Page last updated: 2024-10-27

fluoxetine and Epilepsy, Tonic-Clonic

fluoxetine has been researched along with Epilepsy, Tonic-Clonic in 9 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine is a relatively new antidepressant, reported to have minimal side-effects."6.38Seizures associated with fluoxetine therapy. ( Prasher, VP, 1993)
"Fluoxetine is a relatively new antidepressant, reported to have minimal side-effects."2.38Seizures associated with fluoxetine therapy. ( Prasher, VP, 1993)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (88.89)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Compton, R1
Spiller, HA1
Bosse, GM1
Prasher, VP1
Levine, R1
Kenin, M1
Hoffman, JS1
Day-Knepple, E1
Spina, E1
Avenoso, A1
Pollicino, AM1
Caputi, AP1
Fazio, A1
Pisani, F1
Shad, MU1
Preskorn, SH2
Grady, TA1
Pigott, TA1
L'Heureux, F1
Murphy, DL1
Hargrave, R1
Martinez, D1
Bernstein, AJ1
Picker, W1
Lerman, A1
Hajal, F1
Beber, JH1
Faul, JC1
Hirschfeld, RM1

Reviews

1 review available for fluoxetine and Epilepsy, Tonic-Clonic

ArticleYear
Seizures associated with fluoxetine therapy.
    Seizure, 1993, Volume: 2, Issue:4

    Topics: Adult; Depressive Disorder; Epilepsy, Tonic-Clonic; Female; Fluoxetine; Humans; Psychotic Disorders;

1993

Trials

1 trial available for fluoxetine and Epilepsy, Tonic-Clonic

ArticleYear
Carbamazepine coadministration with fluoxetine or fluvoxamine.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:3

    Topics: Adult; Carbamazepine; Depression; Drug Interactions; Drug Therapy, Combination; Epilepsy, Complex Pa

1993

Other Studies

7 other studies available for fluoxetine and Epilepsy, Tonic-Clonic

ArticleYear
Fatal fluoxetine ingestion with postmortem blood concentrations.
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:4

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bradycardia; Child, Preschool; Dia

2005
Grand mal seizures associated with the use of fluoxetine.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Epilepsy, Tonic-Clonic; Female; Fluoxetine; Humans; Male; Middle Aged

1994
Drug-drug interaction in reverse: possible loss of phenytoin efficacy as a result of fluoxetine discontinuation.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:5

    Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy, Tonic-Clonic; Fluoxetine; Humans; Male; Phenyto

1999
Seizure associated with fluoxetine and adjuvant buspirone therapy.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:1

    Topics: Adult; Buspirone; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Fluoxetine; Humans; Male; Obses

1992
Fluoxetine-induced seizures.
    Psychosomatics, 1992,Spring, Volume: 33, Issue:2

    Topics: Adult; Depressive Disorder; Epilepsy, Tonic-Clonic; Female; Fluoxetine; Humans; Male; Middle Aged; S

1992
Potential interaction of LSD and fluoxetine.
    The American journal of psychiatry, 1992, Volume: 149, Issue:6

    Topics: Adolescent; Drug Interactions; Epilepsy, Tonic-Clonic; Fluoxetine; Humans; Lysergic Acid Diethylamid

1992
Serious adverse effects of combining fluoxetine and tricyclic antidepressants.
    The American journal of psychiatry, 1990, Volume: 147, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Delirium; Drug Interactions; Drug Therapy, Combinatio

1990