Page last updated: 2024-10-27

fluoxetine and Fatigue Syndrome, Chronic

fluoxetine has been researched along with Fatigue Syndrome, Chronic in 12 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)

Research Excerpts

ExcerptRelevanceReference
"Bupropion responders were more likely to have trough blood levels above 30 ng/ml (chi 2 = 3."1.28Bupropion treatment of fluoxetine-resistant chronic fatigue syndrome. ( Brickman, A; Goodnick, PJ; Klimas, NG; Sandoval, R, 1992)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (83.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pardini, M1
Guida, S1
Primavera, A1
Krueger, F1
Cocito, L1
Gialloreti, LE1
Singh, A1
Garg, V1
Gupta, S1
Kulkarni, SK1
Hickie, I1
Wilson, A1
Vercoulen, JH1
Swanink, CM1
Zitman, FG1
Vreden, SG1
Hoofs, MP1
Fennis, JF1
Galama, JM1
van der Meer, JW1
Bleijenberg, G1
Cleare, AJ1
Wessely, SC1
Sharma, A1
Kendall, MJ1
Oyebode, F1
Jones, D1
Lynch, S2
Seth, R1
Wearden, AJ1
Morriss, RK1
Mullis, R1
Strickland, PL1
Pearson, DJ1
Appleby, L1
Campbell, IT1
Morris, JA1
Deale, A1
Chalder, T1
Wessely, S1
Fraser, J1
Everitt, BS1
Goodnick, PJ1
Sandoval, R1
Brickman, A1
Klimas, NG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Shanghai University of Traditional Chinese Medicine[NCT03496961]135 participants (Anticipated)Interventional2018-12-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for fluoxetine and Fatigue Syndrome, Chronic

ArticleYear
Amisulpride vs. fluoxetine treatment of chronic fatigue syndrome: a pilot study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2011, Volume: 21, Issue:3

    Topics: Amisulpride; Dopamine Antagonists; Fatigue Syndrome, Chronic; Female; Fluoxetine; Humans; Male; Pilo

2011
Randomised, double-blind, placebo-controlled study of fluoxetine in chronic fatigue syndrome.
    Lancet (London, England), 1996, Mar-30, Volume: 347, Issue:9005

    Topics: Adult; Antidepressive Agents, Second-Generation; Case-Control Studies; Depressive Disorder; Double-B

1996
Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome.
    The British journal of psychiatry : the journal of mental science, 1998, Volume: 172

    Topics: Adult; Antidepressive Agents, Second-Generation; Combined Modality Therapy; Double-Blind Method; Exe

1998

Other Studies

9 other studies available for fluoxetine and Fatigue Syndrome, Chronic

ArticleYear
Role of antioxidants in chronic fatigue syndrome in mice.
    Indian journal of experimental biology, 2002, Volume: 40, Issue:11

    Topics: Animals; Antioxidants; Brain; Carbazoles; Carvedilol; Catalase; Disease Models, Animal; Fatigue Synd

2002
A catecholamine model of fatigue.
    The British journal of psychiatry : the journal of mental science, 1994, Volume: 165, Issue:2

    Topics: Activities of Daily Living; Adolescent; Adult; Aged; Benzamides; Brain; Catecholamines; Depressive D

1994
Fluoxetine and chronic fatigue syndrome.
    Lancet (London, England), 1996, Jun-22, Volume: 347, Issue:9017

    Topics: Antidepressive Agents, Second-Generation; Fatigue Syndrome, Chronic; Fluoxetine; Humans; Somatoform

1996
Fluoxetine and chronic fatigue syndrome.
    Lancet (London, England), 1996, Jun-22, Volume: 347, Issue:9017

    Topics: Antidepressive Agents, Second-Generation; Fatigue Syndrome, Chronic; Fluoxetine; Humans

1996
Fluoxetine and chronic fatigue syndrome.
    Lancet (London, England), 1996, Jun-22, Volume: 347, Issue:9017

    Topics: Antidepressive Agents, Second-Generation; Fatigue Syndrome, Chronic; Fluoxetine; Humans; Placebo Eff

1996
Commentary on: randomised, double-blind, placebo-controlled trial of fluoxetine and graded exercise for chronic fatigue syndrome.
    The British journal of psychiatry : the journal of mental science, 1998, Volume: 172

    Topics: Adult; Antidepressive Agents, Second-Generation; Combined Modality Therapy; Exercise Therapy; Fatigu

1998
Fluoxetine and graded exercise in chronic fatigue syndrome.
    The British journal of psychiatry : the journal of mental science, 1998, Volume: 173

    Topics: Antidepressive Agents, Second-Generation; Combined Modality Therapy; Exercise Therapy; Fatigue Syndr

1998
Analysis of drop-out data in treatment trials.
    The British journal of psychiatry : the journal of mental science, 1998, Volume: 173

    Topics: Data Interpretation, Statistical; Exercise Therapy; Fatigue Syndrome, Chronic; Fluoxetine; Humans; P

1998
Bupropion treatment of fluoxetine-resistant chronic fatigue syndrome.
    Biological psychiatry, 1992, Nov-01, Volume: 32, Issue:9

    Topics: Adult; Bupropion; Depressive Disorder; Fatigue Syndrome, Chronic; Female; Fluoxetine; Follow-Up Stud

1992