Page last updated: 2024-10-27

fluoxetine and Hypotension, Postural

fluoxetine has been researched along with Hypotension, Postural in 12 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine appears to cause a low incidence of adverse cardiac effects."5.28Fluoxetine-induced bradycardia and syncope in two patients. ( Ellison, JM; Ely, E; Milofsky, JE, 1990)
"All patients demonstrated orthostatic hypotension (20 mm Hg or greater decline in systolic blood pressure) associated with symptoms (eg, dizziness, vertigo, near syncope) in the baseline state."2.67Fluoxetine hydrochloride for the treatment of severe refractory orthostatic hypotension. ( Grubb, BP; Kosinski, D; Lorton, M; Madu, E; Samoil, D; Wolfe, D, 1994)
"Fluoxetine appears to cause a low incidence of adverse cardiac effects."1.28Fluoxetine-induced bradycardia and syncope in two patients. ( Ellison, JM; Ely, E; Milofsky, JE, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (83.33)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Flores, DL1
Alvarado, I1
Wong, ML1
Licinio, J1
Flockhart, D1
Grubb, BP3
Wolfe, DA1
Samoil, D3
Temesy-Armos, P2
Hahn, H1
Elliott, L1
Kosinski, D2
Wolfe, D1
Lorton, M1
Madu, E1
Akpunonu, B1
Chin, CK1
Roe, CJ1
Thomas, GW1
Azaz-Livshits, TL1
Danenberg, HD1
Roose, SP1
Glassman, AH1
Attia, E1
Woodring, S1
Giardina, EG1
Bigger, JT1
Montastruc, JL1
Pelat, M1
Verwaerde, P1
Brefel-Courbon, C1
Tran, MA1
Blin, O1
Rascol, O1
Senard, JM1
Roberts, RL1
Joyce, PR1
Mulder, RT1
Begg, EJ1
Kennedy, MA1
Feder, R1
Ellison, JM1
Milofsky, JE1
Ely, E1
Downs, JM1
Dahmer, SK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00265291]Phase 2700 participants (Actual)Interventional1999-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for fluoxetine and Hypotension, Postural

ArticleYear
Fluoxetine hydrochloride for the treatment of severe refractory orthostatic hypotension.
    The American journal of medicine, 1994, Volume: 97, Issue:4

    Topics: Aged; Female; Fluoxetine; Humans; Hypotension, Orthostatic; Male; Middle Aged; Prospective Studies;

1994
Fluoxetine in orthostatic hypotension of Parkinson's disease: a clinical and experimental pilot study.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:4

    Topics: Aged; Aged, 80 and over; Animals; Blood Pressure; Denervation; Disease Models, Animal; Dogs; Female;

1998
A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression.
    The pharmacogenomics journal, 2002, Volume: 2, Issue:3

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; ATP Binding Casse

2002

Other Studies

9 other studies available for fluoxetine and Hypotension, Postural

ArticleYear
Clinical implications of genetic polymorphism of CYP2D6 in Mexican Americans.
    Annals of internal medicine, 2004, Jun-01, Volume: 140, Issue:11

    Topics: Adult; Cytochrome P-450 CYP2D6; Depression; Desipramine; Double-Blind Method; Fluoxetine; Humans; Hy

2004
Usefulness of fluoxetine hydrochloride for prevention of resistant upright tilt induced syncope.
    Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:3 Pt 1

    Topics: Adult; Bradycardia; Drug Tolerance; Female; Fluoxetine; Humans; Hypotension, Orthostatic; Male; Post

1993
The use of serotonin reuptake inhibitors for the treatment of recurrent syncope due to carotid sinus hypersensitivity unresponsive to dual chamber cardiac pacing.
    Pacing and clinical electrophysiology : PACE, 1994, Volume: 17, Issue:8

    Topics: 1-Naphthylamine; Aged; Cardiac Pacing, Artificial; Carotid Sinus; Fluoxetine; Follow-Up Studies; Hea

1994
Fluoxetine: a treatment option for severe symptomatic postural hypotension in a diabetic haemodialysis patient.
    Australian and New Zealand journal of medicine, 1996, Volume: 26, Issue:5

    Topics: Diabetes Mellitus, Type 2; Fluoxetine; Humans; Hypotension, Orthostatic; Male; Middle Aged; Renal Di

1996
Tachycardia, orthostatic hypotension and profound weakness due to concomitant use of fluoxetine and nifedipine.
    Pharmacopsychiatry, 1997, Volume: 30, Issue:6

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Drug Interactions; Drug

1997
Cardiovascular effects of fluoxetine in depressed patients with heart disease.
    The American journal of psychiatry, 1998, Volume: 155, Issue:5

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Blood Pressure; Comorbidity; Depressive Disorder; Dru

1998
Bradycardia and syncope induced by fluoxetine.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:3

    Topics: Adult; Blood Pressure; Bradycardia; Depressive Disorder; Dose-Response Relationship, Drug; Female; F

1991
Fluoxetine-induced bradycardia and syncope in two patients.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:9

    Topics: Adult; Bradycardia; Depressive Disorder; Female; Fluoxetine; Humans; Hypotension, Orthostatic; Synco

1990
Fluoxetine and elevated plasma levels of tricyclic antidepressants.
    The American journal of psychiatry, 1990, Volume: 147, Issue:9

    Topics: Antidepressive Agents, Tricyclic; Drug Interactions; Female; Fluoxetine; Humans; Hypotension, Orthos

1990