fluoxetine has been researched along with Leukemia in 3 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report that the SSRI fluoxetine and the NSRI maprotiline are potent antiproliferative agents against human Burkitt lymphoma (BL), having little effect on normal blood cells." | 7.76 | The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters. ( Cloonan, SM; Drozgowska, A; Fayne, D; Williams, DC, 2010) |
| " We report that the SSRI fluoxetine and the NSRI maprotiline are potent antiproliferative agents against human Burkitt lymphoma (BL), having little effect on normal blood cells." | 3.76 | The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters. ( Cloonan, SM; Drozgowska, A; Fayne, D; Williams, DC, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cloonan, SM | 1 |
| Drozgowska, A | 1 |
| Fayne, D | 1 |
| Williams, DC | 1 |
| Weber, CC | 1 |
| Kressmann, S | 1 |
| Fricker, G | 1 |
| Müller, WE | 1 |
| Gordon, J | 1 |
| Barnes, N | 1 |
| Meredith, E | 1 |
| Drayson, M | 1 |
3 other studies available for fluoxetine and Leukemia
| Article | Year |
|---|---|
The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters.
Topics: Animals; Antidepressive Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; D | 2010 |
Modulation of P-glycoprotein function by St John's wort extract and its major constituents.
Topics: Adenosine Triphosphate; Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transpor | 2004 |
In response to "Selective serotonin reuptake inhibitors--a new modality for the treatment of lymphoma/leukaemia?" by C. Schuster, et al. [Biochem. Pharmacol. 74 (9) 2007 1424-1435].
Topics: Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Fluoxetine; Humans; Leukemia; | 2008 |