Page last updated: 2024-10-27

fluoxetine and Diabetic Neuropathies

fluoxetine has been researched along with Diabetic Neuropathies in 4 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"Amitriptyline reduces the pain caused by peripheral-nerve disease, but treatment is often limited by side effects related to the drug's many pharmacologic actions."9.07Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy. ( Dubner, R; Lynch, SA; Max, MB; Muir, J; Shoaf, SE; Smoller, B, 1992)
"Amitriptyline reduces the pain caused by peripheral-nerve disease, but treatment is often limited by side effects related to the drug's many pharmacologic actions."5.07Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy. ( Dubner, R; Lynch, SA; Max, MB; Muir, J; Shoaf, SE; Smoller, B, 1992)
"In comorbid diabetes mellitus and depression, most evidence supports the use of fluoxetine in control of glucose handling."4.81Use of antidepressants in treatment of comorbid diabetes mellitus and depression as well as in diabetic neuropathy. ( Goodnick, PJ, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdelrahman, SA1
Samak, MA1
Shalaby, SM1
Hearn, L1
Moore, RA1
Derry, S1
Wiffen, PJ1
Phillips, T1
Goodnick, PJ1
Max, MB1
Lynch, SA1
Muir, J1
Shoaf, SE1
Smoller, B1
Dubner, R1

Reviews

2 reviews available for fluoxetine and Diabetic Neuropathies

ArticleYear
Desipramine for neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2014, Sep-23, Issue:9

    Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Pain; Clomipramine; Desip

2014
Use of antidepressants in treatment of comorbid diabetes mellitus and depression as well as in diabetic neuropathy.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2001, Volume: 13, Issue:1

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Blood Glucose; Clinical Trials as T

2001

Trials

1 trial available for fluoxetine and Diabetic Neuropathies

ArticleYear
Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy.
    The New England journal of medicine, 1992, May-07, Volume: 326, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Analgesics; Depression; Desipramine; Diabetic Neuropa

1992

Other Studies

1 other study available for fluoxetine and Diabetic Neuropathies

ArticleYear
Fluoxetine pretreatment enhances neurogenic, angiogenic and immunomodulatory effects of MSCs on experimentally induced diabetic neuropathy.
    Cell and tissue research, 2018, Volume: 374, Issue:1

    Topics: Animals; Diabetic Neuropathies; Fluoxetine; Humans; Immunomodulation; Male; Mesenchymal Stem Cells;

2018