 80 and over; Carotid Sinus; Fluoxetine; Humans; Male; Selective Serotonin Reuptake Inhib

1998
Case report of a syncopal episode associated with fluoxetine.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:9

    Topics: Adult; Electrocardiography; Electroencephalography; Fluoxetine; Humans; Male; Neurologic Examination

1992
The role of the right hemisphere in fluoxetine-induced bradycardia and syncope.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:3

    Topics: Bradycardia; Brain; Female; Fluoxetine; Functional Laterality; Humans; Sex Factors; Syncope

1991
Bradycardia and syncope induced by fluoxetine.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:3

    Topics: Adult; Blood Pressure; Bradycardia; Depressive Disorder; Dose-Response Relationship, Drug; Female; F

1991
Fluoxetine-induced bradycardia and syncope in two patients.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:9

    Topics: Adult; Bradycardia; Depressive Disorder; Female; Fluoxetine; Humans; Hypotension, Orthostatic; Synco

1990