Page last updated: 2024-10-27

fluoxetine and Insulin Resistance

fluoxetine has been researched along with Insulin Resistance in 8 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"This study evaluates the effect of fluoxetine (FXTN) on insulin resistance and glucose uptake by various tissues in 90% pancreatectomized (Px) and sham-operated (Sham) rats."7.71Does fluoxetine administration influence insulin resistance in 90% pancreatectomized rats? ( Choi, SB; Park, S, 2002)
"Fluoxetine, a serotonin re-uptake inhibitor with antidepressive and appetite reduction effects, could improve insulin sensitivity."7.69[The effect of fluoxetine on insulin resistance in non diabetic obese patients]. ( Aguirre, C; Araya, V; Contreras, P; Depix, MS; Zura, ML, 1995)
" Following maprotiline treatment, the body weight and BMI were significantly increased (P=0."5.12Comparisons of glucose-insulin homeostasis following maprotiline and fluoxetine treatment in depressed males. ( Chen, YC; Chou, CH; Hung, YJ; Perng, CH; Shen, YC; Yeh, CB, 2007)
"This study evaluates the effect of fluoxetine (FXTN) on insulin resistance and glucose uptake by various tissues in 90% pancreatectomized (Px) and sham-operated (Sham) rats."3.71Does fluoxetine administration influence insulin resistance in 90% pancreatectomized rats? ( Choi, SB; Park, S, 2002)
"Fluoxetine, a serotonin re-uptake inhibitor with antidepressive and appetite reduction effects, could improve insulin sensitivity."3.69[The effect of fluoxetine on insulin resistance in non diabetic obese patients]. ( Aguirre, C; Araya, V; Contreras, P; Depix, MS; Zura, ML, 1995)
"Body weight was kept constant."2.67Fluoxetine increases insulin action in obese type II (non-insulin dependent) diabetic patients. ( Frölich, M; Krans, HM; Meinders, AE; Potter van Loon, BJ; Radder, JK; Zwinderman, AH, 1992)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, W1
Wang, Y1
Li, H1
Ji, L1
Pan, Y1
Hong, Y1
Zhang, QY1
Kong, LD1
Isaac, R1
Boura-Halfon, S1
Gurevitch, D1
Shainskaya, A1
Levkovitz, Y1
Zick, Y1
Chen, YC1
Shen, YC1
Hung, YJ1
Chou, CH1
Yeh, CB1
Perng, CH1
Araya, V1
Contreras, P1
Aguirre, C1
Depix, MS1
Zura, ML1
Park, S1
Choi, SB1
Potter van Loon, BJ1
Radder, JK1
Frölich, M1
Krans, HM1
Zwinderman, AH1
Meinders, AE1

Trials

2 trials available for fluoxetine and Insulin Resistance

ArticleYear
Comparisons of glucose-insulin homeostasis following maprotiline and fluoxetine treatment in depressed males.
    Journal of affective disorders, 2007, Volume: 103, Issue:1-3

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Second-Generation; Blood Glucose; Body M

2007
Fluoxetine increases insulin action in obese type II (non-insulin dependent) diabetic patients.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1992, Volume: 16 Suppl 4

    Topics: Blood Glucose; Body Weight; Diabetes Mellitus; Double-Blind Method; Female; Fluoxetine; Glucose; Glu

1992

Other Studies

6 other studies available for fluoxetine and Insulin Resistance

ArticleYear
In This Issue of
    Diabetes, 2019, Volume: 68, Issue:7

    Topics: Adipose Tissue; Animals; Cell Membrane; Diabetes Mellitus, Type 2; Diabetic Foot; Fluoxetine; Glucos

2019
The Role of Nitric Oxide in the Antidepressant Actions of 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside in Insulin-Resistant Mice.
    Psychosomatic medicine, 2016, Volume: 78, Issue:1

    Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Antidepressive Agents; Combined Modality Ther

2016
Impaired hypothalamic insulin signaling in CUMS rats: restored by icariin and fluoxetine through inhibiting CRF system.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:1

    Topics: Anhedonia; Animals; Antidepressive Agents; Arcuate Nucleus of Hypothalamus; Chronic Disease; Cortico

2013
Selective serotonin reuptake inhibitors (SSRIs) inhibit insulin secretion and action in pancreatic β cells.
    The Journal of biological chemistry, 2013, Feb-22, Volume: 288, Issue:8

    Topics: Animals; Apoptosis; Cell Death; Cell Line; Diabetes Mellitus; Fluoxetine; Humans; Insulin; Insulin R

2013
[The effect of fluoxetine on insulin resistance in non diabetic obese patients].
    Revista medica de Chile, 1995, Volume: 123, Issue:8

    Topics: Adult; Antidepressive Agents, Second-Generation; Fluoxetine; Glucose Tolerance Test; Humans; Insulin

1995
Does fluoxetine administration influence insulin resistance in 90% pancreatectomized rats?
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:1

    Topics: Animals; Deoxyglucose; Fluoxetine; Glucose; Glycogen; Insulin; Insulin Resistance; Liver; Male; Musc

2002