fluoxetine has been researched along with Muscle Contraction in 37 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluoxetine (FLX) is an antidepressant worldwide prescribed throughout life stages, including pregnancy and breastfeeding." | 3.83 | Does fish oil or folic acid prevent vascular changes in female progeny caused by maternal exposure to fluoxetine? ( Barbosa, DS; Ceravolo, GS; Gameiro, JG; Higachi, L; Higashi, CM; Matsumoto, AK; Moreira, EG; Moura, KF; Oliveira, LC, 2016) |
| " We examined whether P4 treatment could reduce the stool output in two mouse diarrheal models because of higher 5-HT levels, the SERT knock-out (KO), and the fluoxetine-treated mice." | 3.78 | Effect of progesterone on colonic motility and fecal output in mice with diarrhea. ( Behar, J; Biancani, P; Li, CP; Ling, C, 2012) |
| " Intrathecal injection of 5-methoxy-N,N'-dimethyltryptamine (5-MeODMT), (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) or 2,5-dimethoxy-alpha,4-dimethylbenzene ethamine hydrochloride (DOM) produced dose-related back muscle contractions (BMC) and wet dog shakes (WDS) which were both markedly attenuated by intraperitoneal pretreatment with either ritanserin (1 mg kg-1), ketanserin (0." | 3.68 | Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats. ( Fone, KC; Marsden, CA; Robinson, AJ, 1991) |
| "Fluoxetine was added in concentrations from 0." | 1.33 | Effects of the selective serotonin reuptake inhibitor, fluoxetine, on regional gastric contractility. ( James, AN; Parkman, HP; Ryan, JP, 2005) |
| "Clomipramine was the most potent drug for inhibition of elevation in intraluminal pressure of the rat vas deferens induced by electrical stimulation of the rat hypogastric nerve." | 1.31 | Inhibitory effect of serotonergic drugs on contractile response of the rat vas deferens to electrical nerve stimulation: in vivo study. ( Han, JH; Kim, SC; Lee, MY; Seo, KK, 2000) |
| "Clomipramine was about 100-fold more potent than sertraline, fluoxetine or paroxetine for inhibiting the norepinephrine induced contraction of human vasal muscle strips." | 1.31 | Comparison of peripheral inhibitory effects of clomipramine with selective serotonin re-uptake inhibitors on contraction of vas deferens: in vitro and in vivo studies. ( Kim, SC; Lee, MY; Seo, KK, 2001) |
| "Fluoxetine treatment did not modify the binding parameters of [3H]-prazosin to vas deferens." | 1.30 | Long-term treatment with fluoxetine associates with peripheral effects on rat vas deferens contractility. ( Borda, E; Busch, L; Wald, M, 1999) |
| "Nisoxetine was also less potent than desipramine in inhibiting responses to histamine, carbachol and bradykinin on the guinea-pig isolated ileum." | 1.27 | Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake. ( Foley, AJ; Leedham, JA; Pennefather, JN, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (24.32) | 18.7374 |
| 1990's | 6 (16.22) | 18.2507 |
| 2000's | 12 (32.43) | 29.6817 |
| 2010's | 9 (24.32) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Mizutani, H | 1 |
| Sakakibara, F | 1 |
| Sasaki, E | 1 |
| Higashi, CM | 1 |
| Matsumoto, AK | 1 |
| Gameiro, JG | 1 |
| Moura, KF | 1 |
| Higachi, L | 1 |
| Oliveira, LC | 1 |
| Barbosa, DS | 1 |
| Moreira, EG | 1 |
| Ceravolo, GS | 1 |
| Khin, PP | 1 |
| Zaw, TS | 1 |
| Sohn, UD | 1 |
| Birowo, P | 1 |
| Uckert, S | 1 |
| Kedia, GT | 1 |
| Scheller, F | 1 |
| Meyer, M | 1 |
| Taher, A | 1 |
| Rahardjo, D | 1 |
| Jonas, U | 1 |
| Kuczyk, MA | 1 |
| Göçmez, SS | 1 |
| Utkan, T | 1 |
| Ulak, G | 1 |
| Gacar, N | 1 |
| Erden, F | 1 |
| Farajian-Mashhadi, F | 1 |
| Naylor, RJ | 1 |
| Javid, FA | 1 |
| Zhang, YJ | 1 |
| Huang, X | 1 |
| Wang, Y | 1 |
| Xie, Y | 1 |
| Qiu, XJ | 1 |
| Ren, P | 1 |
| Gao, LC | 1 |
| Zhou, HH | 1 |
| Zhang, HY | 1 |
| Qiao, MQ | 1 |
| Li, CP | 1 |
| Ling, C | 1 |
| Biancani, P | 1 |
| Behar, J | 1 |
| Ribback, S | 1 |
| Pavlovic, D | 1 |
| Herbst, D | 1 |
| Nedeljkov-Jancic, R | 1 |
| Wendt, M | 1 |
| Nedeljkov, V | 1 |
| Bleich, S | 1 |
| Frieling, H | 1 |
| Jurkiewicz, NH | 2 |
| da Silva Júnior, ED | 1 |
| de Souza, BP | 1 |
| Ferreira Verde, L | 1 |
| Drawanz Pereira, J | 1 |
| Mendes Sobrinho, C | 1 |
| Soubhi Smaili, S | 1 |
| Caricati-Neto, A | 2 |
| Miranda-Ferreira, R | 1 |
| Jurkiewicz, A | 2 |
| Ellis, M | 1 |
| Chambers, JD | 1 |
| Gwynne, RM | 1 |
| Bornstein, JC | 1 |
| Mousavizadeh, K | 1 |
| Ghafourifar, P | 1 |
| Sadeghi-Nejad, H | 1 |
| Dénes, V | 1 |
| Lázár, Z | 1 |
| Barthó, L | 1 |
| Gábriel, R | 1 |
| James, AN | 1 |
| Ryan, JP | 1 |
| Parkman, HP | 1 |
| Choy, RK | 1 |
| Kemner, JM | 1 |
| Thomas, JH | 1 |
| Pereira, JD | 1 |
| Patil, MR | 1 |
| Satia, MC | 1 |
| Mehta, AA | 1 |
| Goyal, RK | 1 |
| Springer, JP | 1 |
| Kropp, BP | 1 |
| Thor, KB | 1 |
| Pescatori, ES | 1 |
| Engelman, JC | 1 |
| Davis, G | 1 |
| Goldstein, I | 1 |
| Busch, L | 3 |
| Wald, M | 3 |
| Borda, E | 3 |
| Pubill, D | 1 |
| Canudas, AM | 1 |
| Pallàs, M | 1 |
| Sureda, FX | 1 |
| Escubedo, E | 1 |
| Camins, A | 1 |
| Camarasa, J | 1 |
| Sterin-Borda, L | 1 |
| Medina, P | 1 |
| Segarra, G | 1 |
| Ballester, R | 1 |
| Chuan, P | 1 |
| Domenech, C | 1 |
| Vila, JM | 1 |
| Lluch, S | 1 |
| Kim, SC | 2 |
| Seo, KK | 2 |
| Han, JH | 1 |
| Lee, MY | 2 |
| Parise, G | 1 |
| Bosman, MJ | 1 |
| Boecker, DR | 1 |
| Barry, MJ | 1 |
| Tarnopolsky, MA | 1 |
| Pax, R | 1 |
| Fetterer, R | 1 |
| Bennett, JL | 1 |
| Clineschmidt, BV | 1 |
| McGuffin, JC | 1 |
| Tseng, LF | 2 |
| Cortés, A | 1 |
| Merino, G | 1 |
| Contreras, E | 1 |
| Cohen, ML | 1 |
| Wiley, KS | 1 |
| Fone, KC | 1 |
| Robinson, AJ | 1 |
| Marsden, CA | 1 |
| Burket, RC | 1 |
| Hodgin, JD | 1 |
| Leedham, JA | 1 |
| Foley, AJ | 1 |
| Pennefather, JN | 1 |
| Adler-Graschinsky, E | 1 |
| Butta, NV | 1 |
| Elgoyhen, AB | 1 |
1 trial available for fluoxetine and Muscle Contraction
| Article | Year |
|---|---|
Selective serotonin reuptake inhibitors: Their effect on high-intensity exercise performance.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Double-Blind Method; Exercise Test; Fluoxetine; Hum | 2001 |
36 other studies available for fluoxetine and Muscle Contraction
| Article | Year |
|---|---|
TAS-303 Ameliorates Carbachol-Induced Detrusor Overactivity in Rats, Revealing Its Therapeutic Potential for Overactive Bladder.
Topics: Adrenergic beta-3 Receptor Antagonists; Animals; Atropine; Carbachol; Dose-Response Relationship, Dr | 2020 |
Does fish oil or folic acid prevent vascular changes in female progeny caused by maternal exposure to fluoxetine?
Topics: Animals; Antidepressive Agents, Second-Generation; Blood Vessels; Female; Fish Oils; Fluoxetine; Fol | 2016 |
Signal Transduction Underlying the Inhibitory Mechanism of Fluoxetine on Electrical Field Stimulation Response in Rat Ileal Smooth Muscle.
Topics: 4-Aminopyridine; Amides; Animals; Atropine; Azepines; Benzophenanthridines; Bicuculline; Calcimycin; | 2017 |
Evaluating the role of the serotoninergic system in the control of human seminal vesicle smooth muscle-an in vitro approach.
Topics: Adrenergic alpha-Agonists; Aged; Clomipramine; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, D | 2009 |
Effects of long-term treatment with fluoxetine and venlafaxine on rat isolated vas deferens.
Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Second-Generation; Cyclohexanols; Electric S | 2010 |
The effect of fluoxetine on electrical field stimulation-induced responses in the isolated rat small intestine.
Topics: Adrenergic Uptake Inhibitors; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Fluox | 2010 |
Ferulic acid-induced anti-depression and prokinetics similar to Chaihu-Shugan-San via polypharmacology.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generatio | 2011 |
Effect of progesterone on colonic motility and fecal output in mice with diarrhea.
Topics: Animals; Colon; Defecation; Diarrhea; Enzyme-Linked Immunosorbent Assay; Fluoxetine; Gastrointestina | 2012 |
Effects of amitriptyline, fluoxetine, tranylcypromine and venlafaxine on rat vascular smooth muscle in vitro--the role of the endothelium.
Topics: Amitriptyline; Animals; Antidepressive Agents; Aorta, Abdominal; Aorta, Thoracic; Cyclic AMP; Cyclic | 2012 |
Changes of cytosolic calcium and contractility of young rat vas deferens by acute treatment with amphetamine, fluoxetine or sibutramine.
Topics: Amphetamine; Animals; Calcium; Central Nervous System Agents; Cyclobutanes; Cytosol; Fluoxetine; Hom | 2012 |
Serotonin and cholecystokinin mediate nutrient-induced segmentation in guinea pig small intestine.
Topics: Animals; Cholecystokinin; Decanoic Acids; Enteric Nervous System; Fatty Acids; Female; Fluoxetine; G | 2013 |
Calcium channel blocking activity of thioridazine, clomipramine and fluoxetine in isolated rat vas deferens: a relative potency measurement study.
Topics: Animals; Antidepressive Agents; Calcium; Calcium Channel Blockers; Clomipramine; Dose-Response Relat | 2002 |
Serotonin in the rabbit ileum: localization, uptake, and effect on motility.
Topics: Animals; Dose-Response Relationship, Drug; Female; Fluoxetine; Free Radical Scavengers; Gastrointest | 2003 |
Effects of the selective serotonin reuptake inhibitor, fluoxetine, on regional gastric contractility.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Drug Interactions; Fluoxetine; Gastric Fundus; Guin | 2005 |
Fluoxetine-resistance genes in Caenorhabditis elegans function in the intestine and may act in drug transport.
Topics: Amino Acid Sequence; Animals; Biological Transport, Active; Caenorhabditis elegans; Caenorhabditis e | 2006 |
Decreased noradrenergic and serotonergic reactivity of vas deferens of newborn rats from mothers treated with the serotonin reuptake inhibitor fluoxetine during pregnancy and breast-feeding.
Topics: Animals; Animals, Newborn; Barium; Birth Weight; Calcium; Dose-Response Relationship, Drug; Electric | 2007 |
Evidence for catecholamine-depleting action of fluoxetine.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Male; Muscle Contraction; | 1994 |
Facilitatory and inhibitory effects of selective norepinephrine reuptake inhibitors on hypogastric nerve-evoked urethral contractions in the cat: a prominent role of urethral beta-adrenergic receptors.
Topics: Animals; Atomoxetine Hydrochloride; Cats; Dose-Response Relationship, Drug; Female; Fluoxetine; Musc | 1994 |
Priapism of the clitoris: a case report following trazodone use.
Topics: Adjustment Disorders; Adult; Clitoris; Depression; Female; Fluoxetine; Humans; Muscle Contraction; M | 1993 |
Long-term treatment with fluoxetine associates with peripheral effects on rat vas deferens contractility.
Topics: Adrenergic Agents; Animals; Antidepressive Agents, Second-Generation; Binding Sites; Calcium; Cycloo | 1999 |
Assessment of the adrenergic effects of orphenadrine in rat vas deferens.
Topics: Adrenergic Agents; Animals; Atropine; Binding, Competitive; Dose-Response Relationship, Drug; Drug I | 1999 |
Fluoxetine modulates norepinephrine contractile effect on rat vas deferens.
Topics: Animals; Calcium; Cocaine; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; In Vitro Techn | 2000 |
Effects of antidepressants in adrenergic neurotransmission of human vas deferens.
Topics: Amitriptyline; Antidepressive Agents; Calcium; Calcium Channel Blockers; Culture Techniques; Dose-Re | 2000 |
Inhibitory effect of serotonergic drugs on contractile response of the rat vas deferens to electrical nerve stimulation: in vivo study.
Topics: Animals; Clomipramine; Electric Stimulation; Fluoxetine; Male; Muscle Contraction; Muscle, Smooth; P | 2000 |
Influence of castration on the response of the rat vas deferens to fluoxetine.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Castration; Cocaine; Dose-Response Relationship, Dru | 2000 |
Comparison of peripheral inhibitory effects of clomipramine with selective serotonin re-uptake inhibitors on contraction of vas deferens: in vitro and in vivo studies.
Topics: Adult; Antidepressive Agents, Tricyclic; Clomipramine; Dose-Response Relationship, Drug; Electric St | 2001 |
Effects of fluoxetine and imipramine on male Schistosoma mansoni.
Topics: Animals; Benzodiazepinones; Calcium; Drug Interactions; Fluoxetine; Imipramine; Lanthanum; Male; Mus | 1979 |
Pharmacological differentiation of the central 5-hydroxytryptamine-like actions of MK-212 (6-chloro-2[1-piperazinyl]-pyrazine),p-methoxyamphetamine and fenfluramine in an in vivo model system.
Topics: Amphetamines; Animals; Dextroamphetamine; Drug Interactions; Fenclonine; Fenfluramine; Fluoxetine; I | 1978 |
Blockade of para-methoxyamphetamine induced serotonin release by serotonin uptake inhibitors.
Topics: Amphetamines; Animals; Brain; Clomipramine; Desipramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; | 1978 |
Effect of fluoxetine (Lilly II0I40) on serotonin, noradrenaline and acetylcholine in isolated organs.
Topics: Acetylcholine; Animals; Female; Fluoxetine; Heart Atria; Intestine, Small; Male; Muscle Contraction; | 1978 |
Hydroxytryptamine uptake inhibitors block para- methoxyamphetamine-induced 5-HT release.
Topics: Amphetamines; Animals; Clomipramine; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Male | 1979 |
Neuronal uptake inhibitors, nisoxetine and fluoxetine on rat vascular contractions.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Drug Interactions; Electric Stimulation; Fluoxetine; In Vit | 1977 |
Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Clorgyline; Fluoxetine; Injections, S | 1991 |
Fluoxetine treatment of a depressed patient susceptible to malignant hyperthermia.
Topics: Adolescent; Caffeine; Depressive Disorder; Disease Susceptibility; Female; Fluoxetine; Halothane; Hu | 1989 |
Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake.
Topics: Animals; Bradykinin; Carbachol; Desipramine; Fluoxetine; Guinea Pigs; Histamine; In Vitro Techniques | 1985 |
Serotonin uptake inhibitors and the prejunctional effects of serotonin on peripheral sympathetic nerves.
Topics: Animals; Atropine; Biological Transport, Active; Cats; Citalopram; Fluoxetine; Guinea Pigs; Heart At | 1986 |