fluoxetine has been researched along with Hyponatremia in 29 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fluoxetine enhances the National Institutes of Health Stroke Scale (NIHSS) score [mean difference (MD)=-0." | 9.41 | Recovery in Stroke Patients Treated With Fluoxetine Versus Placebo: A Pooled Analysis of 7,165 Patients. ( Ahmed, E; Doheim, MF; Elfil, M; Elsnhory, A; Fathy, A; Hagrass, AI; Hanbal, A; Hasan, MT; Ouerdane, Y; Ragab, KM, 2023) |
| " We present a case of an elderly patient who developed hyponatremia with sertraline and SIADH when rechallenged with fluoxetine." | 7.71 | Hyponatremia associated with sertraline and fluoxetine: a case report. ( Raphael, K; Tokeshi, J, 2002) |
| " Fluoxetine enhances the National Institutes of Health Stroke Scale (NIHSS) score [mean difference (MD)=-0." | 5.41 | Recovery in Stroke Patients Treated With Fluoxetine Versus Placebo: A Pooled Analysis of 7,165 Patients. ( Ahmed, E; Doheim, MF; Elfil, M; Elsnhory, A; Fathy, A; Hagrass, AI; Hanbal, A; Hasan, MT; Ouerdane, Y; Ragab, KM, 2023) |
| "Fluoxetine was discontinued and fluids were restricted." | 5.30 | [Severe hyponatremia during treatment with fluoxetine]. ( Armijo, G; Miranda, M; Miranda, P, 1999) |
| "A search of MEDLINE for reports of hyponatremia and SIADH associated with the use of fluoxetine, fluvoxamine, paroxetine or sertraline published between January 1980 and May 1995." | 4.79 | Hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone associated with the use of selective serotonin reuptake inhibitors: a review of spontaneous reports. ( Knowles, SR; Liu, BA; Mittmann, N; Shear, NH, 1996) |
| " We describe the case of a 53-year-old woman that was started on fluoxetine 20 mg/day for depression and nine days later was found to have fluoxetine-induced syndrome of inappropriate secretion of antidiuretic hormone." | 3.74 | Pontine and extrapontine osmotic myelinolysis after the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report. ( Bertolucci, CB; Gracia, Cde M; Twardowschy, CA, 2007) |
| " We present a case of an elderly patient who developed hyponatremia with sertraline and SIADH when rechallenged with fluoxetine." | 3.71 | Hyponatremia associated with sertraline and fluoxetine: a case report. ( Raphael, K; Tokeshi, J, 2002) |
| "We report two new cases of severe and reversible hyponatremia associated with routine use of fluoxetine therapy in two elderly women." | 3.69 | Syndrome of inappropriate secretion of antidiuretic hormone in two elderly women with elevated serum fluoxetine. ( Bonmarchand, G; Chevron, V; Droy, JM; Girault, C; Goullé, JP; Leroy, J; Richard, JC, 1997) |
| "To quantify the importance of drug-drug interactions (DDIs) in the occurrence of adverse drug reactions (ADRs) reported with serotoninergic reuptake inhibitors in a pharmacovigilance database." | 1.38 | The importance of drug-drug interactions as a cause of adverse drug reactions: a pharmacovigilance study of serotoninergic reuptake inhibitors in France. ( Bagheri, H; Bondon-Guitton, E; Bui, E; Durrieu, G; Lapeyre-Mestre, M; Montastruc, F; Montastruc, JL; Schmitt, L; Sommet, A, 2012) |
| "Low body weight was a particular risk factor." | 1.30 | Incidence and risk factors for hyponatraemia following treatment with fluoxetine or paroxetine in elderly people. ( Begg, EJ; Sainsbury, R; Wilkinson, TJ; Winter, AC, 1999) |
| "Fluoxetine was discontinued and fluids were restricted." | 1.30 | [Severe hyponatremia during treatment with fluoxetine]. ( Armijo, G; Miranda, M; Miranda, P, 1999) |
| " Hyponatraemia has previously been described as an adverse effect to fluoxetine and paroxetine, but not to citalopram." | 1.29 | [Adverse effects of selective serotonin uptake inhibitors. Hyponatremia caused by Schwartz-Bartter syndrome]. ( Almdal, TP; Christensen, O; Sørensen, HA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 17 (58.62) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Elsnhory, A | 1 |
| Hasan, MT | 1 |
| Hagrass, AI | 1 |
| Hanbal, A | 1 |
| Fathy, A | 1 |
| Ahmed, E | 1 |
| Ouerdane, Y | 1 |
| Ragab, KM | 1 |
| Elfil, M | 1 |
| Doheim, MF | 1 |
| Villoslada Muñiz, RL | 1 |
| Molina Campos, L | 1 |
| González González, B | 1 |
| Casado Viñas, JM | 1 |
| Antonio Pérez, A | 1 |
| Das, A | 1 |
| Maiti, A | 1 |
| Sinha, S | 1 |
| Magaldi, AJ | 2 |
| Seguro, AC | 1 |
| Montastruc, F | 1 |
| Sommet, A | 1 |
| Bondon-Guitton, E | 1 |
| Durrieu, G | 1 |
| Bui, E | 1 |
| Bagheri, H | 1 |
| Lapeyre-Mestre, M | 1 |
| Schmitt, L | 1 |
| Montastruc, JL | 1 |
| Stedman, CA | 1 |
| Begg, EJ | 2 |
| Kennedy, MA | 1 |
| Roberts, R | 1 |
| Wilkinson, TJ | 2 |
| Finfgeld, DL | 1 |
| Matsumoto, H | 1 |
| Twardowschy, CA | 1 |
| Bertolucci, CB | 1 |
| Gracia, Cde M | 1 |
| Moyses, ZP | 1 |
| Nakandakari, FK | 1 |
| van Iperen, CE | 2 |
| Grootjans-Geerts, I | 1 |
| Bartelink, AK | 2 |
| ten Holt, WL | 2 |
| Klaassen, CH | 1 |
| Schrijver, G | 2 |
| Walsh, B | 1 |
| Pillans, PI | 1 |
| Coulter, DM | 1 |
| Flint, AJ | 1 |
| Crosby, J | 1 |
| Genik, JL | 1 |
| Joseph, AP | 1 |
| Farmer, A | 1 |
| Taylor, IC | 1 |
| McConnell, JG | 1 |
| Liu, BA | 1 |
| Mittmann, N | 1 |
| Knowles, SR | 1 |
| Shear, NH | 1 |
| Burke, D | 2 |
| Fanker, S | 1 |
| Franker, S | 1 |
| Christensen, O | 1 |
| Sørensen, HA | 1 |
| Almdal, TP | 1 |
| Girault, C | 1 |
| Richard, JC | 1 |
| Chevron, V | 1 |
| Goullé, JP | 1 |
| Droy, JM | 1 |
| Bonmarchand, G | 1 |
| Leroy, J | 1 |
| Strachan, J | 1 |
| Shepherd, J | 1 |
| Winter, AC | 1 |
| Sainsbury, R | 1 |
| Miranda, M | 1 |
| Armijo, G | 1 |
| Miranda, P | 1 |
| Raphael, K | 1 |
| Tokeshi, J | 1 |
| Luque Ramírez, M | 1 |
| Bajo Martínez, A | 1 |
| Bernal Morell, E | 1 |
| Manzano Espinosa, L | 1 |
| Gommans, JH | 1 |
| Edwards, RA | 1 |
6 reviews available for fluoxetine and Hyponatremia
| Article | Year |
|---|---|
Recovery in Stroke Patients Treated With Fluoxetine Versus Placebo: A Pooled Analysis of 7,165 Patients.
Topics: Fluoxetine; Humans; Hyponatremia; PubMed; Stroke; United States | 2023 |
SSRI-related hyponatremia among aging adults.
Topics: Accidental Falls; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; De | 2003 |
[Severe hyponatremia, possibly due to inappropriate antidiuretic hormone secretion, during use of the antidepressant fluoxetine].
Topics: Aged; Aged, 80 and over; Female; Fluoxetine; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; | 1994 |
Fluoxetine and hyponatraemia--a potential hazard in the elderly.
Topics: Aged; Aged, 80 and over; Female; Fluoxetine; Humans; Hyponatremia | 1994 |
Hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone associated with the use of selective serotonin reuptake inhibitors: a review of spontaneous reports.
Topics: 1-Naphthylamine; Aged; Aged, 80 and over; Female; Fluoxetine; Fluvoxamine; Humans; Hyponatremia; Ina | 1996 |
Fluoxetine and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Depressive Disorder; Diagnosis, D | 1996 |
1 trial available for fluoxetine and Hyponatremia
| Article | Year |
|---|---|
Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia.
Topics: Aged; Aged, 80 and over; Cytochrome P-450 CYP2D6; Depressive Disorder; Female; Fluoxetine; Genotype; | 2002 |
22 other studies available for fluoxetine and Hyponatremia
| Article | Year |
|---|---|
[Hyponatraemia associated with the use of serotonin reuptake inhibitors].
Topics: Aged; Female; Fluoxetine; Humans; Hyponatremia; Selective Serotonin Reuptake Inhibitors | 2020 |
Antidepressant Prescription in the Geriatric Population: A Teachable Moment.
Topics: Aged; Antidepressive Agents; Depressive Disorder, Major; Diagnosis, Differential; Female; Fluoxetine | 2016 |
A possible mechanism for severe symptomatic hyponatremia during sibutramine therapy.
Topics: Animals; Appetite Depressants; Cyclobutanes; Fluoxetine; Humans; Hyponatremia; Rats; Selective Serot | 2008 |
The importance of drug-drug interactions as a cause of adverse drug reactions: a pharmacovigilance study of serotoninergic reuptake inhibitors in France.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Antidepressive Agents; Citalopram; Conf | 2012 |
Hyponatremia associated with selective serotonin reuptake inhibitors.
Topics: Age Factors; Aged; Female; Fluoxetine; Humans; Hyponatremia; Risk Factors; Selective Serotonin Reupt | 2005 |
Pontine and extrapontine osmotic myelinolysis after the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report.
Topics: Antidepressive Agents, Second-Generation; Basal Ganglia; Depression; Female; Fluoxetine; Humans; Hyp | 2007 |
Fluoxetine effect on kidney water reabsorption.
Topics: Absorption; Animals; Antidepressive Agents, Second-Generation; Aquaporin 2; Blotting, Western; Elect | 2008 |
[Severe hyponatremia, possibly due to inappropriate antidiuretic hormone secretion, with use of the antidepressive agent fluoxetine].
Topics: Aged; Female; Fluoxetine; Humans; Hyponatremia; Inappropriate ADH Syndrome | 1994 |
Actions of fluoxetine.
Topics: Fluoxetine; Humans; Hyponatremia | 1994 |
Recurrent hyponatremia associated with fluoxetine and paroxetine.
Topics: Aged; Depressive Disorder; Female; Fluoxetine; Humans; Hyponatremia; Inappropriate ADH Syndrome; Par | 1996 |
An unusual case of central pontine myelinolysis.
Topics: Alcoholism; Antidepressive Agents; Brain Diseases; Depressive Disorder; Fluoxetine; Humans; Hyponatr | 1995 |
Severe hyponatraemia associated with selective serotonin reuptake inhibitors.
Topics: 1-Naphthylamine; Aged; Aged, 80 and over; Depressive Disorder; Female; Fluoxetine; Humans; Hyponatre | 1995 |
Severe hyponatremia during therapy with fluoxetine.
Topics: Aged; Antidepressive Agents, Second-Generation; Female; Fluoxetine; Humans; Hyponatremia | 1996 |
Fluoxetine-induced SIADH: most likely in the elderly?
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Depressive Disorder; Female; Fluo | 1996 |
[Adverse effects of selective serotonin uptake inhibitors. Hyponatremia caused by Schwartz-Bartter syndrome].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Second-Generation; Antihypert | 1996 |
Syndrome of inappropriate secretion of antidiuretic hormone in two elderly women with elevated serum fluoxetine.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Contraindications; Female; Fluoxe | 1997 |
Hyponatraemia associated with the use of selective serotonin re-uptake inhibitors.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Dementia; Depressive Disorder; Dr | 1998 |
Incidence and risk factors for hyponatraemia following treatment with fluoxetine or paroxetine in elderly people.
Topics: Aged; Antidepressive Agents, Second-Generation; Body Weight; Female; Fluoxetine; Humans; Hyponatremi | 1999 |
[Severe hyponatremia during treatment with fluoxetine].
Topics: Aged; Antidepressive Agents, Second-Generation; Depressive Disorder; Female; Fluoxetine; Humans; Hyp | 1999 |
Hyponatremia associated with sertraline and fluoxetine: a case report.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive | 2002 |
[Severe hyponatremia associated with the use of fluoxetine in the elderly].
Topics: Aged; Aged, 80 and over; Depression; Female; Fluoxetine; Humans; Hyponatremia; Selective Serotonin R | 2002 |
Fluoxetine and hyponatraemia.
Topics: Aged; Female; Fluoxetine; Humans; Hyponatremia; Inappropriate ADH Syndrome | 1990 |