fluoxetine has been researched along with Dementia in 19 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of a possible interaction with pimozide which led to a potentially life threatening bradycardia." | 7.68 | Possible interaction between fluoxetine and pimozide causing sinus bradycardia. ( Ahmed, I; Dagincourt, PG; Miller, LG; Shader, RI, 1993) |
| " TRAZODONE: Studies conducted in patients with Alzheimer's disease, mixed type dementia, or fronto-temporal dementia have shown the efficacy of trazodone for diverse types of symptoms: sadness, emotional disorders, irritability, fear, psychomotor instability, delirant ideas." | 4.82 | [Serotonin reuptake inhibitors in depression of Alzheimer's disease and other dementias]. ( Lebert, F, 2003) |
| " We report a case of a possible interaction with pimozide which led to a potentially life threatening bradycardia." | 3.68 | Possible interaction between fluoxetine and pimozide causing sinus bradycardia. ( Ahmed, I; Dagincourt, PG; Miller, LG; Shader, RI, 1993) |
| "Fluoxetine appears to be an effective and well-tolerated antidepressant in elderly inpatients of varying age, levels of depression, and psychiatric diagnoses." | 2.68 | The use and tolerability of fluoxetine in geropsychiatric inpatients. ( Kunik, ME; Molinari, V; Orengo, CA; Workman, RH, 1996) |
| "Depression is a highly prevalent concomitant of dementia." | 2.40 | Depression and dementia: comorbidities, identification, and treatment. ( Meyers, BS, 1998) |
| "The pattern of myoclonus is unlike previous reported cases and may relate to activation of serotonin 5HT1A receptors (possibly supersensitive in Pick's disease) or to hypodopaminergia." | 1.29 | Reversible intermittent rhythmic myoclonus with fluoxetine in presumed Pick's disease. ( Lauterbach, EC, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 13 (68.42) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kostić, V | 1 |
| Dzoljić, E | 1 |
| Todorović, Z | 1 |
| Mijajlović, M | 1 |
| Svetel, M | 1 |
| Stefanova, E | 1 |
| Dragasević, N | 1 |
| Petrović, I | 1 |
| Milosević, M | 1 |
| Kovacević, I | 1 |
| Miljković, B | 1 |
| Pokrajac, M | 1 |
| Prostran, M | 1 |
| Harper, A | 1 |
| Lebert, F | 1 |
| Le Ber, I | 1 |
| Dubois, B | 1 |
| Preskorn, SH | 1 |
| Anderson, IM | 1 |
| Scott, K | 1 |
| Harborne, G | 1 |
| Friedman, EH | 1 |
| Lauterbach, EC | 2 |
| Ahmed, I | 1 |
| Dagincourt, PG | 1 |
| Miller, LG | 1 |
| Shader, RI | 1 |
| Orengo, CA | 1 |
| Kunik, ME | 1 |
| Molinari, V | 1 |
| Workman, RH | 1 |
| Omar, SJ | 1 |
| Robinson, D | 1 |
| Davies, HD | 1 |
| Miller, TP | 1 |
| Tinklenberg, JR | 1 |
| Flint, AJ | 1 |
| Rifat, SL | 1 |
| Auer, SR | 1 |
| Monteiro, IM | 1 |
| Reisberg, B | 1 |
| Swartz, JR | 1 |
| Miller, BL | 1 |
| Lesser, IM | 1 |
| Darby, AL | 1 |
| Anderson, J | 1 |
| Compton, SA | 1 |
| Strachan, J | 1 |
| Shepherd, J | 1 |
| Meyers, BS | 1 |
| Schweri, MM | 1 |
| Sobin, P | 1 |
| Schneider, L | 1 |
| McDermott, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Controlled, Randomized, Double-Blind Trial of Sertraline in Patients With Frontal Lobe Dementia (FLD)[NCT00001777] | Phase 1 | 30 participants | Interventional | 1997-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fluoxetine and Dementia
| Article | Year |
|---|---|
[Serotonin reuptake inhibitors in depression of Alzheimer's disease and other dementias].
Topics: Aged; Alzheimer Disease; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Clinical Tri | 2003 |
[Frontotemporal dementia].
Topics: Adenosine Triphosphatases; Aged; Aged, 80 and over; Alzheimer Disease; Amyotrophic Lateral Sclerosis | 2007 |
Depression and dementia: comorbidities, identification, and treatment.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cog | 1998 |
4 trials available for fluoxetine and Dementia
| Article | Year |
|---|---|
Fluoxetine does not impair motor function in patients with Parkinson's disease: correlation between mood and motor functions with plasma concentrations of fluoxetine/norfluoxetine.
Topics: Activities of Daily Living; Affect; Antidepressive Agents, Second-Generation; Dementia; Depression; | 2012 |
The use and tolerability of fluoxetine in geropsychiatric inpatients.
Topics: Age Factors; Aged; Antipsychotic Agents; Dementia; Depressive Disorder; Drug Therapy, Combination; F | 1996 |
Behavioral symptoms in dementia: community-based research.
Topics: Aged; Alzheimer Disease; Ambulatory Care; Antipsychotic Agents; Dementia; Double-Blind Method; Femal | 1996 |
Frontotemporal dementia: treatment response to serotonin selective reuptake inhibitors.
Topics: 1-Naphthylamine; Adult; Compulsive Behavior; Dementia; Depressive Disorder; Female; Fluoxetine; Fron | 1997 |
12 other studies available for fluoxetine and Dementia
| Article | Year |
|---|---|
What is best for the patient?
Topics: Aged; Anxiety Disorders; Cardiovascular Diseases; Dementia; Evidence-Based Medicine; Fluoxetine; Ger | 2003 |
Multiple medication use presenting as Parkinson's dementia complex: a message from Titanic.
Topics: Aged; Anti-Infective Agents; Antiparkinson Agents; Antipsychotic Agents; Bacteriuria; Ciprofloxacin; | 2008 |
Serotonin and depression in frontal lobe dementia.
Topics: Adult; Combined Modality Therapy; Dementia; Depressive Disorder; Drug Therapy, Combination; Electroc | 1995 |
Re: Bradycardia and somnolence after adding fluoxetine to pimozide regimen.
Topics: Aged; Bradycardia; Brain Stem; Cerebral Cortex; Dementia; Dominance, Cerebral; Drug Synergism; Fluox | 1994 |
Reversible intermittent rhythmic myoclonus with fluoxetine in presumed Pick's disease.
Topics: Affective Disorders, Psychotic; Brain; Dementia; Dose-Response Relationship, Drug; Electroencephalog | 1994 |
Possible interaction between fluoxetine and pimozide causing sinus bradycardia.
Topics: Aged; Arrhythmia, Sinus; Bradycardia; Delusions; Dementia; Depressive Disorder; Dose-Response Relati | 1993 |
Fluoxetine and visual hallucinations in dementia.
Topics: Aged; Alzheimer Disease; Antidepressive Agents, Second-Generation; Dementia; Depressive Disorder; Dr | 1995 |
The effect of sequential antidepressant treatment on geriatric depression.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Clinical Protocols; Combined Modality Therapy; Demen | 1996 |
Fluoxetine induced bradycardia in presenile dementia.
Topics: Aged; Alzheimer Disease; Antidepressive Agents, Second-Generation; Bradycardia; Dementia; Fluoxetine | 1997 |
Hyponatraemia associated with the use of selective serotonin re-uptake inhibitors.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Dementia; Depressive Disorder; Dr | 1998 |
Amelioration of pseudobulbar affect by fluoxetine: possible alteration of dopamine-related pathophysiology by a selective serotonin reuptake inhibitor.
Topics: Affect; Caudate Nucleus; Dementia; Fluoxetine; Humans; Male; Middle Aged; Neurocognitive Disorders; | 1991 |
Fluoxetine in the treatment of agitated dementia.
Topics: Aggression; Dementia; Fluoxetine; Humans; Male; Middle Aged; Psychomotor Agitation | 1989 |