Page last updated: 2024-10-27

fluoxetine and Schizophrenia

fluoxetine has been researched along with Schizophrenia in 71 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"Significant weight gain is a side effect associated with olanzapine treatment in some patients."9.10Treatment of weight gain with fluoxetine in olanzapine-treated schizophrenic outpatients. ( Bogenschutz, M; Bustillo, JR; Hammond, R; Keith, S; Lauriello, J; Parker, K; Rowland, L, 2003)
"First-episode hospitalized schizophrenia patients (N=30) were randomly assigned in an 8-week double-blind study of olanzapine, 10 mg/day, coadministered with either fluoxetine, 20 mg/day (N=15), or placebo (N=15)."9.10Olanzapine-induced weight gain in patients with first-episode schizophrenia: a double-blind, placebo-controlled study of fluoxetine addition. ( Fuchs, C; Gil-Ad, I; Maayan, R; Pashinian, A; Poyurovsky, M; Schneidman, M; Weizman, A, 2002)
"The effect of fluoxetine on the steady-state plasma concentrations of risperidone and its active metabolite 9-hydroxyrisperidone (9-OH-risperidone) was evaluated in 10 patients with schizophrenia or schizoaffective disorder."7.71Inhibition of risperidone metabolism by fluoxetine in patients with schizophrenia: a clinically relevant pharmacokinetic drug interaction. ( Ancione, M; Avenoso, A; Gatti, G; Madia, A; Perucca, E; Scordo, MG; Spina, E, 2002)
"Case 2 was a female with schizoaffective disorder without a history of NMS."6.52Atypical neuroleptic malignant syndrome in patients treated with aripiprazole and clozapine: a case-series study and short review. ( Chang, CH; Chang, YC; Chen, YW; Cheng, YS; Chung, W; Tseng, PT; Wang, HY; Wu, CK, 2015)
"There is low-certainty evidence to suggest that metformin may be effective in preventing weight gain."5.22Pharmacological interventions for prevention of weight gain in people with schizophrenia. ( Agarwal, SM; Ahsan, ZA; Cohn, T; Duncan, MJ; Faulkner, GEJ; Hahn, M; Lockwood, JT; Remington, G; Stogios, N; Takeuchi, H; Taylor, VH, 2022)
"Significant weight gain is a side effect associated with olanzapine treatment in some patients."5.10Treatment of weight gain with fluoxetine in olanzapine-treated schizophrenic outpatients. ( Bogenschutz, M; Bustillo, JR; Hammond, R; Keith, S; Lauriello, J; Parker, K; Rowland, L, 2003)
"The effects of fluoxetine and imipramine on the pharmacokinetics and nonpsychiatric side effect profile of quetiapine fumarate were investigated in 26 patients with schizophrenia, schizoaffective disorder, or bipolar disorder in a multicenter, two-period, multiple-dose, open-label, randomized trial."5.10Effect of fluoxetine and imipramine on the pharmacokinetics and tolerability of the antipsychotic quetiapine. ( Alva, G; Arvanitis, LA; Carreon, D; Kalali, A; Potkin, SG; Thyrum, PT; Yeh, C, 2002)
"First-episode hospitalized schizophrenia patients (N=30) were randomly assigned in an 8-week double-blind study of olanzapine, 10 mg/day, coadministered with either fluoxetine, 20 mg/day (N=15), or placebo (N=15)."5.10Olanzapine-induced weight gain in patients with first-episode schizophrenia: a double-blind, placebo-controlled study of fluoxetine addition. ( Fuchs, C; Gil-Ad, I; Maayan, R; Pashinian, A; Poyurovsky, M; Schneidman, M; Weizman, A, 2002)
"Mean ratings of positive and negative symptoms and depression significantly improved in nine treatment-resistant schizophrenic patients who completed a 6-week open trial of fluoxetine added to their neuroleptics."5.06Trial of fluoxetine added to neuroleptics for treatment-resistant schizophrenic patients. ( Brotman, AW; Goff, DC; McCormick, S; Waites, M, 1990)
" The three case studies are (1) bupropion versus nicotine replacement therapy for smoking cessation, (2) risperidone versus haloperidol for schizophrenia, and (3) fluoxetine versus imipramine for depressive disorders."4.84Adjusted indirect comparison may be less biased than direct comparison for evaluating new pharmaceutical interventions. ( Harvey, I; Lilford, R; Song, F, 2008)
" Subsequently, density of [(3)H]LY341495 binding was measured in BA24(anterior cingulate cortex), BA17(visual cortex) and BA46(dorsolateral prefrontal cortex) from subjects with MDD, Bipolar Disorder(BPD), Schizophrenia(SCZ), and controls, as well as rats treated with imipramine (20mg/kg), fluoxetine (10mg/kg), or vehicle."3.83Lower [3H]LY341495 binding to mGlu2/3 receptors in the anterior cingulate of subjects with major depressive disorder but not bipolar disorder or schizophrenia. ( Dean, B; Gibbons, A; Hopper, S; McOmish, CE; Pavey, G; Scarr, E; Udawela, M, 2016)
"Since the prefrontal cortex (PFC) is thought to play an important role in depression and schizophrenia, we studied the effects of fluoxetine and olanzapine on PFC neurons in rats using extracellular, in vivo recordings."3.72Electrophysiological effects of acute and chronic olanzapine and fluoxetine in the rat prefrontal cortex. ( Gronier, BS; Rasmussen, K, 2003)
"The effect of fluoxetine on the steady-state plasma concentrations of risperidone and its active metabolite 9-hydroxyrisperidone (9-OH-risperidone) was evaluated in 10 patients with schizophrenia or schizoaffective disorder."3.71Inhibition of risperidone metabolism by fluoxetine in patients with schizophrenia: a clinically relevant pharmacokinetic drug interaction. ( Ancione, M; Avenoso, A; Gatti, G; Madia, A; Perucca, E; Scordo, MG; Spina, E, 2002)
"A 26-year-old man with schizophrenia, disorganised type, and depression, developed severe tardive dyskinesia during treatment with risperidone and fluoxetine."3.70[Severe tardive dyskinesia during treatment with risperidone and fluoxetine]. ( Dubbelman, YD; Heeringa, M; Thung, FH, 1998)
"As fluoxetine is a potent inhibitor of cytochrome P450 (CYP) 2D6, these results also provide indirect evidence for an involvement of CYP2D6 in the metabolism of haloperidol."2.68Interaction between fluoxetine and haloperidol: pharmacokinetic and clinical implications. ( Avenoso, A; Campo, G; Caputi, AP; Facciolă, G; Ferlito, M; Perucca, E; Spinà, E; Zuccaro, P, 1997)
"Fluoxetine treatment did not influence positive schizophrenic symptoms, while it induced a slight, but statistically significant, decrease (p < 0."2.67Adjunctive fluoxetine in the treatment of negative symptoms in chronic schizophrenic patients. ( Ancione, M; Caputi, AP; De Domenico, P; Di Rosa, AE; Gitto, C; Longobardo, N; Ruello, C; Spina, E, 1994)
"With valproic acid, there was a minor increase in total clozapine metabolites, which was even less with dose correction."2.67Serum concentrations of clozapine and its major metabolites: effects of cotreatment with fluoxetine or valproate. ( Baldessarini, RJ; Centorrino, F; Flood, JG; Frankenburg, FR; Kando, J; Puopolo, PR; Volpicelli, SA, 1994)
"Case 2 was a female with schizoaffective disorder without a history of NMS."2.52Atypical neuroleptic malignant syndrome in patients treated with aripiprazole and clozapine: a case-series study and short review. ( Chang, CH; Chang, YC; Chen, YW; Cheng, YS; Chung, W; Tseng, PT; Wang, HY; Wu, CK, 2015)
"Fluoxetine (20 mg/day) was added for 7-10 days to stable doses of haloperidol given to eight psychotic patients."1.28Elevation of plasma concentrations of haloperidol after the addition of fluoxetine. ( Baldessarini, RJ; Brotman, AW; Goff, DC; Midha, KK; Waites, M, 1991)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.41)18.7374
1990's41 (57.75)18.2507
2000's18 (25.35)29.6817
2010's10 (14.08)24.3611
2020's1 (1.41)2.80

Authors

AuthorsStudies
Agarwal, SM1
Stogios, N1
Ahsan, ZA1
Lockwood, JT1
Duncan, MJ1
Takeuchi, H1
Cohn, T1
Taylor, VH1
Remington, G1
Faulkner, GEJ1
Hahn, M1
Tseng, PT1
Chang, YC1
Chang, CH1
Wang, HY1
Cheng, YS1
Wu, CK1
Chen, YW1
Chung, W1
Jayarajan, RN1
Shere, S1
Sutar, R1
Karmani, S1
Reddi, VS1
Kesavan, M1
Viswanath, B1
Jain, S1
McOmish, CE1
Pavey, G1
Gibbons, A1
Hopper, S1
Udawela, M1
Scarr, E1
Dean, B1
Figueiredo, T1
Segenreich, D1
Mattos, P1
Mowla, A1
Dastgheib, SA1
Ebrahimi, AA1
Pani, A1
Yang, FW1
Liang, CS1
Korkmaz, S1
Işik, U1
Korkmaz, H1
Takashima, N1
Odaka, YS1
Sakoori, K1
Akagi, T1
Hashikawa, T1
Morimura, N1
Yamada, K1
Aruga, J1
Richtand, NM1
Ahlbrand, R1
Horn, P1
Tambyraja, R1
Grainger, M1
Bronson, SL1
McNamara, RK1
Raghunath, A1
Andrade, C1
Spina, E4
Avenoso, A3
Scordo, MG1
Ancione, M2
Madia, A1
Gatti, G1
Perucca, E3
Safranko, I1
Bustillo, JR1
Lauriello, J1
Parker, K1
Hammond, R1
Rowland, L1
Bogenschutz, M1
Keith, S1
Gronier, BS1
Rasmussen, K1
Shim, JC1
Kelly, DL1
Kim, YH1
Yoon, YR1
Park, JH1
Shin, JG1
Conley, RR1
Kordon, A1
Broocks, A1
Hohagen, F1
Levy, E1
Margolese, HC1
Sultan, S1
Chouinard, G1
Sayeed Khan, MN1
Arshad, N1
Ullah, N1
Silver, H1
Mackin, P1
Young, AH1
Theleritis, CG1
Papadimitriou, GN1
Papageorgiou, CC1
Dikeos, DG1
Masdrakis, V1
Kostoulas, C1
Psarros, C1
Soldatos, CR1
Ozturk, S1
Ozsenel, EB1
Kazancioglu, R1
Turkmen, A1
Song, F1
Harvey, I1
Lilford, R1
Enna, SJ1
Campbell, M1
Cueva, JE1
Rothschild, AJ1
Goff, DC3
Midha, KK2
Sarid-Segal, O1
Hubbard, JW1
Amico, E1
Bellino, S1
Barzega, G1
Bogetto, F1
Maina, G1
Ravizza, L1
D'Souza, DC1
Bennett, A1
Abi-Dargham, A1
Krystal, JH1
De Domenico, P1
Ruello, C1
Longobardo, N1
Gitto, C1
Di Rosa, AE1
Caputi, AP3
Kulik, FA1
Wilbur, R1
Bacher, NM2
Sanzone, MM1
Kaup, B1
Caroli, F2
Baldacci-Epinette, C1
Ribeyre, P1
Eales, MJ1
Layeni, AO1
Eggert, AE1
Crismon, ML1
Dorson, PG1
Sewell, DD1
Lopez, WM1
Paulsen, J1
Gilbert, P1
Hwang, MY2
Martin, AM1
Lindenmayer, JP2
Stein, D2
Hollander, E2
Centorrino, F2
Baldessarini, RJ3
Kando, J2
Frankenburg, FR2
Volpicelli, SA2
Puopolo, PR1
Flood, JG2
Tejera, CA1
Mayerhoff, DJ1
Safferman, AZ1
Ramos-Lorenzi, JR1
Simeon, D1
Ninan, PT1
Shelton, S1
Patel, B1
Tandon, R1
Daniel, DG1
Smith, K1
Hyde, T1
Egan, M1
Maes, M1
De Meester, I1
Scharpe, S1
Desnyder, R1
Ranjan, R1
Meltzer, HY1
Buchanan, RW2
Kirkpatrick, B2
Bryant, N1
Ball, P1
Breier, A1
Campo, G1
Facciolă, G2
Ferlito, M1
Zuccaro, P1
Purdon, SE1
Snaterse, M1
Fabrazzo, M1
Monteleone, P1
Maj, M1
Dubbelman, YD1
Thung, FH1
Heeringa, M1
Lane, HY2
Liu, CC1
Chang, WH2
Mahendran, R1
Mottard, JP1
de la Sablonnière, JF1
Aymard, N1
Viala, A1
Baldacci, C1
Smagghe, PO1
Vacheron, MN1
Lu, ML1
Arango, C1
Lund, BC1
Perry, PJ1
Miller, DD1
Potkin, SG1
Thyrum, PT1
Alva, G1
Carreon, D1
Yeh, C1
Kalali, A1
Arvanitis, LA1
Poyurovsky, M1
Pashinian, A1
Gil-Ad, I1
Maayan, R1
Schneidman, M1
Fuchs, C1
Weizman, A1
Cassady, SL1
Thaker, GK1
Brewerton, TD1
Shannon, M1
Baker, RW1
Ruskin, P1
Brotman, AW2
Waites, M2
McCormick, S1
Goldman, MB2
Janecek, HM2
Kim, SW1
Dysken, MW1
Vakharia, M1
Kanofsky, D1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparison of Bupropion SR and Placebo for Smoking Cessation[NCT00176449]Phase 452 participants (Actual)Interventional2001-04-30Completed
Alterations in mRNA and Protein Expression in Human Peripheral Mononuclear Blood Cells (PMC) of Schizophrenia Patients Treated With Fluvoxamine Augmentation of Antipsychotics: Relationship to Clinical Symptoms and Cognitive Function[NCT00645580]15 participants (Anticipated)Interventional2008-04-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for fluoxetine and Schizophrenia

ArticleYear
Pharmacological interventions for prevention of weight gain in people with schizophrenia.
    The Cochrane database of systematic reviews, 2022, 10-03, Volume: 10

    Topics: Antipsychotic Agents; Betahistine; Famotidine; Fluoxetine; Humans; Melatonin; Metformin; Nausea; Niz

2022
Atypical neuroleptic malignant syndrome in patients treated with aripiprazole and clozapine: a case-series study and short review.
    International journal of psychiatry in medicine, 2015, Volume: 49, Issue:1

    Topics: Adult; Aripiprazole; Clozapine; Creatine Kinase; Dose-Response Relationship, Drug; Drug Substitution

2015
[Obsessive-compulsive disorders in general practice. How the obsessive-compulsive neurotic is revealed by skin and hair].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Age

2003
Selective serotonin re-uptake inhibitor augmentation in the treatment of negative symptoms of schizophrenia.
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:10

    Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chemotherapy, Adjuvant; Fluoxetine;

2004
Adjusted indirect comparison may be less biased than direct comparison for evaluating new pharmaceutical interventions.
    Journal of clinical epidemiology, 2008, Volume: 61, Issue:5

    Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bias; Bupropion; Data Interpretation

2008
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:10

    Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder

1995
[Antidepressant treatment of schizophrenic patients].
    L'Encephale, 1993, Volume: 19 Spec No 2

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Depressive Disorder; Drug Therapy, Combination;

1993

Trials

13 trials available for fluoxetine and Schizophrenia

ArticleYear
Treatment of weight gain with fluoxetine in olanzapine-treated schizophrenic outpatients.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Benzodiazepines; Double-Blind Method; Female; Fluoxetine; H

2003
A placebo-controlled trial of fluoxetine added to neuroleptic in patients with schizophrenia.
    Psychopharmacology, 1995, Volume: 117, Issue:4

    Topics: Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Fluphenazine; Haloperidol; Human

1995
Adjunctive fluoxetine in the treatment of negative symptoms in chronic schizophrenic patients.
    International clinical psychopharmacology, 1994,Winter, Volume: 9, Issue:4

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Female

1994
Serum concentrations of clozapine and its major metabolites: effects of cotreatment with fluoxetine or valproate.
    The American journal of psychiatry, 1994, Volume: 151, Issue:1

    Topics: Adult; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Comb

1994
Fluoxetine augmentation of clozapine treatment in patients with schizophrenia.
    The American journal of psychiatry, 1996, Volume: 153, Issue:12

    Topics: Adult; Ambulatory Care; Clozapine; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetin

1996
Interaction between fluoxetine and haloperidol: pharmacokinetic and clinical implications.
    Pharmacological research, 1997, Volume: 35, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Drug Interactions; Female; Fl

1997
Pharmacoclinical strategy in neuroleptic resistant schizophrenic patients treated by clozapine: clinical evolution, concentration of plasma and red blood cell clozapine and desmethylclozapine, whole blood serotonin and tryptophan.
    Progress in neuro-psychopharmacology & biological psychiatry, 1999, Volume: 23, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brief Psychiatric Rating Scal

1999
Fluoxetine as an adjunct to conventional antipsychotic treatment of schizophrenia patients with residual symptoms.
    The Journal of nervous and mental disease, 2000, Volume: 188, Issue:1

    Topics: Adult; Ambulatory Care; Antipsychotic Agents; Double-Blind Method; Drug Administration Schedule; Dru

2000
Effect of fluoxetine and imipramine on the pharmacokinetics and tolerability of the antipsychotic quetiapine.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bipolar Disorder;

2002
Olanzapine-induced weight gain in patients with first-episode schizophrenia: a double-blind, placebo-controlled study of fluoxetine addition.
    The American journal of psychiatry, 2002, Volume: 159, Issue:6

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Double-Blind Method; Drug Therapy, Co

2002
Addition of fluoxetine to treatment of schizophrenic patients.
    The American journal of psychiatry, 1991, Volume: 148, Issue:2

    Topics: Antipsychotic Agents; Drug Therapy, Combination; Fluoxetine; Humans; Male; Psychotic Disorders; Schi

1991
Trial of fluoxetine added to neuroleptics for treatment-resistant schizophrenic patients.
    The American journal of psychiatry, 1990, Volume: 147, Issue:4

    Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Depression; Drug Therapy, Combination; Female

1990
Is compulsive drinking a compulsive behavior? A pilot study.
    Biological psychiatry, 1991, Mar-01, Volume: 29, Issue:5

    Topics: Adult; Compulsive Behavior; Drinking; Fluoxetine; Humans; Male; Pilot Projects; Schizophrenia; Schiz

1991

Other Studies

51 other studies available for fluoxetine and Schizophrenia

ArticleYear
Fluoxetine-induced pulmonary hypertension in a patient with schizophrenia.
    The Journal of neuropsychiatry and clinical neurosciences, 2014,Fall, Volume: 26, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Female; Fluoxetine; Humans; Hypertension, Pulmonary

2014
Lower [3H]LY341495 binding to mGlu2/3 receptors in the anterior cingulate of subjects with major depressive disorder but not bipolar disorder or schizophrenia.
    Journal of affective disorders, 2016, Jan-15, Volume: 190

    Topics: Amino Acids; Animals; Antidepressive Agents; Bipolar Disorder; Brain; Depressive Disorder, Major; Ex

2016
Fluoxetine Adjunctive Therapy for Obsessive-Compulsive Symptoms Associated With Olanzapine in Schizophrenic Patients.
    Journal of clinical psychopharmacology, 2016, Volume: 36, Issue:4

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Female; Fluoxetine; Humans;

2016
Nasal bleeding associated with fluoxetine and risperidone interaction: a case report.
    Pharmacopsychiatry, 2009, Volume: 42, Issue:5

    Topics: Depression; Drug Interactions; Epistaxis; Fluoxetine; Follow-Up Studies; Humans; Male; Risperidone;

2009
Paraphilias in schizophrenia: differential diagnosis and treatment with selective serotonin reuptake inhibitors.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Aug-16, Volume: 34, Issue:6

    Topics: Diagnosis, Differential; Fluoxetine; Humans; Male; Middle Aged; Paraphilic Disorders; Schizophrenia;

2010
Raynaud’s phenomenon in a patient with schizophrenia and obsessive-compulsive disorder: a case report.
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2011,Summer, Volume: 22, Issue:2

    Topics: Amlodipine; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Clonaze

2011
Impaired cognitive function and altered hippocampal synapse morphology in mice lacking Lrrtm1, a gene associated with schizophrenia.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Adaptation, Psychological; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Cognition; Di

2011
Fluoxetine and aripiprazole treatment following prenatal immune activation exert longstanding effects on rat locomotor response.
    Physiology & behavior, 2012, May-15, Volume: 106, Issue:2

    Topics: Acute-Phase Reaction; Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Disease Models, Anim

2012
Repeated activation of mania by atypical antipsychotics in a patient.
    BMJ case reports, 2012, Nov-27, Volume: 2012

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Substitution; Drug Therapy, Combinatio

2012
Serotonin reuptake inhibitor treatment of obsessive-compulsive symptoms in clozapine-medicated schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:11

    Topics: Adult; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Clomipramine; Clozapine; Comorbidity; Cy

2012
Inhibition of risperidone metabolism by fluoxetine in patients with schizophrenia: a clinically relevant pharmacokinetic drug interaction.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:4

    Topics: Adult; Antipsychotic Agents; Depression; Drug Interactions; Drug Therapy, Combination; Female; Fluox

2002
Reply to Dr Mahendran. We have not found reported cases of [obsessive-compulsive] OC arising from de novo with olanzapine treatment.
    The Australian and New Zealand journal of psychiatry, 2003, Volume: 37, Issue:1

    Topics: Adult; Benzodiazepines; Clomipramine; Fluoxetine; Humans; Male; Obsessive-Compulsive Disorder; Olanz

2003
Electrophysiological effects of acute and chronic olanzapine and fluoxetine in the rat prefrontal cortex.
    Neuroscience letters, 2003, Oct-09, Volume: 349, Issue:3

    Topics: Action Potentials; Animals; Benzodiazepines; Depressive Disorder; Dose-Response Relationship, Drug;

2003
Fluoxetine augmentation of haloperidol in chronic schizophrenia.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:5

    Topics: Adult; Chi-Square Distribution; Chronic Disease; Drug Synergism; Female; Fluoxetine; Haloperidol; Hu

2003
Obsessive-compulsive symptoms in schizophrenia induced by risperidone and responding to fluoxetine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2003, Volume: 48, Issue:10

    Topics: Antipsychotic Agents; Chronic Disease; Fluoxetine; Humans; Male; Middle Aged; Obsessive-Compulsive D

2003
Treatment outcome of schizophrenia co-morbid with obsessive-compulsive disorder.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2004, Volume: 14, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Comorbidity; Fluoxetine; Huma

2004
Reply to Dr. J-C Shim and colleagues regarding "Fluoxetine augmentation of haloperidol in chronic schizophrenia" [J Clin Psychopharmacol 2003;23:520-521].
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:6

    Topics: Drug Synergism; Drug Therapy, Combination; Fluoxetine; Haloperidol; Humans; Schizophrenia

2004
Excessive weight gain after remission of depression in a schizophrenic patient treated with risperidone: case report.
    BMC psychiatry, 2006, Sep-05, Volume: 6

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bulimia; Depression; Diabetes

2006
A case of fluoxetine-induced syndrome of inappropriate antidiuretic hormone secretion.
    Nature clinical practice. Nephrology, 2008, Volume: 4, Issue:5

    Topics: Fluoxetine; Follow-Up Studies; Humans; Inappropriate ADH Syndrome; Male; Middle Aged; Risk Assessmen

2008
Brain serotonin receptors and neuropsychiatric disorders.
    Advances in experimental medicine and biology, 1981, Volume: 133

    Topics: Animals; Brain; Desipramine; Fluoxetine; Humans; Imipramine; Kinetics; Lysergic Acid Diethylamide; M

1981
Delirium: an SSRI-benztropine adverse effect?
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:11

    Topics: Adult; Age Factors; Aged; Benztropine; Delirium; Drug Interactions; Fluoxetine; Humans; Middle Aged;

1995
[Personality disorders and obsessive-compulsive disorder: critical analysis of the literature data and our studies].
    Minerva psichiatrica, 1995, Volume: 36, Issue:1

    Topics: Clomipramine; Comorbidity; Depressive Disorder; Fluoxetine; Humans; Obsessive-Compulsive Disorder; P

1995
Precipitation of a psychoneuromotor syndrome by fluoxetine in a haloperidol-treated schizophrenic patient.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:5

    Topics: Akathisia, Drug-Induced; Drug Therapy, Combination; Fluoxetine; Haloperidol; Humans; Male; Middle Ag

1994
Fluoxetine for the prolonged treatment of schizophreniform psychosis.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1995, Volume: 40, Issue:1

    Topics: Adult; Drug Therapy, Combination; Female; Fluoxetine; Humans; Long-Term Care; Male; Psychotic Disord

1995
Cyproheptadine in treatment-resistant chronic schizophrenics with prior negative response to fluoxetine.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:6

    Topics: Adult; Aged; Antipsychotic Agents; Chronic Disease; Cyproheptadine; Depressive Disorder; Drug Therap

1994
Exacerbation of obsessive-compulsive symptoms associated with clozapine.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:5

    Topics: Adult; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Comb

1994
Lack of effect of fluoxetine on plasma clozapine concentrations.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:10

    Topics: Adult; Clozapine; Drug Interactions; Drug Therapy, Combination; Fluoxetine; Humans; Male; Schizophre

1994
Treatment of obsessive-compulsive symptoms in schizophrenia with a neuroleptic-selective serotonin reuptake inhibitor combination: two case reports.
    The Journal of nervous and mental disease, 1994, Volume: 182, Issue:12

    Topics: Adult; Aged; Antipsychotic Agents; Clomipramine; Drug Therapy, Combination; Fluoxetine; Humans; Male

1994
Treatment of schizophrenia with obsessive-compulsive features with serotonin reuptake inhibitors.
    The American journal of psychiatry, 1993, Volume: 150, Issue:7

    Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Fluoxetine; Humans; Male; Obsessive-Compulsi

1993
Fluoxetine for obsessional symptoms in schizophrenia.
    The American journal of psychiatry, 1994, Volume: 151, Issue:1

    Topics: Adult; Female; Fluoxetine; Humans; Obsessive-Compulsive Disorder; Schizophrenia; Schizophrenic Psych

1994
Clozapine, obsessive symptoms, and serotonergic mechanisms.
    The American journal of psychiatry, 1993, Volume: 150, Issue:9

    Topics: Clozapine; Drug Therapy, Combination; Fluoxetine; Humans; Obsessive-Compulsive Disorder; Schizophren

1993
Managing psychotic symptoms when the diagnosis is unclear.
    Hospital & community psychiatry, 1993, Volume: 44, Issue:2

    Topics: Adult; Diagnosis, Differential; Fluoxetine; Fluphenazine; Humans; Male; Obsessive-Compulsive Disorde

1993
Development of obsessive-compulsive symptoms during clozapine treatment.
    The American journal of psychiatry, 1993, Volume: 150, Issue:5

    Topics: Adult; Clozapine; Female; Fluoxetine; Humans; Obsessive-Compulsive Disorder; Schizophrenia

1993
Neuroleptic-induced tardive dyskinesia.
    The American journal of psychiatry, 1996, Volume: 153, Issue:5

    Topics: Adolescent; Basal Ganglia Diseases; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Fluoxetine;

1996
Serum levels of clozapine and norclozapine in patients treated with selective serotonin reuptake inhibitors.
    The American journal of psychiatry, 1996, Volume: 153, Issue:6

    Topics: 1-Naphthylamine; Adult; Affective Disorders, Psychotic; Aged; Ambulatory Care; Clozapine; Drug Inter

1996
Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs.
    Acta psychiatrica Scandinavica, 1996, Volume: 93, Issue:1

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Dipeptidy

1996
Selective serotonin reuptake inhibitor modulation of clozapine effects on cognition in schizophrenia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:1

    Topics: 1-Naphthylamine; Adult; Antipsychotic Agents; Clozapine; Cognition; Depressive Disorder; Drug Synerg

1998
Effect of fluoxetine on the plasma concentrations of clozapine and its major metabolites in patients with schizophrenia.
    International clinical psychopharmacology, 1998, Volume: 13, Issue:3

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Biotransformation; Chronic Di

1998
[Severe tardive dyskinesia during treatment with risperidone and fluoxetine].
    Nederlands tijdschrift voor geneeskunde, 1998, Jun-27, Volume: 142, Issue:26

    Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Fluoxetine; Humans

1998
Risperidone for exclusively negative symptoms.
    The American journal of psychiatry, 1999, Volume: 156, Issue:2

    Topics: Adult; Antipsychotic Agents; Drug Administration Schedule; Drug Therapy, Combination; Fluoxetine; Hu

1999
Obsessive-compulsive symptoms with risperidone.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:4

    Topics: Antipsychotic Agents; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fluox

1999
Olanzapine-induced obsessive-compulsive disorder.
    The American journal of psychiatry, 1999, Volume: 156, Issue:5

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clomipramine; Fluoxetine; Humans; Male; Obsessive-Comp

1999
Selective serotonin reuptake inhibitor syndrome: precipitated by concomitant clozapine?
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:4

    Topics: Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluoxe

1999
Treating depression in schizophrenia.
    The American journal of psychiatry, 2001, Volume: 158, Issue:9

    Topics: Antidepressive Agents; Antipsychotic Agents; Clozapine; Comorbidity; Depressive Disorder; Drug Inter

2001
Addition of fluoxetine to clozapine.
    The American journal of psychiatry, 1992, Volume: 149, Issue:9

    Topics: Adult; Clozapine; Drug Therapy, Combination; Fluoxetine; Humans; Male; Schizophrenia; Schizophrenic

1992
Possible clozapine exacerbation of bulimia nervosa.
    The American journal of psychiatry, 1992, Volume: 149, Issue:10

    Topics: Acute Disease; Adult; Bulimia; Clozapine; Dyskinesia, Drug-Induced; Female; Fluoxetine; Humans; Recu

1992
Fluoxetine and schizophrenia in a patient with obsessional thinking.
    The Journal of neuropsychiatry and clinical neurosciences, 1992,Spring, Volume: 4, Issue:2

    Topics: Adult; Drug Therapy, Combination; Fluoxetine; Humans; Male; Obsessive-Compulsive Disorder; Psychoses

1992
Adjunctive fluoxetine improves global function in chronic schizophrenia.
    The Journal of neuropsychiatry and clinical neurosciences, 1990,Fall, Volume: 2, Issue:4

    Topics: Adult; Antipsychotic Agents; Chronic Disease; Compulsive Behavior; Dose-Response Relationship, Drug;

1990
Potential antidopaminergic effects of serotonin reuptake inhibitors.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:1

    Topics: Animals; Clomipramine; Dopamine Antagonists; Fluoxetine; Humans; Obsessive-Compulsive Disorder; Rats

1991
Elevation of plasma concentrations of haloperidol after the addition of fluoxetine.
    The American journal of psychiatry, 1991, Volume: 148, Issue:6

    Topics: Adult; Aged; Basal Ganglia Diseases; Drug Interactions; Drug Therapy, Combination; Female; Fluoxetin

1991
Fluoxetine in chronic schizophrenia.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:1

    Topics: Amantadine; Chronic Disease; Drug Therapy, Combination; Fluoxetine; Humans; Loxapine; Male; Middle A

1990