fluoxetine has been researched along with Irritable Bowel Syndrome in 5 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the effects of fluoxetine and placebo in the treatment of pain and constipation-predominant irritable bowel syndrome in a double-blind randomized-controlled trial." | 9.11 | The effect of fluoxetine in patients with pain and constipation-predominant irritable bowel syndrome: a double-blind randomized-controlled study. ( Ghoddoosi, A; Malekzadeh, R; Merat, S; Rashidioon, A; Vahedi, H, 2005) |
| " Fluoxetine did not significantly alter the threshold for discomfort/pain relative to placebo, either in hypersensitive (19 +/- 3 vs." | 9.10 | The selective serotonin reuptake inhibitor fluoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: a double blind, randomized, placebo-controlled study. ( Boeckxstaens, GE; Kuiken, SD; Tytgat, GN, 2003) |
| "To compare the effects of fluoxetine and placebo in the treatment of pain and constipation-predominant irritable bowel syndrome in a double-blind randomized-controlled trial." | 5.11 | The effect of fluoxetine in patients with pain and constipation-predominant irritable bowel syndrome: a double-blind randomized-controlled study. ( Ghoddoosi, A; Malekzadeh, R; Merat, S; Rashidioon, A; Vahedi, H, 2005) |
| " Fluoxetine did not significantly alter the threshold for discomfort/pain relative to placebo, either in hypersensitive (19 +/- 3 vs." | 5.10 | The selective serotonin reuptake inhibitor fluoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: a double blind, randomized, placebo-controlled study. ( Boeckxstaens, GE; Kuiken, SD; Tytgat, GN, 2003) |
| "Fluoxetine treatment increased 5-HT(4) receptor expression (0." | 1.38 | Effect of the 5-HT4 receptor and serotonin transporter on visceral hypersensitivity in rats. ( Hua-Hong, W; Jun-Xia, L; Xin-Guang, L; Yan, C; Yi-Xuan, L, 2012) |
| "A self-control and follow-up study on subclinical dosage of antidepressants therapy (fluoxetine 10 mg/d, paroxetine 10 mg/d or doxepin 45 mg/d) for 9-12 wks in 46 patients with refractory IBS symptoms according to Rome II criteria was performed, the clinical outcomes were evaluated by scales changes of symptom-related-anxiety, severity index of symptom, and quality of life specific of IBS, as well as general psychiatric health by SCL-90 during treatment and follow-up periods." | 1.32 | [Treatment of refractory irritable bowel syndrome with subclinical dosage of antidepressants]. ( Pan, GZ; Qian, JM; Wang, WA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bundeff, AW | 1 |
| Woodis, CB | 1 |
| Yan, C | 1 |
| Xin-Guang, L | 1 |
| Hua-Hong, W | 1 |
| Jun-Xia, L | 1 |
| Yi-Xuan, L | 1 |
| Wang, WA | 1 |
| Qian, JM | 1 |
| Pan, GZ | 1 |
| Kuiken, SD | 1 |
| Tytgat, GN | 1 |
| Boeckxstaens, GE | 1 |
| Vahedi, H | 1 |
| Merat, S | 1 |
| Rashidioon, A | 1 |
| Ghoddoosi, A | 1 |
| Malekzadeh, R | 1 |
1 review available for fluoxetine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Selective serotonin reuptake inhibitors for the treatment of irritable bowel syndrome.
Topics: Citalopram; Fluoxetine; Humans; Irritable Bowel Syndrome; Paroxetine; Randomized Controlled Trials a | 2014 |
2 trials available for fluoxetine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
The selective serotonin reuptake inhibitor fluoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: a double blind, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Double-Blind Method; Female; Fluoxetine | 2003 |
The effect of fluoxetine in patients with pain and constipation-predominant irritable bowel syndrome: a double-blind randomized-controlled study.
Topics: Abdominal Pain; Adult; Constipation; Double-Blind Method; Female; Fluoxetine; Humans; Irritable Bowe | 2005 |
2 other studies available for fluoxetine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Effect of the 5-HT4 receptor and serotonin transporter on visceral hypersensitivity in rats.
Topics: Animals; Animals, Newborn; Blotting, Western; Chronic Disease; Disease Models, Animal; Enzyme-Linked | 2012 |
[Treatment of refractory irritable bowel syndrome with subclinical dosage of antidepressants].
Topics: Adult; Antidepressive Agents; Doxepin; Female; Fluoxetine; Follow-Up Studies; Humans; Irritable Bowe | 2003 |