fluoxetine has been researched along with Postoperative Cognitive Complications in 2 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Postoperative Cognitive Complications: COGNITIVE IMPAIRMENT or functional decline after a surgical procedure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine pretreatment partially restored the deteriorated cognitive function, downregulated proinflammatory cytokine levels, restrained microglial activation, alleviated neural apoptosis, and suppressed the increase in TLR4, MyD88, and p-NF-κB p65 in microglia." | 1.91 | Fluoxetine alleviates postoperative cognitive dysfunction by attenuating TLR4/MyD88/NF-κB signaling pathway activation in aged mice. ( Chen, Y; Lin, D; Liu, L; Wu, Y; Yao, Y; Zheng, X, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, D | 2 |
| Yu, L | 1 |
| Chen, J | 1 |
| Ye, H | 1 |
| Wu, Y | 2 |
| Yao, Y | 2 |
| Chen, Y | 1 |
| Liu, L | 1 |
| Zheng, X | 1 |
1 trial available for fluoxetine and Postoperative Cognitive Complications
| Article | Year |
|---|---|
Fluoxetine for reducing postoperative cognitive dysfunction in elderly patients after total knee replacement: study protocol for a single-centre, double-blind, randomised, parallel-group, superiority, placebo-controlled trial.
Topics: Aged; Arthroplasty, Replacement, Knee; Double-Blind Method; Fluoxetine; Humans; Postoperative Cognit | 2022 |
1 other study available for fluoxetine and Postoperative Cognitive Complications
| Article | Year |
|---|---|
Fluoxetine alleviates postoperative cognitive dysfunction by attenuating TLR4/MyD88/NF-κB signaling pathway activation in aged mice.
Topics: Animals; Cytokines; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Microglia; Myeloid Differentiation F | 2023 |