fluoxetine has been researched along with Chronic Pain in 8 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, pain sensitivity was assessed in a mouse model of anxiety/depression on the basis of chronic corticosterone (CORT) administration through the drinking water (CORT model)." | 7.78 | Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. ( Coudoré, F; David, DJ; Gardier, AM; Guiard, BP; Hache, G; Le Dantec, Y; Orvoën, S, 2012) |
| "Using a depression comorbidity of chronic pain rat model induced by spinal nerve ligation (SNL), we investigated the potency of T10 for the treatment of comorbid depression in comparison with a widely used antidepressant, fluoxetine (FLX)." | 5.46 | The novel and potent anti-depressive action of triptolide and its influences on hippocampal neuroinflammation in a rat model of depression comorbidity of chronic pain. ( Dong, Y; Hu, X; Jin, X; Li, J; Shi, J; Zhang, C; Zhang, T; Zhao, J, 2017) |
| "Co-administration of pioglitazone or metformin with low-dose fluoxetine improved mechanical allodynia, thermal hyperalgesia, and neurohistopathological changes while co-administration of pioglitazone, but not metformin, improved the depressive-like behavior in the peripheral nerve injury model of neuropathic pain in rats." | 3.81 | Co-Administration of Pioglitazone Improves Fluoxetine's Antinociceptive, Neuroprotective, and Antidepressant Effects in Chronic Constriction Injury in Rats. ( Ayuob, N; Murad, H, 2015) |
| " In the present study, pain sensitivity was assessed in a mouse model of anxiety/depression on the basis of chronic corticosterone (CORT) administration through the drinking water (CORT model)." | 3.78 | Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression. ( Coudoré, F; David, DJ; Gardier, AM; Guiard, BP; Hache, G; Le Dantec, Y; Orvoën, S, 2012) |
| "Depression is frequently associated with chronic pain or chronic stress." | 1.46 | Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression. ( Barrot, M; Barthas, F; Belzung, C; Boutillier, AL; Gilsbach, R; Hein, L; Humo, M; Karatas, M; Leman, S; Waltisperger, E; Yalcin, I, 2017) |
| "Using a depression comorbidity of chronic pain rat model induced by spinal nerve ligation (SNL), we investigated the potency of T10 for the treatment of comorbid depression in comparison with a widely used antidepressant, fluoxetine (FLX)." | 1.46 | The novel and potent anti-depressive action of triptolide and its influences on hippocampal neuroinflammation in a rat model of depression comorbidity of chronic pain. ( Dong, Y; Hu, X; Jin, X; Li, J; Shi, J; Zhang, C; Zhang, T; Zhao, J, 2017) |
| " 10b was additionally bioavailable following oral dosing and demonstrated efficacy in rat models of acute, inflammatory, and neuropathic pain." | 1.37 | Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152). ( Adedoyin, A; Bray, JA; Deecher, DC; Fensome, A; Goldberg, JA; Harrison, J; Leventhal, L; Mann, C; Mark, L; Nogle, L; O'Neill, DJ; Spangler, TB; Sullivan, NR; Terefenko, EA; Trybulski, EJ; Uveges, AJ; Vu, A; Whiteside, GT; Zhang, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| O'Neill, DJ | 1 |
| Adedoyin, A | 1 |
| Bray, JA | 1 |
| Deecher, DC | 1 |
| Fensome, A | 1 |
| Goldberg, JA | 1 |
| Harrison, J | 1 |
| Leventhal, L | 1 |
| Mann, C | 1 |
| Mark, L | 1 |
| Nogle, L | 1 |
| Sullivan, NR | 1 |
| Spangler, TB | 1 |
| Terefenko, EA | 1 |
| Trybulski, EJ | 1 |
| Uveges, AJ | 1 |
| Vu, A | 1 |
| Whiteside, GT | 1 |
| Zhang, P | 1 |
| Nemoto, W | 3 |
| Kozak, D | 3 |
| Sotocinal, SG | 3 |
| Tansley, S | 3 |
| Bannister, K | 3 |
| Mogil, JS | 3 |
| Barthas, F | 1 |
| Humo, M | 1 |
| Gilsbach, R | 1 |
| Waltisperger, E | 1 |
| Karatas, M | 1 |
| Leman, S | 1 |
| Hein, L | 1 |
| Belzung, C | 1 |
| Boutillier, AL | 1 |
| Barrot, M | 1 |
| Yalcin, I | 1 |
| Luk, S | 1 |
| Atayee, RS | 1 |
| Ma, JD | 1 |
| Best, BM | 1 |
| Hearn, L | 1 |
| Moore, RA | 1 |
| Derry, S | 1 |
| Wiffen, PJ | 1 |
| Phillips, T | 1 |
| Murad, H | 1 |
| Ayuob, N | 1 |
| Hu, X | 1 |
| Dong, Y | 1 |
| Jin, X | 1 |
| Zhang, C | 1 |
| Zhang, T | 1 |
| Zhao, J | 1 |
| Shi, J | 1 |
| Li, J | 1 |
| Hache, G | 1 |
| Guiard, BP | 1 |
| Le Dantec, Y | 1 |
| Orvoën, S | 1 |
| David, DJ | 1 |
| Gardier, AM | 1 |
| Coudoré, F | 1 |
1 review available for fluoxetine and Chronic Pain
| Article | Year |
|---|---|
Desipramine for neuropathic pain in adults.
Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Pain; Clomipramine; Desip | 2014 |
7 other studies available for fluoxetine and Chronic Pain
| Article | Year |
|---|---|
Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).
Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Benzothiazoles; Biological Availability; Cell | 2011 |
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.
Topics: Analgesics; Animals; Chronic Pain; Fluoxetine; Hyperalgesia; Mice; Nociception; Norepinephrine; Rats | 2023 |
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.
Topics: Analgesics; Animals; Chronic Pain; Fluoxetine; Hyperalgesia; Mice; Nociception; Norepinephrine; Rats | 2023 |
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.
Topics: Analgesics; Animals; Chronic Pain; Fluoxetine; Hyperalgesia; Mice; Nociception; Norepinephrine; Rats | 2023 |
Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice.
Topics: Analgesics; Animals; Chronic Pain; Fluoxetine; Hyperalgesia; Mice; Nociception; Norepinephrine; Rats | 2023 |
Cingulate Overexpression of Mitogen-Activated Protein Kinase Phosphatase-1 as a Key Factor for Depression.
Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Pain; Depressive Disorder; Disease Models | 2017 |
Urinary diazepam metabolite distribution in a chronic pain population.
Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chronic Pain; Cytochrome P-450 | 2014 |
Co-Administration of Pioglitazone Improves Fluoxetine's Antinociceptive, Neuroprotective, and Antidepressant Effects in Chronic Constriction Injury in Rats.
Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Chronic Pain; Constriction, Pathologi | 2015 |
The novel and potent anti-depressive action of triptolide and its influences on hippocampal neuroinflammation in a rat model of depression comorbidity of chronic pain.
Topics: Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Chronic Pain; Depression; Disease Mode | 2017 |
Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Chronic Pain; Cold Temperature; Corticos | 2012 |