Page last updated: 2024-10-27

fluoxetine and Hemorrhagic Stroke

fluoxetine has been researched along with Hemorrhagic Stroke in 2 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Hemorrhagic Stroke: Stroke due to rupture of a weakened blood vessel in the brain (e.g., CEREBRAL HEMISPHERES; CEREBELLUM; SUBARACHNOID SPACE).

Research Excerpts

ExcerptRelevanceReference
"The AFFINITY trial (Assessment of Fluoxetine in Stroke Recovery) reported that oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and seizures."9.41Twelve-Month Outcomes of the AFFINITY Trial of Fluoxetine for Functional Recovery After Acute Stroke: AFFINITY Trial Steering Committee on Behalf of the AFFINITY Trial Collaboration. ( Almeida, OP; Anderson, CS; Billot, L; Dennis, MS; Etherton-Beer, C; Flicker, L; Ford, AH; Gommans, J; Hackett, ML; Hankey, GJ; Jan, S; Lundström, E; Lung, T; Mead, GE; Sunnerhagen, KS; Thang-Nguyen, H; Yi, Q, 2021)
"The AFFINITY trial (Assessment of Fluoxetine in Stroke Recovery) reported that oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and seizures."5.41Twelve-Month Outcomes of the AFFINITY Trial of Fluoxetine for Functional Recovery After Acute Stroke: AFFINITY Trial Steering Committee on Behalf of the AFFINITY Trial Collaboration. ( Almeida, OP; Anderson, CS; Billot, L; Dennis, MS; Etherton-Beer, C; Flicker, L; Ford, AH; Gommans, J; Hackett, ML; Hankey, GJ; Jan, S; Lundström, E; Lung, T; Mead, GE; Sunnerhagen, KS; Thang-Nguyen, H; Yi, Q, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Marquez-Romero, JM1
Reyes-Martínez, M1
Huerta-Franco, MR1
Ruiz-Franco, A1
Silos, H1
Arauz, A1
Hankey, GJ1
Hackett, ML1
Almeida, OP1
Flicker, L1
Mead, GE1
Dennis, MS1
Etherton-Beer, C1
Ford, AH1
Billot, L1
Jan, S1
Lung, T1
Lundström, E1
Sunnerhagen, KS1
Anderson, CS1
Thang-Nguyen, H1
Gommans, J1
Yi, Q1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Fluoxetine for Motor Recovery After Acute Intracerebral Hemorrhage (FMRICH): a Randomised Placebo-controlled Trial[NCT01737541]Phase 332 participants (Actual)Interventional2012-11-30Terminated (stopped due to Study recruitment was suspended due to lack of funding)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for fluoxetine and Hemorrhagic Stroke

ArticleYear
Fluoxetine for motor recovery after acute intracerebral hemorrhage, the FMRICH trial.
    Clinical neurology and neurosurgery, 2020, Volume: 190

    Topics: Aged; Basal Ganglia Hemorrhage; Double-Blind Method; Female; Fluoxetine; Hemorrhagic Stroke; Humans;

2020
Twelve-Month Outcomes of the AFFINITY Trial of Fluoxetine for Functional Recovery After Acute Stroke: AFFINITY Trial Steering Committee on Behalf of the AFFINITY Trial Collaboration.
    Stroke, 2021, Volume: 52, Issue:8

    Topics: Accidental Falls; Affect; Aged; Cognition; Double-Blind Method; Fatigue; Female; Fluoxetine; Fractur

2021