Page last updated: 2024-10-27

fluoxetine and Hypoxia

fluoxetine has been researched along with Hypoxia in 8 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
" Low-dose fluoxetine administered in the premenstrual phase deserves further attention for management of panic disorders in women."4.02Enhanced responsiveness to hypoxic panicogenic challenge in female rats in late diestrus is suppressed by short-term, low-dose fluoxetine: Involvement of the dorsal raphe nucleus and the dorsal periaqueductal gray. ( Batistela, MF; Frias, AT; Hernandes, PM; Lovick, TA; Vilela-Costa, HH; Zangrossi, H, 2021)
" During exposure to hypoxia (10% O2 for 2 weeks), the animals received one of the specific 5-HTT inhibitors citalopram and fluoxetine (10 mg/kg/day), the selective 5-HT1B/1D receptor antagonist GR127935 (2 and 10 mg/kg/day), or the 5-HT2A receptor antagonist ketanserin (2 mg/kg/day)."3.72Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension. ( Adnot, S; Eddahibi, S; Hamon, M; Marcos, E; Nosjean, A; Pham, MH; Raffestin, B, 2003)
"The 5-HT antagonists ketanserin, mianserin, methysergide, and cyproheptadine and the 5-HT uptake inhibitors fluoxetine and zimeldine were evaluated for their ability to protect against an hypoxia-induced performance deficit in a passive avoidance (PA) task."3.67Manipulation of serotonin protects against an hypoxia-induced deficit of a passive avoidance response in rats. ( DeNoble, VJ; Spencer, KR; Strek, KF, 1989)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Batistela, MF1
Vilela-Costa, HH1
Frias, AT1
Hernandes, PM1
Lovick, TA1
Zangrossi, H1
Mikhailenko, VA1
Butkevich, IP1
Vershinina, EA1
Nagano, R1
Nagano, M1
Nakai, A1
Takeshita, T1
Suzuki, H1
Amador, MHB1
Schauer, KL1
McDonald, MD2
Panlilio, JM1
Marin, S1
Lobl, MB1
Zhu, XH1
Yan, HC1
Zhang, J1
Qu, HD1
Qiu, XS1
Chen, L1
Li, SJ1
Cao, X1
Bean, JC1
Chen, LH1
Qin, XH1
Liu, JH1
Bai, XC1
Mei, L1
Gao, TM1
Marcos, E1
Adnot, S1
Pham, MH1
Nosjean, A1
Raffestin, B1
Hamon, M1
Eddahibi, S1
Strek, KF1
Spencer, KR1
DeNoble, VJ1

Other Studies

8 other studies available for fluoxetine and Hypoxia

ArticleYear
Enhanced responsiveness to hypoxic panicogenic challenge in female rats in late diestrus is suppressed by short-term, low-dose fluoxetine: Involvement of the dorsal raphe nucleus and the dorsal periaqueductal gray.
    Journal of psychopharmacology (Oxford, England), 2021, Volume: 35, Issue:12

    Topics: Animals; Behavior, Animal; Diestrus; Disease Models, Animal; Dorsal Raphe Nucleus; Female; Fluoxetin

2021
Long-Term Effect of Moderate Hypoxia and Chronic Administration of Fluoxetine during the Neonatal Period on Cognitive and Stress-Hormonal Functions in Adult Male Rats.
    Bulletin of experimental biology and medicine, 2023, Volume: 175, Issue:2

    Topics: Animals; Cognition; Corticosterone; Fluoxetine; Hypoxia; Male; Rats; Rats, Wistar; Selective Seroton

2023
Differential effects of neonatal SSRI treatments on hypoxia-induced behavioral changes in male and female offspring.
    Neuroscience, 2017, Sep-30, Volume: 360

    Topics: Animals; Animals, Newborn; Behavior, Animal; Citalopram; Disease Models, Animal; Female; Fluoxetine;

2017
Does fluoxetine exposure affect hypoxia tolerance in the Gulf toadfish, Opsanus beta?
    Aquatic toxicology (Amsterdam, Netherlands), 2018, Volume: 199

    Topics: Animals; Batrachoidiformes; Fluoxetine; Gills; Heart; Hypoxia; Mass Spectrometry; Myocardium; Select

2018
Treatment with the selective serotonin reuptake inhibitor, fluoxetine, attenuates the fish hypoxia response.
    Scientific reports, 2016, 08-08, Volume: 6

    Topics: Animals; Batrachoidiformes; Fluoxetine; Hypoxia; Selective Serotonin Reuptake Inhibitors

2016
Intermittent hypoxia promotes hippocampal neurogenesis and produces antidepressant-like effects in adult rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Sep-22, Volume: 30, Issue:38

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic F

2010
Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension.
    American journal of respiratory and critical care medicine, 2003, Aug-15, Volume: 168, Issue:4

    Topics: Analysis of Variance; Animals; Carrier Proteins; Chronic Disease; Citalopram; Disease Models, Animal

2003
Manipulation of serotonin protects against an hypoxia-induced deficit of a passive avoidance response in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: Animals; Avoidance Learning; Cyproheptadine; Dose-Response Relationship, Drug; Fluoxetine; Hypoxia;

1989