fluoxetine has been researched along with Death, Sudden in 7 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "DBA mice exhibit seizure-induced respiratory arrest (S-IRA), leading to cardiac arrest and subsequent sudden death after generalized audiogenic seizures (AGSs)." | 2.55 | Abnormalities of serotonergic neurotransmission in animal models of SUDEP. ( Faingold, CL; Feng, HJ, 2017) |
| " Selective serotonin reuptake inhibitors, while instructive with regard to mechanism, require impractical dosing and may carry additional risk in the form of greater challenges for resuscitation." | 1.56 | An oxygen-rich atmosphere or systemic fluoxetine extend the time to respiratory arrest in a rat model of obstructive apnea. ( Banerjee, A; Gurevich, R; Kollmar, R; Mooney, S; Silverman, JB; Stewart, M; Sundaram, K; Tromblee, J, 2020) |
| "Each was an elderly white female with pulmonary disease and atrial arrhythmias, including atrial fibrillation, and each was prescribed diuretics, nitrates, and other cardiac and/or pulmonary agents." | 1.28 | Unexpected deaths in depressed medical inpatients treated with fluoxetine. ( Frontera, MA; Spier, SA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Mooney, S | 1 |
| Kollmar, R | 1 |
| Gurevich, R | 1 |
| Tromblee, J | 1 |
| Banerjee, A | 1 |
| Sundaram, K | 1 |
| Silverman, JB | 1 |
| Stewart, M | 1 |
| Zeng, C | 1 |
| Long, X | 1 |
| Cotten, JF | 1 |
| Forman, SA | 1 |
| Solt, K | 1 |
| Faingold, CL | 5 |
| Feng, HJ | 2 |
| Tupal, S | 2 |
| Randall, M | 2 |
| Mhaskar, Y | 1 |
| Uteshev, VV | 1 |
| Spier, SA | 1 |
| Frontera, MA | 1 |
1 review available for fluoxetine and Death, Sudden
| Article | Year |
|---|---|
Abnormalities of serotonergic neurotransmission in animal models of SUDEP.
Topics: Animals; Brain Stem; Death, Sudden; Disease Models, Animal; Epilepsy, Reflex; Fluoxetine; Humans; Ma | 2017 |
6 other studies available for fluoxetine and Death, Sudden
| Article | Year |
|---|---|
An oxygen-rich atmosphere or systemic fluoxetine extend the time to respiratory arrest in a rat model of obstructive apnea.
Topics: Animals; Death, Sudden; Fluoxetine; Male; Oxygen; Rats, Sprague-Dawley; Respiration; Seizures; Selec | 2020 |
Fluoxetine prevents respiratory arrest without enhancing ventilation in DBA/1 mice.
Topics: Animals; Death, Sudden; Disease Models, Animal; Epilepsy; Fluoxetine; Mice; Mice, Inbred DBA; Pulmon | 2015 |
Prevention of seizure-induced sudden death in a chronic SUDEP model by semichronic administration of a selective serotonin reuptake inhibitor.
Topics: Acoustic Stimulation; Animals; Chi-Square Distribution; Death, Sudden; Death, Sudden, Cardiac; Disea | 2011 |
Differences in serotonin receptor expression in the brainstem may explain the differential ability of a serotonin agonist to block seizure-induced sudden death in DBA/2 vs. DBA/1 mice.
Topics: Animals; Brain Stem; Death, Sudden; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxe | 2011 |
Evidence supporting a role of serotonin in modulation of sudden death induced by seizures in DBA/2 mice.
Topics: Animals; Cyproheptadine; Death, Sudden; Disease Models, Animal; Dose-Response Relationship, Drug; Ep | 2006 |
Unexpected deaths in depressed medical inpatients treated with fluoxetine.
Topics: Aged; Arrhythmias, Cardiac; Death, Sudden; Depressive Disorder; Female; Fluoxetine; Humans; Inpatien | 1991 |