fluoxetine has been researched along with Familial Primary Pulmonary Hypertension in 3 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Familial Primary Pulmonary Hypertension: Familial or idiopathic hypertension in the PULMONARY CIRCULATION which is not secondary to other disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of the selective serotonin reuptake inhibitor (SSRI) fluoxetine on extracellular matrix (ECM) remodeling of the pulmonary artery and inflammation of the lungs in pulmonary arterial hypertension (PAH) induced by monocrotaline in rats." | 7.77 | Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats. ( Han, DD; Li, XQ; Wang, HL; Wang, HM; Yang, CG; Zhang, XH, 2011) |
| "To investigate the effects of the selective serotonin reuptake inhibitor (SSRI) fluoxetine on extracellular matrix (ECM) remodeling of the pulmonary artery and inflammation of the lungs in pulmonary arterial hypertension (PAH) induced by monocrotaline in rats." | 3.77 | Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats. ( Han, DD; Li, XQ; Wang, HL; Wang, HM; Yang, CG; Zhang, XH, 2011) |
| "Fluoxetine was administered by gastric gavage once a day for 21 d." | 1.38 | Fluoxetine inhibits monocrotaline-induced pulmonary arterial remodeling involved in inhibition of RhoA-Rho kinase and Akt signalling pathways in rats. ( Bai, Y; Liu, M; Sun, YX; Wang, HL; Wang, HM; Wang, Y; Zhang, XH, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, XQ | 1 |
| Wang, HM | 3 |
| Yang, CG | 1 |
| Zhang, XH | 3 |
| Han, DD | 1 |
| Wang, HL | 3 |
| Liu, M | 2 |
| Wang, Y | 2 |
| Bai, Y | 2 |
| Sun, YX | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fluoxetine to Reduce Hospitalization From COVID-19 Infection (FloR COVID-19)[NCT04570449] | Early Phase 1 | 0 participants (Actual) | Interventional | 2020-11-30 | Withdrawn (stopped due to Study timeline is not feasible) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for fluoxetine and Familial Primary Pulmonary Hypertension
| Article | Year |
|---|---|
Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats.
Topics: Animals; Cytokines; Disease Models, Animal; Extracellular Matrix; Familial Primary Pulmonary Hyperte | 2011 |
Fluoxetine attenuates chronic methamphetamine-induced pulmonary arterial remodelling: possible involvement of serotonin transporter and serotonin 1B receptor.
Topics: Amphetamine-Related Disorders; Animals; Antidepressive Agents, Second-Generation; Down-Regulation; F | 2013 |
Fluoxetine inhibits monocrotaline-induced pulmonary arterial remodeling involved in inhibition of RhoA-Rho kinase and Akt signalling pathways in rats.
Topics: Airway Remodeling; Animals; Disease Models, Animal; Down-Regulation; Familial Primary Pulmonary Hype | 2012 |