fluoxetine has been researched along with Heart Failure in 8 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to examine the pharmacokinetic and pharmacodynamic consequences of concomitant administration of fluoxetine and carvedilol in heart failure patients." | 9.09 | Effect of fluoxetine on carvedilol pharmacokinetics, CYP2D6 activity, and autonomic balance in heart failure patients. ( Adams, KF; Carson, SW; Cascio, WE; Graff, DW; Patterson, JH; Pieper, JA; Williamson, KM, 2001) |
| "The objective of this study was to examine the pharmacokinetic and pharmacodynamic consequences of concomitant administration of fluoxetine and carvedilol in heart failure patients." | 5.09 | Effect of fluoxetine on carvedilol pharmacokinetics, CYP2D6 activity, and autonomic balance in heart failure patients. ( Adams, KF; Carson, SW; Cascio, WE; Graff, DW; Patterson, JH; Pieper, JA; Williamson, KM, 2001) |
| "To investigate the effect of fluoxetine on neurite growth inhibitor (Nogo) expession and collagen production of cardiac tissue in rats with right heart failure and pulmonary hypertension." | 3.83 | [Effects of Fluoxetine on Nogo Expression and Collagen Production with Decrease of Pulmonary Artery Pressure in Rats with Right Ventricular Failure.] ( Chen, YC; Nie, H; Ran, X; Zhao, JX, 2016) |
| "Treatment of rats with monocrotaline (MCT) leads to pulmonary hypertension, right ventricular (RV) hypertrophy, and finally to RV heart failure." | 3.71 | Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure. ( Beilfuss, A; Brandt, K; Brodde, OE; Heinroth-Hoffmann, I; Leineweber, K; Pönicke, K; Wludyka, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ran, X | 1 |
| Zhao, JX | 1 |
| Nie, H | 1 |
| Chen, YC | 1 |
| Lopes, LM | 1 |
| Carrilho, MC | 1 |
| Francisco, RP | 1 |
| Lopes, MA | 1 |
| Krebs, VL | 1 |
| Zugaib, M | 1 |
| Lekakis, J | 1 |
| Ikonomidis, I | 1 |
| Papoutsi, Z | 1 |
| Moutsatsou, P | 1 |
| Nikolaou, M | 1 |
| Parissis, J | 1 |
| Kremastinos, DT | 1 |
| Labos, C | 1 |
| Dasgupta, K | 1 |
| Nedjar, H | 1 |
| Turecki, G | 1 |
| Rahme, E | 1 |
| Henze, M | 1 |
| Tiniakov, R | 1 |
| Samarel, A | 1 |
| Holmes, E | 1 |
| Scrogin, K | 1 |
| Leineweber, K | 2 |
| Brandt, K | 1 |
| Wludyka, B | 1 |
| Beilfuss, A | 1 |
| Pönicke, K | 1 |
| Heinroth-Hoffmann, I | 1 |
| Brodde, OE | 2 |
| Seyfarth, T | 1 |
| Graff, DW | 1 |
| Williamson, KM | 1 |
| Pieper, JA | 1 |
| Carson, SW | 1 |
| Adams, KF | 1 |
| Cascio, WE | 1 |
| Patterson, JH | 1 |
2 trials available for fluoxetine and Heart Failure
| Article | Year |
|---|---|
Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules.
Topics: Adult; Aged; Aorta; Cell Adhesion; Cell Survival; Chronic Disease; Citalopram; Depression; Endotheli | 2010 |
Effect of fluoxetine on carvedilol pharmacokinetics, CYP2D6 activity, and autonomic balance in heart failure patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antidepressive Agents, Second-Generation; Autonomic Nervou | 2001 |
6 other studies available for fluoxetine and Heart Failure
| Article | Year |
|---|---|
[Effects of Fluoxetine on Nogo Expression and Collagen Production with Decrease of Pulmonary Artery Pressure in Rats with Right Ventricular Failure.]
Topics: Animals; Collagen; Fluoxetine; Heart Failure; Hypertension, Pulmonary; Male; Nogo Proteins; Pulmonar | 2016 |
Fetal ductus arteriosus constriction and closure: analysis of the causes and perinatal outcome related to 45 consecutive cases.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Caffeine; Central N | 2016 |
Risk of bleeding associated with combined use of selective serotonin reuptake inhibitors and antiplatelet therapy following acute myocardial infarction.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Angioplasty; Anticoagulants; Antihypertensive Ag | 2011 |
Chronic fluoxetine reduces autonomic control of cardiac rhythms in rats with congestive heart failure.
Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Catecholamines; Coronary Ve | 2013 |
Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.
Topics: Animals; Binding, Competitive; Cell Membrane; Disease Models, Animal; Eye Proteins; Fluoxetine; G-Pr | 2002 |
Chamber-specific alterations of noradrenaline uptake (uptake(1)) in right ventricles of monocrotaline-treated rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Cocaine; Desipramine; Dopamine Uptake I | 2000 |