fluoxetine has been researched along with Sleep Wake Disorders in 30 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study is to investigate the clinical therapeutic effects and safety of treating mild or moderate depression with somatic symptoms with electroacupuncture combined with Fluoxetine." | 9.14 | Efficacy evaluation for depression with somatic symptoms treated by electroacupuncture combined with Fluoxetine. ( Chen, LP; Duan, DM; Tu, Y; Wu, ZJ, 2009) |
| "Low-dose cotherapy of fluoxetine with clonazepam was safe and accelerated response over 21 days of treatment, decreasing anxiety and sleep disturbance as symptoms and partially suppressed them as SSRI side-effects; it also modestly reduced core symptoms of low mood and loss of interest." | 9.09 | Short-term cotherapy with clonazepam and fluoxetine: anxiety, sleep disturbance and core symptoms of depression. ( Glaudin, V; Londborg, PD; Painter, JR; Smith, WT, 2000) |
| "The authors' goal was to examine the hypnotic effects of slow-release melatonin during the initial 4 weeks of treatment with fluoxetine in 19 patients with major depressive disorder." | 9.08 | Melatonin for the treatment of sleep disturbances in major depressive disorder. ( Dolberg, OT; Grunhaus, L; Hirschmann, S, 1998) |
| "This study is to investigate the clinical therapeutic effects and safety of treating mild or moderate depression with somatic symptoms with electroacupuncture combined with Fluoxetine." | 5.14 | Efficacy evaluation for depression with somatic symptoms treated by electroacupuncture combined with Fluoxetine. ( Chen, LP; Duan, DM; Tu, Y; Wu, ZJ, 2009) |
| "Low-dose cotherapy of fluoxetine with clonazepam was safe and accelerated response over 21 days of treatment, decreasing anxiety and sleep disturbance as symptoms and partially suppressed them as SSRI side-effects; it also modestly reduced core symptoms of low mood and loss of interest." | 5.09 | Short-term cotherapy with clonazepam and fluoxetine: anxiety, sleep disturbance and core symptoms of depression. ( Glaudin, V; Londborg, PD; Painter, JR; Smith, WT, 2000) |
| "Forty-four outpatients with moderate to severe, nonpsychotic major depressive disorder (DSM-III-R) and insomnia were randomly assigned to receive nefazodone (Days 1-7, 200 mg/day; Days 8-56, 400 mg/day) or fluoxetine (Days 1-56, 20 mg/day)." | 5.08 | A comparison of nefazodone and fluoxetine on mood and on objective, subjective, and clinician-rated measures of sleep in depressed patients: a double-blind, 8-week clinical trial. ( Albala, BJ; Erman, MK; Gillin, JC; Rapaport, M; Winokur, A, 1997) |
| "Fluoxetine is associated with substantial objective and subjective sleep disturbance in adults with major depressive disorders." | 5.08 | The effect of fluoxetine on sleep EEG in childhood depression: a preliminary report. ( Armitage, R; Emslie, G; Rintelmann, J, 1997) |
| "The authors' goal was to examine the hypnotic effects of slow-release melatonin during the initial 4 weeks of treatment with fluoxetine in 19 patients with major depressive disorder." | 5.08 | Melatonin for the treatment of sleep disturbances in major depressive disorder. ( Dolberg, OT; Grunhaus, L; Hirschmann, S, 1998) |
| "One hundred and three patients of major depressive disorders were observed." | 2.79 | Effects of olanzapine-fluoxetine combination treatment of major depressive disorders on the quality of life during acute treatment period. ( Gu, S; Guo, J; Luo, H; Qu, W; Tang, Q, 2014) |
| "Amitriptyline was dosed as follows: 8 mg/day for 6 days, 8 mg twice a day for 6 days, 20 mg/day for 6 days, and 20 mg twice a day for 45 days." | 2.70 | Amitriptyline versus amitriptyline combined with fluoxetine in the preventative treatment of transformed migraine: a double-blind study. ( Alves, LA; Barbosa, JS; Krymchantowski, AV; Silva, MT, 2002) |
| "Fluoxetine is an efficacious, nonsedative antidepressant, but its selective efficacy on symptoms of insomnia has not been thoroughly explored." | 2.68 | The effects of fluoxetine on symptoms of insomnia in depressed patients. ( Faries, D; Satterlee, WG, 1995) |
| "Fluoxetine is an effective serotonin reuptake inhibitor antidepressant that can fail to alleviate either insomnia or major depression in a substantial minority of depressed patients." | 1.28 | Possible trazodone potentiation of fluoxetine: a case series. ( Cole, JO; Glass, L; Nierenberg, AA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (36.67) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 8 (26.67) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, Y | 1 |
| Raymer, BK | 1 |
| Boland, EM | 1 |
| Vittengl, JR | 1 |
| Clark, LA | 1 |
| Thase, ME | 2 |
| Jarrett, RB | 1 |
| Hamill Skoch, S | 1 |
| Mills, JA | 1 |
| Ramsey, L | 1 |
| Strawn, JR | 1 |
| Querido, AL | 1 |
| Hernandez-Leon, A | 1 |
| Fernández-Guasti, A | 1 |
| Martínez, A | 1 |
| Pellicer, F | 1 |
| González-Trujano, ME | 1 |
| Shahsavand-Ananloo, E | 1 |
| Berenji, F | 1 |
| Sadeghniiat, K | 1 |
| Alimadadi, A | 1 |
| Zahiroddin, AR | 1 |
| Tabatabaee, M | 1 |
| Abbasi-Asl, M | 1 |
| Ghaeli, P | 1 |
| Qu, W | 1 |
| Gu, S | 1 |
| Luo, H | 1 |
| Tang, Q | 1 |
| Guo, J | 1 |
| Vahia, IV | 1 |
| Sewell, DD | 1 |
| Vitiello, B | 1 |
| Silva, SG | 1 |
| Rohde, P | 1 |
| Kratochvil, CJ | 1 |
| Kennard, BD | 1 |
| Reinecke, MA | 1 |
| Mayes, TL | 1 |
| Posner, K | 1 |
| May, DE | 1 |
| March, JS | 1 |
| Duan, DM | 1 |
| Tu, Y | 1 |
| Chen, LP | 1 |
| Wu, ZJ | 1 |
| Feng, Y | 1 |
| Wang, XY | 1 |
| Li, SD | 1 |
| Zhang, Y | 1 |
| Wang, HM | 1 |
| Li, M | 1 |
| Cao, K | 1 |
| Ye, YF | 1 |
| Zhang, Z | 1 |
| Shamseddeen, W | 1 |
| Clarke, G | 1 |
| Keller, MB | 1 |
| Wagner, KD | 1 |
| Birmaher, B | 1 |
| Emslie, GJ | 1 |
| Ryan, N | 1 |
| Asarnow, JR | 1 |
| Porta, G | 1 |
| Brent, DA | 1 |
| Krymchantowski, AV | 1 |
| Silva, MT | 1 |
| Barbosa, JS | 1 |
| Alves, LA | 1 |
| Stein, MB | 1 |
| Kline, NA | 1 |
| Matloff, JL | 1 |
| Cirelli, C | 1 |
| Huber, R | 1 |
| Gopalakrishnan, A | 1 |
| Southard, TL | 1 |
| Tononi, G | 1 |
| Matsumoto, K | 1 |
| Guidotti, A | 1 |
| Costa, E | 1 |
| Nelson, JC | 1 |
| Portera, L | 1 |
| Leon, AC | 1 |
| Popa, D | 1 |
| Léna, C | 1 |
| Alexandre, C | 1 |
| Adrien, J | 1 |
| Satterlee, WG | 1 |
| Faries, D | 1 |
| Campbell, M | 1 |
| Cueva, JE | 1 |
| Armitage, R | 2 |
| Trivedi, M | 1 |
| Rush, AJ | 1 |
| Lester, BM | 1 |
| Cucca, J | 1 |
| Andreozzi, L | 1 |
| Flanagan, P | 1 |
| Oh, W | 1 |
| Sovner, R | 1 |
| Fox, CJ | 1 |
| Lowry, MJ | 1 |
| Lowry, MA | 1 |
| Gillin, JC | 1 |
| Rapaport, M | 1 |
| Erman, MK | 1 |
| Winokur, A | 1 |
| Albala, BJ | 1 |
| Emslie, G | 1 |
| Rintelmann, J | 1 |
| Dolberg, OT | 1 |
| Hirschmann, S | 1 |
| Grunhaus, L | 1 |
| Londborg, PD | 1 |
| Smith, WT | 1 |
| Glaudin, V | 1 |
| Painter, JR | 1 |
| Nierenberg, AA | 1 |
| Cole, JO | 1 |
| Glass, L | 1 |
| Schenck, CH | 1 |
| Mahowald, MW | 1 |
| Kim, SW | 1 |
| O'Connor, KA | 1 |
| Hurwitz, TD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of SSRI-Resistant Depression in Adolescents (TORDIA)[NCT00018902] | Phase 2/Phase 3 | 334 participants (Actual) | Interventional | 2001-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for fluoxetine and Sleep Wake Disorders
| Article | Year |
|---|---|
Sleep modulating agents.
Topics: Animals; Humans; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Wakefulness-Promoting Agen | 2019 |
Diving and antidepressants.
Topics: Antidepressive Agents; Blood Glucose; Decompression Sickness; Diving; Fluoxetine; Hemorrhage; Humans | 2017 |
[Stress and sleep/emotional disorder: possible involvement of neurosteroid allopregnanolone].
Topics: Affective Symptoms; Animals; Brain Chemistry; Female; Fluoxetine; Mice; Pregnanolone; Rats; Sleep Wa | 2005 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder | 1995 |
Depression, sleep, and antidepressants.
Topics: Adult; Antidepressive Agents; Bupropion; Circadian Rhythm; Comorbidity; Depressive Disorder; Electro | 1998 |
14 trials available for fluoxetine and Sleep Wake Disorders
| Article | Year |
|---|---|
Is sleep disturbance linked to short- and long-term outcomes following treatments for recurrent depression?
Topics: Adult; Antidepressive Agents; Cognitive Behavioral Therapy; Depressive Disorder, Major; Female; Fluo | 2020 |
Effects of olanzapine-fluoxetine combination treatment of major depressive disorders on the quality of life during acute treatment period.
Topics: Adult; Benzodiazepines; Depressive Disorder, Major; Drug Administration Schedule; Drug Combinations; | 2014 |
Suicidal events in the Treatment for Adolescents With Depression Study (TADS).
Topics: Adolescent; Child; Cognitive Behavioral Therapy; Depressive Disorder, Major; Diagnostic and Statisti | 2009 |
Efficacy evaluation for depression with somatic symptoms treated by electroacupuncture combined with Fluoxetine.
Topics: Adult; Antidepressive Agents, Second-Generation; Combined Modality Therapy; Depression; Dizziness; D | 2009 |
Clinical research of acupuncture on malignant tumor patients for improving depression and sleep quality.
Topics: Acupuncture Therapy; Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Depression; | 2011 |
Adjunctive sleep medications and depression outcome in the treatment of serotonin-selective reuptake inhibitor resistant depression in adolescents study.
Topics: Adolescent; Cognitive Behavioral Therapy; Combined Modality Therapy; Cyclohexanols; Cytochrome P-450 | 2012 |
Amitriptyline versus amitriptyline combined with fluoxetine in the preventative treatment of transformed migraine: a double-blind study.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Constipation; Double-Blind Method; Drug Therapy, | 2002 |
Adjunctive olanzapine for SSRI-resistant combat-related PTSD: a double-blind, placebo-controlled study.
Topics: Antipsychotic Agents; Benzodiazepines; Combat Disorders; Depressive Disorder; Double-Blind Method; D | 2002 |
Residual symptoms in depressed patients after treatment with fluoxetine or reboxetine.
Topics: Adrenergic Uptake Inhibitors; Adult; Anxiety Disorders; Depression; Depressive Disorder; Double-Blin | 2005 |
The effects of fluoxetine on symptoms of insomnia in depressed patients.
Topics: Adolescent; Adult; Depression; Depressive Disorder; Female; Fluoxetine; Humans; Male; Middle Aged; P | 1995 |
A comparison of nefazodone and fluoxetine on mood and on objective, subjective, and clinician-rated measures of sleep in depressed patients: a double-blind, 8-week clinical trial.
Topics: Adult; Affect; Ambulatory Care; Antidepressive Agents, Second-Generation; Depressive Disorder; Doubl | 1997 |
The effect of fluoxetine on sleep EEG in childhood depression: a preliminary report.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Arousal; Autoanalysis; Child; Depressive Disor | 1997 |
Melatonin for the treatment of sleep disturbances in major depressive disorder.
Topics: Adult; Aged; Ambulatory Care; Analysis of Variance; Delayed-Action Preparations; Depressive Disorder | 1998 |
Short-term cotherapy with clonazepam and fluoxetine: anxiety, sleep disturbance and core symptoms of depression.
Topics: Adult; Aged; Anxiety; Clonazepam; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug | 2000 |
11 other studies available for fluoxetine and Sleep Wake Disorders
| Article | Year |
|---|---|
Topics: Adolescent; Anxiety Disorders; Fluoxetine; Humans; Meta-Analysis as Topic; Selective Serotonin Reupt | 2021 |
Sleep architecture is altered in the reserpine-induced fibromyalgia model in ovariectomized rats.
Topics: Animals; Disease Models, Animal; Female; Fibromyalgia; Fluoxetine; Hyperalgesia; Ovariectomy; Pain; | 2019 |
Comparing effects of citalopram with fluoxetine on sleep quality in patients with major depressive disorder.
Topics: Adolescent; Adult; Citalopram; Depressive Disorder, Major; Diagnostic and Statistical Manual of Ment | 2013 |
Late-Life Depression: A Role for Accelerometer Technology in Diagnosis and Management.
Topics: Actigraphy; Aged, 80 and over; Antidepressive Agents; Aripiprazole; Depression; Exercise; Fluoxetine | 2016 |
Locus ceruleus control of slow-wave homeostasis.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzylamines; Brain; Brain Chemistry; Dopamine; Dru | 2005 |
Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Animals, Newborn; Antidepress | 2008 |
Fluoxetine and oculomotor activity during sleep in depressed patients.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Depression; Electroencephalography; Electromyography; Elec | 1995 |
Possible association between fluoxetine hydrochloride and colic in an infant.
Topics: Adult; Breast Feeding; Colic; Crying; Feeding Behavior; Female; Fluoxetine; Humans; Infant, Newborn; | 1993 |
Fluoxetine treatment of depression and associated self-injury in two adults with mental retardation.
Topics: Adult; Depressive Disorder; Female; Fluoxetine; Humans; Institutionalization; Intellectual Disabilit | 1993 |
Possible trazodone potentiation of fluoxetine: a case series.
Topics: Adult; Depressive Disorder; Drug Synergism; Drug Therapy, Combination; Female; Fluoxetine; Humans; M | 1992 |
Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder.
Topics: Adult; Antidepressive Agents, Tricyclic; Arousal; Brain; Depressive Disorder; Dreams; Electroencepha | 1992 |