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fluoxetine and Neuroleptic Malignant Syndrome

fluoxetine has been researched along with Neuroleptic Malignant Syndrome in 7 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
"The authors present a case report of neuroleptic malignant syndrome (NMS) in a patient commencing treatment with fluoxetine alone who had previously been treated with several antipsychotic and antidepressant combinations."7.68Fluoxetine and neuroleptic malignant syndrome. ( Goldbloom, DS; Halman, M, 1990)
"Case 2 was a female with schizoaffective disorder without a history of NMS."6.52Atypical neuroleptic malignant syndrome in patients treated with aripiprazole and clozapine: a case-series study and short review. ( Chang, CH; Chang, YC; Chen, YW; Cheng, YS; Chung, W; Tseng, PT; Wang, HY; Wu, CK, 2015)
"The authors present a case report of neuroleptic malignant syndrome (NMS) in a patient commencing treatment with fluoxetine alone who had previously been treated with several antipsychotic and antidepressant combinations."3.68Fluoxetine and neuroleptic malignant syndrome. ( Goldbloom, DS; Halman, M, 1990)
"Case 2 was a female with schizoaffective disorder without a history of NMS."2.52Atypical neuroleptic malignant syndrome in patients treated with aripiprazole and clozapine: a case-series study and short review. ( Chang, CH; Chang, YC; Chen, YW; Cheng, YS; Chung, W; Tseng, PT; Wang, HY; Wu, CK, 2015)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tseng, PT1
Chang, YC1
Chang, CH1
Wang, HY1
Cheng, YS1
Wu, CK1
Chen, YW1
Chung, W1
Birmes, P1
Coppin, D1
Schmitt, L1
Lauque, D1
Duggal, HS1
Kithas, J1
Nimmo, SM1
Kennedy, BW1
Tullett, WM1
Blyth, AS1
Dougall, JR1
Calvo Villas, JM1
Zapata Ramos, F1
Lluch Perales, J1
GarcĂ­a Zerpa, C1
Sternbach, H1
Halman, M1
Goldbloom, DS1

Reviews

3 reviews available for fluoxetine and Neuroleptic Malignant Syndrome

ArticleYear
Atypical neuroleptic malignant syndrome in patients treated with aripiprazole and clozapine: a case-series study and short review.
    International journal of psychiatry in medicine, 2015, Volume: 49, Issue:1

    Topics: Adult; Aripiprazole; Clozapine; Creatine Kinase; Dose-Response Relationship, Drug; Drug Substitution

2015
Serotonin syndrome: a brief review.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, May-27, Volume: 168, Issue:11

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Diagnosis, Differential; Female; Fluid Therapy

2003
The serotonin syndrome.
    The American journal of psychiatry, 1991, Volume: 148, Issue:6

    Topics: Adult; Antidepressive Agents; Basal Ganglia Diseases; Depressive Disorder; Drug Interactions; Drug T

1991

Other Studies

4 other studies available for fluoxetine and Neuroleptic Malignant Syndrome

ArticleYear
Possible neuroleptic malignant syndrome with aripiprazole and fluoxetine.
    The American journal of psychiatry, 2005, Volume: 162, Issue:2

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Depressive Disorder; Drug Therapy, Combination; Fluoxetin

2005
Drug-induced hyperthermia.
    Anaesthesia, 1993, Volume: 48, Issue:10

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Fluoxetine; Humans; Male; Middle Aged;

1993
[Neurileptic malignant syndrome. A case associated with halazepam and fluoxetine treatment].
    Anales de medicina interna (Madrid, Spain : 1984), 2000, Volume: 17, Issue:9

    Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Female; Fluoxetine; Humans; Neur

2000
Fluoxetine and neuroleptic malignant syndrome.
    Biological psychiatry, 1990, Sep-15, Volume: 28, Issue:6

    Topics: Depressive Disorder; Drug Therapy, Combination; Fluoxetine; Humans; Male; Middle Aged; Neuroleptic M

1990