fluoxetine has been researched along with Diffuse Myofascial Pain Syndrome in 23 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As described elsewhere the oral administration of 5 mg of the 5-HT3-receptor-antagonist Tropisetron in fibromyalgia exhibited less amelioration of pain in patients with a depression in comparison to patients without depression." | 9.10 | [The influence of depression on the effect of Tropisetron in the therapy of fibromyalgia]. ( Müller, W; Stratz, T; Varga, B, 2003) |
| "To assess the efficacy of fluoxetine in the treatment of patients with fibromyalgia." | 9.10 | A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. ( Arnold, LM; Berno, SE; Hess, EV; Hudson, JI; Keck, PE; Welge, JA, 2002) |
| "To study the effect of fluoxetine (FL) and amitriptyline (AM), alone and in combination, in patients with fibromyalgia (FM)." | 9.08 | A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia. ( Goldenberg, D; Mayskiy, M; Mossey, C; Ruthazer, R; Schmid, C, 1996) |
| "The aim of this study is to evaluate the effectiveness of fluoxetin associated with cyclobenzaprine vs cyclobenzaprine in the treatment of fibromyalgia." | 9.07 | [Fluoxetin combined with cyclobenzaprine in the treatment of fibromyalgia]. ( Bellandi, F; Cantini, F; Di Munno, O; Niccoli, L, 1994) |
| "Peak power and fatigue index increased, and VO(2max) and VT did not change with both fluoxetine and amitriptyline." | 5.12 | Comparison of the effects of two antidepressants on exercise performance of the female patients with fibromyalgia. ( Gökbel, H; Levendoğlu, F; Okudan, N; Ozerbil, O, 2006) |
| "As described elsewhere the oral administration of 5 mg of the 5-HT3-receptor-antagonist Tropisetron in fibromyalgia exhibited less amelioration of pain in patients with a depression in comparison to patients without depression." | 5.10 | [The influence of depression on the effect of Tropisetron in the therapy of fibromyalgia]. ( Müller, W; Stratz, T; Varga, B, 2003) |
| "To assess the efficacy of fluoxetine in the treatment of patients with fibromyalgia." | 5.10 | A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia. ( Arnold, LM; Berno, SE; Hess, EV; Hudson, JI; Keck, PE; Welge, JA, 2002) |
| "To study the effect of fluoxetine (FL) and amitriptyline (AM), alone and in combination, in patients with fibromyalgia (FM)." | 5.08 | A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia. ( Goldenberg, D; Mayskiy, M; Mossey, C; Ruthazer, R; Schmid, C, 1996) |
| "The aim of this study is to evaluate the effectiveness of fluoxetin associated with cyclobenzaprine vs cyclobenzaprine in the treatment of fibromyalgia." | 5.07 | [Fluoxetin combined with cyclobenzaprine in the treatment of fibromyalgia]. ( Bellandi, F; Cantini, F; Di Munno, O; Niccoli, L, 1994) |
| "Familial Mediterranean Fever (FMF) is characterized by recurrent acute attacks of fever and serositis, and colchicine is the primary treatment." | 3.74 | Selective serotonin reuptake inhibitors reduce the attack frequency in familial mediterranean Fever. ( Calgüneri, M; Ertenli, I; Kaymak, SU; Kiraz, S; Onat, AM; Ozçakar, L; Oztürk, MA; Ureten, K, 2007) |
| "Community- and center-based rheumatologists enrolled patients with fibromyalgia syndrome in randomized, double-blind, multi-crossover, N-of-1 trials comparing amitriptyline and the combination amitriptyline and fluoxetine." | 3.73 | Lessons learned combining N-of-1 trials to assess fibromyalgia therapies. ( Feuer, JM; Fischer, PA; Goldenberg, DL; Kieval, RI; Mogavero, N; Rapoport, RJ; Ruthazer, R; Schmid, CH; Selker, HP; Stotsky, SA; Winston, E; Zucker, DR, 2006) |
| "Fibromyalgia is a chronic widespread pain condition affecting millions of people worldwide." | 2.58 | Combination pharmacotherapy for the treatment of fibromyalgia in adults. ( Gilron, I; Moore, RA; Shum, B; Thorpe, J; Wiffen, PJ, 2018) |
| "Fibromyalgia is a clinically well-defined chronic condition with a biopsychosocial aetiology." | 2.52 | Selective serotonin reuptake inhibitors for fibromyalgia syndrome. ( Cantrell, SE; Häuser, W; Nishishinya, MB; Urrútia, G; Walitt, B, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 11 (47.83) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hernandez-Leon, A | 1 |
| Fernández-Guasti, A | 1 |
| Martínez, A | 1 |
| Pellicer, F | 1 |
| González-Trujano, ME | 1 |
| Thorpe, J | 1 |
| Shum, B | 1 |
| Moore, RA | 1 |
| Wiffen, PJ | 1 |
| Gilron, I | 1 |
| Walitt, B | 1 |
| Urrútia, G | 1 |
| Nishishinya, MB | 1 |
| Cantrell, SE | 1 |
| Häuser, W | 1 |
| Adams, SM | 1 |
| Hussain, SA | 1 |
| Al-Khalifa, II | 1 |
| Jasim, NA | 1 |
| Gorial, FI | 1 |
| Mariutto, EN | 1 |
| Stanford, SB | 1 |
| Kashikar-Zuck, S | 1 |
| Welge, JA | 2 |
| Arnold, LM | 2 |
| Zijlstra, TR | 1 |
| van de Laar, MA | 1 |
| Stratz, T | 1 |
| Varga, B | 1 |
| Müller, W | 1 |
| Marcus, DA | 1 |
| Ozerbil, O | 1 |
| Okudan, N | 1 |
| Gökbel, H | 1 |
| Levendoğlu, F | 1 |
| Laske, C | 1 |
| Stransky, E | 1 |
| Eschweiler, GW | 1 |
| Klein, R | 1 |
| Wittorf, A | 1 |
| Leyhe, T | 1 |
| Richartz, E | 1 |
| Köhler, N | 1 |
| Bartels, M | 1 |
| Buchkremer, G | 1 |
| Schott, K | 1 |
| Zucker, DR | 1 |
| Ruthazer, R | 2 |
| Schmid, CH | 1 |
| Feuer, JM | 1 |
| Fischer, PA | 1 |
| Kieval, RI | 1 |
| Mogavero, N | 1 |
| Rapoport, RJ | 1 |
| Selker, HP | 1 |
| Stotsky, SA | 1 |
| Winston, E | 1 |
| Goldenberg, DL | 1 |
| Onat, AM | 1 |
| Oztürk, MA | 1 |
| Ozçakar, L | 1 |
| Ureten, K | 1 |
| Kaymak, SU | 1 |
| Kiraz, S | 1 |
| Ertenli, I | 1 |
| Calgüneri, M | 1 |
| Wolfe, F | 1 |
| Cathey, MA | 1 |
| Hawley, DJ | 1 |
| Cantini, F | 1 |
| Bellandi, F | 1 |
| Niccoli, L | 1 |
| Di Munno, O | 1 |
| Goldenberg, D | 1 |
| Mayskiy, M | 1 |
| Mossey, C | 1 |
| Schmid, C | 1 |
| Johnson, SP | 1 |
| Nerhood, RC | 1 |
| McGurk, C | 1 |
| Wilson, D | 1 |
| Henry, W | 1 |
| Hess, EV | 1 |
| Hudson, JI | 1 |
| Berno, SE | 1 |
| Keck, PE | 1 |
| O'Malley, PG | 1 |
| Finestone, DH | 1 |
| Ober, SK | 1 |
| Geller, SA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combining N-of-1 Trials to Assess Fibromyalgia Therapies[NCT00000428] | Phase 4 | 58 participants (Actual) | Interventional | 2000-09-30 | Completed | ||
| Evaluation of the Efficiency of a Therapeutic Education Program in Standardized Thermal Cure for Fibromyalgia Patients[NCT02406313] | 152 participants (Actual) | Interventional | 2015-03-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for fluoxetine and Diffuse Myofascial Pain Syndrome
| Article | Year |
|---|---|
Combination pharmacotherapy for the treatment of fibromyalgia in adults.
Topics: 5-Hydroxytryptophan; Acetaminophen; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; A | 2018 |
Selective serotonin reuptake inhibitors for fibromyalgia syndrome.
Topics: Amitriptyline; Citalopram; Fibromyalgia; Fluoxetine; Humans; Melatonin; Musculoskeletal Pain; Paroxe | 2015 |
Current trends in fibromyalgia research.
Topics: Antidepressive Agents; Exercise Therapy; Fibromyalgia; Fluoxetine; Humans; Randomized Controlled Tri | 2003 |
Diagnosing fibromyalgia.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Cognitive Behavioral Therapy; Fibromyalgia; Fluoxetine; Hum | 2001 |
8 trials available for fluoxetine and Diffuse Myofascial Pain Syndrome
| Article | Year |
|---|---|
Adjuvant use of melatonin for treatment of fibromyalgia.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Fibromyalgia; Fluox | 2011 |
An exploratory, open trial of fluoxetine treatment of juvenile fibromyalgia.
Topics: Adolescent; Age of Onset; Female; Fibromyalgia; Fluoxetine; Humans; Pilot Projects; Selective Seroto | 2012 |
[The influence of depression on the effect of Tropisetron in the therapy of fibromyalgia].
Topics: Adjustment Disorders; Administration, Oral; Adult; Amitriptyline; Depressive Disorder; Drug Therapy, | 2003 |
Comparison of the effects of two antidepressants on exercise performance of the female patients with fibromyalgia.
Topics: Adult; Amitriptyline; Antidepressive Agents; Cross-Over Studies; Double-Blind Method; Exercise Test; | 2006 |
A double-blind placebo controlled trial of fluoxetine in fibromyalgia.
Topics: Adult; Aged; Anxiety; Depression; Double-Blind Method; Female; Fibromyalgia; Fluoxetine; Humans; Mid | 1994 |
[Fluoxetin combined with cyclobenzaprine in the treatment of fibromyalgia].
Topics: Adult; Amitriptyline; Drug Therapy, Combination; Female; Fibromyalgia; Fluoxetine; Humans; Middle Ag | 1994 |
A randomized, double-blind crossover trial of fluoxetine and amitriptyline in the treatment of fibromyalgia.
Topics: Adolescent; Adult; Amitriptyline; Analysis of Variance; Double-Blind Method; Drug Therapy, Combinati | 1996 |
A randomized, placebo-controlled, double-blind, flexible-dose study of fluoxetine in the treatment of women with fibromyalgia.
Topics: Adult; Aged; Double-Blind Method; Educational Status; Female; Fibromyalgia; Fluoxetine; Humans; Midd | 2002 |
11 other studies available for fluoxetine and Diffuse Myofascial Pain Syndrome
| Article | Year |
|---|---|
Sleep architecture is altered in the reserpine-induced fibromyalgia model in ovariectomized rats.
Topics: Animals; Disease Models, Animal; Female; Fibromyalgia; Fluoxetine; Hyperalgesia; Ovariectomy; Pain; | 2019 |
Fibromyalgia remains a controversial medical enigma.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents, Second-Generation; Drug Therapy, Com | 2008 |
The lack of a placebo effect in a trial of fluoxetine in the treatment of fibromyalgia.
Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Second-Generation; Female; Fibromyalgia | 2002 |
Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Depressive Disorder, | 2007 |
Lessons learned combining N-of-1 trials to assess fibromyalgia therapies.
Topics: Adult; Amitriptyline; Antidepressive Agents; Cross-Over Studies; Double-Blind Method; Drug Therapy, | 2006 |
Selective serotonin reuptake inhibitors reduce the attack frequency in familial mediterranean Fever.
Topics: Acute-Phase Reaction; Adolescent; Adult; Blood Sedimentation; C-Reactive Protein; Colchicine; Depres | 2007 |
Fluoxetine and amitriptyline in the treatment of fibromyalgia.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Double-Blind Method; Drug Therap | 1997 |
Fluoxetine and pregnancy a safe mix?
Topics: Depression; Female; Fibromyalgia; Fluoxetine; Humans; Pregnancy; Pregnancy Complications; Safety; Se | 1998 |
Treatment trials of unexplained symptom syndromes: time for larger and longer trials to address the complexities.
Topics: Female; Fibromyalgia; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Selective Serotonin | 2002 |
Fluoxetine and fibromyalgia.
Topics: Adult; Female; Fibromyalgia; Fluoxetine; Humans; Middle Aged | 1990 |
Treatment of fibrositis with fluoxetine hydrochloride (Prozac).
Topics: Adult; Female; Fibromyalgia; Fluoxetine; Humans | 1989 |