Page last updated: 2024-10-27

fluoxetine and Delayed Effects, Prenatal Exposure

fluoxetine has been researched along with Delayed Effects, Prenatal Exposure in 125 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
"to evaluate the influence of two maternal high-fat diets with different caloric contents on anxiety-like behavior in young-adult offspring and their sensitivity to acute fluoxetine."8.02High-caloric or isocaloric maternal high-fat diets differently affect young-adult offspring behavior in anxiety-related tests and offspring sensitivity to acute fluoxetine. ( Benjamim, RAC; Cadena-Burbano, EV; Cavalcanti, CCL; Costa, TL; Da Silva Aragão, R; Lago, AB; Manhães-De-Castro, R; Oliveira, TRDP; Silva, EHM; Silva, JM, 2021)
"The aim of this study was to determine the effects of maternal fluoxetine treatment on anxiety-like and depressive-like behaviours in adolescent offspring as well as associated glutamatergic markers, using a clinically relevant rodent model of depression."7.91Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model o ( Fernandez, F; Lum, JS; Millard, SJ; Newell, KA; Weston-Green, K, 2019)
" We have previously shown in rats that fetal and neonatal exposure to the SSRI antidepressant fluoxetine results in metabolic perturbations including increased hepatic triglyceride content; a hallmark of non-alcoholic fatty liver disease (NAFLD)."7.85Increased incidence of non-alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis. ( De Long, NE; Hardy, DB; Holloway, AC; Ma, N, 2017)
" At 12 months, but not earlier, DEX-exposed mice displayed depression-like behavior and impaired hippocampal neurogenesis, not reversible by the antidepressant fluoxetine (FLX)."7.81Alterations in circadian entrainment precede the onset of depression-like behavior that does not respond to fluoxetine. ( Bose, R; Ceccatelli, S; Conti, M; DuPont, C; Onishchenko, N; Raciti, M; Spulber, S, 2015)
"Several epidemiological studies have reported an association between arsenic exposure and increased rates of psychiatric disorders, including depression, in exposed populations."7.80Fluoxetine treatment ameliorates depression induced by perinatal arsenic exposure via a neurogenic mechanism. ( Allan, AM; Solomon, BR; Tyler, CR; Ulibarri, AL, 2014)
"In contrast to the adult, fluoxetine exposure in utero induces pulmonary hypertension in the fetal rat as a result of a developmentally regulated increase in pulmonary vascular smooth muscle proliferation."7.74Prenatal exposure to fluoxetine induces fetal pulmonary hypertension in the rat. ( Belik, J; Fornaro, E; Li, D; Pan, J, 2007)
"Fluoxetine (FLX) has been widely prescribed for depression during pregnancy and/or lactation."7.74Behavioral evaluation of male and female mice pups exposed to fluoxetine during pregnancy and lactation. ( Costa, LC; Lisboa, SF; Moreira, EG; Oliveira, PE; Venâncio, EJ, 2007)
"The aim of the present study was to compare the toxic effects of fluoxetine (F) (8 and 16 mg/kg) and venlafaxine (V) (40 and 80 mg/kg) administered during the third week of pregnancy on early development of rats."7.70Postnatal development of rats exposed to fluoxetine or venlafaxine during the third week of pregnancy. ( Altenburg, SP; da-Silva, VA; Lindsey, CJ; Malheiros, LR; Thomaz, TG, 1999)
"We present the results of a comparative analysis of the effects of the chronic administration of the selective serotonin reuptake inhibitors fluoxetine (5."5.37[Influence of fluoxetine and paroxetine on anxiety-like behavior in young and adult prenatally stressed male rats]. ( Akulova, VK; Fedotova, YO; Ordian, NÉ; Pivina, SG, 2011)
"Fluoxetine-treated dams gave birth to litters 15% smaller than usual and to pups of reduced weight (until postnatal day 7)."5.37Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring. ( Afrasiab-Middelman, A; Dederen, JP; Homberg, JR; Jonkers, M; Kiliaan, AJ; Korte-Bouws, GA; Martens, GJ; Olivier, JD; Peeters, EJ; Roelofs, JJ; Schubert, D; Vallès, A; van Heesch, F, 2011)
"Initial experiments measured the half-life of fluoxetine and dosing required to achieve human therapeutic blood levels in the guinea pig."5.33Long-term effects of fluoxetine or vehicle administration during pregnancy on behavioral outcomes in guinea pig offspring. ( Baker, GB; Boksa, P; Malik, S; Vartazarmian, R, 2005)
" By chronically exposing pregnant/lactating mice to MeHg, we found persistent behavioural changes in the male offspring, which exhibited depression-like behaviour that could be reversed by chronic treatment with the antidepressant fluoxetine."4.89Long-lasting neurotoxic effects of exposure to methylmercury during development. ( Bose, R; Ceccatelli, S; Edoff, K; Onishchenko, N; Spulber, S, 2013)
"During and following pregnancy, women are at high risk of experiencing depression, for which fluoxetine (FLX; brand names Prozac, Sarafem, Rapiflux) is the most commonly prescribed treatment."4.89Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature. ( Dyck, RH; Kiryanova, V; McAllister, BB, 2013)
"There is no conclusive evidence for increased risk for malformations but paroxetine and possibly fluoxetine use in early pregnancy may be associated with a small increased risk for cardiovascular malformations."4.86Risks associated with in utero and lactation exposure to selective serotonin reuptake inhibitors (SSRIs). ( Ellfolk, M; Malm, H, 2010)
" In particular, we treated female and male rats with fluoxetine (FLX 15 mg/kg dissolved in drinking water) during prenatal or early postnatal life, and we evaluated different pathological-like phenotypes (cognitive deficit, anhedonia, and anxiety) by exposing the rats to a battery of behavioral tests during adolescence and adulthood."4.31Perinatal serotonergic manipulation shapes anhedonic and cognitive behaviors in a sex- and age-dependent manner: Identification of related biological functions at central and peripheral level. ( Brivio, P; Calabrese, F; Dolci, B; Fumagalli, F; Gallo, MT, 2023)
"During pregnancy, women are prone to depression, for which selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, are usually the first-line treatment."4.12Prenatal exposure to fluoxetine modulates emotionality and aversive memory in male and female rat offspring. ( Brandão, LEM; Câmara, DA; Cavalcante, JS; de Aquino, ACQ; Engelberth, RCJG; Fiuza, FP; Lima, RH; Linhares, SSG; Meurer, YDSR, 2022)
" The selective serotonin reuptake inhibitor fluoxetine (FLX) is the first-line antidepressant drug prescribed during pregnancy."4.12Prenatal fluoxetine has long-lasting, differential effects on respiratory control in male and female rats. ( Biancardi, V; Bícego, KC; Funk, GD; Gargaglioni, LH; Marques, DA; Patrone, LGA; Vicente, MC, 2022)
"Selective serotonin reuptake inhibitors (SSRI), such as fluoxetine, are used as first-line antidepressant medication during pregnancy."4.02Perinatal SSRI exposure affects brain functional activity associated with whisker stimulation in adolescent and adult rats. ( Hoehn, M; Homberg, JR; Schubert, D; Van der Knaap, N; Wiedermann, D, 2021)
"to evaluate the influence of two maternal high-fat diets with different caloric contents on anxiety-like behavior in young-adult offspring and their sensitivity to acute fluoxetine."4.02High-caloric or isocaloric maternal high-fat diets differently affect young-adult offspring behavior in anxiety-related tests and offspring sensitivity to acute fluoxetine. ( Benjamim, RAC; Cadena-Burbano, EV; Cavalcanti, CCL; Costa, TL; Da Silva Aragão, R; Lago, AB; Manhães-De-Castro, R; Oliveira, TRDP; Silva, EHM; Silva, JM, 2021)
" Furthermore, stressed dams were treated with different doses of fluoxetine (FLX; 5, 10and 25 mg/kg) during pregnancy and the postpartum period."4.02Perinatal fluoxetine dose-dependently affects prenatal stress-induced neurobehavioural abnormalities, HPA-axis functioning and underlying brain alterations in rat dams and their offspring. ( Amani, M; Homberg, JR; Houwing, DJ; Salari, AA, 2021)
"Fluoxetine is often prescribed to treat depression during pregnancy."4.02Prenatal fluoxetine impairs non-hippocampal but not hippocampal memory in adult male rat offspring. ( Ampuero, E; de Vries, EF; Díaz-Galarce, R; Donoso-Ramos, JP; Doorduin, J; Linsambarth, S; Moraga-Amaro, R; Pacheco, R; Peña, F; Stehberg, J; Ugalde, V; Wyneken, U, 2021)
" In this regard, we chronically treated normal female mice with different dosages (0, 10, and 20 mg/kg) of fluoxetine (FLU) for 2 weeks before mating them with drug-free male mice and then tested the offspring for anxiety/depression-like behaviors with the elevated plus maze and the tail-suspension test after exposing to acute or chronic stress in adult period."3.91Chronic exposure to fluoxetine of female mice before mating causes impaired stress resilience in female offspring. ( Li, J; Si, J; Suo, L; Yang, C; Zhang, Y, 2019)
"The aim of this study was to determine the effects of maternal fluoxetine treatment on anxiety-like and depressive-like behaviours in adolescent offspring as well as associated glutamatergic markers, using a clinically relevant rodent model of depression."3.91Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model o ( Fernandez, F; Lum, JS; Millard, SJ; Newell, KA; Weston-Green, K, 2019)
"We studied the effect of chronic injections of serotonin reuptake inhibitor fluoxetine to rats during pregnancy on physiological and behavioral characteristics of female offspring during the prepubertal period."3.88Effect of Fluoxetine in Prenatal Period on Nociceptive System Reactivity and Psychoemotional Behavior in Young Female Rats. ( Butkevich, IP; Mikhailenko, VA, 2018)
"Fluoxetine (FLX) is an antidepressant from the selective serotonin reuptake inhibitor class that has largely been used for the treatment of depression in pregnancy."3.88Maternal exposure to fluoxetine during gestation and lactation induces long lasting changes in the DNA methylation profile of offspring's brain and affects the social interaction of rat. ( Estrada, VB; Francis-Oliveira, J; Gomes, MV; Moreira, EG; Pelosi, GG; Silva, AS; Toffoli, LV; Veríssimo, LF, 2018)
"Our goal was to find out the impact of two antidepressant drugs with various mechanisms of action - imipramine and fluoxetine, on the frontal cortex mitochondria-enriched fraction in an animal model of depression based on the prenatal stress procedure."3.88Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment. ( Basta-Kaim, A; Chamera, K; Głombik, K; Kotarska, K; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E, 2018)
"The study aimed to evaluate if maternal exposure to fluoxetine (FLX) during pregnancy and lactation would result in altered aortic reactivity in adult offspring."3.88Intrauterine and lactational exposure to fluoxetine enhances endothelial modulation of aortic contractile response in adult female rats. ( Akamine, EH; Carvalho, MHC; Ceravolo, GS; Echem, C; Gerardin, DCC; Higashi, CM; Lucchetti, BFC; Moreira, EG; Pelosi, GG; Pinge-Filho, P; Sartoretto, SM, 2018)
" We have previously shown in rats that fetal and neonatal exposure to the SSRI antidepressant fluoxetine results in metabolic perturbations including increased hepatic triglyceride content; a hallmark of non-alcoholic fatty liver disease (NAFLD)."3.85Increased incidence of non-alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis. ( De Long, NE; Hardy, DB; Holloway, AC; Ma, N, 2017)
" To this end, pregnant female dams were exposed to saline or fluoxetine (FLX) throughout pregnancy, and the behavior of the offspring was examined."3.83Prenatal exposure to selective serotonin reuptake inhibitors (SSRI) increases aggression and modulates maternal behavior in offspring mice. ( Avitsur, R; Levy, S; Svirsky, N, 2016)
"Fluoxetine (FLX) is an antidepressant worldwide prescribed throughout life stages, including pregnancy and breastfeeding."3.83Does fish oil or folic acid prevent vascular changes in female progeny caused by maternal exposure to fluoxetine? ( Barbosa, DS; Ceravolo, GS; Gameiro, JG; Higachi, L; Higashi, CM; Matsumoto, AK; Moreira, EG; Moura, KF; Oliveira, LC, 2016)
" At 12 months, but not earlier, DEX-exposed mice displayed depression-like behavior and impaired hippocampal neurogenesis, not reversible by the antidepressant fluoxetine (FLX)."3.81Alterations in circadian entrainment precede the onset of depression-like behavior that does not respond to fluoxetine. ( Bose, R; Ceccatelli, S; Conti, M; DuPont, C; Onishchenko, N; Raciti, M; Spulber, S, 2015)
"Several epidemiological studies have reported an association between arsenic exposure and increased rates of psychiatric disorders, including depression, in exposed populations."3.80Fluoxetine treatment ameliorates depression induced by perinatal arsenic exposure via a neurogenic mechanism. ( Allan, AM; Solomon, BR; Tyler, CR; Ulibarri, AL, 2014)
"Fluoxetine is an antidepressant that has been largely used for treatment of depression in pregnancy."3.80Maternal exposure to fluoxetine during gestation and lactation affects the DNA methylation programming of rat's offspring: modulation by folic acid supplementation. ( Gomes, MV; Moreira, EG; Oliveira, JF; Pelosi, GG; Rodrigues, GM; Silva, AS; Toffoli, LV, 2014)
" Her mother had been taking fluoxetine (20 mg daily) during the second and third trimesters of her pregnancy."3.74Prolonged neonatal complications after in utero exposure to fluoxetine. ( Alehan, F; Gürakan, B; Saygi, S; Tarcan, A, 2008)
"Three groups of female rats received either distilled water or doses of fluoxetine 8 and 12 mg/kg orally from the 6th to the 20th day of pregnancy."3.74Developmental and behavioral consequences of prenatal fluoxetine. ( Ashok, KP; Bairy, I; Bairy, KL; Madhyastha, S; Malini, S, 2007)
"Fluoxetine (FLX) has been widely prescribed for depression during pregnancy and/or lactation."3.74Behavioral evaluation of male and female mice pups exposed to fluoxetine during pregnancy and lactation. ( Costa, LC; Lisboa, SF; Moreira, EG; Oliveira, PE; Venâncio, EJ, 2007)
"In contrast to the adult, fluoxetine exposure in utero induces pulmonary hypertension in the fetal rat as a result of a developmentally regulated increase in pulmonary vascular smooth muscle proliferation."3.74Prenatal exposure to fluoxetine induces fetal pulmonary hypertension in the rat. ( Belik, J; Fornaro, E; Li, D; Pan, J, 2007)
" Fluoxetine (FLX), a selective serotonin reuptake inhibitor (SSRI) antidepressant, has been widely prescribed for depression during pregnancy and/or lactation."3.74Maternal exposure to the antidepressant fluoxetine impairs sexual motivation in adult male mice. ( de Faria, MJ; Gerardin, DC; Gouvêa, TS; Moreira, EG; Morimoto, HK, 2008)
" In this study, we report that the depression-like behavior in MeHg-exposed male mice is reversed by chronic treatment with the antidepressant fluoxetine."3.74Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury. ( Castrén, E; Ceccatelli, S; Karpova, N; Onishchenko, N; Sabri, F, 2008)
" Her mother was on 20 mg of fluoxetine throughout her pregnancy."3.73Fluoxetine withdrawal syndrome in the newborn. ( Anbu, AT; Theodore, A, 2006)
" However, maternal use of high doses of fluoxetine throughout pregnancy may be associated with a risk for low birth weight."3.72Birth outcomes after prenatal exposure to antidepressant medication. ( Altshuler, L; Haynes, D; Hendrick, V; Hwang, S; Smith, LM; Suri, R, 2003)
"The aim of the present study was to compare the toxic effects of fluoxetine (F) (8 and 16 mg/kg) and venlafaxine (V) (40 and 80 mg/kg) administered during the third week of pregnancy on early development of rats."3.70Postnatal development of rats exposed to fluoxetine or venlafaxine during the third week of pregnancy. ( Altenburg, SP; da-Silva, VA; Lindsey, CJ; Malheiros, LR; Thomaz, TG, 1999)
"Prospectively identified fluoxetine-exposed pregnancies were evaluated to determine whether fluoxetine, a serotonin reuptake inhibitor commonly used for the treatment of depression and obsessive-compulsive disorder, might be associated with neonatal complications after maternal fluoxetine exposure during the third trimester through delivery."3.69Effects of third trimester fluoxetine exposure on the newborn. ( Goldstein, DJ, 1995)
" We found that these effects were differential between female mice dosed lactationally or peripartally, and there were also impacts on maternal mammary gland at weaning in both of these groups."1.91In utero, lactational, or peripartal fluoxetine administration has differential implications on the murine maternal skeleton. ( Brettingen, LJ; Charles, JF; Fricke, HP; Hernandez, LL; Krajco, CJ; Perry, MJ; Reisner, MA; Wake, LA, 2023)
" The aim of the study was to establish whether combined single and chronic administration of aripiprazole (ARI) and fluoxetine (FLU) affects animal locomotor activity or modifies spatial memory functions in female rats exposed to ethyl alcohol."1.46Effect of combined administration of aripiprazole and fluoxetine on cognitive functions in female rats exposed to ethyl alcohol. ( Czaja, N; Kus, K; Nowakowska, E; Ratajczak, P; Zaprutko, T, 2017)
"Women with major depressive disorder during pregnancy often use selective serotonin reuptake inhibitors (SSRIs) antidepressants."1.46Prenatal fluoxetine modifies the behavioral and hormonal responses to stress in male mice: role for glucocorticoid insensitivity. ( Avitsur, R, 2017)
" On the other hand, little is known about the impact of chronic administration of various antidepressant drugs on the brain mitochondria, as a target for the pharmacotherapy of depression."1.46Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Chamera, K; Głombik, K; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E, 2017)
"Stress during pregnancy is associated with lifetime negative consequences for the offspring."1.46Increased symptoms of illness following prenatal stress: Can it be prevented by fluoxetine? ( Avitsur, R, 2017)
"Fluoxetine (FLX) has been widely prescribed for use during depression in pregnancy and lactation."1.43In utero and lactational exposure to fluoxetine delays puberty onset in female rats offspring. ( Anselmo-Franci, JA; Ceravolo, GS; de Azevedo Camin, N; Dos Santos, AH; Gerardin, DC; Kiss, AC; Mesquita, Sde F; Moreira, EG; Pelosi, GG; Vieira, ML, 2016)
"The long-term use of fluoxetine via oral route by pregnant and lactating rats modifies the mandibular bone mass."1.42Effects of treatment with fluoxetine on mandibular development: A morphological study in rats. ( Baratella-Evêncio, L; Correia-Leite de Marcelos, PG; Cruz Perez, DE; de Moraes Ramos-Perez, FM; Evêncio Neto, J; Regueira, LS; Santiago-Jaegger, IM, 2015)
"Major depression is one of the most prevalent mental disorders in the population."1.40Prenatal lipopolysaccharide exposure increases depression-like behaviors and reduces hippocampal neurogenesis in adult rats. ( Lin, YL; Wang, S, 2014)
"Fluoxetine-treated dams gave birth to litters 15% smaller than usual and to pups of reduced weight (until postnatal day 7)."1.37Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring. ( Afrasiab-Middelman, A; Dederen, JP; Homberg, JR; Jonkers, M; Kiliaan, AJ; Korte-Bouws, GA; Martens, GJ; Olivier, JD; Peeters, EJ; Roelofs, JJ; Schubert, D; Vallès, A; van Heesch, F, 2011)
"We present the results of a comparative analysis of the effects of the chronic administration of the selective serotonin reuptake inhibitors fluoxetine (5."1.37[Influence of fluoxetine and paroxetine on anxiety-like behavior in young and adult prenatally stressed male rats]. ( Akulova, VK; Fedotova, YO; Ordian, NÉ; Pivina, SG, 2011)
" Dam dosing was adjusted to reflect the 50th and 85th percentiles of serum concentrations observed in pregnant women."1.37Serotonin transporter occupancy in rats exposed to serotonin reuptake inhibitors in utero or via breast milk. ( Bourke, CH; Capello, CF; Nemeroff, A; Newport, DJ; Owens, MJ; Ritchie, JC; Stowe, ZN, 2011)
"Fluoxetine is an antidepressant drug, only recently discovered to be a QT interval prolonging agent."1.33Prolonged QT interval in an infant of a fluoxetine treated mother. ( Dubnov, G; Fogelman, R; Merlob, P, 2005)
"Initial experiments measured the half-life of fluoxetine and dosing required to achieve human therapeutic blood levels in the guinea pig."1.33Long-term effects of fluoxetine or vehicle administration during pregnancy on behavioral outcomes in guinea pig offspring. ( Baker, GB; Boksa, P; Malik, S; Vartazarmian, R, 2005)
"Fluoxetine is a widely used serotonin reuptake inhibitor effective in the treatment of depression."1.29A developmental neurotoxicity evaluation of the effects of prenatal exposure to fluoxetine in rats. ( Acuff-Smith, KD; Buelke-Sam, J; Fisher, JE; Moran, MS; Schilling, MA; Vorhees, CV, 1994)

Research

Studies (125)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (7.20)18.2507
2000's20 (16.00)29.6817
2010's66 (52.80)24.3611
2020's30 (24.00)2.80

Authors

AuthorsStudies
Sylte, OC1
Johansen, JS1
Heinla, I3
Houwing, DJ6
Olivier, JDA5
Heijkoop, R3
Snoeren, EMS3
Marks, C1
Silvola, R1
Teal, E1
Quinney, SK1
Haas, DM1
Leussis, MP1
Thanos, JM1
Powers, A1
Peterson, E1
Head, JP1
McGovern, NJ1
Malarkey, FJ1
Drake, A1
Ramsteijn, AS2
Verkaik-Schakel, RN1
Plösch, T1
Linhares, SSG2
Meurer, YDSR2
Aquino, A1
Câmara, DA2
Brandão, LEM2
Dierschnabel, AL1
Fiuza, FP2
Lima, RH2
Engelberth, RC1
Cavalcante, JS2
Biancardi, V1
Patrone, LGA1
Vicente, MC1
Marques, DA1
Bícego, KC1
Funk, GD1
Gargaglioni, LH1
Ascencio Gutierrez, V1
Carrillo, AA1
Boersma, GJ1
Tamashiro, KLK1
Moran, TH1
Iñiguez, SD1
Treesukosol, Y1
Arzuaga, AL1
Edmison, DD1
Mroczek, J1
Larson, J1
Ragozzino, ME1
de Aquino, ACQ1
Engelberth, RCJG1
Zaidan, H2
Wnuk, A1
Aderka, IM1
Kajta, M1
Gaisler-Salomon, I2
Pawluski, JL11
Murail, P1
Grudet, F1
Bys, L1
Golubeva, AV1
Bastiaanssen, T1
Oberlander, TF1
Cryan, JF1
O'Mahony, SM1
Charlier, TD6
Lan, Z1
Tachibana, RO1
Kanno, K1
Gallo, MT1
Brivio, P1
Dolci, B1
Fumagalli, F1
Calabrese, F1
Prowse, KL1
Law, H1
Raez-Villanueva, S1
Markovic, F1
Wang, M1
Borojevic, R1
Parsons, SP1
Vincent, AD1
Holloway, AC4
Ratcliffe, EM1
Fricke, HP2
Krajco, CJ2
Perry, MJ2
Reisner, MA1
Brettingen, LJ1
Wake, LA2
Charles, JF2
Hernandez, LL2
Desorcy-Scherer, KM1
Yang, C1
Si, J1
Suo, L1
Zhang, Y1
Li, J1
Schuttel, K1
Struik, EL1
Arling, C1
Christodoulos, IN1
Chyou, TY1
Nishtala, PS1
Visco, DB1
Manhães-de-Castro, R2
da Silva, MM1
Dantas-Alves, JS1
Costa-de-Santana, BJR1
Braz, GRF1
da Silva, AI1
Lagranha, CJ1
Toscano, AE1
Si, Y1
Xue, X1
Liu, S1
Feng, C1
Zhang, H1
Zhang, S1
Ren, Y1
Ma, H1
Dong, Y1
Li, H1
Xie, L1
Zhu, Z1
Van der Knaap, N1
Wiedermann, D1
Schubert, D2
Hoehn, M1
Homberg, JR6
Cavalcanti, CCL1
Da Silva Aragão, R1
Cadena-Burbano, EV1
Oliveira, TRDP1
Silva, JM1
Benjamim, RAC1
Lago, AB1
Silva, EHM1
Costa, TL1
Galiani, D1
Vuong, HE1
Coley, EJL1
Kazantsev, M1
Cooke, ME1
Rendon, TK1
Paramo, J1
Hsiao, EY1
Scarborough, J1
Mueller, FS1
Weber-Stadlbauer, U1
Mattei, D1
Opitz, L1
Cattaneo, A1
Richetto, J1
Qiu, W1
Go, KA1
Wen, Y1
Duarte-Guterman, P1
Eid, RS1
Galea, LAM1
Amani, M1
Salari, AA2
Moraga-Amaro, R1
Díaz-Galarce, R1
Donoso-Ramos, JP1
Ugalde, V1
Linsambarth, S1
Doorduin, J1
de Vries, EF1
Ampuero, E1
Peña, F1
Pacheco, R1
Wyneken, U1
Stehberg, J1
Kus, K2
Ratajczak, P1
Czaja, N1
Zaprutko, T2
Nowakowska, E2
Avitsur, R5
Kiryanova, V7
Meunier, SJ2
Dyck, RH7
Głombik, K3
Stachowicz, A2
Trojan, E3
Olszanecki, R2
Ślusarczyk, J3
Suski, M2
Chamera, K3
Budziszewska, B2
Lasoń, W2
Basta-Kaim, A3
De Long, NE2
Hardy, DB2
Ma, N1
Gemmel, M6
Hazlett, M1
Bögi, E3
De Lacalle, S3
Hill, LA3
Kokras, N4
Hammond, GL2
Dalla, C4
Nagano, R1
Nagano, M2
Nakai, A1
Takeshita, T1
Suzuki, H2
Marques, BVD1
Higashi, CM3
da S Novi, DRB1
Zanluqui, NG1
Gregório, TF1
Pinge-Filho, P2
Gerardin, DCC3
Pelosi, GG7
Moreira, EG11
Ceravolo, GS5
Harmeyer, D1
Fillet, M1
Kotarska, K1
Belovicová, K1
Ujhazy, E1
Mach, M1
Koprdova, R1
Zilava, L1
Garafová, A1
Jezova, D1
Dubovicky, M1
Sartoretto, SM1
Echem, C1
Lucchetti, BFC1
Carvalho, MHC1
Akamine, EH1
Hernández, A1
Fernández-Guasti, A1
Butkevich, IP2
Mikhailenko, VA2
Silva, AS2
Toffoli, LV2
Estrada, VB1
Veríssimo, LF3
Francis-Oliveira, J2
Gomes, MV3
Mort, SC1
Millard, SJ1
Lum, JS1
Fernandez, F1
Weston-Green, K1
Newell, KA1
Nguyen, TA1
Chow, T1
Riggs, W1
Rurak, D1
Barbosa, MA1
Yu, W1
Yen, YC1
Lee, YH1
Tan, S1
Xiao, Y1
Lokman, H1
Ting, AKT1
Ganegala, H1
Kwon, T1
Ho, WK1
Je, HS1
Ratajczak, PK1
Szczepański, M1
Bond, CM1
Johnson, JC1
Chaudhary, V1
McCarthy, EM1
McWhorter, ML1
Woehrle, NS1
Ceccatelli, S3
Bose, R2
Edoff, K1
Onishchenko, N3
Spulber, S2
Ponte, B1
Barbosa, AP1
Britto, LR1
Rayen, I4
Steinbusch, HW5
Lin, YL2
Wang, S2
McAllister, BB2
Rodrigues, GM1
Oliveira, JF1
Tyler, CR1
Solomon, BR1
Ulibarri, AL1
Allan, AM1
Barry, EJ1
Pinelli, C1
Wood, GA1
Morrison, KM1
Taylor, VH1
Gerstein, HC1
Moore, CJ1
DeLong, NE1
Chan, KA1
Petrik, JJ1
Sloboda, DM1
Umemori, J1
Winkel, F1
Castrén, E2
Karpova, NN1
Levy, S2
Grinshpahet, R2
Goren, N2
Hirsh, O1
Zalko, A1
Correia-Leite de Marcelos, PG1
Regueira, LS1
Santiago-Jaegger, IM1
Cruz Perez, DE1
de Moraes Ramos-Perez, FM1
Evêncio Neto, J1
Baratella-Evêncio, L1
Conti, M1
DuPont, C1
Raciti, M1
Svirsky, N1
Frazer, S1
Otomo, K1
Dayer, A1
Lotus, T1
van Donkelaar, E2
Boulle, F2
Machiels, B2
Kroeze, Y2
Kumar, N2
Kenis, G2
Van den Hove, DL1
Steinbusch, HWM1
van den Hove, DLA1
Vecchiarelli, HA1
Hill, MN1
Matsumoto, AK1
Gameiro, JG1
Moura, KF1
Higachi, L1
Oliveira, LC1
Barbosa, DS1
Loftus, T1
Dos Santos, AH1
Vieira, ML2
de Azevedo Camin, N1
Anselmo-Franci, JA1
Kiss, AC1
Mesquita, Sde F2
Gerardin, DC3
Fatehi-Gharehlar, L1
Motayagheni, N1
Weinstein, I1
Kirshenboim, O1
Chlebowski, N1
Smith, VM2
Antle, MC2
Alehan, F1
Saygi, S1
Tarcan, A1
Gürakan, B1
Ellfolk, M1
Malm, H1
Olivier, JD1
Vallès, A1
van Heesch, F1
Afrasiab-Middelman, A1
Roelofs, JJ1
Jonkers, M1
Peeters, EJ1
Korte-Bouws, GA1
Dederen, JP1
Kiliaan, AJ1
Martens, GJ1
Pivina, SG1
Fedotova, YO1
Akulova, VK1
Ordian, NÉ1
Capello, CF1
Bourke, CH1
Ritchie, JC1
Stowe, ZN1
Newport, DJ1
Nemeroff, A1
Owens, MJ1
Sit, D1
Perel, JM1
Wisniewski, SR1
Helsel, JC1
Luther, JF1
Wisner, KL1
Smit-Rigter, LA1
Noorlander, CW1
von Oerthel, L1
Chameau, P1
Smidt, MP1
van Hooft, JA1
Lin, SY1
Richtand, NM1
Ahlbrand, R1
Horn, P1
Tambyraja, R1
Grainger, M1
Bronson, SL1
McNamara, RK1
Liu, M1
Inagaki, H1
Kawada, T1
Hamada, RY1
Gonzaga, NI1
Bacchi, AD1
Barbieri, M1
Nulman, I1
Rovet, J1
Stewart, DE1
Wolpin, J1
Pace-Asciak, P1
Shuhaiber, S1
Koren, G1
Bolaños, CA1
Trksak, GH1
Cohen, OS1
Jackson, D1
Hendrick, V1
Smith, LM1
Suri, R1
Hwang, S1
Haynes, D1
Altshuler, L1
Condon, J1
Vartazarmian, R1
Malik, S1
Baker, GB1
Boksa, P1
Dubnov, G1
Fogelman, R1
Merlob, P1
Morrison, JL1
Riggs, KW1
Rurak, DW1
Lavenstein, B1
Anbu, AT1
Theodore, A1
Bairy, KL1
Madhyastha, S1
Ashok, KP1
Bairy, I1
Malini, S1
Lisboa, SF1
Oliveira, PE1
Costa, LC1
Venâncio, EJ1
Fornaro, E1
Li, D1
Pan, J1
Belik, J1
Forcelli, PA1
Heinrichs, SC1
Ferris, MJ1
Mactutus, CF1
Silvers, JM1
Hasselrot, U1
Beaudin, SA1
Strupp, BJ1
Booze, RM1
Kwon, P1
Lefkowitz, W1
McAdam, TD1
Brien, JF1
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Gouvêa, TS1
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de Faria, MJ1
Karpova, N1
Sabri, F1
Goldberg, HL1
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Schilling, MA1
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Cabrera, TM1
Battaglia, G1
Spencer, MJ1
Goldstein, DJ1
Vathy, I1
Sokol, J1
Etgen, AM1
McReynolds, AM1
Meyer, JS1
da-Silva, VA1
Altenburg, SP1
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Thomaz, TG1
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Yan, QS1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Perinatal Stress and Gene Influences: Pathways to Infant Vulnerability[NCT00525226]1,431 participants (Actual)Observational2007-09-30Completed
Antidepressant Use During Pregnancy[NCT00279370]283 participants (Actual)Observational1999-09-30Completed
Transcranial Direct Current Stimulation (tDCS) for Depression in Pregnancy: A Pilot Study[NCT02116127]20 participants (Actual)Interventional2014-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for fluoxetine and Delayed Effects, Prenatal Exposure

ArticleYear
Long-lasting neurotoxic effects of exposure to methylmercury during development.
    Journal of internal medicine, 2013, Volume: 273, Issue:5

    Topics: Animals; Antidepressive Agents, Second-Generation; Cell Proliferation; Cellular Senescence; Depressi

2013
Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature.
    Developmental neuroscience, 2013, Volume: 35, Issue:6

    Topics: Animals; Anxiety; Brain; Depression; Female; Fluoxetine; Humans; Pregnancy; Prenatal Exposure Delaye

2013
Risks associated with in utero and lactation exposure to selective serotonin reuptake inhibitors (SSRIs).
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 30, Issue:2

    Topics: Adult; Breast Feeding; Cardiovascular Abnormalities; Congenital Abnormalities; Female; Fluoxetine; H

2010
Fluoxetine during pregnancy: impact on fetal development.
    Reproduction, fertility, and development, 2005, Volume: 17, Issue:6

    Topics: Animals; Antidepressive Agents, Second-Generation; Circadian Rhythm; Depression; Disease Models, Ani

2005
Psychotropic drugs in pregnancy and lactation.
    International journal of psychiatry in medicine, 1994, Volume: 24, Issue:2

    Topics: Clozapine; Embryonic and Fetal Development; Female; Fluoxetine; Humans; Lactation; Lithium; Mental D

1994

Other Studies

120 other studies available for fluoxetine and Delayed Effects, Prenatal Exposure

ArticleYear
Effects of perinatal fluoxetine exposure on novelty-induced social and non-social investigation behaviors in a seminatural environment.
    Psychopharmacology, 2021, Volume: 238, Issue:12

    Topics: Animals; Behavior, Animal; Female; Fluoxetine; Male; Pregnancy; Prenatal Exposure Delayed Effects; R

2021
Comparing newborn outcomes after prenatal exposure to individual antidepressants: A retrospective cohort study.
    Pharmacotherapy, 2021, Volume: 41, Issue:11

    Topics: Antidepressive Agents; Bupropion; Citalopram; Duloxetine Hydrochloride; Escitalopram; Female; Fluoxe

2021
Sex differences in long-term behavioral alterations, especially anxiety, following prenatal fluoxetine exposure in C57BL/6 mice.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 211

    Topics: Animals; Anxiety; Autism Spectrum Disorder; Behavior, Animal; Communication; Depression; Female; Flu

2021
Perinatal exposure to fluoxetine and maternal adversity affect myelin-related gene expression and epigenetic regulation in the corticolimbic circuit of juvenile rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2022, Volume: 47, Issue:9

    Topics: Animals; Epigenesis, Genetic; Female; Fluoxetine; Gene Expression; Hippocampus; Humans; Male; Myelin

2022
Effects of prenatal exposure to fluoxetine on circadian rhythmicity in the locomotor activity and neuropeptide Y and 5-HT expression in male and female adult Wistar rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2022, Volume: 82, Issue:5

    Topics: Animals; Antidepressive Agents; Circadian Rhythm; Female; Fluoxetine; Locomotion; Male; Neuropeptide

2022
Prenatal fluoxetine has long-lasting, differential effects on respiratory control in male and female rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2022, 08-01, Volume: 133, Issue:2

    Topics: Animals; Carbon Dioxide; Female; Fluoxetine; Humans; Hypercapnia; Hyperventilation; Male; Placenta;

2022
Effect of early-life stress or fluoxetine exposure on later-life conditioned taste aversion learning in Sprague-Dawley rats.
    Neuroscience letters, 2022, 09-14, Volume: 787

    Topics: Animals; Avoidance Learning; Body Weight; Female; Fluoxetine; Lithium Chloride; Male; Prenatal Expos

2022
Prenatal stress and fluoxetine exposure in mice differentially affect repetitive behaviors and synaptic plasticity in adult male and female offspring.
    Behavioural brain research, 2023, 01-05, Volume: 436

    Topics: Animals; Autism Spectrum Disorder; Female; Fluoxetine; Humans; Male; Mice; Mice, Inbred C57BL; Neuro

2023
Prenatal exposure to fluoxetine modulates emotionality and aversive memory in male and female rat offspring.
    Behavioural pharmacology, 2022, 12-01, Volume: 33, Issue:8

    Topics: Animals; Anxiety; Female; Fluoxetine; Humans; Male; Placenta; Pregnancy; Prenatal Exposure Delayed E

2022
Pre-reproductive stress in adolescent female rats alters maternal care and DNA methylation patterns across generations.
    Stress (Amsterdam, Netherlands), 2023, Volume: 26, Issue:1

    Topics: Animals; DNA Methylation; Epigenesis, Genetic; Female; Fluoxetine; Humans; Male; Prenatal Exposure D

2023
Gestational stress and perinatal SSRIs differentially impact the maternal and neonatal microbiome-gut-brain axis.
    Journal of neuroendocrinology, 2023, Volume: 35, Issue:7

    Topics: Animals; Antidepressive Agents; Brain-Gut Axis; Female; Fluoxetine; Humans; Pregnancy; Prenatal Expo

2023
Chronic exposure of female mice to selective serotonin reuptake inhibitors during lactation induces vocal behavior deficits in pre-weaned offspring.
    Pharmacology, biochemistry, and behavior, 2023, Volume: 230

    Topics: Animals; Female; Fluoxetine; Humans; Lactation; Maternal Exposure; Mice; Pregnancy; Prenatal Exposur

2023
Perinatal serotonergic manipulation shapes anhedonic and cognitive behaviors in a sex- and age-dependent manner: Identification of related biological functions at central and peripheral level.
    Brain, behavior, and immunity, 2023, Volume: 114

    Topics: Animals; Anxiety; Behavior, Animal; Biomarkers; Brain; Cognition; Female; Fluoxetine; Humans; Male;

2023
Effects of in utero exposure to fluoxetine on the gastrointestinal tract of rat offspring.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 12-01, Volume: 325, Issue:6

    Topics: Animals; Colitis; Female; Fluoxetine; Humans; Inflammation; Male; Pregnancy; Prenatal Exposure Delay

2023
In utero, lactational, or peripartal fluoxetine administration has differential implications on the murine maternal skeleton.
    Physiological reports, 2023, Volume: 11, Issue:19

    Topics: Animals; Bone and Bones; Bone Development; Female; Fluoxetine; Humans; Lactation; Mice; Pregnancy; P

2023
Developmental fluoxetine exposure affects adolescent and adult bone depending on the dose and period of exposure in mice.
    Physiological reports, 2023, Volume: 11, Issue:23

    Topics: Animals; Bone and Bones; Depressive Disorder, Major; Female; Fluoxetine; Humans; Mice; Prenatal Expo

2023
Chronic exposure to fluoxetine of female mice before mating causes impaired stress resilience in female offspring.
    Journal of neural transmission (Vienna, Austria : 1996), 2019, Volume: 126, Issue:9

    Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Depression; Disease Mo

2019
Perinatal fluoxetine treatment and dams' early life stress history alter affective behavior in rat offspring depending on serotonin transporter genotype and sex.
    Behavioural brain research, 2020, 08-17, Volume: 392

    Topics: Affect; Animals; Animals, Newborn; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Anim

2020
Third-party prosocial behavior in adult female rats is impaired after perinatal fluoxetine exposure.
    Physiology & behavior, 2020, 08-01, Volume: 222

    Topics: Adult; Altruism; Animals; Behavior, Animal; Female; Fluoxetine; Humans; Male; Pregnancy; Prenatal Ex

2020
Safety of fluoxetine use in children and adolescents: a disproportionality analysis of the Food and Drug Administration Adverse Event Reporting System (FAERS) database.
    European journal of clinical pharmacology, 2020, Volume: 76, Issue:12

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Antidepressive Agents, Second-Generation; Anxie

2020
Early life fluoxetine treatment causes long-term lean phenotype in skeletal muscle of rats exposed to maternal lard-based high-fat diet.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 131

    Topics: Animals; Animals, Newborn; Body Weight; Citrate (si)-Synthase; Diet, High-Fat; Dietary Fats; Eating;

2020
CRTC1 signaling involvement in depression-like behavior of prenatally stressed offspring rat.
    Behavioural brain research, 2021, 02-05, Volume: 399

    Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Female; Fluoxetine; Male;

2021
Perinatal SSRI exposure affects brain functional activity associated with whisker stimulation in adolescent and adult rats.
    Scientific reports, 2021, 01-18, Volume: 11, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Disease Models, Animal; Female; Fluoxetine; Hippocampus; Magn

2021
High-caloric or isocaloric maternal high-fat diets differently affect young-adult offspring behavior in anxiety-related tests and offspring sensitivity to acute fluoxetine.
    Behavioural brain research, 2021, 04-09, Volume: 403

    Topics: Animals; Anxiety; Behavior, Animal; Diet, High-Fat; Disease Models, Animal; Energy Intake; Female; F

2021
Pre-reproductive stress in adolescent female rats alters oocyte microRNA expression and offspring phenotypes: pharmacological interventions and putative mechanisms.
    Translational psychiatry, 2021, 02-05, Volume: 11, Issue:1

    Topics: Animals; Female; Fluoxetine; Gene Expression; MicroRNAs; Oocytes; Phenotype; Pregnancy; Prenatal Exp

2021
Interactions between maternal fluoxetine exposure, the maternal gut microbiome and fetal neurodevelopment in mice.
    Behavioural brain research, 2021, 07-23, Volume: 410

    Topics: Animals; Brain; Cell Adhesion Molecules; Disease Models, Animal; Embryo, Mammalian; Female; Fluoxeti

2021
A novel murine model to study the impact of maternal depression and antidepressant treatment on biobehavioral functions in the offspring.
    Molecular psychiatry, 2021, Volume: 26, Issue:11

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Female; Fluoxetine; Mice; Pregna

2021
Maternal fluoxetine reduces hippocampal inflammation and neurogenesis in adult offspring with sex-specific effects of periadolescent oxytocin.
    Brain, behavior, and immunity, 2021, Volume: 97

    Topics: Adult Children; Animals; Autism Spectrum Disorder; Doublecortin Protein; Female; Fluoxetine; Hippoca

2021
Perinatal fluoxetine dose-dependently affects prenatal stress-induced neurobehavioural abnormalities, HPA-axis functioning and underlying brain alterations in rat dams and their offspring.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 104

    Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Brain; Female; Fluoxetine; Hippocampus; L

2021
Prenatal fluoxetine impairs non-hippocampal but not hippocampal memory in adult male rat offspring.
    Neuropharmacology, 2021, 10-01, Volume: 197

    Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Depression; Female; Fluoxetine; Food Pre

2021
Effect of combined administration of aripiprazole and fluoxetine on cognitive functions in female rats exposed to ethyl alcohol.
    Acta neurobiologiae experimentalis, 2017, Volume: 77, Issue:1

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Avoidance Learning; Central Nervous System Depressants;

2017
Prenatal fluoxetine modifies the behavioral and hormonal responses to stress in male mice: role for glucocorticoid insensitivity.
    Behavioural pharmacology, 2017, Volume: 28, Issue:5

    Topics: Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Corticosterone; Depres

2017
Behavioural outcomes of adult female offspring following maternal stress and perinatal fluoxetine exposure.
    Behavioural brain research, 2017, 07-28, Volume: 331

    Topics: Aging; Animals; Antidepressive Agents; Behavior, Animal; Depressive Disorder; Female; Fluoxetine; Ma

2017
Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 08-01, Volume: 78

    Topics: 14-3-3 Proteins; Animals; Antidepressive Agents; Cathepsin D; COP9 Signalosome Complex; Depression;

2017
Increased incidence of non-alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis.
    Journal of applied toxicology : JAT, 2017, Volume: 37, Issue:12

    Topics: Animals; Animals, Newborn; Epigenesis, Genetic; Female; Fluoxetine; Incidence; Inflammasomes; Lipoge

2017
Perinatal fluoxetine effects on social play, the HPA system, and hippocampal plasticity in pre-adolescent male and female rats: Interactions with pre-gestational maternal stress.
    Psychoneuroendocrinology, 2017, Volume: 84

    Topics: Animals; Anxiety; Behavior, Animal; Depression; Female; Fluoxetine; Hippocampus; Hypothalamo-Hypophy

2017
Differential effects of neonatal SSRI treatments on hypoxia-induced behavioral changes in male and female offspring.
    Neuroscience, 2017, Sep-30, Volume: 360

    Topics: Animals; Animals, Newborn; Behavior, Animal; Citalopram; Disease Models, Animal; Female; Fluoxetine;

2017
Intrauterine and lactation exposure to fluoxetine blunted in the offspring the aortic adaptive response induced by acute restraint stress.
    European journal of pharmacology, 2017, Oct-15, Volume: 813

    Topics: Adaptation, Physiological; Animals; Aorta; Female; Fluoxetine; Lactation; Male; Nitric Oxide; Pregna

2017
Perinatal fluoxetine prevents the effect of pre-gestational maternal stress on 5-HT in the PFC, but maternal stress has enduring effects on mPFC synaptic structure in offspring.
    Neuropharmacology, 2018, Volume: 128

    Topics: Age Factors; Animals; Animals, Newborn; Disks Large Homolog 4 Protein; Drug Administration Schedule;

2018
Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam.
    Behavioural brain research, 2018, Feb-26, Volume: 339

    Topics: Animals; Behavior, Animal; Corticosterone; Female; Fluoxetine; Hippocampus; Maternal Behavior; Neuro

2018
Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:2

    Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder; Disease Models, Animal; Female; Flu

2018
Perinatal exposure to venlafaxine leads to lower anxiety and depression-like behavior in the adult rat offspring.
    Behavioural pharmacology, 2018, Volume: 29, Issue:5

    Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Animals, Newborn; Anxiety; Anxiety Disorders; Behavio

2018
Intrauterine and lactational exposure to fluoxetine enhances endothelial modulation of aortic contractile response in adult female rats.
    Vascular pharmacology, 2018, Volume: 108

    Topics: Animals; Antidepressive Agents, Second-Generation; Aorta, Thoracic; Cyclooxygenase 1; Dose-Response

2018
Male rats with same-sex preference show higher immobility in the forced swim test, but similar effects of fluoxetine and desipramine than males that prefer females.
    Pharmacology, biochemistry, and behavior, 2018, Volume: 171

    Topics: Animals; Desipramine; Female; Fluoxetine; Immobility Response, Tonic; Letrozole; Male; Motor Activit

2018
Effect of Fluoxetine in Prenatal Period on Nociceptive System Reactivity and Psychoemotional Behavior in Young Female Rats.
    Bulletin of experimental biology and medicine, 2018, Volume: 165, Issue:2

    Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Body Weight; Cognition; Female; Fluoxetine; Ma

2018
Maternal exposure to fluoxetine during gestation and lactation induces long lasting changes in the DNA methylation profile of offspring's brain and affects the social interaction of rat.
    Brain research bulletin, 2018, Volume: 142

    Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; DNA Methylation; Epigenesis, Genetic; Female; Fl

2018
Perinatal fluoxetine has enduring sexually differentiated effects on neurobehavioral outcomes related to social behaviors.
    Neuropharmacology, 2019, Volume: 144

    Topics: Animals; Female; Fluoxetine; Hippocampus; Male; Neurogenesis; Neuronal Plasticity; Pregnancy; Pregna

2019
Prenatal Stimulation of 5-HT
    Bulletin of experimental biology and medicine, 2019, Volume: 166, Issue:3

    Topics: Adaptation, Psychological; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Buspirone; Depressi

2019
Perinatal exposure to fluoxetine increases anxiety- and depressive-like behaviours and alters glutamatergic markers in the prefrontal cortex and hippocampus of male adolescent rats: A comparison between Sprague-Dawley rats and the Wistar-Kyoto rat model o
    Journal of psychopharmacology (Oxford, England), 2019, Volume: 33, Issue:2

    Topics: Animals; Anxiety; Depression; Disease Models, Animal; Female; Fluoxetine; Hippocampus; Male; Prefron

2019
Postnatal outcomes in lambs exposed antenatally and acutely postnatally to fluoxetine.
    Pediatric research, 2019, Volume: 85, Issue:7

    Topics: Animals; Animals, Newborn; Female; Fluoxetine; Heart Rate; Maternal Exposure; Pregnancy; Prenatal Ex

2019
Maternal exposure to fluoxetine during gestation and lactation does not alter plasma concentrations of testosterone, oestrogen or corticosterone in peripubertal offspring.
    Reproduction, fertility, and development, 2019, Volume: 31, Issue:5

    Topics: Animals; Corticosterone; Estrogens; Female; Fluoxetine; Male; Maternal Exposure; Placenta; Pregnancy

2019
Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male mice.
    Molecular brain, 2019, 04-01, Volume: 12, Issue:1

    Topics: Action Potentials; Animals; Behavior, Animal; Female; Fluoxetine; Interneurons; Male; Memory, Short-

2019
Perinatal fluoxetine exposure changes social and stress-coping behavior in adult rats housed in a seminatural environment.
    Neuropharmacology, 2019, Volume: 151

    Topics: Adaptation, Psychological; Animals; Behavior, Animal; Environment; Female; Fluoxetine; Pregnancy; Pr

2019
Antidepressant and anxiolytic efficacy of single, chronic and concomitant use of vortioxetine, dapoxetine and fluoxetine in prenatally stressed rats.
    Acta neurobiologiae experimentalis, 2019, Volume: 79, Issue:1

    Topics: Animals; Antidepressive Agents; Benzylamines; Disease Models, Animal; Drug Administration Schedule;

2019
Perinatal fluoxetine exposure results in social deficits and reduced monoamine oxidase gene expression in mice.
    Brain research, 2020, 01-15, Volume: 1727

    Topics: Animals; Antidepressive Agents; Autism Spectrum Disorder; Behavior, Animal; Brain; Exploratory Behav

2020
Fluoxetine exposure during pregnancy and lactation: Effects on acute stress response and behavior in the novelty-suppressed feeding are age and gender-dependent in rats.
    Behavioural brain research, 2013, Sep-01, Volume: 252

    Topics: Aging; Amygdala; Animals; Female; Fluoxetine; Lactation; Male; Paraventricular Hypothalamic Nucleus;

2013
Developmental fluoxetine exposure facilitates sexual behavior in female offspring.
    Psychopharmacology, 2014, Volume: 231, Issue:1

    Topics: Anal Canal; Analysis of Variance; Animals; Animals, Newborn; Brain; Estradiol; Estrous Cycle; Female

2014
Prenatal lipopolysaccharide exposure increases depression-like behaviors and reduces hippocampal neurogenesis in adult rats.
    Behavioural brain research, 2014, Feb-01, Volume: 259

    Topics: Age Factors; Animals; Antidepressive Agents, Second-Generation; Cell Proliferation; Depression; Fema

2014
Maternal exposure to fluoxetine during gestation and lactation affects the DNA methylation programming of rat's offspring: modulation by folic acid supplementation.
    Behavioural brain research, 2014, May-15, Volume: 265

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Brain; DNA Methylation; Exp

2014
Fluoxetine treatment ameliorates depression induced by perinatal arsenic exposure via a neurogenic mechanism.
    Neurotoxicology, 2014, Volume: 44

    Topics: Animals; Antidepressive Agents, Second-Generation; Arsenic; Depression; Female; Fluoxetine; Helpless

2014
Increased aggression, improved spatial memory, and reduced anxiety-like behaviour in adult male mice exposed to fluoxetine early in life.
    Developmental neuroscience, 2014, Volume: 36, Issue:5

    Topics: Aggression; Animals; Anxiety; Behavior, Animal; Conditioning, Classical; Fear; Female; Fluoxetine; M

2014
Antenatal exposure to the selective serotonin reuptake inhibitor fluoxetine leads to postnatal metabolic and endocrine changes associated with type 2 diabetes in Wistar rats.
    Toxicology and applied pharmacology, 2015, May-15, Volume: 285, Issue:1

    Topics: Adiposity; Animals; Blood Glucose; Chemical and Drug Induced Liver Injury; Chemokine CCL2; Diabetes

2015
Perinatal Administration of a Selective Serotonin Reuptake Inhibitor Induces Impairments in Reproductive Function and Follicular Dynamics in Female Rat Offspring.
    Reproductive sciences (Thousand Oaks, Calif.), 2015, Volume: 22, Issue:10

    Topics: Age Factors; Animals; Animals, Newborn; Apoptosis; CLOCK Proteins; Estrus; Female; Fluoxetine; Gene

2015
Distinct effects of perinatal exposure to fluoxetine or methylmercury on parvalbumin and perineuronal nets, the markers of critical periods in brain development.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2015, Volume: 44

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Cell Count; Extracellular Matrix Proteins; Female; Fl

2015
Prenatal fluoxetine exposure affects cytokine and behavioral response to an immune challenge.
    Journal of neuroimmunology, 2015, Jul-15, Volume: 284

    Topics: Age Factors; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Body Weight; C

2015
Effects of treatment with fluoxetine on mandibular development: A morphological study in rats.
    Acta histochemica, 2015, Volume: 117, Issue:6

    Topics: Animals; Animals, Newborn; Body Weight; Female; Fluoxetine; Male; Mandible; Pregnancy; Prenatal Expo

2015
Alterations in circadian entrainment precede the onset of depression-like behavior that does not respond to fluoxetine.
    Translational psychiatry, 2015, Jul-14, Volume: 5

    Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Circadian Rhythm; Corticosteron

2015
Prenatal exposure to selective serotonin reuptake inhibitors (SSRI) increases aggression and modulates maternal behavior in offspring mice.
    Developmental psychobiology, 2016, Volume: 58, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Female; Fluoxetine; Male; Maternal Behavior; Mice; Pregnancy;

2016
Early-life serotonin dysregulation affects the migration and positioning of cortical interneuron subtypes.
    Translational psychiatry, 2015, Sep-22, Volume: 5

    Topics: Animals; Cell Membrane; Cerebral Cortex; Disease Models, Animal; Female; Fluoxetine; Gene Expression

2015
Developmental fluoxetine and prenatal stress effects on serotonin, dopamine, and synaptophysin density in the PFC and hippocampus of offspring at weaning.
    Developmental psychobiology, 2016, Volume: 58, Issue:3

    Topics: Animals; Dopamine; Female; Fluoxetine; Hippocampus; Male; Prefrontal Cortex; Pregnancy; Prenatal Exp

2016
Prenatal stress and early-life exposure to fluoxetine have enduring effects on anxiety and hippocampal BDNF gene expression in adult male offspring.
    Developmental psychobiology, 2016, Volume: 58, Issue:4

    Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Femal

2016
Developmental fluoxetine exposure increases behavioral despair and alters epigenetic regulation of the hippocampal BDNF gene in adult female offspring.
    Hormones and behavior, 2016, Volume: 80

    Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Depression; Disease Models, Animal; Epigenesis,

2016
Effects of maternal stress and perinatal fluoxetine exposure on behavioral outcomes of adult male offspring.
    Neuroscience, 2016, Apr-21, Volume: 320

    Topics: Aggression; Animals; Behavior, Animal; Brain; Disease Models, Animal; Female; Fluoxetine; Male; Mate

2016
Does fish oil or folic acid prevent vascular changes in female progeny caused by maternal exposure to fluoxetine?
    Life sciences, 2016, May-01, Volume: 152

    Topics: Animals; Antidepressive Agents, Second-Generation; Blood Vessels; Female; Fish Oils; Fluoxetine; Fol

2016
Gestational stress and fluoxetine treatment differentially affect plasticity, methylation and serotonin levels in the PFC and hippocampus of rat dams.
    Neuroscience, 2016, 07-07, Volume: 327

    Topics: Animals; Antidepressive Agents; Brain; Depression; Depressive Disorder; Female; Fluoxetine; Hippocam

2016
In utero and lactational exposure to fluoxetine delays puberty onset in female rats offspring.
    Reproductive toxicology (Elmsford, N.Y.), 2016, Volume: 62

    Topics: Animals; Antidepressive Agents, Second-Generation; Estradiol; Estrous Cycle; Female; Fertility; Fluo

2016
Fluoxetine normalizes the effects of prenatal maternal stress on depression- and anxiety-like behaviors in mouse dams and male offspring.
    Behavioural brain research, 2016, 09-15, Volume: 311

    Topics: Animals; Animals, Newborn; Anxiety Disorders; Corticosterone; Depressive Disorder; Disease Models, A

2016
Prenatal SSRI alters the hormonal and behavioral responses to stress in female mice: Possible role for glucocorticoid resistance.
    Hormones and behavior, 2016, Volume: 84

    Topics: Animals; Anxiety; Behavior, Animal; Corticosterone; Female; Fluoxetine; Hypothalamo-Hypophyseal Syst

2016
Increased symptoms of illness following prenatal stress: Can it be prevented by fluoxetine?
    Behavioural brain research, 2017, 01-15, Volume: 317

    Topics: Age Factors; Analysis of Variance; Animals; Body Weight; Disease Models, Animal; Eating; Female; Flu

2017
Circadian behavior of adult mice exposed to stress and fluoxetine during development.
    Psychopharmacology, 2017, Volume: 234, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Circadian Rhythm; Female; Fluoxet

2017
Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:2

    Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder; Female; Fluoxetine; Gene Expression; Imi

2017
Prolonged neonatal complications after in utero exposure to fluoxetine.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2008, Volume: 21, Issue:12

    Topics: Adult; Diagnosis, Differential; Female; Fluoxetine; Humans; Infant, Newborn; Neonatal Abstinence Syn

2008
Fluoxetine administration to pregnant rats increases anxiety-related behavior in the offspring.
    Psychopharmacology, 2011, Volume: 217, Issue:3

    Topics: Animals; Anxiety; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Female; Fluoxetine;

2011
[Influence of fluoxetine and paroxetine on anxiety-like behavior in young and adult prenatally stressed male rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:4

    Topics: Age Factors; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Behavi

2011
Serotonin transporter occupancy in rats exposed to serotonin reuptake inhibitors in utero or via breast milk.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:1

    Topics: Aging; Animals; Anxiety; Brain; Central Nervous System; Female; Fetus; Fluoxetine; Image Processing,

2011
Mother-infant antidepressant concentrations, maternal depression, and perinatal events.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:7

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Dose-Res

2011
Prenatal fluoxetine exposure induces life-long serotonin 5-HT₃ receptor-dependent cortical abnormalities and anxiety-like behaviour.
    Neuropharmacology, 2012, Volume: 62, Issue:2

    Topics: Animals; Anxiety; Behavior, Animal; Cerebral Cortex; Female; Fluoxetine; Mice; Neurons; Pregnancy; P

2012
Prenatal lipopolysaccharide exposure increases anxiety-like behaviors and enhances stress-induced corticosterone responses in adult rats.
    Brain, behavior, and immunity, 2012, Volume: 26, Issue:3

    Topics: Animals; Anxiety; Anxiety Disorders; Brain; Corticosterone; Dopamine; Female; Fluoxetine; Hippocampu

2012
Fluoxetine and aripiprazole treatment following prenatal immune activation exert longstanding effects on rat locomotor response.
    Physiology & behavior, 2012, May-15, Volume: 106, Issue:2

    Topics: Acute-Phase Reaction; Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Disease Models, Anim

2012
Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone.
    Neuropharmacology, 2012, Volume: 63, Issue:2

    Topics: Animals; Behavior, Animal; Dexamethasone; Early Medical Intervention; Female; Fluoxetine; Glucocorti

2012
Could maternal exposure to the antidepressants fluoxetine and St. John's Wort induce long-term reproductive effects on male rats?
    Reproductive toxicology (Elmsford, N.Y.), 2013, Volume: 35

    Topics: Animals; Antidepressive Agents; Female; Fluoxetine; Hypericum; Male; Maternal-Fetal Exchange; Pregna

2013
The effects of perinatal fluoxetine treatment on the circadian system of the adult mouse.
    Psychopharmacology, 2013, Volume: 225, Issue:3

    Topics: Animals; Behavior, Animal; Circadian Clocks; Darkness; Female; Fluoxetine; Gestational Age; Light; M

2013
Behavioural outcomes of perinatal maternal fluoxetine treatment.
    Neuroscience, 2012, Dec-13, Volume: 226

    Topics: Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Behavior, Animal; Body Weight;

2012
Developmental fluoxetine exposure and prenatal stress alter sexual differentiation of the brain and reproductive behavior in male rat offspring.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:9

    Topics: Anal Canal; Animals; Brain; Ejaculation; Estradiol; Female; Fluoxetine; Genitalia, Male; Male; Midli

2013
Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study.
    The American journal of psychiatry, 2002, Volume: 159, Issue:11

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Child; Child Behavior; Child, Preschool; De

2002
Differential serotonergic inhibition of in vitro striatal [3H]acetylcholine release in prenatally cocaine-exposed male and female rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:7-8

    Topics: Acetylcholine; Animals; Cocaine; Dopamine Uptake Inhibitors; Female; Fluoxetine; Male; Pregnancy; Pr

2002
Birth outcomes after prenatal exposure to antidepressant medication.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:3

    Topics: Abnormalities, Drug-Induced; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation;

2003
Serotonergic symptoms in neonates exposed to SSRIs during pregnancy.
    The Australian and New Zealand journal of psychiatry, 2003, Volume: 37, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Depression; Female; Fluoxetine; Humans; Infant, Newborn; Pre

2003
Long-term effects of fluoxetine or vehicle administration during pregnancy on behavioral outcomes in guinea pig offspring.
    Psychopharmacology, 2005, Volume: 178, Issue:2-3

    Topics: Animals; Disease Models, Animal; Female; Fluoxetine; Guinea Pigs; Pain Threshold; Pregnancy; Prenata

2005
Prolonged QT interval in an infant of a fluoxetine treated mother.
    Archives of disease in childhood, 2005, Volume: 90, Issue:9

    Topics: Antidepressive Agents, Second-Generation; Depressive Disorder; Electrocardiography; Female; Fluoxeti

2005
Neonatal signs after in utero exposure to selective serotonin reuptake inhibitors.
    JAMA, 2005, Nov-09, Volume: 294, Issue:18

    Topics: Female; Fluoxetine; Humans; Infant Behavior; Infant, Newborn; Infant, Newborn, Diseases; Pregnancy;

2005
Fluoxetine withdrawal syndrome in the newborn.
    Indian pediatrics, 2006, Volume: 43, Issue:1

    Topics: Depressive Disorder; Female; Fluoxetine; Follow-Up Studies; Humans; Infant, Newborn; Neonatal Abstin

2006
Developmental and behavioral consequences of prenatal fluoxetine.
    Pharmacology, 2007, Volume: 79, Issue:1

    Topics: Administration, Oral; Animals; Animals, Newborn; Behavior, Animal; Birth Weight; Dose-Response Relat

2007
Behavioral evaluation of male and female mice pups exposed to fluoxetine during pregnancy and lactation.
    Pharmacology, 2007, Volume: 80, Issue:1

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Female; F

2007
Prenatal exposure to fluoxetine induces fetal pulmonary hypertension in the rat.
    American journal of respiratory and critical care medicine, 2007, Nov-15, Volume: 176, Issue:10

    Topics: Animals; Antidepressive Agents, Second-Generation; Female; Fetal Diseases; Fluoxetine; Gestational A

2007
Teratogenic effects of maternal antidepressant exposure on neural substrates of drug-seeking behavior in offspring.
    Addiction biology, 2008, Volume: 13, Issue:1

    Topics: Amygdala; Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Arousal; Brain; Cell

2008
Sex mediates dopamine and adrenergic receptor expression in adult rats exposed prenatally to cocaine.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2007, Volume: 25, Issue:7

    Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain Chemistry

2007
Poor neonatal adaptation in term infant. Fluoxetine toxicity.
    Pediatric annals, 2008, Volume: 37, Issue:3

    Topics: Depression; Female; Fluoxetine; Humans; Infant, Newborn; Male; Maternal Welfare; Pregnancy; Prenatal

2008
Altered water-maze search behavior in adult guinea pigs following chronic prenatal ethanol exposure: lack of mitigation by postnatal fluoxetine treatment.
    Behavioural brain research, 2008, Aug-22, Volume: 191, Issue:2

    Topics: Alcohol-Induced Disorders, Nervous System; Animals; Body Weight; Drug Interactions; Eating; Electric

2008
Maternal exposure to the antidepressant fluoxetine impairs sexual motivation in adult male mice.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:3

    Topics: Animals; Body Weight; Copulation; Female; Fluoxetine; Genitalia, Male; Lactation; Male; Mice; Motiva

2008
Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury.
    Journal of neurochemistry, 2008, Volume: 106, Issue:3

    Topics: Animals; Brain-Derived Neurotrophic Factor; Depression; Epigenesis, Genetic; Female; Fluoxetine; Gen

2008
A developmental neurotoxicity evaluation of the effects of prenatal exposure to fluoxetine in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 23, Issue:2

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Female; Fluoxetine; Litter Size; Male; Motor Activity

1994
Delayed decreases in brain 5-hydroxytryptamine2A/2C receptor density and function in male rat progeny following prenatal fluoxetine.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:2

    Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Cerebral Cortex; Female; Fluoxetine; Hypothalamu

1994
Fluoxetine hydrochloride (Prozac) toxicity in a neonate.
    Pediatrics, 1993, Volume: 92, Issue:5

    Topics: Female; Fluoxetine; Humans; Infant, Newborn; Male; Pregnancy; Prenatal Exposure Delayed Effects

1993
Effects of third trimester fluoxetine exposure on the newborn.
    Journal of clinical psychopharmacology, 1995, Volume: 15, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; D

1995
Gender-related differences exist in cortical [3H]nisoxetine binding and are not affected by prenatal morphine exposure.
    Neuroscience, 1997, Volume: 76, Issue:2

    Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Female; Fluoxetine; Hypothalamus; Kinetics; Male; Morp

1997
Effects of prenatal cocaine exposure on serotonin and norepinephrine transporter density in the rat brain.
    Annals of the New York Academy of Sciences, 1998, Jun-21, Volume: 846

    Topics: Aging; Animals; Brain; Carrier Proteins; Cocaine; Female; Fluoxetine; Male; Membrane Glycoproteins;

1998
Postnatal development of rats exposed to fluoxetine or venlafaxine during the third week of pregnancy.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1999, Volume: 32, Issue:1

    Topics: Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Birth Weight; Body Weight; Cycl

1999
Effect of prenatal diazepam, phenobarbital, haloperidol and fluoxetine exposure on foot shock induced aggression in rats.
    Indian journal of experimental biology, 1998, Volume: 36, Issue:10

    Topics: Aggression; Animals; Diazepam; Drug Evaluation, Preclinical; Electroshock; Female; Fluoxetine; Halop

1998
Reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure.
    Brain research, 2002, Mar-01, Volume: 929, Issue:1

    Topics: Animals; Animals, Newborn; Citalopram; Cocaine; Cocaine-Related Disorders; Electric Stimulation; Fem

2002