Page last updated: 2024-10-27

fluoxetine and Premature Ejaculation

fluoxetine has been researched along with Premature Ejaculation in 9 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Premature Ejaculation: The emission of SEMEN and seminal fluid during the act of preparation for sexual intercourse, i.e. before there is penetration, or shortly after penetration.

Research Excerpts

ExcerptRelevanceReference
"The primary goal of this systematic review and meta-analysis was to compare the efficacy and safety of fluoxetine with other oral pharmaceuticals in the treatment of premature ejaculation (PE)."9.22Comparison of fluoxetine with other selective serotonin reuptake inhibitors in the treatment of premature ejaculation: A systematic review and meta-analysis. ( Dai, Y; Gao, H; Huang, Y; Jiang, H; Liu, Q; Wang, M; Zhang, X, 2022)
"To examine the relationship between premature ejaculation and plasma melatonin levels, and assess the efficacy of selective serotonin reuptake inhibitors in treating premature ejaculation."9.19Relationship between plasma melatonin levels and the efficacy of selective serotonin reuptake inhibitors treatment on premature ejaculation. ( Degirmencioglu, S; Gurbuz, ZG; Kirecci, SL; Mimaroglu, S; Simsek, A; Vural, P; Yuksel, A, 2014)
" In addition, we will carefully observe the patient's adverse reactions during the medication."6.61Effectiveness and safety of fluoxetine for premature ejaculation: Protocol for a systematic review. ( Dai, H; Li, J; Li, X; Wang, J, 2019)
"Fluoxetine is an effective agent for the treatment of PE with significant improvement realized in IELT, ejaculatory control, and distress levels for both men and their partners."5.51Compliance With Fluoxetine Use in Men With Primary Premature Ejaculation. ( Gonzalez, J; Guhring, P; Jenkins, LC; Mulhall, JP; Parker, M; Tal, R, 2019)
"The primary goal of this systematic review and meta-analysis was to compare the efficacy and safety of fluoxetine with other oral pharmaceuticals in the treatment of premature ejaculation (PE)."5.22Comparison of fluoxetine with other selective serotonin reuptake inhibitors in the treatment of premature ejaculation: A systematic review and meta-analysis. ( Dai, Y; Gao, H; Huang, Y; Jiang, H; Liu, Q; Wang, M; Zhang, X, 2022)
"To examine the relationship between premature ejaculation and plasma melatonin levels, and assess the efficacy of selective serotonin reuptake inhibitors in treating premature ejaculation."5.19Relationship between plasma melatonin levels and the efficacy of selective serotonin reuptake inhibitors treatment on premature ejaculation. ( Degirmencioglu, S; Gurbuz, ZG; Kirecci, SL; Mimaroglu, S; Simsek, A; Vural, P; Yuksel, A, 2014)
" In addition, we will carefully observe the patient's adverse reactions during the medication."2.61Effectiveness and safety of fluoxetine for premature ejaculation: Protocol for a systematic review. ( Dai, H; Li, J; Li, X; Wang, J, 2019)
"Fluoxetine is an effective agent for the treatment of PE with significant improvement realized in IELT, ejaculatory control, and distress levels for both men and their partners."1.51Compliance With Fluoxetine Use in Men With Primary Premature Ejaculation. ( Gonzalez, J; Guhring, P; Jenkins, LC; Mulhall, JP; Parker, M; Tal, R, 2019)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Liu, Q1
Gao, H1
Huang, Y1
Wang, M1
Jiang, H1
Dai, Y1
Zhang, X1
GamalEl Din, SF1
Motawi, AT1
Rashed, LA1
Elghobary, H1
Saad, HM1
Ismail, MM1
Abdel-Latif, HF1
Jenkins, LC1
Gonzalez, J1
Tal, R1
Guhring, P1
Parker, M1
Mulhall, JP1
Li, X2
Li, J1
Wang, J2
Dai, H1
Otunctemur, A1
Ozbek, E1
Kirecci, SL3
Ozcan, L1
Dursun, M1
Cekmen, M1
Ozdogan, HK1
Simsek, A2
Gurbuz, ZG2
Mimaroglu, S2
Yuksel, A2
Vural, P2
Degirmencioglu, S2
Sato, Y1
Amano, T1

Reviews

2 reviews available for fluoxetine and Premature Ejaculation

ArticleYear
Comparison of fluoxetine with other selective serotonin reuptake inhibitors in the treatment of premature ejaculation: A systematic review and meta-analysis.
    Andrologia, 2022, Volume: 54, Issue:8

    Topics: Ejaculation; Fluoxetine; Humans; Male; Paroxetine; Premature Ejaculation; Selective Serotonin Reupta

2022
Effectiveness and safety of fluoxetine for premature ejaculation: Protocol for a systematic review.
    Medicine, 2019, Volume: 98, Issue:7

    Topics: China; Fluoxetine; Humans; Male; Men's Health; Premature Ejaculation; Randomized Controlled Trials a

2019

Trials

2 trials available for fluoxetine and Premature Ejaculation

ArticleYear
Relevance of serum nitric oxide levels and the efficacy of selective serotonin reuptake inhibitors treatment on premature ejaculation: decreased nitric oxide is associated with premature ejaculation.
    Andrologia, 2014, Volume: 46, Issue:9

    Topics: Adult; Case-Control Studies; Female; Fluoxetine; Humans; Male; Middle Aged; Nitric Oxide; Paroxetine

2014
Relationship between plasma melatonin levels and the efficacy of selective serotonin reuptake inhibitors treatment on premature ejaculation.
    International journal of urology : official journal of the Japanese Urological Association, 2014, Volume: 21, Issue:9

    Topics: Adult; Fluoxetine; Humans; Male; Melatonin; Middle Aged; Paroxetine; Premature Ejaculation; Selectiv

2014

Other Studies

5 other studies available for fluoxetine and Premature Ejaculation

ArticleYear
Study of the role of microRNAs 16 and 135a in patients with lifelong premature ejaculation receiving fluoxetine daily for 3 months: A prospective case control study.
    Andrologia, 2022, Volume: 54, Issue:10

    Topics: Case-Control Studies; Ejaculation; Fluoxetine; Humans; Male; MicroRNAs; Premature Ejaculation; Time

2022
Compliance With Fluoxetine Use in Men With Primary Premature Ejaculation.
    The journal of sexual medicine, 2019, Volume: 16, Issue:12

    Topics: Adult; Ejaculation; Fluoxetine; Humans; Male; Middle Aged; Patient Compliance; Premature Ejaculation

2019
Editorial Comment from Dr Sato to Relationship between plasma melatonin levels and the efficacy of selective serotonin reuptake inhibitors treatment on premature ejaculation.
    International journal of urology : official journal of the Japanese Urological Association, 2014, Volume: 21, Issue:9

    Topics: Fluoxetine; Humans; Male; Melatonin; Paroxetine; Premature Ejaculation; Selective Serotonin Reuptake

2014
Editorial Comment from Dr Amano to Relationship between plasma melatonin levels and the efficacy of selective serotonin reuptake inhibitors treatment on premature ejaculation.
    International journal of urology : official journal of the Japanese Urological Association, 2014, Volume: 21, Issue:9

    Topics: Fluoxetine; Humans; Male; Melatonin; Paroxetine; Premature Ejaculation; Selective Serotonin Reuptake

2014
Response to Editorial Comments to Relationship between plasma melatonin levels and the efficacy of selective serotonin reuptake inhibitors treatment on premature ejaculation.
    International journal of urology : official journal of the Japanese Urological Association, 2014, Volume: 21, Issue:9

    Topics: Fluoxetine; Humans; Male; Melatonin; Paroxetine; Premature Ejaculation; Selective Serotonin Reuptake

2014