fluoxetine has been researched along with Fibromyalgia in 23 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "As described elsewhere the oral administration of 5 mg of the 5-HT3-receptor-antagonist Tropisetron in fibromyalgia exhibited less amelioration of pain in patients with a depression in comparison to patients without depression." | 9.10 | [The influence of depression on the effect of Tropisetron in the therapy of fibromyalgia]. ( Müller, W; Stratz, T; Varga, B, 2003) |
| "To assess the efficacy of fluoxetine in the treatment of patients with fibromyalgia." | 9.10 | A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. ( Arnold, LM; Berno, SE; Hess, EV; Hudson, JI; Keck, PE; Welge, JA, 2002) |
| "To study the effect of fluoxetine (FL) and amitriptyline (AM), alone and in combination, in patients with fibromyalgia (FM)." | 9.08 | A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia. ( Goldenberg, D; Mayskiy, M; Mossey, C; Ruthazer, R; Schmid, C, 1996) |
| "The aim of this study is to evaluate the effectiveness of fluoxetin associated with cyclobenzaprine vs cyclobenzaprine in the treatment of fibromyalgia." | 9.07 | [Fluoxetin combined with cyclobenzaprine in the treatment of fibromyalgia]. ( Bellandi, F; Cantini, F; Di Munno, O; Niccoli, L, 1994) |
| "Peak power and fatigue index increased, and VO(2max) and VT did not change with both fluoxetine and amitriptyline." | 5.12 | Comparison of the effects of two antidepressants on exercise performance of the female patients with fibromyalgia. ( Gökbel, H; Levendoğlu, F; Okudan, N; Ozerbil, O, 2006) |
| "As described elsewhere the oral administration of 5 mg of the 5-HT3-receptor-antagonist Tropisetron in fibromyalgia exhibited less amelioration of pain in patients with a depression in comparison to patients without depression." | 5.10 | [The influence of depression on the effect of Tropisetron in the therapy of fibromyalgia]. ( Müller, W; Stratz, T; Varga, B, 2003) |
| "To assess the efficacy of fluoxetine in the treatment of patients with fibromyalgia." | 5.10 | A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. ( Arnold, LM; Berno, SE; Hess, EV; Hudson, JI; Keck, PE; Welge, JA, 2002) |
| "To study the effect of fluoxetine (FL) and amitriptyline (AM), alone and in combination, in patients with fibromyalgia (FM)." | 5.08 | A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia. ( Goldenberg, D; Mayskiy, M; Mossey, C; Ruthazer, R; Schmid, C, 1996) |
| "The aim of this study is to evaluate the effectiveness of fluoxetin associated with cyclobenzaprine vs cyclobenzaprine in the treatment of fibromyalgia." | 5.07 | [Fluoxetin combined with cyclobenzaprine in the treatment of fibromyalgia]. ( Bellandi, F; Cantini, F; Di Munno, O; Niccoli, L, 1994) |
| "Familial Mediterranean Fever (FMF) is characterized by recurrent acute attacks of fever and serositis, and colchicine is the primary treatment." | 3.74 | Selective serotonin reuptake inhibitors reduce the attack frequency in familial mediterranean Fever. ( Calgüneri, M; Ertenli, I; Kaymak, SU; Kiraz, S; Onat, AM; Ozçakar, L; Oztürk, MA; Ureten, K, 2007) |
| "Community- and center-based rheumatologists enrolled patients with fibromyalgia syndrome in randomized, double-blind, multi-crossover, N-of-1 trials comparing amitriptyline and the combination amitriptyline and fluoxetine." | 3.73 | Lessons learned combining N-of-1 trials to assess fibromyalgia therapies. ( Feuer, JM; Fischer, PA; Goldenberg, DL; Kieval, RI; Mogavero, N; Rapoport, RJ; Ruthazer, R; Schmid, CH; Selker, HP; Stotsky, SA; Winston, E; Zucker, DR, 2006) |
| "Fibromyalgia is a chronic widespread pain condition affecting millions of people worldwide." | 2.58 | Combination pharmacotherapy for the treatment of fibromyalgia in adults. ( Gilron, I; Moore, RA; Shum, B; Thorpe, J; Wiffen, PJ, 2018) |
| "Fibromyalgia is a clinically well-defined chronic condition with a biopsychosocial aetiology." | 2.52 | Selective serotonin reuptake inhibitors for fibromyalgia syndrome. ( Cantrell, SE; Häuser, W; Nishishinya, MB; Urrútia, G; Walitt, B, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 11 (47.83) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hernandez-Leon, A | 1 |
| Fernández-Guasti, A | 1 |
| Martínez, A | 1 |
| Pellicer, F | 1 |
| González-Trujano, ME | 1 |
| Thorpe, J | 1 |
| Shum, B | 1 |
| Moore, RA | 1 |
| Wiffen, PJ | 1 |
| Gilron, I | 1 |
| Walitt, B | 1 |
| Urrútia, G | 1 |
| Nishishinya, MB | 1 |
| Cantrell, SE | 1 |
| Häuser, W | 1 |
| Adams, SM | 1 |
| Hussain, SA | 1 |
| Al-Khalifa, II | 1 |
| Jasim, NA | 1 |
| Gorial, FI | 1 |
| Mariutto, EN | 1 |
| Stanford, SB | 1 |
| Kashikar-Zuck, S | 1 |
| Welge, JA | 2 |
| Arnold, LM | 2 |
| Zijlstra, TR | 1 |
| van de Laar, MA | 1 |
| Stratz, T | 1 |
| Varga, B | 1 |
| Müller, W | 1 |
| Marcus, DA | 1 |
| Ozerbil, O | 1 |
| Okudan, N | 1 |
| Gökbel, H | 1 |
| Levendoğlu, F | 1 |
| Laske, C | 1 |
| Stransky, E | 1 |
| Eschweiler, GW | 1 |
| Klein, R | 1 |
| Wittorf, A | 1 |
| Leyhe, T | 1 |
| Richartz, E | 1 |
| Köhler, N | 1 |
| Bartels, M | 1 |
| Buchkremer, G | 1 |
| Schott, K | 1 |
| Zucker, DR | 1 |
| Ruthazer, R | 2 |
| Schmid, CH | 1 |
| Feuer, JM | 1 |
| Fischer, PA | 1 |
| Kieval, RI | 1 |
| Mogavero, N | 1 |
| Rapoport, RJ | 1 |
| Selker, HP | 1 |
| Stotsky, SA | 1 |
| Winston, E | 1 |
| Goldenberg, DL | 1 |
| Onat, AM | 1 |
| Oztürk, MA | 1 |
| Ozçakar, L | 1 |
| Ureten, K | 1 |
| Kaymak, SU | 1 |
| Kiraz, S | 1 |
| Ertenli, I | 1 |
| Calgüneri, M | 1 |
| Wolfe, F | 1 |
| Cathey, MA | 1 |
| Hawley, DJ | 1 |
| Cantini, F | 1 |
| Bellandi, F | 1 |
| Niccoli, L | 1 |
| Di Munno, O | 1 |
| Goldenberg, D | 1 |
| Mayskiy, M | 1 |
| Mossey, C | 1 |
| Schmid, C | 1 |
| Johnson, SP | 1 |
| Nerhood, RC | 1 |
| McGurk, C | 1 |
| Wilson, D | 1 |
| Henry, W | 1 |
| Hess, EV | 1 |
| Hudson, JI | 1 |
| Berno, SE | 1 |
| Keck, PE | 1 |
| O'Malley, PG | 1 |
| Finestone, DH | 1 |
| Ober, SK | 1 |
| Geller, SA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combining N-of-1 Trials to Assess Fibromyalgia Therapies[NCT00000428] | Phase 4 | 58 participants (Actual) | Interventional | 2000-09-30 | Completed | ||
| Evaluation of the Efficiency of a Therapeutic Education Program in Standardized Thermal Cure for Fibromyalgia Patients[NCT02406313] | 152 participants (Actual) | Interventional | 2015-03-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for fluoxetine and Fibromyalgia
| Article | Year |
|---|---|
Combination pharmacotherapy for the treatment of fibromyalgia in adults.
Topics: 5-Hydroxytryptophan; Acetaminophen; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; A | 2018 |
Selective serotonin reuptake inhibitors for fibromyalgia syndrome.
Topics: Amitriptyline; Citalopram; Fibromyalgia; Fluoxetine; Humans; Melatonin; Musculoskeletal Pain; Paroxe | 2015 |
Current trends in fibromyalgia research.
Topics: Antidepressive Agents; Exercise Therapy; Fibromyalgia; Fluoxetine; Humans; Randomized Controlled Tri | 2003 |
Diagnosing fibromyalgia.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Cognitive Behavioral Therapy; Fibromyalgia; Fluoxetine; Hum | 2001 |
8 trials available for fluoxetine and Fibromyalgia
| Article | Year |
|---|---|
Adjuvant use of melatonin for treatment of fibromyalgia.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Fibromyalgia; Fluox | 2011 |
An exploratory, open trial of fluoxetine treatment of juvenile fibromyalgia.
Topics: Adolescent; Age of Onset; Female; Fibromyalgia; Fluoxetine; Humans; Pilot Projects; Selective Seroto | 2012 |
[The influence of depression on the effect of Tropisetron in the therapy of fibromyalgia].
Topics: Adjustment Disorders; Administration, Oral; Adult; Amitriptyline; Depressive Disorder; Drug Therapy, | 2003 |
Comparison of the effects of two antidepressants on exercise performance of the female patients with fibromyalgia.
Topics: Adult; Amitriptyline; Antidepressive Agents; Cross-Over Studies; Double-Blind Method; Exercise Test; | 2006 |
A double-blind placebo controlled trial of fluoxetine in fibromyalgia.
Topics: Adult; Aged; Anxiety; Depression; Double-Blind Method; Female; Fibromyalgia; Fluoxetine; Humans; Mid | 1994 |
[Fluoxetin combined with cyclobenzaprine in the treatment of fibromyalgia].
Topics: Adult; Amitriptyline; Drug Therapy, Combination; Female; Fibromyalgia; Fluoxetine; Humans; Middle Ag | 1994 |
A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia.
Topics: Adolescent; Adult; Amitriptyline; Analysis of Variance; Double-Blind Method; Drug Therapy, Combinati | 1996 |
A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia.
Topics: Adult; Aged; Double-Blind Method; Educational Status; Female; Fibromyalgia; Fluoxetine; Humans; Midd | 2002 |
11 other studies available for fluoxetine and Fibromyalgia
| Article | Year |
|---|---|
Sleep architecture is altered in the reserpine-induced fibromyalgia model in ovariectomized rats.
Topics: Animals; Disease Models, Animal; Female; Fibromyalgia; Fluoxetine; Hyperalgesia; Ovariectomy; Pain; | 2019 |
Fibromyalgia remains a controversial medical enigma.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents, Second-Generation; Drug Therapy, Com | 2008 |
The lack of a placebo effect in a trial of fluoxetine in the treatment of fibromyalgia.
Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Second-Generation; Female; Fibromyalgia | 2002 |
Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depressive Disorder, | 2007 |
Lessons learned combining N-of-1 trials to assess fibromyalgia therapies.
Topics: Adult; Amitriptyline; Antidepressive Agents; Cross-Over Studies; Double-Blind Method; Drug Therapy, | 2006 |
Selective serotonin reuptake inhibitors reduce the attack frequency in familial mediterranean Fever.
Topics: Acute-Phase Reaction; Adolescent; Adult; Blood Sedimentation; C-Reactive Protein; Colchicine; Depres | 2007 |
Fluoxetine and amitriptyline in the treatment of fibromyalgia.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Double-Blind Method; Drug Therap | 1997 |
Fluoxetine and pregnancy a safe mix?
Topics: Depression; Female; Fibromyalgia; Fluoxetine; Humans; Pregnancy; Pregnancy Complications; Safety; Se | 1998 |
Treatment trials of unexplained symptom syndromes: time for larger and longer trials to address the complexities.
Topics: Female; Fibromyalgia; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Selective Serotonin | 2002 |
Fluoxetine and fibromyalgia.
Topics: Adult; Female; Fibromyalgia; Fluoxetine; Humans; Middle Aged | 1990 |
Treatment of fibrositis with fluoxetine hydrochloride (Prozac).
Topics: Adult; Female; Fibromyalgia; Fluoxetine; Humans | 1989 |