fluoxetine has been researched along with Innate Inflammatory Response in 66 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Depression could result from changes in tryptophan availability caused by activation of the kynurenine pathway as a result of inflammation." | 9.14 | Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling. ( Bridel, MA; Christofides, J; Cowlard, R; Darlington, LG; Forrest, CM; Mackay, GM; Mitchell, S; Stone, TW, 2009) |
| " We tested the effects of the SSRI fluoxetine on IgE-induced function of mast cells, which are critical effectors of allergic inflammation." | 8.31 | Fluoxetine restrains allergic inflammation by targeting an FcɛRI-ATP positive feedback loop in mast cells. ( Blakely, RD; Chalfant, CE; Chumanevich, AP; Dailey, JM; Fukuoka, Y; Gajewski-Kurdziel, PA; Haque, TT; Jackson, KG; Kankaria, R; Kee, SA; MacKnight, HP; Martin, RK; Oskeritzian, CA; Pondicherry, N; Ryan, JJ; Schwartz, LB; Stephenson, DJ; Straus, DB; Taruselli, MT; Zellner, MP, 2023) |
| " This study aimed to evaluate the anti-depressant effect of Cerebrolysin (CBL) in Reserpine-induced depressed rats, its effect on oxidative stress, inflammation, regulatory cyclic AMP-dependent response element binding protein (CREB)/brain derived neurotropic factor (BDNF) signaling pathways, brain monoamines and histopathological changes was assessed." | 8.02 | Anti-depressant effect of cerebrolysin in reserpine-induced depression in rats: Behavioral, biochemical, molecular and immunohistochemical evidence. ( Ahmed-Farid, OA; El Awdan, SA; El-Marasy, SA; Hassan, A; Ogaly, HA, 2021) |
| "Fluoxetine is commonly prescribed during pregnancy but developmental exposure to the drug, like infection, is associated with sex-specific behavioral changes in the offspring." | 8.02 | Short communication: Ex-vivo effects of fluoxetine on production of biomarkers for inflammation and neurodevelopment by the placenta. ( Ahmed, S; Arita, Y; Clementelli, C; Jeong Park, H; Levenson, AS; Peltier, MR; Pijush, DB, 2021) |
| " The influences of N-acetylcysteine (NAC) on neuroinflammation associated depression-like behavior have not been investigated yet, and associated biochemical changes are currently unclear." | 7.91 | N-acetylcysteine attenuates neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat. ( Fernandes, J; Gupta, GL, 2019) |
| "The study was designed to find out the effect of thymoquinone (TQ) alone and combination of TQ + fluoxetine in depression of type-2 diabetic rats." | 7.91 | Thymoquinone and fluoxetine alleviate depression via attenuating oxidative damage and inflammatory markers in type-2 diabetic rats. ( Alam, MF; Anwer, T; Khan, G; Masmali, AUM; Qumayri, HM; Safhi, MM; Siddiqui, R, 2019) |
| "The present study was undertaken to examine whether brexpiprazole could augment antidepressant effects of the SSRI fluoxetine in an inflammation model of depression." | 7.85 | Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation. ( Dong, C; Futamura, T; Hashimoto, K; Ma, M; Ohgi, Y; Ren, Q; Yang, C; Yao, W; Zhang, JC, 2017) |
| " 1-MT and fluoxetine were able to reverse the BCG-induced depression-like behavior and the derangement in oxidative stress parameters." | 7.83 | Comparison of fluoxetine and 1-methyl-L-tryptophan in treatment of depression-like illness in Bacillus Calmette-Guerin-induced inflammatory model of depression in mice. ( Banerjee, BD; Bhattacharya, SK; Deshmukh, P; Jain, S; Mediratta, PK; Rana, P; Sharma, AK, 2016) |
| " The aim of the present study was to investigate the involvement of OPN in fluoxetine amelioration of monocrotaline (MCT)-induced pulmonary inflammation and vascular remodelling in rats." | 7.77 | Downregulation of osteopontin is associated with fluoxetine amelioration of monocrotaline-induced pulmonary inflammation and vascular remodelling. ( Han, DD; Liu, M; Wang, HL; Wang, HM; Wang, Y; Zhang, XH, 2011) |
| "To investigate the effects of the selective serotonin reuptake inhibitor (SSRI) fluoxetine on extracellular matrix (ECM) remodeling of the pulmonary artery and inflammation of the lungs in pulmonary arterial hypertension (PAH) induced by monocrotaline in rats." | 7.77 | Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats. ( Han, DD; Li, XQ; Wang, HL; Wang, HM; Yang, CG; Zhang, XH, 2011) |
| "The GABA amides of the antidepressants nortriptyline and fluoxetine, 1 and 2, were compared to their respective parent compounds in rodent models of pain." | 7.75 | Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity. ( Aharoni, A; Geffen, Y; Gil-Ad, I; Halbfinger, E; Nisemblat, Y; Nudelman, A; Rephaeli, A; Tarasenko, I; Tarasenko, N; Weizman, A, 2009) |
| "The acute effect of the non-tricyclic, pro-serotoninergic, antidepressant drug fluoxetine on inflammatory edema was evaluated in the rat." | 7.69 | Fluoxetine reduces inflammatory edema in the rat: involvement of the pituitary-adrenal axis. ( Bianchi, M; Panerai, AE; Sacerdote, P, 1994) |
| "Depression is a common affective disorder or mood disorder, which seriously affects people's physical and mental health and the quality of life." | 6.87 | Analysis of curative effect of fluoxetine and escitalopram in the depression treatment based on clinical observation. ( Xiaoling, Z; Yingdong, L; Yunping, H, 2018) |
| "SRI use during pregnancy is associated with preterm premature rupture of membranes (PPROM) and subsequent preterm birth." | 5.91 | The serotonin reuptake inhibitor fluoxetine induces human fetal membrane sterile inflammation through p38 MAPK activation. ( Abrahams, VM; Fabrizio, VA; Hong, S; Lindsay, CV; Lynn, T; Norwitz, ER; Wilcox, M; Yonkers, KA, 2023) |
| "Fluoxetine and PLX3397 were administered." | 5.72 | Fluoxetine protects against inflammation and promotes autophagy in mice model of post-traumatic stress disorder. ( Amin, N; Chen, Y; Fang, M; Fang, Z; Lou, C; Ye, S, 2022) |
| "Fluoxetine resulted in a faster reduction of patients' inflammation without association with depression and anxiety." | 5.69 | Efficacy and safety of adding fluoxetine to the treatment regimen of hospitalized patients with non-critical COVID-19 pneumonia: A double-blind randomized, placebo-controlled clinical trial. ( Ala, S; Alizadeh Arimi, F; Elyasi, F; Ghasemian, R; Mehravaran, H; Moosazadeh, M; Sedighi, F; Zarghami, M, 2023) |
| "Inflammation has been associated with the progression of many neurological diseases." | 5.56 | Inflammation-induced behavioral changes is driven by alterations in Nrf2-dependent apoptosis and autophagy in mouse hippocampus: Role of fluoxetine. ( Adhikary, A; Chattopadhyay, S; Choudhury, S; Chowdhury, O; Das, A; Ghosh, S; Gupta, P; Mukherjee, S; Sain, A, 2020) |
| "The fluoxetine-induced rats were concurrently treated with olive oil or leaf extract." | 5.48 | Olive oil and leaf extract prevent fluoxetine-induced hepatotoxicity by attenuating oxidative stress, inflammation and apoptosis. ( Al Hroob, AM; Allach, M; El-Ghorab, AH; El-Massry, KF; Elgebaly, HA; Mahmoud, AM; Mosa, NM, 2018) |
| " Chronic administration of corticosterone (CORT) to rodents is used to mimic the stress associated dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, a well-established feature found in depressive patients." | 5.48 | Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. ( Js, IC; Kv, A; Lahkar, M; Madhana, RM; Naidu, VGM; Sinha, S, 2018) |
| "Fluoxetine is a selective serotonin (5-HT) reuptake inhibitor antidepressant." | 5.46 | Effects of fluoxetine on changes of pain sensitivity in chronic stress model rats. ( Chang, JL; Lian, YN; Lu, Q; Wang, Y; Zhang, FM; Zhang, Y, 2017) |
| " Depression could result from changes in tryptophan availability caused by activation of the kynurenine pathway as a result of inflammation." | 5.14 | Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling. ( Bridel, MA; Christofides, J; Cowlard, R; Darlington, LG; Forrest, CM; Mackay, GM; Mitchell, S; Stone, TW, 2009) |
| " We tested the effects of the SSRI fluoxetine on IgE-induced function of mast cells, which are critical effectors of allergic inflammation." | 4.31 | Fluoxetine restrains allergic inflammation by targeting an FcɛRI-ATP positive feedback loop in mast cells. ( Blakely, RD; Chalfant, CE; Chumanevich, AP; Dailey, JM; Fukuoka, Y; Gajewski-Kurdziel, PA; Haque, TT; Jackson, KG; Kankaria, R; Kee, SA; MacKnight, HP; Martin, RK; Oskeritzian, CA; Pondicherry, N; Ryan, JJ; Schwartz, LB; Stephenson, DJ; Straus, DB; Taruselli, MT; Zellner, MP, 2023) |
| "Fluoxetine is commonly prescribed during pregnancy but developmental exposure to the drug, like infection, is associated with sex-specific behavioral changes in the offspring." | 4.02 | Short communication: Ex-vivo effects of fluoxetine on production of biomarkers for inflammation and neurodevelopment by the placenta. ( Ahmed, S; Arita, Y; Clementelli, C; Jeong Park, H; Levenson, AS; Peltier, MR; Pijush, DB, 2021) |
| " This study aimed to evaluate the anti-depressant effect of Cerebrolysin (CBL) in Reserpine-induced depressed rats, its effect on oxidative stress, inflammation, regulatory cyclic AMP-dependent response element binding protein (CREB)/brain derived neurotropic factor (BDNF) signaling pathways, brain monoamines and histopathological changes was assessed." | 4.02 | Anti-depressant effect of cerebrolysin in reserpine-induced depression in rats: Behavioral, biochemical, molecular and immunohistochemical evidence. ( Ahmed-Farid, OA; El Awdan, SA; El-Marasy, SA; Hassan, A; Ogaly, HA, 2021) |
| " The influences of N-acetylcysteine (NAC) on neuroinflammation associated depression-like behavior have not been investigated yet, and associated biochemical changes are currently unclear." | 3.91 | N-acetylcysteine attenuates neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat. ( Fernandes, J; Gupta, GL, 2019) |
| "The study was designed to find out the effect of thymoquinone (TQ) alone and combination of TQ + fluoxetine in depression of type-2 diabetic rats." | 3.91 | Thymoquinone and fluoxetine alleviate depression via attenuating oxidative damage and inflammatory markers in type-2 diabetic rats. ( Alam, MF; Anwer, T; Khan, G; Masmali, AUM; Qumayri, HM; Safhi, MM; Siddiqui, R, 2019) |
| "The present study was undertaken to examine whether brexpiprazole could augment antidepressant effects of the SSRI fluoxetine in an inflammation model of depression." | 3.85 | Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation. ( Dong, C; Futamura, T; Hashimoto, K; Ma, M; Ohgi, Y; Ren, Q; Yang, C; Yao, W; Zhang, JC, 2017) |
| " 1-MT and fluoxetine were able to reverse the BCG-induced depression-like behavior and the derangement in oxidative stress parameters." | 3.83 | Comparison of fluoxetine and 1-methyl-L-tryptophan in treatment of depression-like illness in Bacillus Calmette-Guerin-induced inflammatory model of depression in mice. ( Banerjee, BD; Bhattacharya, SK; Deshmukh, P; Jain, S; Mediratta, PK; Rana, P; Sharma, AK, 2016) |
| "This study was carried out to clarify the effects of the antidepressant fluoxetine, a selective serotonin reuptake inhibitor, for its potential use in autoimmune diseases like multiple sclerosis in a rat model of experimental autoimmune encephalomyelitis (EAE)." | 3.78 | Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats. ( Liu, S; Liu, XJ; Lu, T; Qiu, G; Wang, X; Wu, Y; Yuan, XQ, 2012) |
| "To investigate the effects of the selective serotonin reuptake inhibitor (SSRI) fluoxetine on extracellular matrix (ECM) remodeling of the pulmonary artery and inflammation of the lungs in pulmonary arterial hypertension (PAH) induced by monocrotaline in rats." | 3.77 | Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats. ( Han, DD; Li, XQ; Wang, HL; Wang, HM; Yang, CG; Zhang, XH, 2011) |
| " The aim of the present study was to investigate the involvement of OPN in fluoxetine amelioration of monocrotaline (MCT)-induced pulmonary inflammation and vascular remodelling in rats." | 3.77 | Downregulation of osteopontin is associated with fluoxetine amelioration of monocrotaline-induced pulmonary inflammation and vascular remodelling. ( Han, DD; Liu, M; Wang, HL; Wang, HM; Wang, Y; Zhang, XH, 2011) |
| " First, validate PEAP with Complete Freund's Adjuvant (CFA)-induced inflammation for the assessment of the affective component of pain using the reference analgesics celecoxib, diclofenac and duloxetine; fluoxetine and scopolamine were tested as negative controls." | 3.76 | Comparison of mechanical allodynia and the affective component of inflammatory pain in rats. ( Baker, SJ; Boyce-Rustay, JM; Decker, MW; Honore, P; Kohnken, R; Simler, GH; Wensink, EJ; Zhong, C, 2010) |
| "The GABA amides of the antidepressants nortriptyline and fluoxetine, 1 and 2, were compared to their respective parent compounds in rodent models of pain." | 3.75 | Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity. ( Aharoni, A; Geffen, Y; Gil-Ad, I; Halbfinger, E; Nisemblat, Y; Nudelman, A; Rephaeli, A; Tarasenko, I; Tarasenko, N; Weizman, A, 2009) |
| " The non-selective noradrenaline (NA) and serotonin (5-HT) reuptake inhibitors imipramine, amitriptyline and clomipramine displayed anti-inflammatory activity in the carrageenan model of paw inflammation." | 3.72 | Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat. ( Abdel-Salam, OM; El-Shenawy, SM; Nofal, SM, 2003) |
| "The anti-inflammatory activity of fluoxetine, a selective serotonin reuptake inhibitor (SSRI), was studied on the carrageenan-induced paw inflammation in the rat." | 3.72 | Studies on the anti-inflammatory effect of fluoxetine in the rat. ( Abdel-Salam, OM; Arbid, MS; Baiuomy, AR, 2004) |
| "The acute effect of the non-tricyclic, pro-serotoninergic, antidepressant drug fluoxetine on inflammatory edema was evaluated in the rat." | 3.69 | Fluoxetine reduces inflammatory edema in the rat: involvement of the pituitary-adrenal axis. ( Bianchi, M; Panerai, AE; Sacerdote, P, 1994) |
| "Depression is a common affective disorder or mood disorder, which seriously affects people's physical and mental health and the quality of life." | 2.87 | Analysis of curative effect of fluoxetine and escitalopram in the depression treatment based on clinical observation. ( Xiaoling, Z; Yingdong, L; Yunping, H, 2018) |
| "SRI use during pregnancy is associated with preterm premature rupture of membranes (PPROM) and subsequent preterm birth." | 1.91 | The serotonin reuptake inhibitor fluoxetine induces human fetal membrane sterile inflammation through p38 MAPK activation. ( Abrahams, VM; Fabrizio, VA; Hong, S; Lindsay, CV; Lynn, T; Norwitz, ER; Wilcox, M; Yonkers, KA, 2023) |
| "Traumatic brain injury was associated with an increase in intestinal permeability to FITC-dextran, increased lung vascular permeability, and worse performance on the rota-rod." | 1.72 | Fluoxetine reduces organ injury and improves motor function after traumatic brain injury in mice. ( Costantini, TW; Eliceiri, B; Weaver, JL, 2022) |
| "Fluoxetine and PLX3397 were administered." | 1.72 | Fluoxetine protects against inflammation and promotes autophagy in mice model of post-traumatic stress disorder. ( Amin, N; Chen, Y; Fang, M; Fang, Z; Lou, C; Ye, S, 2022) |
| "Fluoxetine group was administered with fluoxetine (2." | 1.72 | Anti-depressant effects of acupuncture: The insights from NLRP3 mediated pyroptosis and inflammation. ( Chen, W; Chen, Y; Cheng, W; Hao, C; He, T; Huang, S; Huang, Z; Li, P; Meng, X; Shen, J; Tong, T; Yan, S, 2022) |
| "Depression is a mental disease involving complex pathophysiological mechanisms, and there are many ways to establish depressive mouse models." | 1.72 | Comparison of LPS and MS-induced depressive mouse model: behavior, inflammation and biochemical changes. ( Dong, Y; Liu, L; Liu, S; Yao, H; Yu, X; Zhang, X, 2022) |
| "Fluoxetine (Fx) is an FDA-approved anti-depressant agent and one of the selective serotonin reuptake inhibitor drugs (SSRI), used in neurological disorder treatment." | 1.62 | Modulation of the Nitric Oxide/BH4 Pathway Protects Against Irradiation-Induced Neuronal Damage. ( Abdel-Rafei, MK; Moustafa, EM; Rashed, ER; Thabet, NM, 2021) |
| "Inflammation has been associated with the progression of many neurological diseases." | 1.56 | Inflammation-induced behavioral changes is driven by alterations in Nrf2-dependent apoptosis and autophagy in mouse hippocampus: Role of fluoxetine. ( Adhikary, A; Chattopadhyay, S; Choudhury, S; Chowdhury, O; Das, A; Ghosh, S; Gupta, P; Mukherjee, S; Sain, A, 2020) |
| "Depression is a mental disease that causes severe economic and social burdens." | 1.51 | Tauroursodeoxycholic Acid Ameliorates Lipopolysaccharide-Induced Depression Like Behavior in Mice via the Inhibition of Neuroinflammation and Oxido-Nitrosative Stress. ( Chen, Z; Cheng, L; Huang, C, 2019) |
| "However, depression with COPD comorbidity is often underdiagnosed and undertreated, and pathogenic research is also insufficient." | 1.51 | Glucocorticoid receptor dysfunction orchestrates inflammasome effects on chronic obstructive pulmonary disease-induced depression: A potential mechanism underlying the cross talk between lung and brain. ( Deng, X; Fu, J; Guo, Q; Ji, Z; Ma, S; Song, Y; Xu, B, 2019) |
| " Chronic administration of corticosterone (CORT) to rodents is used to mimic the stress associated dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, a well-established feature found in depressive patients." | 1.48 | Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. ( Js, IC; Kv, A; Lahkar, M; Madhana, RM; Naidu, VGM; Sinha, S, 2018) |
| "The fluoxetine-induced rats were concurrently treated with olive oil or leaf extract." | 1.48 | Olive oil and leaf extract prevent fluoxetine-induced hepatotoxicity by attenuating oxidative stress, inflammation and apoptosis. ( Al Hroob, AM; Allach, M; El-Ghorab, AH; El-Massry, KF; Elgebaly, HA; Mahmoud, AM; Mosa, NM, 2018) |
| "Fluoxetine is a selective serotonin (5-HT) reuptake inhibitor antidepressant." | 1.46 | Effects of fluoxetine on changes of pain sensitivity in chronic stress model rats. ( Chang, JL; Lian, YN; Lu, Q; Wang, Y; Zhang, FM; Zhang, Y, 2017) |
| "Fluoxetine treatment blocked stress-induced up-regulation of HMGB1 and subsequent NF-κB activation, whereas TDZD-8 administration attenuated NF-κB activation downstream of HMGB1." | 1.43 | Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior. ( Armini, RS; Beurel, E; Cheng, Y; Jope, RS; Martinez, A; Mouhsine, H; Pardo, M; Zagury, JF, 2016) |
| "Survival of lipopolysaccharide-induced endotoxic shock was improved in Tph1(-/-) mice." | 1.39 | Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice. ( Bader, M; Bode, C; Brill, A; Carbo, C; Cicko, S; Cifuni, SM; Demers, M; Duerschmied, D; Herr, N; Idzko, M; Mauler, M; Suidan, GL; Wagner, DD, 2013) |
| "Mechanical hyperalgesia was assessed after acute treatment with TAT-2ASCV or/and fluoxetine (SSRI) 2." | 1.39 | Disruption of 5-HT2A receptor-PDZ protein interactions alleviates mechanical hypersensitivity in carrageenan-induced inflammation in rats. ( Aissouni, Y; Chalus, M; Courteix, C; Dupuis, A; Eschalier, A; Hernández, A; Marin, P; Pelissier, T; Pichon, X; Privat, AM; Wattiez, AS, 2013) |
| "CD-1 mice were dosed with Bacille Calmette-Guérin (BCG) and measures of body weight, locomotor activity, and immobility in the tail suspension test (TST) were made." | 1.39 | A depressive phenotype induced by Bacille Calmette Guérin in 'susceptible' animals: sensitivity to antidepressants. ( Clark, JA; Klee, N; Nizami, M; Platt, B; Schulenberg, J, 2013) |
| " 10b was additionally bioavailable following oral dosing and demonstrated efficacy in rat models of acute, inflammatory, and neuropathic pain." | 1.37 | Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152). ( Adedoyin, A; Bray, JA; Deecher, DC; Fensome, A; Goldberg, JA; Harrison, J; Leventhal, L; Mann, C; Mark, L; Nogle, L; O'Neill, DJ; Spangler, TB; Sullivan, NR; Terefenko, EA; Trybulski, EJ; Uveges, AJ; Vu, A; Whiteside, GT; Zhang, P, 2011) |
| "In the septic shock model, all three drugs given preventively markedly decreased circulating levels of TNF-alpha and mortality (50% mortality in fluoxetine treated group, 30% in desipramine and prednisolone treated groups versus 90% in controls)." | 1.34 | Anti-inflammatory properties of desipramine and fluoxetine. ( Bichon, F; Detoc, M; Henriquet, C; Jaffuel, D; Mathieu, M; Michel, A; Portet, K; Roumestan, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.52) | 18.2507 |
| 2000's | 9 (13.64) | 29.6817 |
| 2010's | 36 (54.55) | 24.3611 |
| 2020's | 20 (30.30) | 2.80 |
| Authors | Studies |
|---|---|
| Rephaeli, A | 1 |
| Gil-Ad, I | 1 |
| Aharoni, A | 1 |
| Tarasenko, I | 1 |
| Tarasenko, N | 1 |
| Geffen, Y | 1 |
| Halbfinger, E | 1 |
| Nisemblat, Y | 1 |
| Weizman, A | 1 |
| Nudelman, A | 1 |
| O'Neill, DJ | 1 |
| Adedoyin, A | 1 |
| Bray, JA | 1 |
| Deecher, DC | 1 |
| Fensome, A | 1 |
| Goldberg, JA | 1 |
| Harrison, J | 1 |
| Leventhal, L | 1 |
| Mann, C | 1 |
| Mark, L | 1 |
| Nogle, L | 1 |
| Sullivan, NR | 1 |
| Spangler, TB | 1 |
| Terefenko, EA | 1 |
| Trybulski, EJ | 1 |
| Uveges, AJ | 1 |
| Vu, A | 1 |
| Whiteside, GT | 1 |
| Zhang, P | 1 |
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Huang, Z | 2 |
| Yin, L | 1 |
| Guan, L | 1 |
| Li, Z | 2 |
| Tan, C | 1 |
| Weaver, JL | 1 |
| Eliceiri, B | 1 |
| Costantini, TW | 1 |
| Lou, C | 1 |
| Fang, M | 1 |
| Ye, S | 1 |
| Fang, Z | 1 |
| Amin, N | 1 |
| Chen, Y | 2 |
| Hao, C | 1 |
| Chen, W | 2 |
| Cheng, W | 1 |
| Li, P | 1 |
| Shen, J | 1 |
| Tong, T | 1 |
| Yan, S | 1 |
| Huang, S | 1 |
| He, T | 1 |
| Meng, X | 1 |
| Jang, DY | 1 |
| Yang, B | 1 |
| You, MJ | 1 |
| Rim, C | 1 |
| Kim, HJ | 1 |
| Sung, S | 1 |
| Kwon, MS | 1 |
| Yu, X | 1 |
| Yao, H | 1 |
| Zhang, X | 2 |
| Liu, L | 1 |
| Liu, S | 2 |
| Dong, Y | 1 |
| Fabrizio, VA | 2 |
| Lindsay, CV | 2 |
| Wilcox, M | 2 |
| Hong, S | 2 |
| Lynn, T | 2 |
| Norwitz, ER | 2 |
| Yonkers, KA | 2 |
| Abrahams, VM | 2 |
| Mojiri-Forushani, H | 1 |
| Khajehali, E | 1 |
| Adelipour, M | 1 |
| Mohammadi, A | 1 |
| Sedighi, F | 1 |
| Zarghami, M | 1 |
| Alizadeh Arimi, F | 1 |
| Moosazadeh, M | 1 |
| Ala, S | 1 |
| Ghasemian, R | 1 |
| Mehravaran, H | 1 |
| Elyasi, F | 1 |
| Jin, H | 1 |
| Xu, G | 1 |
| Lu, Y | 1 |
| Niu, C | 1 |
| Kan, T | 1 |
| Cao, J | 1 |
| Yang, X | 1 |
| Cheng, Q | 1 |
| Zhang, J | 3 |
| Dong, J | 1 |
| Haque, TT | 1 |
| Taruselli, MT | 1 |
| Kee, SA | 1 |
| Dailey, JM | 1 |
| Pondicherry, N | 1 |
| Gajewski-Kurdziel, PA | 1 |
| Zellner, MP | 1 |
| Stephenson, DJ | 1 |
| MacKnight, HP | 1 |
| Straus, DB | 1 |
| Kankaria, R | 1 |
| Jackson, KG | 1 |
| Chumanevich, AP | 1 |
| Fukuoka, Y | 1 |
| Schwartz, LB | 1 |
| Blakely, RD | 1 |
| Oskeritzian, CA | 1 |
| Chalfant, CE | 1 |
| Martin, RK | 1 |
| Ryan, JJ | 1 |
| Prowse, KL | 1 |
| Law, H | 1 |
| Raez-Villanueva, S | 1 |
| Markovic, F | 1 |
| Wang, M | 1 |
| Borojevic, R | 1 |
| Parsons, SP | 1 |
| Vincent, AD | 1 |
| Holloway, AC | 1 |
| Ratcliffe, EM | 1 |
| Yuan, P | 1 |
| Li, L | 1 |
| Song, Z | 1 |
| Ghosh, S | 2 |
| Choudhury, S | 2 |
| Chowdhury, O | 2 |
| Mukherjee, S | 2 |
| Das, A | 1 |
| Sain, A | 1 |
| Gupta, P | 2 |
| Adhikary, A | 1 |
| Chattopadhyay, S | 2 |
| Zhang, K | 1 |
| Lin, W | 1 |
| Zhao, Y | 1 |
| Wang, X | 2 |
| Zhao, M | 1 |
| Lübow, C | 1 |
| Bockstiegel, J | 1 |
| Weindl, G | 1 |
| Butkevich, IP | 1 |
| Mikhailenko, VA | 1 |
| El-Marasy, SA | 2 |
| El Awdan, SA | 1 |
| Hassan, A | 1 |
| Ahmed-Farid, OA | 1 |
| Ogaly, HA | 1 |
| Thabet, NM | 1 |
| Rashed, ER | 1 |
| Abdel-Rafei, MK | 1 |
| Moustafa, EM | 1 |
| Clementelli, C | 1 |
| Arita, Y | 1 |
| Ahmed, S | 1 |
| Pijush, DB | 1 |
| Jeong Park, H | 1 |
| Levenson, AS | 1 |
| Peltier, MR | 1 |
| Qiu, W | 1 |
| Go, KA | 1 |
| Wen, Y | 1 |
| Duarte-Guterman, P | 1 |
| Eid, RS | 1 |
| Galea, LAM | 1 |
| Nowacka-Chmielewska, MM | 1 |
| Kasprowska, D | 1 |
| Paul-Samojedny, M | 1 |
| Bielecka-Wajdman, AM | 1 |
| Barski, JJ | 1 |
| Małecki, A | 1 |
| Obuchowicz, E | 1 |
| Lian, YN | 1 |
| Chang, JL | 1 |
| Lu, Q | 1 |
| Wang, Y | 3 |
| Zhang, Y | 1 |
| Zhang, FM | 1 |
| Elgebaly, HA | 1 |
| Mosa, NM | 1 |
| Allach, M | 1 |
| El-Massry, KF | 1 |
| El-Ghorab, AH | 1 |
| Al Hroob, AM | 1 |
| Mahmoud, AM | 1 |
| Kv, A | 1 |
| Madhana, RM | 1 |
| Js, IC | 1 |
| Lahkar, M | 1 |
| Sinha, S | 1 |
| Naidu, VGM | 1 |
| Safhi, MM | 1 |
| Qumayri, HM | 1 |
| Masmali, AUM | 1 |
| Siddiqui, R | 1 |
| Alam, MF | 1 |
| Khan, G | 1 |
| Anwer, T | 1 |
| Xiaoling, Z | 1 |
| Yunping, H | 1 |
| Yingdong, L | 1 |
| Song, Y | 2 |
| Sun, R | 1 |
| Ji, Z | 2 |
| Li, X | 1 |
| Fu, Q | 1 |
| Ma, S | 2 |
| Aguilar-Valles, A | 1 |
| Haji, N | 1 |
| De Gregorio, D | 1 |
| Matta-Camacho, E | 1 |
| Eslamizade, MJ | 1 |
| Popic, J | 1 |
| Sharma, V | 1 |
| Cao, R | 1 |
| Rummel, C | 1 |
| Tanti, A | 1 |
| Wiebe, S | 1 |
| Nuñez, N | 1 |
| Comai, S | 1 |
| Nadon, R | 1 |
| Luheshi, G | 1 |
| Mechawar, N | 1 |
| Turecki, G | 1 |
| Lacaille, JC | 1 |
| Gobbi, G | 1 |
| Sonenberg, N | 1 |
| Bansal, Y | 1 |
| Singh, R | 1 |
| Saroj, P | 1 |
| Sodhi, RK | 1 |
| Kuhad, A | 1 |
| Cheng, L | 1 |
| Huang, C | 1 |
| Chen, Z | 1 |
| Baral, R | 1 |
| Deng, X | 1 |
| Fu, J | 1 |
| Xu, B | 1 |
| Guo, Q | 1 |
| Fernandes, J | 1 |
| Gupta, GL | 1 |
| Ashraf, A | 1 |
| Mahmoud, PA | 1 |
| Reda, H | 1 |
| Mansour, S | 1 |
| Helal, MH | 1 |
| Michel, HE | 1 |
| Nasr, M | 1 |
| Tian, M | 1 |
| Yang, M | 1 |
| Yang, L | 1 |
| Li, Y | 1 |
| Yuan, H | 1 |
| Wattiez, AS | 1 |
| Pichon, X | 1 |
| Dupuis, A | 1 |
| Hernández, A | 1 |
| Privat, AM | 1 |
| Aissouni, Y | 1 |
| Chalus, M | 1 |
| Pelissier, T | 1 |
| Eschalier, A | 1 |
| Marin, P | 1 |
| Courteix, C | 1 |
| Pan, Y | 1 |
| Chen, XY | 1 |
| Zhang, QY | 1 |
| Kong, LD | 1 |
| Yang, JM | 1 |
| Rui, BB | 1 |
| Chen, C | 1 |
| Chen, H | 1 |
| Xu, TJ | 1 |
| Xu, WP | 1 |
| Wei, W | 1 |
| Abdallah, HM | 1 |
| El-Shenawy, SM | 2 |
| El-Khatib, AS | 1 |
| El-Shabrawy, OA | 1 |
| Kenawy, SA | 1 |
| Yun, HM | 1 |
| Park, KR | 1 |
| Kim, EC | 1 |
| Kim, S | 1 |
| Hong, JT | 1 |
| Yu, XB | 1 |
| Dong, RR | 1 |
| Wang, H | 1 |
| Lin, JR | 1 |
| An, YQ | 1 |
| Du, Y | 1 |
| Tang, SS | 1 |
| Hu, M | 1 |
| Long, Y | 1 |
| Sun, HB | 1 |
| Kong, LY | 1 |
| Hong, H | 1 |
| Cheng, Y | 1 |
| Pardo, M | 1 |
| Armini, RS | 1 |
| Martinez, A | 1 |
| Mouhsine, H | 1 |
| Zagury, JF | 1 |
| Jope, RS | 1 |
| Beurel, E | 1 |
| Kao, CY | 1 |
| He, Z | 1 |
| Zannas, AS | 1 |
| Hahn, O | 1 |
| Kühne, C | 1 |
| Reichel, JM | 1 |
| Binder, EB | 1 |
| Wotjak, CT | 1 |
| Khaitovich, P | 1 |
| Turck, CW | 1 |
| Rana, P | 1 |
| Sharma, AK | 1 |
| Jain, S | 1 |
| Deshmukh, P | 1 |
| Bhattacharya, SK | 1 |
| Banerjee, BD | 1 |
| Mediratta, PK | 1 |
| Zhang, JC | 2 |
| Yao, W | 2 |
| Ren, Q | 2 |
| Yang, C | 2 |
| Dong, C | 2 |
| Ma, M | 2 |
| Wu, J | 1 |
| Hashimoto, K | 2 |
| Ohgi, Y | 1 |
| Futamura, T | 1 |
| Mackay, GM | 1 |
| Forrest, CM | 1 |
| Christofides, J | 1 |
| Bridel, MA | 1 |
| Mitchell, S | 1 |
| Cowlard, R | 1 |
| Stone, TW | 1 |
| Darlington, LG | 1 |
| Boyce-Rustay, JM | 1 |
| Zhong, C | 1 |
| Kohnken, R | 1 |
| Baker, SJ | 1 |
| Simler, GH | 1 |
| Wensink, EJ | 1 |
| Decker, MW | 1 |
| Honore, P | 1 |
| Li, XQ | 1 |
| Wang, HM | 2 |
| Yang, CG | 1 |
| Zhang, XH | 2 |
| Han, DD | 2 |
| Wang, HL | 2 |
| Liu, M | 1 |
| Yuan, XQ | 1 |
| Qiu, G | 1 |
| Liu, XJ | 1 |
| Wu, Y | 1 |
| Lu, T | 1 |
| Platt, B | 1 |
| Schulenberg, J | 1 |
| Klee, N | 1 |
| Nizami, M | 1 |
| Clark, JA | 1 |
| Ledo, JH | 1 |
| Azevedo, EP | 1 |
| Clarke, JR | 1 |
| Ribeiro, FC | 1 |
| Figueiredo, CP | 1 |
| Foguel, D | 1 |
| De Felice, FG | 1 |
| Ferreira, ST | 1 |
| Duerschmied, D | 1 |
| Suidan, GL | 1 |
| Demers, M | 1 |
| Herr, N | 1 |
| Carbo, C | 1 |
| Brill, A | 1 |
| Cifuni, SM | 1 |
| Mauler, M | 1 |
| Cicko, S | 1 |
| Bader, M | 1 |
| Idzko, M | 1 |
| Bode, C | 1 |
| Wagner, DD | 1 |
| Abdel-Salam, OM | 2 |
| Nofal, SM | 1 |
| Baiuomy, AR | 1 |
| Arbid, MS | 1 |
| Kubera, M | 1 |
| Kenis, G | 1 |
| Bosmans, E | 1 |
| Kajta, M | 1 |
| Basta-Kaim, A | 1 |
| Scharpe, S | 1 |
| Budziszewska, B | 1 |
| Maes, M | 1 |
| Roumestan, C | 1 |
| Michel, A | 1 |
| Bichon, F | 1 |
| Portet, K | 1 |
| Detoc, M | 1 |
| Henriquet, C | 1 |
| Jaffuel, D | 1 |
| Mathieu, M | 1 |
| Mostert, JP | 1 |
| Admiraal-Behloul, F | 1 |
| Hoogduin, JM | 1 |
| Luyendijk, J | 1 |
| Heersema, DJ | 1 |
| van Buchem, MA | 1 |
| De Keyser, J | 1 |
| Bianchi, M | 1 |
| Sacerdote, P | 1 |
| Panerai, AE | 1 |
| McCleane, G | 1 |
| Fioramonti, J | 1 |
| Bueno, L | 1 |
| Delvaux, M | 1 |
| Frexinos, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Professor[NCT05138887] | Phase 2 | 366 participants (Anticipated) | Interventional | 2022-03-01 | Recruiting | ||
| A Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of a Weight Management Program on Body Weight in Individuals Who Are Overweight and Otherwise Healthy[NCT04107155] | 54 participants (Actual) | Interventional | 2019-07-23 | Completed | |||
| A Randomized Controlled Trial to Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain in Overweight But Generally Healthy Adults Over the Winter Holiday Period[NCT03372109] | 23 participants (Actual) | Interventional | 2017-11-14 | Completed | |||
| Fluoxetine to Reduce Hospitalization From COVID-19 Infection (FloR COVID-19)[NCT04570449] | Early Phase 1 | 0 participants (Actual) | Interventional | 2020-11-30 | Withdrawn (stopped due to Study timeline is not feasible) | ||
| 5-HTSEP: Serotonin 5-HT7 Receptor Implication in the Inflammatory Mechanisms in Multiple Sclerosis[NCT04546698] | 78 participants (Actual) | Observational | 2020-09-07 | Completed | |||
| RESEPTOR 5-HT7 : Interest of the 5-HT7 Serotonin Receptor as a Biomarker in Multiple Sclerosis[NCT05746845] | 120 participants (Anticipated) | Observational | 2023-03-06 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for fluoxetine and Innate Inflammatory Response
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
[Old and new physiopathological concepts of irritable bowel syndrome].
Topics: Adult; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agen | 2001 |
4 trials available for fluoxetine and Innate Inflammatory Response
| Article | Year |
|---|---|
Efficacy and safety of adding fluoxetine to the treatment regimen of hospitalized patients with non-critical COVID-19 pneumonia: A double-blind randomized, placebo-controlled clinical trial.
Topics: Antidepressive Agents, Second-Generation; Anxiety; C-Reactive Protein; COVID-19; Depression; Double- | 2023 |
Analysis of curative effect of fluoxetine and escitalopram in the depression treatment based on clinical observation.
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Cytokines; Depression; Female; Fluoxeti | 2018 |
Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling.
Topics: Adult; Antidepressive Agents; Biomarkers; Counseling; Depression; Drug Therapy, Combination; Female; | 2009 |
Effects of fluoxetine on disease activity in relapsing multiple sclerosis: a double-blind, placebo-controlled, exploratory study.
Topics: Adult; Brain; Double-Blind Method; Female; Fluoxetine; Humans; Inflammation; Magnetic Resonance Imag | 2008 |
60 other studies available for fluoxetine and Innate Inflammatory Response
| Article | Year |
|---|---|
Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity.
Topics: Analgesics; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Fluoxetine; Formaldehyde; gam | 2009 |
Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).
Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Benzothiazoles; Biological Availability; Cell | 2011 |
Novel piperazine-2,5-dione analogs bearing 1H-indole: Synthesis and biological effects.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Depression; Drug Discovery; In | 2020 |
Fluoxetine reduces organ injury and improves motor function after traumatic brain injury in mice.
Topics: Animals; Brain Injuries; Brain Injuries, Traumatic; Disease Models, Animal; Fluoxetine; Humans; Infl | 2022 |
Fluoxetine protects against inflammation and promotes autophagy in mice model of post-traumatic stress disorder.
Topics: Animals; Autophagy; Disease Models, Animal; Fluoxetine; Inflammation; Mice; Mice, Inbred C57BL; Stre | 2022 |
Anti-depressant effects of acupuncture: The insights from NLRP3 mediated pyroptosis and inflammation.
Topics: Acupuncture Therapy; Animals; Depression; Fluoxetine; Inflammasomes; Inflammation; NLR Family, Pyrin | 2022 |
Fluoxetine Decreases Phagocytic Function via REV-ERBα in Microglia.
Topics: ARNTL Transcription Factors; Circadian Rhythm; Depressive Disorder, Major; Fluoxetine; Humans; Infla | 2023 |
Comparison of LPS and MS-induced depressive mouse model: behavior, inflammation and biochemical changes.
Topics: Animals; Depression; Disease Models, Animal; Fluoxetine; Hippocampus; Humans; Hypothalamo-Hypophysea | 2022 |
The serotonin reuptake inhibitor fluoxetine induces human fetal membrane sterile inflammation through p38 MAPK activation.
Topics: Antidepressive Agents; Extraembryonic Membranes; Female; Fetal Membranes, Premature Rupture; Fluoxet | 2023 |
The serotonin reuptake inhibitor fluoxetine induces human fetal membrane sterile inflammation through p38 MAPK activation.
Topics: Antidepressive Agents; Extraembryonic Membranes; Female; Fetal Membranes, Premature Rupture; Fluoxet | 2023 |
The serotonin reuptake inhibitor fluoxetine induces human fetal membrane sterile inflammation through p38 MAPK activation.
Topics: Antidepressive Agents; Extraembryonic Membranes; Female; Fetal Membranes, Premature Rupture; Fluoxet | 2023 |
The serotonin reuptake inhibitor fluoxetine induces human fetal membrane sterile inflammation through p38 MAPK activation.
Topics: Antidepressive Agents; Extraembryonic Membranes; Female; Fetal Membranes, Premature Rupture; Fluoxet | 2023 |
Inhibitory effects of fluoxetine on the secretion of inflammatory mediators and JAK/STAT3 and JNK/TLR4 gene expression.
Topics: Animals; Cytokines; Fluoxetine; Gene Expression; Inflammation; Inflammation Mediators; Interleukin-6 | 2023 |
Fluoxetine partially alleviates inflammation in the kidney of socially stressed male C57 BL/6 mice.
Topics: Animals; Antidepressive Agents; Depression; Fluoxetine; Inflammation; Kidney; Male; Mice | 2023 |
Fluoxetine restrains allergic inflammation by targeting an FcɛRI-ATP positive feedback loop in mast cells.
Topics: Adenosine Triphosphate; Animals; Cytokines; Feedback; Fluoxetine; Humans; Immunoglobulin E; Inflamma | 2023 |
Effects of in utero exposure to fluoxetine on the gastrointestinal tract of rat offspring.
Topics: Animals; Colitis; Female; Fluoxetine; Humans; Inflammation; Male; Pregnancy; Prenatal Exposure Delay | 2023 |
Fluoxetine Attenuated Anxiety-Like Behaviors in Streptozotocin-Induced Diabetic Mice by Mitigating the Inflammation.
Topics: Animals; Antidepressive Agents; Anxiety; Blotting, Western; Diabetes Mellitus, Experimental; Disease | 2019 |
Inflammation-induced behavioral changes is driven by alterations in Nrf2-dependent apoptosis and autophagy in mouse hippocampus: Role of fluoxetine.
Topics: Animals; Apoptosis; Autophagy; Behavior, Animal; Catalase; Depression; Fluoxetine; Glutathione; Hipp | 2020 |
Effect of Toll-like receptor 4 on depressive-like behaviors induced by chronic social defeat stress.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Cytokines; Depression; Disease | 2020 |
Lysosomotropic drugs enhance pro-inflammatory responses to IL-1β in macrophages by inhibiting internalization of the IL-1 receptor.
Topics: Autophagy; Cell Culture Techniques; Cell Survival; Chloroquine; Chlorpromazine; Endocytosis; Fluoxet | 2020 |
Effects of Stress Exposure during Adolescent Period on Inflammatory Pain Response, Psychoemotional Behavior, and Action of Antidepressants in Prenatally Stressed Adult Male Rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Buspirone; Female; Fluoxetine; Inflammation; Male; | 2020 |
Anti-depressant effect of cerebrolysin in reserpine-induced depression in rats: Behavioral, biochemical, molecular and immunohistochemical evidence.
Topics: Amino Acids; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cyc | 2021 |
Modulation of the Nitric Oxide/BH4 Pathway Protects Against Irradiation-Induced Neuronal Damage.
Topics: Animals; Antidepressive Agents, Second-Generation; Apoptosis; Biopterins; Brain; Brain Injuries; Cra | 2021 |
Short communication: Ex-vivo effects of fluoxetine on production of biomarkers for inflammation and neurodevelopment by the placenta.
Topics: Biomarkers; Brain-Derived Neurotrophic Factor; Cytokines; Depressive Disorder; Female; Fluoxetine; H | 2021 |
Maternal fluoxetine reduces hippocampal inflammation and neurogenesis in adult offspring with sex-specific effects of periadolescent oxytocin.
Topics: Adult Children; Animals; Autism Spectrum Disorder; Doublecortin Protein; Female; Fluoxetine; Hippoca | 2021 |
The effects of desipramine, fluoxetine, or tianeptine on changes in bulbar BDNF levels induced by chronic social instability stress and inflammation.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Desipramine; Disease Models, Anim | 2017 |
Effects of fluoxetine on changes of pain sensitivity in chronic stress model rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Disease Models, Animal; Fluoxetine; Hyperalgesia; | 2017 |
Olive oil and leaf extract prevent fluoxetine-induced hepatotoxicity by attenuating oxidative stress, inflammation and apoptosis.
Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Catalase; Chemi | 2018 |
Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antioxidants; Anxiety; Chronic Disease; Co | 2018 |
Thymoquinone and fluoxetine alleviate depression via attenuating oxidative damage and inflammatory markers in type-2 diabetic rats.
Topics: Animals; Antioxidants; Behavior, Animal; Benzoquinones; Biomarkers; Cytokines; Depression; Diabetes | 2019 |
Perilla aldehyde attenuates CUMS-induced depressive-like behaviors via regulating TXNIP/TRX/NLRP3 pathway in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Carrier Proteins; Caspase Inhibitors; Cell Cycle | 2018 |
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Benzofurans; Citalopram; Depression; Depr | 2018 |
Naringenin protects against oxido-inflammatory aberrations and altered tryptophan metabolism in olfactory bulbectomized-mice model of depression.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain Ch | 2018 |
Tauroursodeoxycholic Acid Ameliorates Lipopolysaccharide-Induced Depression Like Behavior in Mice via the Inhibition of Neuroinflammation and Oxido-Nitrosative Stress.
Topics: Animals; Antidepressive Agents; Cytokines; Depression; Disease Models, Animal; Fluoxetine; Hippocamp | 2019 |
Fluoxetine triggers selective apoptosis in inflammation-induced proliferating (Ki-67
Topics: Animals; Apoptosis; Fluoxetine; Inflammation; Ki-67 Antigen; Lipopolysaccharides; Male; Mice; Phosph | 2019 |
Glucocorticoid receptor dysfunction orchestrates inflammasome effects on chronic obstructive pulmonary disease-induced depression: A potential mechanism underlying the cross talk between lung and brain.
Topics: Animals; Brain; Bronchoalveolar Lavage Fluid; Caspase 1; Cigarette Smoking; Cytokines; Depression; D | 2019 |
N-acetylcysteine attenuates neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat.
Topics: Acetylcysteine; Animals; Antidepressive Agents; Behavior, Animal; Cytokines; Depression; Depressive | 2019 |
Silymarin and silymarin nanoparticles guard against chronic unpredictable mild stress induced depressive-like behavior in mice: involvement of neurogenesis and NLRP3 inflammasome.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Fluoxetine; Hippocampus; Inflammasomes | 2019 |
Fluoxetine suppresses inflammatory reaction in microglia under OGD/R challenge via modulation of NF-κB signaling.
Topics: Animals; Apoptosis; Fluoxetine; Gene Expression Regulation; Glucose; Humans; Inflammation; Interleuk | 2019 |
Disruption of 5-HT2A receptor-PDZ protein interactions alleviates mechanical hypersensitivity in carrageenan-induced inflammation in rats.
Topics: Animals; Bicuculline; Carrageenan; Disks Large Homolog 4 Protein; Fluorobenzenes; Fluoxetine; Hypera | 2013 |
Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats.
Topics: Anhedonia; Animals; Antidepressive Agents; Calcium-Binding Proteins; Carrier Proteins; Chronic Disea | 2014 |
Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-κB, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Aspirin; Blotting, West | 2014 |
Anti-depressant effect of hesperidin in diabetic rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain-Derived Neurotrophic Fa | 2014 |
Anti-depressant effect of hesperidin in diabetic rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain-Derived Neurotrophic Fa | 2014 |
Anti-depressant effect of hesperidin in diabetic rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain-Derived Neurotrophic Fa | 2014 |
Anti-depressant effect of hesperidin in diabetic rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Brain-Derived Neurotrophic Fa | 2014 |
Serotonin 6 receptor controls Alzheimer's disease and depression.
Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid Pre | 2015 |
Knockdown of hippocampal cysteinyl leukotriene receptor 1 prevents depressive behavior and neuroinflammation induced by chronic mild stress in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Cytokines; Depression; Eating; Fluoxetin | 2016 |
Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior.
Topics: Animals; Cytokines; Depression; Fluoxetine; Glycogen Synthase Kinase 3; Hippocampus; HMGB1 Protein; | 2016 |
Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain; Calcium-Binding Proteins; Disease Models, | 2016 |
Comparison of fluoxetine and 1-methyl-L-tryptophan in treatment of depression-like illness in Bacillus Calmette-Guerin-induced inflammatory model of depression in mice.
Topics: Animals; Antidepressive Agents; BCG Vaccine; Depression; Disease Models, Animal; Fluoxetine; Inflamm | 2016 |
Depression-like phenotype by deletion of α7 nicotinic acetylcholine receptor: Role of BDNF-TrkB in nucleus accumbens.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antidepressive Agents; Azepines; Behavior, Animal; | 2016 |
Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Brain-Derived Neurotrophic F | 2017 |
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats.
Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Celecoxib; Central Nervous System Agents; Diclo | 2010 |
Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats.
Topics: Animals; Cytokines; Disease Models, Animal; Extracellular Matrix; Familial Primary Pulmonary Hyperte | 2011 |
Downregulation of osteopontin is associated with fluoxetine amelioration of monocrotaline-induced pulmonary inflammation and vascular remodelling.
Topics: Animals; Dose-Response Relationship, Drug; Down-Regulation; Fluoxetine; Inflammation; Lung; Lung Dis | 2011 |
Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Encephalomyelitis, Autoimmune, Experimental; Fema | 2012 |
Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Encephalomyelitis, Autoimmune, Experimental; Fema | 2012 |
Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Encephalomyelitis, Autoimmune, Experimental; Fema | 2012 |
Fluoxetine promotes remission in acute experimental autoimmune encephalomyelitis in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Encephalomyelitis, Autoimmune, Experimental; Fema | 2012 |
A depressive phenotype induced by Bacille Calmette Guérin in 'susceptible' animals: sensitivity to antidepressants.
Topics: Animals; Antidepressive Agents; BCG Vaccine; Chronic Disease; Depression; Desipramine; Diazepam; Dis | 2013 |
Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anhedonia; Animals; Brain Chemistry; Cognition Disorders; | 2013 |
Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice.
Topics: Acute Disease; Animals; Blood Platelets; Chemotaxis; Endothelium, Vascular; Flow Cytometry; Fluoxeti | 2013 |
Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Carrageenan; Clomipramine; Dise | 2003 |
Studies on the anti-inflammatory effect of fluoxetine in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Carrageenan; Celecoxib; Cyc | 2004 |
Stimulatory effect of antidepressants on the production of IL-6.
Topics: 5-Hydroxytryptophan; Adult; Age Factors; Aging; Antidepressive Agents; Blood Cells; Cyclohexanols; D | 2004 |
Anti-inflammatory properties of desipramine and fluoxetine.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Asthma; Cells, Cultured; Cytokines; Desipr | 2007 |
Fluoxetine reduces inflammatory edema in the rat: involvement of the pituitary-adrenal axis.
Topics: Adrenalectomy; Animals; beta-Endorphin; Corticosterone; Dose-Response Relationship, Drug; Edema; Flu | 1994 |
Peripheral antinociceptive actions of desimipramine and fluoxetine in an inflammatory and neuropathic pain test in the rat.
Topics: Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, | 2000 |