Page last updated: 2024-10-27

fluoxetine and Hot Flashes

fluoxetine has been researched along with Hot Flashes in 12 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Hot Flashes: A sudden, temporary sensation of heat predominantly experienced by some women during MENOPAUSE. (Random House Unabridged Dictionary, 2d ed)

Research Excerpts

ExcerptRelevanceReference
" With this in mind, a single-arm clinical trial low-dose regimen of Fluoxetine (10 mg/day for 4 weeks) was given to twenty symptomatic breast cancer patients."9.11Hot-flashes in breast cancer survivors: effectiveness of low-dosage fluoxetine. A pilot study. ( Atlante, M; Barbati, A; Galati, M; Giannarelli, D; Mariani, L; Quattrini, M, 2005)
"This trial used a double-blinded, randomized, two-period (4 weeks per period), cross-over methodology to study the efficacy of fluoxetine (20 mg/d) for treating hot flashes in women with a history of breast cancer or a concern regarding the use of estrogen (because of breast cancer risk)."9.10Phase III evaluation of fluoxetine for treatment of hot flashes. ( Halyard, MY; Loprinzi, CL; Mailliard, JA; Novotny, PJ; Perez, EA; Pruthi, S; Quella, SK; Rummans, TA; Sloan, JA; Stella, PJ, 2002)
" In both treatment rounds, gabapentin caused greater reductions in the severity of hot flashes than did fluoxetine (P<0."5.20A crossover study comparing gabapentin and fluoxetine for the treatment of vasomotor symptoms among postmenopausal women. ( Ghorbani, R; Mohseni, A; Rahmanian, M, 2015)
" With this in mind, a single-arm clinical trial low-dose regimen of Fluoxetine (10 mg/day for 4 weeks) was given to twenty symptomatic breast cancer patients."5.11Hot-flashes in breast cancer survivors: effectiveness of low-dosage fluoxetine. A pilot study. ( Atlante, M; Barbati, A; Galati, M; Giannarelli, D; Mariani, L; Quattrini, M, 2005)
"This trial used a double-blinded, randomized, two-period (4 weeks per period), cross-over methodology to study the efficacy of fluoxetine (20 mg/d) for treating hot flashes in women with a history of breast cancer or a concern regarding the use of estrogen (because of breast cancer risk)."5.10Phase III evaluation of fluoxetine for treatment of hot flashes. ( Halyard, MY; Loprinzi, CL; Mailliard, JA; Novotny, PJ; Perez, EA; Pruthi, S; Quella, SK; Rummans, TA; Sloan, JA; Stella, PJ, 2002)
"Results from these trials indicate that paroxetine, citalopram, escitalopram, venlafaxine, and desvenlafaxine are effective in reducing the frequency and severity of hot flashes."4.91The efficacy and tolerability of SSRI/SNRIs in the treatment of vasomotor symptoms in menopausal women: a systematic review. ( Handley, AP; Williams, M, 2015)
"Migraine is affected by fluctuating estrogen levels so it is not surprising that the perimenopause is a time of peak rate of change of migraine prevalence in women."2.48Perimenopausal migraine in women with vasomotor symptoms. ( MacGregor, EA, 2012)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (58.33)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Handley, AP1
Williams, M1
Rahmanian, M1
Mohseni, A1
Ghorbani, R1
Zhu, X1
Liew, Y1
Liu, ZL1
MacGregor, EA1
Prelle, K1
Igl, BW1
Obendorf, M1
Girbig, D1
Lehmann, T1
Patchev, VK1
Goetz, MP1
Loprinzi, CL2
Mariani, L1
Quattrini, M1
Atlante, M1
Galati, M1
Barbati, A1
Giannarelli, D1
Albertazzi, P1
Maswood, N1
Cosmi, S1
Alfinito, PD1
Leventhal, L1
Deecher, DC1
Alexander, IM1
Moore, A1
Sloan, JA1
Perez, EA1
Quella, SK1
Stella, PJ1
Mailliard, JA1
Halyard, MY1
Pruthi, S1
Novotny, PJ1
Rummans, TA1

Reviews

6 reviews available for fluoxetine and Hot Flashes

ArticleYear
The efficacy and tolerability of SSRI/SNRIs in the treatment of vasomotor symptoms in menopausal women: a systematic review.
    Journal of the American Association of Nurse Practitioners, 2015, Volume: 27, Issue:1

    Topics: Adult; Aged; Citalopram; Desvenlafaxine Succinate; Female; Fluoxetine; Hot Flashes; Humans; Menopaus

2015
Chinese herbal medicine for menopausal symptoms.
    The Cochrane database of systematic reviews, 2016, Mar-15, Volume: 3

    Topics: Drugs, Chinese Herbal; Estazolam; Female; Fluoxetine; Hormone Replacement Therapy; Hot Flashes; Huma

2016
Perimenopausal migraine in women with vasomotor symptoms.
    Maturitas, 2012, Volume: 71, Issue:1

    Topics: Amines; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Estrogens; Female; Fluoxetine; Ga

2012
A hot flash on tamoxifen metabolism.
    Journal of the National Cancer Institute, 2003, Dec-03, Volume: 95, Issue:23

    Topics: Antidepressive Agents, Second-Generation; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cyclohe

2003
Noradrenergic and serotonergic modulation to treat vasomotor symptoms.
    The journal of the British Menopause Society, 2006, Volume: 12, Issue:1

    Topics: Citalopram; Cyclohexanols; Female; Fluoxetine; Hot Flashes; Humans; Menopause; Mianserin; Mirtazapin

2006
Treating vasomotor symptoms of menopause: the nurse practitioner's perspective.
    Journal of the American Academy of Nurse Practitioners, 2007, Volume: 19, Issue:3

    Topics: Adrenergic alpha-Agonists; Algorithms; Amines; Citalopram; Clonidine; Complementary Therapies; Cyclo

2007

Trials

3 trials available for fluoxetine and Hot Flashes

ArticleYear
A crossover study comparing gabapentin and fluoxetine for the treatment of vasomotor symptoms among postmenopausal women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015, Volume: 131, Issue:1

    Topics: Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female;

2015
Hot-flashes in breast cancer survivors: effectiveness of low-dosage fluoxetine. A pilot study.
    Journal of experimental & clinical cancer research : CR, 2005, Volume: 24, Issue:3

    Topics: Adult; Breast Neoplasms; Dose-Response Relationship, Drug; Female; Fluoxetine; Hot Flashes; Humans;

2005
Phase III evaluation of fluoxetine for treatment of hot flashes.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Mar-15, Volume: 20, Issue:6

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Bayes Theorem; Breast Neoplasms; Chi-Square D

2002

Other Studies

3 other studies available for fluoxetine and Hot Flashes

ArticleYear
Endpoints of drug discovery for menopausal vasomotor symptoms: interpretation of data from a proxy of disease.
    Menopause (New York, N.Y.), 2012, Volume: 19, Issue:8

    Topics: Acetamides; Amines; Animals; Body Temperature Regulation; Cyclohexanecarboxylic Acids; Cyclohexanols

2012
Treating hot flashes with drugs: an update.
    Harvard women's health watch, 2002, Volume: 9, Issue:12

    Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents, Second-Generation; Antihypertensive Agents

2002
The role of the selective serotonin reuptake inhibitor fluoxetine in temperature regulation in ovariectomized rat models.
    Neuroendocrinology, 2006, Volume: 84, Issue:5

    Topics: Animals; Body Temperature Regulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug

2006