fluoxetine has been researched along with Pain, Chronic in 8 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, pain sensitivity was assessed in a mouse model of anxiety/depression on the basis of chronic corticosterone (CORT) administration through the drinking water (CORT model)." | 7.78 | Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. ( Coudoré, F; David, DJ; Gardier, AM; Guiard, BP; Hache, G; Le Dantec, Y; Orvoën, S, 2012) |
| "Using a depression comorbidity of chronic pain rat model induced by spinal nerve ligation (SNL), we investigated the potency of T10 for the treatment of comorbid depression in comparison with a widely used antidepressant, fluoxetine (FLX)." | 5.46 | The novel and potent anti-depressive action of triptolide and its influences on hippocampal neuroinflammation in a rat model of depression comorbidity of chronic pain. ( Dong, Y; Hu, X; Jin, X; Li, J; Shi, J; Zhang, C; Zhang, T; Zhao, J, 2017) |
| "Co-administration of pioglitazone or metformin with low-dose fluoxetine improved mechanical allodynia, thermal hyperalgesia, and neurohistopathological changes while co-administration of pioglitazone, but not metformin, improved the depressive-like behavior in the peripheral nerve injury model of neuropathic pain in rats." | 3.81 | Co-Administration of Pioglitazone Improves Fluoxetine's Antinociceptive, Neuroprotective, and Antidepressant Effects in Chronic Constriction Injury in Rats. ( Ayuob, N; Murad, H, 2015) |
| " In the present study, pain sensitivity was assessed in a mouse model of anxiety/depression on the basis of chronic corticosterone (CORT) administration through the drinking water (CORT model)." | 3.78 | Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. ( Coudoré, F; David, DJ; Gardier, AM; Guiard, BP; Hache, G; Le Dantec, Y; Orvoën, S, 2012) |
| "Depression is frequently associated with chronic pain or chronic stress." | 1.46 | Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression. ( Barrot, M; Barthas, F; Belzung, C; Boutillier, AL; Gilsbach, R; Hein, L; Humo, M; Karatas, M; Leman, S; Waltisperger, E; Yalcin, I, 2017) |
| "Using a depression comorbidity of chronic pain rat model induced by spinal nerve ligation (SNL), we investigated the potency of T10 for the treatment of comorbid depression in comparison with a widely used antidepressant, fluoxetine (FLX)." | 1.46 | The novel and potent anti-depressive action of triptolide and its influences on hippocampal neuroinflammation in a rat model of depression comorbidity of chronic pain. ( Dong, Y; Hu, X; Jin, X; Li, J; Shi, J; Zhang, C; Zhang, T; Zhao, J, 2017) |
| " 10b was additionally bioavailable following oral dosing and demonstrated efficacy in rat models of acute, inflammatory, and neuropathic pain." | 1.37 | Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152). ( Adedoyin, A; Bray, JA; Deecher, DC; Fensome, A; Goldberg, JA; Harrison, J; Leventhal, L; Mann, C; Mark, L; Nogle, L; O'Neill, DJ; Spangler, TB; Sullivan, NR; Terefenko, EA; Trybulski, EJ; Uveges, AJ; Vu, A; Whiteside, GT; Zhang, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| O'Neill, DJ | 1 |
| Adedoyin, A | 1 |
| Bray, JA | 1 |
| Deecher, DC | 1 |
| Fensome, A | 1 |
| Goldberg, JA | 1 |
| Harrison, J | 1 |
| Leventhal, L | 1 |
| Mann, C | 1 |
| Mark, L | 1 |
| Nogle, L | 1 |
| Sullivan, NR | 1 |
| Spangler, TB | 1 |
| Terefenko, EA | 1 |
| Trybulski, EJ | 1 |
| Uveges, AJ | 1 |
| Vu, A | 1 |
| Whiteside, GT | 1 |
| Zhang, P | 1 |
| Nemoto, W | 3 |
| Kozak, D | 3 |
| Sotocinal, SG | 3 |
| Tansley, S | 3 |
| Bannister, K | 3 |
| Mogil, JS | 3 |
| Barthas, F | 1 |
| Humo, M | 1 |
| Gilsbach, R | 1 |
| Waltisperger, E | 1 |
| Karatas, M | 1 |
| Leman, S | 1 |
| Hein, L | 1 |
| Belzung, C | 1 |
| Boutillier, AL | 1 |
| Barrot, M | 1 |
| Yalcin, I | 1 |
| Luk, S | 1 |
| Atayee, RS | 1 |
| Ma, JD | 1 |
| Best, BM | 1 |
| Hearn, L | 1 |
| Moore, RA | 1 |
| Derry, S | 1 |
| Wiffen, PJ | 1 |
| Phillips, T | 1 |
| Murad, H | 1 |
| Ayuob, N | 1 |
| Hu, X | 1 |
| Dong, Y | 1 |
| Jin, X | 1 |
| Zhang, C | 1 |
| Zhang, T | 1 |
| Zhao, J | 1 |
| Shi, J | 1 |
| Li, J | 1 |
| Hache, G | 1 |
| Guiard, BP | 1 |
| Le Dantec, Y | 1 |
| Orvoën, S | 1 |
| David, DJ | 1 |
| Gardier, AM | 1 |
| Coudoré, F | 1 |
1 review available for fluoxetine and Pain, Chronic
| Article | Year |
|---|---|
Desipramine for neuropathic pain in adults.
Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Pain; Clomipramine; Desip | 2014 |
7 other studies available for fluoxetine and Pain, Chronic
| Article | Year |
|---|---|
Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).
Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Benzothiazoles; Biological Availability; Cell | 2011 |
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.
Topics: Analgesics; Animals; Chronic Pain; Fluoxetine; Hyperalgesia; Mice; Nociception; Norepinephrine; Rats | 2023 |
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.
Topics: Analgesics; Animals; Chronic Pain; Fluoxetine; Hyperalgesia; Mice; Nociception; Norepinephrine; Rats | 2023 |
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.
Topics: Analgesics; Animals; Chronic Pain; Fluoxetine; Hyperalgesia; Mice; Nociception; Norepinephrine; Rats | 2023 |
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.
Topics: Analgesics; Animals; Chronic Pain; Fluoxetine; Hyperalgesia; Mice; Nociception; Norepinephrine; Rats | 2023 |
Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression.
Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Pain; Depressive Disorder; Disease Models | 2017 |
Urinary diazepam metabolite distribution in a chronic pain population.
Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chronic Pain; Cytochrome P-450 | 2014 |
Co-Administration of Pioglitazone Improves Fluoxetine's Antinociceptive, Neuroprotective, and Antidepressant Effects in Chronic Constriction Injury in Rats.
Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Chronic Pain; Constriction, Pathologi | 2015 |
The novel and potent anti-depressive action of triptolide and its influences on hippocampal neuroinflammation in a rat model of depression comorbidity of chronic pain.
Topics: Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Chronic Pain; Depression; Disease Mode | 2017 |
Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Chronic Pain; Cold Temperature; Corticos | 2012 |