Page last updated: 2024-10-27

fluoxetine and Disruptive, Impulse Control, and Conduct Disorders

fluoxetine has been researched along with Disruptive, Impulse Control, and Conduct Disorders in 17 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Disruptive, Impulse Control, and Conduct Disorders: Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.

Research Excerpts

ExcerptRelevanceReference
"We describe three patients with concurrent DSM-III-R kleptomania and bulimia nervosa who all demonstrated a partial or complete response of both bulimic and kleptomanic symptoms to fluoxetine, trazodone, or tranylcypromine."5.06Pharmacological treatment of kleptomania and bulimia nervosa. ( Hudson, JI; Keck, PE; McElroy, SL; Pope, HG, 1989)
"In the treatment of kleptomania, only naltrexone was effective."2.82Pharmacotherapy of impulse control disorders: A systematic review. ( Maaz, M; Naidoo, Y; Naufal, R; Tahir, R; Tahir, T; Wong, MM, 2022)
"Fluoxetine treatment resulted in a sustained reduction in OAS-M aggression, and OAS-M irritability scores, apparent as early as week 2 (p < ."2.74A double-blind, randomized, placebo-controlled trial of fluoxetine in patients with intermittent explosive disorder. ( Coccaro, EF; Kavoussi, RJ; Lee, RJ, 2009)
"Fluoxetine was significantly superior to placebo in the treatment of skin picking according to two of the three measures for the completer analysis and to one of the three measures for the intent-to-treat analysis."2.68A double-blind trial of fluoxetine in pathologic skin picking. ( Gross, S; Hollander, E; Islam, N; Schmeidler, J; Simeon, D; Stein, DJ, 1997)
"Kleptomania is an impulse control disorder characterized by a recurrent failure to resist the impulse to steal worthless objects that are not needed for personal use."1.38Naltrexone treatment of kleptomania: a case report. ( Belkız Güngör, B; Çetinay Aydın, P; Gülseren, L, 2012)
"Asperger's disorder was diagnosed after we reconsidered the relationship between the schizoid psychopathy in childhood and the stealing behaviours which occurred in adolescence."1.32Asperger's disorder: a case report of repeated stealing and the collecting behaviours of an adolescent patient. ( Chen, CC; Chen, PS; Chen, SJ; Lo, HY; Yang, YK; Yeh, TL, 2003)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's6 (35.29)18.2507
2000's6 (35.29)29.6817
2010's3 (17.65)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Tahir, T1
Wong, MM1
Maaz, M1
Naufal, R1
Tahir, R1
Naidoo, Y1
Coccaro, EF3
Lee, R1
Breen, EC1
Irwin, MR1
Lee, RJ1
Kavoussi, RJ1
George, DT1
Phillips, MJ1
Lifshitz, M1
Lionetti, TA1
Spero, DE1
Ghassemzedeh, N1
Doty, L1
Umhau, JC1
Rawlings, RR1
Çetinay Aydın, P1
Belkız Güngör, B1
Gülseren, L1
Chen, PS1
Chen, SJ1
Yang, YK1
Yeh, TL1
Chen, CC1
Lo, HY1
Christensen, RC1
Bragulat, V1
Paillère-Martinot, ML1
Artiges, E1
Frouin, V1
Poline, JB1
Martinot, JL1
Schupak, C1
Kmetz, GF1
McElroy, SL2
Collins, DJ1
Kindler, S1
Dannon, PN1
Iancu, I1
Sasson, Y1
Zohar, J1
Simeon, D1
Stein, DJ1
Gross, S1
Islam, N1
Schmeidler, J1
Hollander, E1
Velazquez, L1
Ward-Chene, L1
Loosigian, SR1
Burstein, A1
Astill, JL1
Herbert, JL1
Schut, AG1
Stout, RJ1
Keck, PE1
Pope, HG1
Hudson, JI1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Pimavanserin on Aggression and Social Cognition.[NCT05895513]Phase 235 participants (Anticipated)Interventional2024-01-31Not yet recruiting
The Effect of Fluoxetine on Measures of Domestic Violence[NCT00011765]Phase 2104 participants (Actual)Interventional2001-02-22Completed
Escitalopram for the Treatment of Self-Injurious Skin Picking[NCT00115011]Phase 430 participants (Actual)Interventional2002-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for fluoxetine and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
Pharmacotherapy of impulse control disorders: A systematic review.
    Psychiatry research, 2022, Volume: 311

    Topics: Antidepressive Agents; Disruptive, Impulse Control, and Conduct Disorders; Fluoxetine; Humans; Valpr

2022

Trials

5 trials available for fluoxetine and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
Inflammatory markers and chronic exposure to fluoxetine, divalproex, and placebo in intermittent explosive disorder.
    Psychiatry research, 2015, Oct-30, Volume: 229, Issue:3

    Topics: Adult; Aggression; Biomarkers; C-Reactive Protein; Disruptive, Impulse Control, and Conduct Disorder

2015
A double-blind, randomized, placebo-controlled trial of fluoxetine in patients with intermittent explosive disorder.
    The Journal of clinical psychiatry, 2009, Apr-21, Volume: 70, Issue:5

    Topics: Adult; Diagnostic and Statistical Manual of Mental Disorders; Disruptive, Impulse Control, and Condu

2009
Fluoxetine treatment of alcoholic perpetrators of domestic violence: a 12-week, double-blind, randomized, placebo-controlled intervention study.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:1

    Topics: Aggression; Alcoholics Anonymous; Alcoholism; Anger; Cognitive Behavioral Therapy; Combined Modality

2011
A double-blind trial of fluoxetine in pathologic skin picking.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:8

    Topics: Adult; Confounding Factors, Epidemiologic; Disruptive, Impulse Control, and Conduct Disorders; Doubl

1997
Pharmacological treatment of kleptomania and bulimia nervosa.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:5

    Topics: Adult; Bulimia; Clinical Trials as Topic; Disruptive, Impulse Control, and Conduct Disorders; Drug T

1989

Other Studies

11 other studies available for fluoxetine and Disruptive, Impulse Control, and Conduct Disorders

ArticleYear
Naltrexone treatment of kleptomania: a case report.
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2012,Winter, Volume: 23, Issue:4

    Topics: Antidepressive Agents, Second-Generation; Cognitive Behavioral Therapy; Depressive Disorder; Diagnos

2012
Asperger's disorder: a case report of repeated stealing and the collecting behaviours of an adolescent patient.
    Acta psychiatrica Scandinavica, 2003, Volume: 107, Issue:1

    Topics: Adult; Asperger Syndrome; Disruptive, Impulse Control, and Conduct Disorders; Fluoxetine; Humans; Ma

2003
Olanzapine augmentation of fluoxetine in the treatment of pathological skin picking.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2004, Volume: 49, Issue:11

    Topics: Benzodiazepines; Disruptive, Impulse Control, and Conduct Disorders; Drug Therapy, Combination; Fema

2004
Dopaminergic function in depressed patients with affective flattening or with impulsivity: [18F]fluoro-L-dopa positron emission tomography study with voxel-based analysis.
    Psychiatry research, 2007, Feb-28, Volume: 154, Issue:2

    Topics: Adult; Affect; Biogenic Monoamines; Brain Stem; Caudate Nucleus; Cyclohexanols; Depressive Disorder,

2007
Case report: lamotrigine/fluoxetine combination in the treatment of compulsive sexual behavior.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Aug-15, Volume: 31, Issue:6

    Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Compulsive Behavior; Disruptive, I

2007
Response of kleptomania and mixed mania to valproate.
    The American journal of psychiatry, 1997, Volume: 154, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar Disorder; Comorbidity; Di

1997
Emergence of kleptomania during treatment for depression with serotonin selective reuptake inhibitors.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:2

    Topics: Aged; Antidepressive Agents, Second-Generation; Depressive Disorder; Disruptive, Impulse Control, an

1997
Fluoxetine in the treatment of self-mutilating behavior.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2000, Volume: 39, Issue:7

    Topics: Adolescent; Child; Child, Preschool; Disruptive, Impulse Control, and Conduct Disorders; Fluoxetine;

2000
Fluoxetine-lithium treatment for kleptomania.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:1

    Topics: Adult; Disruptive, Impulse Control, and Conduct Disorders; Drug Therapy, Combination; Female; Fluoxe

1992
Fluoxetine treatment of impulsive aggression in DSM-III-R personality disorder patients.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:5

    Topics: Adult; Aggression; Antisocial Personality Disorder; Borderline Personality Disorder; Disruptive, Imp

1990
Fluoxetine for the treatment of compulsive facial picking.
    The American journal of psychiatry, 1990, Volume: 147, Issue:3

    Topics: Adult; Disruptive, Impulse Control, and Conduct Disorders; Female; Fluoxetine; Humans; Obsessive-Com

1990