fluoxetine has been researched along with Glioma in 8 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to evaluate the synergistic killing effect of fluoxetine (FL) with IR on glioma cancer cell (U-87 MG), as well as radioprotective effect of FL against cellular toxicity induced by IR on non-malignant human fibroblast cell (HFFF2)." | 7.96 | Fluoxetine as an antidepressant medicine improves the effects of ionizing radiation for the treatment of glioma. ( Asgarian-Omran, H; Farzipour, S; Ghasemi, A; Hassanzadeh, S; Hosseinimehr, SJ; Najafi, SH; Shafiee, F, 2020) |
| "Although temozolomide (TMZ) is the most effective chemotherapy agent for glioma, chemotherapy resistance has limited its clinical use." | 7.83 | Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells. ( Chen, MH; Chen, W; Ma, J; Sun, LL; Wang, DC; Wang, FZ; Wang, H; Wang, XD; Yang, YR, 2016) |
| "In C6 glioma cells, we studied acute administration of SSRI antidepressants - fluoxetine, sertraline and citalopram." | 7.78 | Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells. ( Kováru, F; Kovárů, H; Lisá, V, 2012) |
| "We studied the effect of acute administration of fluoxetine or NECA agonist of adenosine receptor (GPCR) on C6 glioma cells and natural killer (NK) cell line, innate immunity." | 7.77 | Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes. ( Fiserová, A; Kovaru, F; Kovárů, H; Lisá, V; Ondráčkova, P, 2011) |
| " The purpose of this study was to evaluate the synergistic killing effect of fluoxetine (FL) with IR on glioma cancer cell (U-87 MG), as well as radioprotective effect of FL against cellular toxicity induced by IR on non-malignant human fibroblast cell (HFFF2)." | 3.96 | Fluoxetine as an antidepressant medicine improves the effects of ionizing radiation for the treatment of glioma. ( Asgarian-Omran, H; Farzipour, S; Ghasemi, A; Hassanzadeh, S; Hosseinimehr, SJ; Najafi, SH; Shafiee, F, 2020) |
| "Although temozolomide (TMZ) is the most effective chemotherapy agent for glioma, chemotherapy resistance has limited its clinical use." | 3.83 | Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells. ( Chen, MH; Chen, W; Ma, J; Sun, LL; Wang, DC; Wang, FZ; Wang, H; Wang, XD; Yang, YR, 2016) |
| "In C6 glioma cells, we studied acute administration of SSRI antidepressants - fluoxetine, sertraline and citalopram." | 3.78 | Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells. ( Kováru, F; Kovárů, H; Lisá, V, 2012) |
| "We studied the effect of acute administration of fluoxetine or NECA agonist of adenosine receptor (GPCR) on C6 glioma cells and natural killer (NK) cell line, innate immunity." | 3.77 | Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes. ( Fiserová, A; Kovaru, F; Kovárů, H; Lisá, V; Ondráčkova, P, 2011) |
| "Previous studies have demonstrated that chronic treatment of C6 glioma cells with the antidepressants desipramine and fluoxetine increases the Triton X-100 solubility of the G protein Gsalpha (Toki et al." | 3.71 | Chronic treatment of C6 glioma cells with antidepressant drugs results in a redistribution of Gsalpha. ( Donati, RJ; Rasenick, MM; Thukral, C, 2001) |
| "Gel electrophoresis of DNA was used for estimation of DNA changes caused in C6 glioma cells by treatment with psychotropic drugs (imipramine, amitryptiline and fluoxetine)." | 3.69 | Estimation of apoptosis in C6 glioma cells treated with antidepressants. ( Kovárů, H; Lisá, V; Lukásová, E; Rittich, B; Spanová, A, 1997) |
| "Management and resolution of the hydrocephalus was temporally associated with an improvement in his OCD compulsion symptoms." | 1.43 | Pediatric Obsessive-Compulsive Disorder Exacerbation and Obstructive Hydrocephalus: A Case Report. ( Bleakley, C; Leung, A; Loh, A; Saran, K; Stewart, SE, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Hosseinimehr, SJ | 1 |
| Najafi, SH | 1 |
| Shafiee, F | 1 |
| Hassanzadeh, S | 1 |
| Farzipour, S | 1 |
| Ghasemi, A | 1 |
| Asgarian-Omran, H | 1 |
| Ma, J | 1 |
| Yang, YR | 1 |
| Chen, W | 1 |
| Chen, MH | 1 |
| Wang, H | 1 |
| Wang, XD | 1 |
| Sun, LL | 1 |
| Wang, FZ | 1 |
| Wang, DC | 1 |
| Leung, A | 1 |
| Bleakley, C | 1 |
| Loh, A | 1 |
| Saran, K | 1 |
| Stewart, SE | 1 |
| Kovárů, H | 3 |
| Kovaru, F | 2 |
| Ondráčkova, P | 1 |
| Lisá, V | 3 |
| Fiserová, A | 1 |
| Malynn, S | 1 |
| Campos-Torres, A | 1 |
| Moynagh, P | 1 |
| Haase, J | 1 |
| Spanová, A | 1 |
| Lukásová, E | 1 |
| Rittich, B | 1 |
| Donati, RJ | 1 |
| Thukral, C | 1 |
| Rasenick, MM | 1 |
8 other studies available for fluoxetine and Glioma
| Article | Year |
|---|---|
Fluoxetine as an antidepressant medicine improves the effects of ionizing radiation for the treatment of glioma.
Topics: Antidepressive Agents, Second-Generation; Apoptosis; Fluoxetine; Glioma; Humans; Radiation, Ionizing | 2020 |
Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Prolif | 2016 |
Pediatric Obsessive-Compulsive Disorder Exacerbation and Obstructive Hydrocephalus: A Case Report.
Topics: Brain Neoplasms; Child; Fluoxetine; Glioma; Humans; Hydrocephalus; Male; Obsessive-Compulsive Disord | 2016 |
Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents, Tricyclic; Brain Neoplasms; Cell | 2011 |
Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Brain Neoplasms; Cell Line, Tumor; Citalopram; Depressio | 2012 |
The pro-inflammatory cytokine TNF-α regulates the activity and expression of the serotonin transporter (SERT) in astrocytes.
Topics: Astrocytes; Cell Line, Tumor; Citalopram; Fluoxetine; Glioma; Humans; Imidazoles; p38 Mitogen-Activa | 2013 |
Estimation of apoptosis in C6 glioma cells treated with antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Apoptosis; DNA Fragmentation; Fluoxetine; Glioma; Humans; Imip | 1997 |
Chronic treatment of C6 glioma cells with antidepressant drugs results in a redistribution of Gsalpha.
Topics: Animals; Antidepressive Agents; Chlorpromazine; Desipramine; Fluoxetine; Glioma; GTP-Binding Protein | 2001 |