Page last updated: 2024-10-27

fluoxetine and Hemiplegia

fluoxetine has been researched along with Hemiplegia in 3 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Hemiplegia: Severe or complete loss of motor function on one side of the body. This condition is usually caused by BRAIN DISEASES that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, BRAIN STEM lesions; cervical SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; and other conditions may manifest as hemiplegia. The term hemiparesis (see PARESIS) refers to mild to moderate weakness involving one side of the body.

Research Excerpts

ExcerptRelevanceReference
" Recent hemiplegic patients (<3 months) suffering from major depressive disorder (determined by International Classification of Diseases, 10th Revision, and Montgomery-Asberg Depression Rating Scale [MADRS] >19) were randomized to receive either 20 mg/d fluoxetine (FLX) or placebo for 6 weeks."9.09Fluoxetine in early poststroke depression: a double-blind placebo-controlled study. ( Barat, M; Joseph, PA; Mazaux, JM; Petit, H; Wiart, L, 2000)
" Recent hemiplegic patients (<3 months) suffering from major depressive disorder (determined by International Classification of Diseases, 10th Revision, and Montgomery-Asberg Depression Rating Scale [MADRS] >19) were randomized to receive either 20 mg/d fluoxetine (FLX) or placebo for 6 weeks."5.09Fluoxetine in early poststroke depression: a double-blind placebo-controlled study. ( Barat, M; Joseph, PA; Mazaux, JM; Petit, H; Wiart, L, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Majeed, F1
Kamal, AK1
Dam, M1
Tonin, P1
De Boni, A1
Pizzolato, G1
Casson, S1
Ermani, M1
Freo, U1
Piron, L1
Battistin, L1
Wiart, L1
Petit, H1
Joseph, PA1
Mazaux, JM1
Barat, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of 3 Months Daily Treatment With Selective Serotonin Reuptake Inhibitor (SSRI, Fluoxetine) on Motor Rehabilitation After Ischemic Stroke. FLAME Trial[NCT00657163]Phase 2100 participants (Anticipated)Interventional2005-03-31Completed
Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction[NCT02386475]Phase 439 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for fluoxetine and Hemiplegia

ArticleYear
Can selective serotonin reuptake inhibitors (SSRI) improve motor recovery after stroke? What is the role of neuroplasticity?
    JPMA. The Journal of the Pakistan Medical Association, 2011, Volume: 61, Issue:11

    Topics: Aged; Evidence-Based Medicine; Female; Fluoxetine; Hemiplegia; Humans; Male; Middle Aged; Motor Skil

2011
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera

1996
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera

1996
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera

1996
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera

1996
Fluoxetine in early poststroke depression: a double-blind placebo-controlled study.
    Stroke, 2000, Volume: 31, Issue:8

    Topics: Aged; Antidepressive Agents, Second-Generation; Depression; Double-Blind Method; Female; Fluoxetine;

2000