Page last updated: 2024-10-27

fluoxetine and Rett Syndrome

fluoxetine has been researched along with Rett Syndrome in 5 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)

Research Excerpts

ExcerptRelevanceReference
" We present a patient whose severe hyperventilation and apneic attacks resolved with the concomitant treatment of fluoxetine and buspirone."7.78Use of buspirone and fluoxetine for breathing problems in Rett syndrome. ( Ardıç, UA; Gökben, S; Serdaroğlu, G, 2012)
" We present a patient whose severe hyperventilation and apneic attacks resolved with the concomitant treatment of fluoxetine and buspirone."3.78Use of buspirone and fluoxetine for breathing problems in Rett syndrome. ( Ardıç, UA; Gökben, S; Serdaroğlu, G, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Villani, C2
Sacchetti, G2
Carli, M2
Invernizzi, RW2
Castaldo, AM1
Temudo, T1
Rios, M1
Prior, C1
Carrilho, I1
Santos, M1
Maciel, P1
Sequeiros, J1
Fonseca, M1
Monteiro, J1
Cabral, P1
Vieira, JP1
Ormazabal, A1
Artuch, R1
Pan, CH1
Tsai, S1
Gökben, S1
Ardıç, UA1
Serdaroğlu, G1

Trials

1 trial available for fluoxetine and Rett Syndrome

ArticleYear
Evaluation of CSF neurotransmitters and folate in 25 patients with Rett disorder and effects of treatment.
    Brain & development, 2009, Volume: 31, Issue:1

    Topics: Administration, Oral; Child; Child, Preschool; DNA Mutational Analysis; Female; Fluoxetine; Folic Ac

2009

Other Studies

4 other studies available for fluoxetine and Rett Syndrome

ArticleYear
Fluoxetine rescues rotarod motor deficits in Mecp2 heterozygous mouse model of Rett syndrome via brain serotonin.
    Neuropharmacology, 2020, 10-01, Volume: 176

    Topics: Animals; Brain; Female; Fluoxetine; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mi

2020
Fluoxetine increases brain MeCP2 immuno-positive cells in a female Mecp2 heterozygous mouse model of Rett syndrome through endogenous serotonin.
    Scientific reports, 2021, 07-19, Volume: 11, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Disease Models, Animal; Female; Fluoxetine; Heterozygote; Mal

2021
Early intervention with psychostimulants or antidepressants to increase methyl-CpG-binding protein 2 (MeCP2) expressions: a potential therapy for Rett syndrome.
    Medical science monitor : international medical journal of experimental and clinical research, 2012, Volume: 18, Issue:1

    Topics: Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cocaine; Early Medical Intervention; Femal

2012
Use of buspirone and fluoxetine for breathing problems in Rett syndrome.
    Pediatric neurology, 2012, Volume: 46, Issue:3

    Topics: Apnea; Buspirone; Child; Female; Fluoxetine; Humans; Hyperventilation; Rett Syndrome; Selective Sero

2012