fluoxetine has been researched along with Nerve Pain in 13 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The current study assessed whether antidepressant and/or antinociceptive drugs, duloxetine, fluoxetine as well as (±)-8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT), are able to reverse depression-like behaviour in animals with chronic neuropathic pain." | 7.83 | Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain. ( Ceci, A; Doods, H; Hu, B; Treede, RD, 2016) |
| "Amitriptyline, a non-selective noradrenaline (NA) and 5-hydroxytryptamine (5-HT) reuptake inhibitor, has recently been demonstrated to produce a peripheral antinociceptive action in an inflammatory (formalin test) and a neuropathic pain model (spinal nerve ligation)." | 7.70 | Peripheral antinociceptive actions of desipramine and fluoxetine in an inflammatory and neuropathic pain test in the rat. ( Esser, MJ; Reid, AR; Sawynok, J, 1999) |
| " However, MS mice treated with fluoxetine for 4 weeks after MS did not exhibit augmentation of allodynia, and their emotional response was attenuated." | 3.91 | Maternal separation as a risk factor for aggravation of neuropathic pain in later life in mice. ( Fukumoto, K; Jin, S; Mizoguchi, H; Sakamoto, G; Sato, J; Suzumura, A; Toyama, A; Wang, T, 2019) |
| "The current study assessed whether antidepressant and/or antinociceptive drugs, duloxetine, fluoxetine as well as (±)-8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT), are able to reverse depression-like behaviour in animals with chronic neuropathic pain." | 3.83 | Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain. ( Ceci, A; Doods, H; Hu, B; Treede, RD, 2016) |
| "Amitriptyline, a non-selective noradrenaline (NA) and 5-hydroxytryptamine (5-HT) reuptake inhibitor, has recently been demonstrated to produce a peripheral antinociceptive action in an inflammatory (formalin test) and a neuropathic pain model (spinal nerve ligation)." | 3.70 | Peripheral antinociceptive actions of desipramine and fluoxetine in an inflammatory and neuropathic pain test in the rat. ( Esser, MJ; Reid, AR; Sawynok, J, 1999) |
| "All nine drugs can relieve the pain of CPSP patients to different degrees; among them pregabalin and gabapentin have the most significant effect, and gabapentin and pregabalin also have the most adverse reactions." | 2.82 | Efficacy and safety of different antidepressants and anticonvulsants in central poststroke pain: A network meta-analysis and systematic review. ( Chen, KY; Li, RY, 2022) |
| "Current drug treatment available for neuropathic pain (NP) provides meager and partial pain relief due to incomplete efficacy and dose-dependent adverse effect." | 1.51 | Comparison of sildenafil, fluoxetine and its co-administration against chronic constriction injury induced neuropathic pain in rats: An influential additive effect. ( Gill, SBS; Gulati, M; Jyoti, J; Kumar, B; Kumar, S; Melkani, I; Panchal, S; Pandey, NK; Singh, A; Singh, SK; Subedi, B, 2019) |
| "Our studies examined the neuropathic pain-relieving properties after intraperitoneal injection of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine 7 days after sciatic nerve injury (CCI) in rats and its influence on microglia/macrophages (IBA-1) and astroglia (GFAP) activation in the spinal cord and dorsal root ganglia (DRG) using Western blot." | 1.42 | The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain. ( Makuch, W; Mika, J; Przewlocka, B; Rojewska, E; Zychowska, M, 2015) |
| "Fluoxetine has been shown to be effective in clinical and experimental studies of neuropathic pain." | 1.40 | Serotonergic modulation in neuropathy induced by oxaliplatin: effect on the 5HT2C receptor. ( Baptista-de-Souza, D; Canto-de-Souza, A; Di Cesare Mannelli, L; Ghelardini, C; Micheli, L; Nunes-de-Souza, RL; Zanardelli, M, 2014) |
| " 10b was additionally bioavailable following oral dosing and demonstrated efficacy in rat models of acute, inflammatory, and neuropathic pain." | 1.37 | Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152). ( Adedoyin, A; Bray, JA; Deecher, DC; Fensome, A; Goldberg, JA; Harrison, J; Leventhal, L; Mann, C; Mark, L; Nogle, L; O'Neill, DJ; Spangler, TB; Sullivan, NR; Terefenko, EA; Trybulski, EJ; Uveges, AJ; Vu, A; Whiteside, GT; Zhang, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| O'Neill, DJ | 1 |
| Adedoyin, A | 1 |
| Bray, JA | 1 |
| Deecher, DC | 1 |
| Fensome, A | 1 |
| Goldberg, JA | 1 |
| Harrison, J | 1 |
| Leventhal, L | 1 |
| Mann, C | 1 |
| Mark, L | 1 |
| Nogle, L | 1 |
| Sullivan, NR | 1 |
| Spangler, TB | 1 |
| Terefenko, EA | 1 |
| Trybulski, EJ | 1 |
| Uveges, AJ | 1 |
| Vu, A | 1 |
| Whiteside, GT | 1 |
| Zhang, P | 1 |
| Foley, P | 1 |
| Parker, RA | 1 |
| de Angelis, F | 1 |
| Connick, P | 1 |
| Chandran, S | 1 |
| Young, C | 1 |
| Weir, CJ | 1 |
| Chataway, J | 1 |
| Chen, KY | 1 |
| Li, RY | 1 |
| Chen, M | 1 |
| Hoshino, H | 1 |
| Saito, S | 1 |
| Yang, Y | 1 |
| Obata, H | 1 |
| Mizoguchi, H | 1 |
| Fukumoto, K | 1 |
| Sakamoto, G | 1 |
| Jin, S | 1 |
| Toyama, A | 1 |
| Wang, T | 1 |
| Suzumura, A | 1 |
| Sato, J | 1 |
| Melkani, I | 1 |
| Kumar, B | 1 |
| Panchal, S | 1 |
| Singh, SK | 1 |
| Singh, A | 1 |
| Gulati, M | 1 |
| Gill, SBS | 1 |
| Jyoti, J | 1 |
| Pandey, NK | 1 |
| Kumar, S | 1 |
| Subedi, B | 1 |
| Baptista-de-Souza, D | 1 |
| Di Cesare Mannelli, L | 1 |
| Zanardelli, M | 1 |
| Micheli, L | 1 |
| Nunes-de-Souza, RL | 1 |
| Canto-de-Souza, A | 1 |
| Ghelardini, C | 1 |
| Zychowska, M | 1 |
| Rojewska, E | 1 |
| Makuch, W | 1 |
| Przewlocka, B | 1 |
| Mika, J | 1 |
| Hu, B | 1 |
| Doods, H | 1 |
| Treede, RD | 1 |
| Ceci, A | 1 |
| Bannister, K | 1 |
| Lockwood, S | 1 |
| Goncalves, L | 1 |
| Patel, R | 1 |
| Dickenson, AH | 1 |
| Goettl, VM | 1 |
| Huang, Y | 1 |
| Hackshaw, KV | 1 |
| Stephens, RL | 1 |
| Sounvoravong, S | 1 |
| Nakashima, MN | 1 |
| Wada, M | 1 |
| Nakashima, K | 1 |
| Sawynok, J | 1 |
| Esser, MJ | 1 |
| Reid, AR | 1 |
1 review available for fluoxetine and Nerve Pain
| Article | Year |
|---|---|
Efficacy and safety of different antidepressants and anticonvulsants in central poststroke pain: A network meta-analysis and systematic review.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Carbamazepine; Duloxetine Hydrochloride; Fluo | 2022 |
1 trial available for fluoxetine and Nerve Pain
| Article | Year |
|---|---|
Efficacy of Fluoxetine, Riluzole and Amiloride in treating neuropathic pain associated with secondary progressive multiple sclerosis. Pre-specified analysis of the MS-SMART double-blind randomised placebo-controlled trial.
Topics: Adult; Amiloride; Double-Blind Method; Fluoxetine; Humans; Multiple Sclerosis; Multiple Sclerosis, C | 2022 |
11 other studies available for fluoxetine and Nerve Pain
| Article | Year |
|---|---|
Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).
Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Benzothiazoles; Biological Availability; Cell | 2011 |
Spinal dopaminergic involvement in the antihyperalgesic effect of antidepressants in a rat model of neuropathic pain.
Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclopropanes; Disease Models, Animal; Do | 2017 |
Maternal separation as a risk factor for aggravation of neuropathic pain in later life in mice.
Topics: Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Calcium-Binding Proteins; Disea | 2019 |
Comparison of sildenafil, fluoxetine and its co-administration against chronic constriction injury induced neuropathic pain in rats: An influential additive effect.
Topics: Analgesics; Animals; Drug Therapy, Combination; Female; Fluoxetine; Male; Neuralgia; Rats; Rats, Spr | 2019 |
Serotonergic modulation in neuropathy induced by oxaliplatin: effect on the 5HT2C receptor.
Topics: Animals; Brain; Fluoxetine; Male; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Rats, Sprague-Da | 2014 |
The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain.
Topics: Amitriptyline; Animals; Antidepressive Agents; Calcium-Binding Proteins; Cyclohexanols; Cyclopropane | 2015 |
Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Neurons; Analgesics; Animals; Antidepressive Agen | 2016 |
An investigation into the inhibitory function of serotonin in diffuse noxious inhibitory controls in the neuropathic rat.
Topics: Animals; Diffuse Noxious Inhibitory Control; Fluoxetine; Male; Neuralgia; Neurons; Phenols; Prilocai | 2017 |
Reduced basal release of serotonin from the ventrobasal thalamus of the rat in a model of neuropathic pain.
Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Fluoxetine; Hypothalamus; Lig | 2002 |
Modification of antiallodynic and antinociceptive effects of morphine by peripheral and central action of fluoxetine in a neuropathic mice model.
Topics: Analgesics; Analysis of Variance; Animals; Drug Therapy, Combination; Fluoxetine; Ligation; Male; Mi | 2007 |
Peripheral antinociceptive actions of desipramine and fluoxetine in an inflammatory and neuropathic pain test in the rat.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Caffeine; Desipramine; Drug Evaluation, Precli | 1999 |