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fluoxetine and Colitis

fluoxetine has been researched along with Colitis in 8 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"We aimed to study the effect of fluoxetine on chronic colitis and its anti-inflammatory mechanism in interleukin-10-deficient (IL-10(-/-)) mice."7.81Fluoxetine inhibits hyperresponsive lamina propria mononuclear cells and bone marrow-derived dendritic cells, and ameliorates chronic colitis in IL-10-deficient mice. ( Im, JP; Kim, BG; Kim, JS; Kim, JW; Koh, SJ; Lee, KL, 2015)
"Pretreatment with fluoxetine attenuated the increased IκB kinase (IKK) and IκBα phosphorylation induced by TNF-α."5.37Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice. ( Jung, HC; Kim, IK; Kim, JM; Kim, JS; Kim, N; Koh, SJ; Song, IS, 2011)
"We aimed to study the effect of fluoxetine on chronic colitis and its anti-inflammatory mechanism in interleukin-10-deficient (IL-10(-/-)) mice."3.81Fluoxetine inhibits hyperresponsive lamina propria mononuclear cells and bone marrow-derived dendritic cells, and ameliorates chronic colitis in IL-10-deficient mice. ( Im, JP; Kim, BG; Kim, JS; Kim, JW; Koh, SJ; Lee, KL, 2015)
"The present study was designed to compare the anti-inflammatory and antioxidant effects of two antidepressant drugs, desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-5H-dibenz-[b,f]azepine monohydrochloride] and fluoxetine [N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine], administered with variable doses, on experimentally induced colitis in rats."3.74Do desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-5H-dibenz[b,f]azepine monohydrochloride] and fluoxetine [N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine] ameliorate the extent of colonic damage induced by acetic acid in rats? ( Baraka, AM; El Din, NM; El Said Darwish, I; Guemei, AA, 2008)
"Pretreatment with fluoxetine attenuated the increased IκB kinase (IKK) and IκBα phosphorylation induced by TNF-α."1.37Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice. ( Jung, HC; Kim, IK; Kim, JM; Kim, JS; Kim, N; Koh, SJ; Song, IS, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Prowse, KL1
Law, H1
Raez-Villanueva, S1
Markovic, F1
Wang, M1
Borojevic, R1
Parsons, SP1
Vincent, AD1
Holloway, AC1
Ratcliffe, EM1
Joo, MK1
Shin, YJ1
Kim, DH1
Koh, SJ2
Kim, JW1
Kim, BG1
Lee, KL1
Im, JP1
Kim, JS2
Bardet, R1
Moreno, JP1
Rodriguez, T1
Trémeau, AL1
Hernandez, É1
Bolot, AL1
Guemei, AA1
El Din, NM1
Baraka, AM1
El Said Darwish, I1
Bertrand, PP1
Barajas-Espinosa, A1
Neshat, S1
Bertrand, RL1
Lomax, AE1
Kim, JM1
Kim, IK1
Kim, N1
Jung, HC1
Song, IS1
Schwartz, CE1

Other Studies

8 other studies available for fluoxetine and Colitis

ArticleYear
Effects of in utero exposure to fluoxetine on the gastrointestinal tract of rat offspring.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 12-01, Volume: 325, Issue:6

    Topics: Animals; Colitis; Female; Fluoxetine; Humans; Inflammation; Male; Pregnancy; Prenatal Exposure Delay

2023
Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice.
    Scientific reports, 2023, 09-19, Volume: 13, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Cefaclor; Colitis; Depression; Dysbiosis; Fluoxetine; Mice; Serotoni

2023
Fluoxetine inhibits hyperresponsive lamina propria mononuclear cells and bone marrow-derived dendritic cells, and ameliorates chronic colitis in IL-10-deficient mice.
    Digestive diseases and sciences, 2015, Volume: 60, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Bone Marrow Cells; Chronic Disease; Colitis; Cytokines; Dendritic

2015
[A resistant diarrhea].
    Presse medicale (Paris, France : 1983), 2016, Volume: 45, Issue:3

    Topics: Aged, 80 and over; Anti-Ulcer Agents; Antidepressive Agents; Antidiarrheals; Colitis; Comorbidity; D

2016
Do desipramine [10,11-dihydro-5-[3-(methylamino) propyl]-5H-dibenz[b,f]azepine monohydrochloride] and fluoxetine [N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine] ameliorate the extent of colonic damage induced by acetic acid in rats?
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:3

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Desipramine; Dose-Response Re

2008
Analysis of real-time serotonin (5-HT) availability during experimental colitis in mouse.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:3

    Topics: Animals; Cell Count; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Electrochemistry; Elec

2010
Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Fluoxetine; Humans;

2011
A surfeit of serotonin: sumatriptan and serotonergic antidepressants.
    Archives of internal medicine, 1999, May-24, Volume: 159, Issue:10

    Topics: Antidepressive Agents, Second-Generation; Colitis; Depressive Disorder; Drug Synergism; Fluoxetine;

1999