Page last updated: 2024-10-27

fluoxetine and Cognitive Dysfunction

fluoxetine has been researched along with Cognitive Dysfunction in 10 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.

Research Excerpts

ExcerptRelevanceReference
" The aim of the study is to verify whether LAC can have an antidepressant action in a population of elderly patients with dysthymic disorder in comparison with a traditional antidepressant such as fluoxetine."9.17L-Acetylcarnitine in dysthymic disorder in elderly patients: a double-blind, multicenter, controlled randomized study vs. fluoxetine. ( Bersani, FS; Bersani, G; Colletti, C; Denaro, A; Koverech, A; Liberati, D; Meco, G; Nicolai, R, 2013)
"Radiation therapy and concomitant temozolomide chemotherapy are commonly used in treatment of brain tumors, but they may also result in behavioral impairments such as anxiety and cognitive deficit."7.91Fluoxetine reverses brain radiation and temozolomide-induced anxiety and spatial learning and memory defect in mice. ( Chai, D; Gan, H; Wu, S; Zhang, Q; Zhu, B, 2019)
"Depression was induced via six weeks of CUMS in male ICR mice, and drug therapy was given simultaneously for the last three weeks."5.62Baicalin ameliorates chronic unpredictable mild stress-induced depression through the BDNF/ERK/CREB signaling pathway. ( Cao, Z; Chen, Y; Chu, L; Jia, Z; Lu, Y; Pei, L; Yang, J; Zhang, J; Zhang, S; Zhao, J, 2021)
" The aim of the study is to verify whether LAC can have an antidepressant action in a population of elderly patients with dysthymic disorder in comparison with a traditional antidepressant such as fluoxetine."5.17L-Acetylcarnitine in dysthymic disorder in elderly patients: a double-blind, multicenter, controlled randomized study vs. fluoxetine. ( Bersani, FS; Bersani, G; Colletti, C; Denaro, A; Koverech, A; Liberati, D; Meco, G; Nicolai, R, 2013)
"Radiation therapy and concomitant temozolomide chemotherapy are commonly used in treatment of brain tumors, but they may also result in behavioral impairments such as anxiety and cognitive deficit."3.91Fluoxetine reverses brain radiation and temozolomide-induced anxiety and spatial learning and memory defect in mice. ( Chai, D; Gan, H; Wu, S; Zhang, Q; Zhu, B, 2019)
"Depression is a disabling psychiatric disorder affecting millions of people all around the world."1.62SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class. ( Amini-Khoei, H; Dehpour, AR; Ershadi, ASB; Hosseini, MJ, 2021)
"Cognitive decline is a common clinical symptom in Parkinson's disease (PD) patients."1.62Fluoxetine tunes the abnormal hippocampal oscillations in association with cognitive impairments in 6-OHDA lesioned rats. ( Feng, H; Liu, W; Zhang, R; Zhu, H, 2021)
"Depression was induced via six weeks of CUMS in male ICR mice, and drug therapy was given simultaneously for the last three weeks."1.62Baicalin ameliorates chronic unpredictable mild stress-induced depression through the BDNF/ERK/CREB signaling pathway. ( Cao, Z; Chen, Y; Chu, L; Jia, Z; Lu, Y; Pei, L; Yang, J; Zhang, J; Zhang, S; Zhao, J, 2021)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (40.00)24.3611
2020's6 (60.00)2.80

Authors

AuthorsStudies
Almeida, OP1
Hankey, GJ1
Ford, A1
Etherton-Beer, C1
Flicker, L1
Hackett, ML1
Laureano-Melo, R1
Dos-Santos, RC1
da Conceição, RR1
de Souza, JS1
da Silva Lau, R1
da Silva Souza Silva, S1
Marinho, BG1
Giannocco, G1
Ahmed, RG1
da Silva Côrtes, W1
Ershadi, ASB1
Amini-Khoei, H1
Hosseini, MJ1
Dehpour, AR1
Liu, W1
Zhang, R1
Feng, H1
Zhu, H1
Viktorisson, A1
Andersson, EM1
Lundström, E1
Sunnerhagen, KS1
Jia, Z1
Yang, J1
Cao, Z1
Zhao, J1
Zhang, J1
Lu, Y1
Chu, L1
Zhang, S1
Chen, Y1
Pei, L1
Gan, H1
Zhang, Q1
Zhu, B1
Wu, S1
Chai, D1
Zhou, CN1
Chao, FL1
Zhang, Y1
Jiang, L1
Zhang, L1
Fan, JH1
Wu, YX1
Dou, XY1
Tang, Y1
Gunlicks-Stoessel, M1
Eckshtain, D1
Lee, S1
Reigstad, K1
Mufson, L1
Weisz, J1
Bersani, G1
Meco, G1
Denaro, A1
Liberati, D1
Colletti, C1
Nicolai, R1
Bersani, FS1
Koverech, A1

Trials

4 trials available for fluoxetine and Cognitive Dysfunction

ArticleYear
Cognitive Impairment After Stroke and Treatment With Fluoxetine: A Planned Analysis of the AFFINITY Randomized Controlled Trial.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2022, Volume: 30, Issue:12

    Topics: Cognitive Dysfunction; Double-Blind Method; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibit

2022
Levels of physical activity before and after stroke in relation to early cognitive function.
    Scientific reports, 2021, 04-27, Volume: 11, Issue:1

    Topics: Aged; Cognition; Cognitive Dysfunction; Exercise; Female; Fluoxetine; Humans; Longitudinal Studies;

2021
Latent Profiles of Cognitive and Interpersonal Risk Factors for Adolescent Depression and Implications for Personalized Treatment.
    Journal of abnormal child psychology, 2019, Volume: 47, Issue:12

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Child; Cognitive Behavioral Therapy; Cognitive

2019
L-Acetylcarnitine in dysthymic disorder in elderly patients: a double-blind, multicenter, controlled randomized study vs. fluoxetine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013, Volume: 23, Issue:10

    Topics: Acetylcarnitine; Aged; Aged, 80 and over; Aging; Antidepressive Agents; Cognitive Dysfunction; Diagn

2013

Other Studies

6 other studies available for fluoxetine and Cognitive Dysfunction

ArticleYear
Perinatal fluoxetine treatment promotes long-term behavioral changes in adult mice.
    Metabolic brain disease, 2020, Volume: 35, Issue:8

    Topics: Animals; Animals, Newborn; Anxiety; Cognitive Dysfunction; Female; Fluoxetine; Hippocampus; Male; Mi

2020
SAHA Improves Depressive Symptoms, Cognitive Impairment and Oxidative Stress: Rise of a New Antidepressant Class.
    Neurochemical research, 2021, Volume: 46, Issue:5

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Cognitive Dysfunction; Depression; Female; Fluoxet

2021
Fluoxetine tunes the abnormal hippocampal oscillations in association with cognitive impairments in 6-OHDA lesioned rats.
    Behavioural brain research, 2021, 07-09, Volume: 409

    Topics: Adrenergic Agents; Animals; Behavior, Animal; Brain Waves; Cognitive Dysfunction; Disease Models, An

2021
Baicalin ameliorates chronic unpredictable mild stress-induced depression through the BDNF/ERK/CREB signaling pathway.
    Behavioural brain research, 2021, 09-24, Volume: 414

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognitive Dysfu

2021
Fluoxetine reverses brain radiation and temozolomide-induced anxiety and spatial learning and memory defect in mice.
    Journal of neurophysiology, 2019, 01-01, Volume: 121, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents, Alkylating; Anxiety; Brain Diseases; Chemoradio

2019
Fluoxetine delays the cognitive function decline and synaptic changes in a transgenic mouse model of early Alzheimer's disease.
    The Journal of comparative neurology, 2019, 06-01, Volume: 527, Issue:8

    Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Dendritic Spines; Disease Models, Animal; Fluoxet

2019