Page last updated: 2024-10-27

fluoxetine and Macular Degeneration

fluoxetine has been researched along with Macular Degeneration in 2 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Macular Degeneration: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Research Excerpts

ExcerptRelevanceReference
" Survival analysis was performed using Cox proportional hazards regression models and visualized using Kaplan Meier survival curves, with the following covariates-sex, ethnicity, smoking history, fluoxetine use, obesity, diabetes mellitus, and hypertension."4.31Effect of statins on the age of onset of age-related macular degeneration. ( Chiang, JN; Corradetti, G; Ganesh, D; Halperin, E; Sadda, SR; Zaitlen, N, 2023)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Ambati, M1
Apicella, I1
Wang, SB1
Narendran, S1
Leung, H1
Pereira, F1
Nagasaka, Y1
Huang, P1
Varshney, A1
Baker, KL1
Marion, KM1
Shadmehr, M1
Stains, CI1
Werner, BC1
Sadda, SR2
Taylor, EW1
Sutton, SS1
Magagnoli, J1
Gelfand, BD1
Ganesh, D1
Chiang, JN1
Corradetti, G1
Zaitlen, N1
Halperin, E1

Other Studies

2 other studies available for fluoxetine and Macular Degeneration

ArticleYear
Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 10-12, Volume: 118, Issue:41

    Topics: Alu Elements; Animals; Antidepressive Agents, Second-Generation; Blindness; Cell Line; Cytokines; De

2021
Effect of statins on the age of onset of age-related macular degeneration.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023, Volume: 261, Issue:8

    Topics: Age of Onset; Female; Fluoxetine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macular De

2023