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fluoxetine and Hypothermia, Accidental

fluoxetine has been researched along with Hypothermia, Accidental in 20 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
"The antiobesity agent, fenfluramine, produces hypothermia in rodents by an, as yet, uncharacterized mechanism."7.72Fenfluramine-induced hypothermia is associated with cutaneous dilation in conscious rats. ( Subramanian, S; Vollmer, RR, 2004)
"Depressing functional serotonin or depleting serotonin levels in rat brains with either p-chlorophenylalanine, 5,6-dihydroxytryptamine or raphe lesions greatly enhanced hypothermia induced by chloropromazine (CPZ)."7.66Effects of brain serotonin alterations on hypothermia produced by chlorpromazine in rats. ( Chern, YF; Chow, CF; Li, YP; Lin, MT, 1979)
"Pretreatment with fluoxetine increases extracellular 5-HT due to reuptake inhibition."5.30Modulation of delta9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat. ( Malone, DT; Taylor, DA, 1998)
" A possible mechanism was explored in the tests of antagonism of reserpine-induced ptosis and hypothermia, and 5-HTP induced head twitch response in mice."3.79Antidepressant-like effect of ethanol extract from Zuojin Pill, containing two herbal drugs of Rhizoma Coptidis and Fructus Evodiae, is explained by modulating the monoaminergic neurotransmitter system in mice. ( Cui, YL; Ding, SL; Mao, HP; Qi, XJ; Wang, QS, 2013)
" A possible mechanism was explored in the test of antagonism of reserpine-induced ptosis and hypothermia in mice."3.76Antidepressant-like effect of genipin in mice. ( Chi, W; Cui, YL; Dong, TJ; Gao, S; Hu, LM; Liu, LP; Tian, JS, 2010)
"The antiobesity agent, fenfluramine, produces hypothermia in rodents by an, as yet, uncharacterized mechanism."3.72Fenfluramine-induced hypothermia is associated with cutaneous dilation in conscious rats. ( Subramanian, S; Vollmer, RR, 2004)
"Depressing functional serotonin or depleting serotonin levels in rat brains with either p-chlorophenylalanine, 5,6-dihydroxytryptamine or raphe lesions greatly enhanced hypothermia induced by chloropromazine (CPZ)."3.66Effects of brain serotonin alterations on hypothermia produced by chlorpromazine in rats. ( Chern, YF; Chow, CF; Li, YP; Lin, MT, 1979)
"Depression is a major health problem worldwide."1.38Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects. ( Alvarado, G; Artigas, F; Bortolozzi, A; Carmona, MC; Castañé, A; Cortés, R; Fernández, G; Ferrés-Coy, A; Montefeltro, A; Perales, JC; Santana, N; Semakova, J; Toth, M, 2012)
"Pretreatment with fluoxetine increases extracellular 5-HT due to reuptake inhibition."1.30Modulation of delta9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat. ( Malone, DT; Taylor, DA, 1998)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's3 (15.00)18.2507
2000's8 (40.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Martínez-Esparza, J1
Oficialdegui, AM1
Pérez-Silanes, S1
Heras, B1
Orús, L1
Palop, JA1
Lasheras, B1
Roca, J1
Mourelle, M1
Bosch, A1
Del Castillo, JC1
Tordera, R1
Del Río, J1
Monge, A1
McKeirnan, KC1
Vaitla, K1
Gilbert, R1
Anderson, CB1
Undeberg, MR1
Wang, QS1
Ding, SL1
Mao, HP1
Cui, YL2
Qi, XJ1
Amigó, J1
Díaz, A1
Pilar-Cuéllar, F1
Vidal, R1
Martín, A1
Compan, V1
Pazos, A1
Castro, E1
Overstreet, DH3
Fredericks, K1
Knapp, D1
Breese, G1
McMichael, J1
Tian, JS1
Hu, LM1
Gao, S1
Chi, W1
Dong, TJ1
Liu, LP1
Bortolozzi, A2
Castañé, A2
Semakova, J1
Santana, N2
Alvarado, G1
Cortés, R2
Ferrés-Coy, A2
Fernández, G1
Carmona, MC2
Toth, M2
Perales, JC1
Montefeltro, A2
Artigas, F2
Diaz, SL1
Doly, S1
Narboux-Nême, N1
Fernández, S1
Mazot, P1
Banas, SM1
Boutourlinsky, K1
Moutkine, I1
Belmer, A1
Roumier, A1
Maroteaux, L1
Subramanian, S1
Vollmer, RR1
Rawls, SM2
Cowan, A2
Ding, Z1
Popa, D1
Léna, C1
Alexandre, C1
Adrien, J1
Rubat, C1
Coudert, P1
Bastide, P1
Tronche, P1
Masquelier, I1
Saint Jean, O1
Bourdiol, MC1
Boiffin, A1
Bouchon, JP1
Malone, DT1
Taylor, DA1
Cousins, MS1
Vosmer, G1
Seiden, LS1
Kim, KW1
Kim, HD1
Jung, JS1
Woo, RS1
Kim, HS1
Suh, HW1
Kim, YH1
Song, DK1
Lin, MT1
Chern, YF1
Chow, CF1
Li, YP1

Reviews

2 reviews available for fluoxetine and Hypothermia, Accidental

ArticleYear
Hypothermia as a Possible Symptom of Serotonin Toxicity: A Case Report.
    The Senior care pharmacist, 2023, Jun-01, Volume: 38, Issue:6

    Topics: Fluoxetine; Humans; Hypothermia; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Syndr

2023
Behavioral characteristics of rat lines selected for differential hypothermic responses to cholinergic or serotonergic agonists.
    Behavior genetics, 2002, Volume: 32, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cholinergic Agonists; Cholinester

2002

Other Studies

18 other studies available for fluoxetine and Hypothermia, Accidental

ArticleYear
New 1-aryl-3-(4-arylpiperazin-1-yl)propane derivatives, with dual action at 5-HT1A serotonin receptors and serotonin transporter, as a new class of antidepressants.
    Journal of medicinal chemistry, 2001, Feb-01, Volume: 44, Issue:3

    Topics: Animals; Antidepressive Agents; Avoidance Learning; Carrier Proteins; Colony-Forming Units Assay; Co

2001
Antidepressant-like effect of ethanol extract from Zuojin Pill, containing two herbal drugs of Rhizoma Coptidis and Fructus Evodiae, is explained by modulating the monoaminergic neurotransmitter system in mice.
    Journal of ethnopharmacology, 2013, Jul-09, Volume: 148, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Behavior, Animal; Coptis; Corpus Striatum; Depr

2013
The absence of 5-HT
    Neuropharmacology, 2016, Volume: 111

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anhedonia; Animals; Antidepressive Agents, Second-Generation

2016
Nerve growth factor (NGF) has novel antidepressant-like properties in rats.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 94, Issue:4

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Brain; Corticos

2010
Antidepressant-like effect of genipin in mice.
    Neuroscience letters, 2010, Aug-02, Volume: 479, Issue:3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Blepharoptosis; Depression; D

2010
Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects.
    Molecular psychiatry, 2012, Volume: 17, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Intranasal; Animals; Antidepressive Agents;

2012
5-HT(2B) receptors are required for serotonin-selective antidepressant actions.
    Molecular psychiatry, 2012, Volume: 17, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Diffe

2012
Acute 5-HT₁A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions.
    Psychopharmacology, 2013, Volume: 225, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Behavior, Animal; Disease Models, An

2013
Fenfluramine-induced hypothermia is associated with cutaneous dilation in conscious rats.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:2

    Topics: Animals; Body Temperature; Fenfluramine; Fluoxetine; Hypothermia; Male; Nicotinic Antagonists; Oxyge

2004
Modulation of delta opioid-evoked hypothermia in rats by WAY 100635 and fluoxetine.
    Neuroscience letters, 2006, May-08, Volume: 398, Issue:3

    Topics: Animals; Benzamides; Body Temperature Regulation; Fluoxetine; Hypothermia; Male; Piperazines; Pyridi

2006
5-HT reuptake and 5-HT2 receptors modulate capsaicin-evoked hypothermia in rats.
    Neuroscience letters, 2008, Jan-17, Volume: 430, Issue:3

    Topics: Animals; Body Temperature; Brain; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Dr

2008
Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Apr-02, Volume: 28, Issue:14

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Animals, Newborn; Antidepress

2008
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:2

    Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Bleph

1995
[Bradycardia and hypothermia in an elderly patient receiving fluoxetine].
    Presse medicale (Paris, France : 1983), 1993, Mar-27, Volume: 22, Issue:11

    Topics: Bradycardia; Female; Fluoxetine; Humans; Hypothermia; Middle Aged

1993
Modulation of delta9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat.
    British journal of pharmacology, 1998, Volume: 124, Issue:7

    Topics: Animals; Dose-Response Relationship, Drug; Dronabinol; Fluoxetine; Hypothermia; Rats; Rats, Wistar;

1998
Rats selectively bred for responsiveness to 5-hydroxytryptamine(1A) receptor stimulation: differences in differential reinforcement of low rate 72-second performance and response to serotonergic drugs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Age Factors; Animals; Behavior

2000
Characterization of antidepressant-like effects of p-synephrine stereoisomers.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 364, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Antidepressive

2001
Effects of brain serotonin alterations on hypothermia produced by chlorpromazine in rats.
    Pharmacology, 1979, Volume: 18, Issue:3

    Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Animals; Body Temperature Regulation; Brain; Chlorprom

1979