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fluoxetine and Inappropriate ADH Syndrome

fluoxetine has been researched along with Inappropriate ADH Syndrome in 25 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.

Research Excerpts

ExcerptRelevanceReference
" We present a case of an elderly patient who developed hyponatremia with sertraline and SIADH when rechallenged with fluoxetine."7.71Hyponatremia associated with sertraline and fluoxetine: a case report. ( Raphael, K; Tokeshi, J, 2002)
"A search of MEDLINE for reports of hyponatremia and SIADH associated with the use of fluoxetine, fluvoxamine, paroxetine or sertraline published between January 1980 and May 1995."4.79Hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone associated with the use of selective serotonin reuptake inhibitors: a review of spontaneous reports. ( Knowles, SR; Liu, BA; Mittmann, N; Shear, NH, 1996)
"After major depression was diagnosed in a 83-year-old woman, fluoxetine was prescribed."4.78Fluoxetine-induced SIADH: a geriatric occurrence? ( Hall, DL; Kazal, LA; Miller, LG; Noel, ML, 1993)
" We describe the case of a 53-year-old woman that was started on fluoxetine 20 mg/day for depression and nine days later was found to have fluoxetine-induced syndrome of inappropriate secretion of antidiuretic hormone."3.74Pontine and extrapontine osmotic myelinolysis after the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report. ( Bertolucci, CB; Gracia, Cde M; Twardowschy, CA, 2007)
" We describe a case of a 53-year-old woman that was started on fluoxetine 20 mg/day for depression."3.73Severe hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report. ( Bertolucci, CB; Brandão, MA; Gracia, Cde M; Twardowschy, CA, 2006)
" We present a case of an elderly patient who developed hyponatremia with sertraline and SIADH when rechallenged with fluoxetine."3.71Hyponatremia associated with sertraline and fluoxetine: a case report. ( Raphael, K; Tokeshi, J, 2002)
"We report two new cases of severe and reversible hyponatremia associated with routine use of fluoxetine therapy in two elderly women."3.69Syndrome of inappropriate secretion of antidiuretic hormone in two elderly women with elevated serum fluoxetine. ( Bonmarchand, G; Chevron, V; Droy, JM; Girault, C; Goullé, JP; Leroy, J; Richard, JC, 1997)
"Fluoxetine was discontinued."1.29Syndrome of inappropriate secretion of antidiuretic hormone secondary to fluoxetine. ( Birt, JA; Blacksten, JV, 1993)
" Hyponatraemia has previously been described as an adverse effect to fluoxetine and paroxetine, but not to citalopram."1.29[Adverse effects of selective serotonin uptake inhibitors. Hyponatremia caused by Schwartz-Bartter syndrome]. ( Almdal, TP; Christensen, O; Sørensen, HA, 1996)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's18 (72.00)18.2507
2000's6 (24.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Finfgeld, DL1
Twardowschy, CA2
Bertolucci, CB2
Gracia, Cde M2
Brandão, MA1
Ozturk, S1
Ozsenel, EB1
Kazancioglu, R1
Turkmen, A1
Jackson, C1
Carson, W1
Markowitz, J1
Mintzer, J1
van Iperen, CE1
Grootjans-Geerts, I1
Bartelink, AK1
ten Holt, WL1
Klaassen, CH1
Schrijver, G1
Blacksten, JV1
Birt, JA1
Kazal, LA1
Hall, DL1
Miller, LG1
Noel, ML1
Flint, AJ1
Crosby, J1
Genik, JL1
Liu, BA1
Mittmann, N1
Knowles, SR1
Shear, NH1
Burke, D2
Fanker, S1
Franker, S1
Schattner, A1
Skurnik, Y1
Christensen, O1
Sørensen, HA1
Almdal, TP1
Girault, C1
Richard, JC1
Chevron, V1
Goullé, JP1
Droy, JM1
Bonmarchand, G1
Leroy, J1
Demedts, P1
Franck, F1
Wauters, A1
Neels, H1
Romerio, SC1
Radanowicz, V1
Schlienger, RG1
Raphael, K1
Tokeshi, J1
Vishwanath, BM1
Navalgund, AA1
Cusano, W1
Navalgund, KA1
Staab, JP1
Yerkes, SA1
Cheney, EM1
Clayton, AH1
Marik, PE1
van Heerden, W1
Steenkamp, V1
Gommans, JH1
Edwards, RA1
Cohen, BJ1
Mahelsky, M1
Adler, L1
Hwang, AS1
Magraw, RM1

Reviews

5 reviews available for fluoxetine and Inappropriate ADH Syndrome

ArticleYear
SSRI-related hyponatremia among aging adults.
    Journal of psychosocial nursing and mental health services, 2003, Volume: 41, Issue:4

    Topics: Accidental Falls; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; De

2003
[Severe hyponatremia, possibly due to inappropriate antidiuretic hormone secretion, during use of the antidepressant fluoxetine].
    Nederlands tijdschrift voor geneeskunde, 1994, Jun-04, Volume: 138, Issue:23

    Topics: Aged; Aged, 80 and over; Female; Fluoxetine; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male;

1994
Fluoxetine-induced SIADH: a geriatric occurrence?
    The Journal of family practice, 1993, Volume: 36, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Depression; Female; Fluoxetine; Humans; Inappropriate ADH Synd

1993
Hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone associated with the use of selective serotonin reuptake inhibitors: a review of spontaneous reports.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1996, Sep-01, Volume: 155, Issue:5

    Topics: 1-Naphthylamine; Aged; Aged, 80 and over; Female; Fluoxetine; Fluvoxamine; Humans; Hyponatremia; Ina

1996
Fluoxetine and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
    The Australian and New Zealand journal of psychiatry, 1996, Volume: 30, Issue:2

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Depressive Disorder; Diagnosis, D

1996

Other Studies

20 other studies available for fluoxetine and Inappropriate ADH Syndrome

ArticleYear
Severe hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report.
    Arquivos de neuro-psiquiatria, 2006, Volume: 64, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Basal Ganglia; Depression; Female; Fluoxetine; Humans; Ina

2006
Pontine and extrapontine osmotic myelinolysis after the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report.
    Arquivos de neuro-psiquiatria, 2007, Volume: 65, Issue:3B

    Topics: Antidepressive Agents, Second-Generation; Basal Ganglia; Depression; Female; Fluoxetine; Humans; Hyp

2007
A case of fluoxetine-induced syndrome of inappropriate antidiuretic hormone secretion.
    Nature clinical practice. Nephrology, 2008, Volume: 4, Issue:5

    Topics: Fluoxetine; Follow-Up Studies; Humans; Inappropriate ADH Syndrome; Male; Middle Aged; Risk Assessmen

2008
SIADH associated with fluoxetine and sertraline therapy.
    The American journal of psychiatry, 1995, Volume: 152, Issue:5

    Topics: 1-Naphthylamine; Age Factors; Aged; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxeti

1995
[Severe hyponatremia, possibly due to inappropriate antidiuretic hormone secretion, with use of the antidepressive agent fluoxetine].
    Nederlands tijdschrift voor geneeskunde, 1994, Sep-10, Volume: 138, Issue:37

    Topics: Aged; Female; Fluoxetine; Humans; Hyponatremia; Inappropriate ADH Syndrome

1994
Syndrome of inappropriate secretion of antidiuretic hormone secondary to fluoxetine.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Female; Fluoxetine; Humans; Inappropriate ADH Syndrome

1993
Recurrent hyponatremia associated with fluoxetine and paroxetine.
    The American journal of psychiatry, 1996, Volume: 153, Issue:1

    Topics: Aged; Depressive Disorder; Female; Fluoxetine; Humans; Hyponatremia; Inappropriate ADH Syndrome; Par

1996
Fluoxetine-induced SIADH: most likely in the elderly?
    The Australian and New Zealand journal of psychiatry, 1996, Volume: 30, Issue:2

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Depressive Disorder; Female; Fluo

1996
Fluoxetine-induced SIADH.
    Journal of the American Geriatrics Society, 1996, Volume: 44, Issue:11

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Drug Monitoring; Female; Fluoxeti

1996
[Adverse effects of selective serotonin uptake inhibitors. Hyponatremia caused by Schwartz-Bartter syndrome].
    Ugeskrift for laeger, 1996, Nov-25, Volume: 158, Issue:48

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Second-Generation; Antihypert

1996
Syndrome of inappropriate secretion of antidiuretic hormone in two elderly women with elevated serum fluoxetine.
    Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:1

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Contraindications; Female; Fluoxe

1997
Fluoxetine: is the syndrome of inappropriate secretion of antidiuretic hormone in elderly patients associated with elevated serum levels?
    Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:1-2

    Topics: Aged; Antidepressive Agents, Second-Generation; Fluoxetine; Humans; Inappropriate ADH Syndrome; Refe

1998
[SIADH with epileptic seizures and coma in fluoxetine therapy].
    Praxis, 2000, Mar-02, Volume: 89, Issue:10

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Coma; Depressive Disorder; Electr

2000
Hyponatremia associated with sertraline and fluoxetine: a case report.
    Hawaii medical journal, 2002, Volume: 61, Issue:3

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive

2002
Fluoxetine as a cause of SIADH.
    The American journal of psychiatry, 1991, Volume: 148, Issue:4

    Topics: Depressive Disorder; Female; Fluoxetine; Humans; Inappropriate ADH Syndrome; Middle Aged; Sodium

1991
Transient SIADH associated with fluoxetine.
    The American journal of psychiatry, 1990, Volume: 147, Issue:11

    Topics: Depressive Disorder; Fluoxetine; Humans; Inappropriate ADH Syndrome; Male; Middle Aged; Obsessive-Co

1990
Fluoxetine-induced syndrome of inappropriate antidiuretic hormone excretion.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1990, Dec-15, Volume: 78, Issue:12

    Topics: Female; Fluoxetine; Humans; Inappropriate ADH Syndrome; Middle Aged

1990
Fluoxetine and hyponatraemia.
    The New Zealand medical journal, 1990, Mar-14, Volume: 103, Issue:885

    Topics: Aged; Female; Fluoxetine; Humans; Hyponatremia; Inappropriate ADH Syndrome

1990
More cases of SIADH with fluoxetine.
    The American journal of psychiatry, 1990, Volume: 147, Issue:7

    Topics: Aged; Aged, 80 and over; Depressive Disorder; Female; Fluoxetine; Hospitalization; Humans; Inappropr

1990
Syndrome of inappropriate secretion of antidiuretic hormone due to fluoxetine.
    The American journal of psychiatry, 1989, Volume: 146, Issue:3

    Topics: Aged; Depressive Disorder; Fluoxetine; Humans; Inappropriate ADH Syndrome; Male

1989