fluoxetine has been researched along with Chronic Illness in 142 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because fluoxetine and its primary metabolite norfluoxetine have long half-lives and flat dose-response curves, we examined the tolerability of a weekly dose and its equivalence to daily dosing during the continuation phase of treatment for major depressive disorder (MDD)." | 9.09 | Exploring treatment alternatives: weekly dosing of fluoxetine for the continuation phase of major depressive disorder. ( Burke, WJ; McArthur-Miller, DA, 2001) |
| "This study is the first double-blind placebo-controlled trial of fluoxetine for chronic daily headache (CDH) and migraine." | 9.07 | Double-blind trial of fluoxetine: chronic daily headache and migraine. ( Lake, AE; Saper, JR; Silberstein, SD; Winters, ME, 1994) |
| "Twenty-two patients meeting the criteria for borderline or schizotypal personality disorder or both participated in a prospective, nonblind 12-week trial of fluoxetine." | 9.07 | Fluoxetine in the treatment of borderline and schizotypal personality disorders. ( Calabrese, JR; Markovitz, PJ; Meltzer, HY; Schulz, SC, 1991) |
| "The current study assessed whether antidepressant and/or antinociceptive drugs, duloxetine, fluoxetine as well as (±)-8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT), are able to reverse depression-like behaviour in animals with chronic neuropathic pain." | 7.83 | Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain. ( Ceci, A; Doods, H; Hu, B; Treede, RD, 2016) |
| "We aimed to study the effect of fluoxetine on chronic colitis and its anti-inflammatory mechanism in interleukin-10-deficient (IL-10(-/-)) mice." | 7.81 | Fluoxetine inhibits hyperresponsive lamina propria mononuclear cells and bone marrow-derived dendritic cells, and ameliorates chronic colitis in IL-10-deficient mice. ( Im, JP; Kim, BG; Kim, JS; Kim, JW; Koh, SJ; Lee, KL, 2015) |
| " We compared the effects of chronic treatment with the preferential nNOS inhibitor 7-nitroindazole (7-NI) with those evoked by the conventional antidepressant fluoxetine on alterations that are considered as markers of depression (immobility in the forced swimming test, FST, decreased body weight gain and increased plasma corticosterone concentration) and cardiovascular changes caused by CVS." | 7.81 | Effects of nitric oxide synthesis inhibitor or fluoxetine treatment on depression-like state and cardiovascular changes induced by chronic variable stress in rats. ( Almeida, J; Crestani, CC; Duarte, JO; Oliveira, LA, 2015) |
| "Efficiency of fluoxetine (one of the selective serotonin reuptake inhibitors) was examined in the course of treatment of 24 patients with atypical depressions that were characterized by prevalence of either negative (12 patients) or positive (12 patients) affectivity." | 7.70 | [Effectiveness of fluoxetine (portal) in atypical depressions]. ( Andriushchenko, AV, 1998) |
| "Fluoxetine appears to be a safe and effective treatment in improving symptoms in, and the quality of life of, men with difficult CP/CPPS." | 6.76 | Fluoxetine ameliorates symptoms of refractory chronic prostatitis/chronic pelvic pain syndrome. ( Chen, J; Jiang, H; Wang, P; Wang, S; Xia, D, 2011) |
| " At the end of dosing schedule, neurobehavioral tests were conducted; followed by mechanistic evaluation through biochemical analysis, RTPCR and western blot in serum and hippocampus." | 5.48 | Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. ( Js, IC; Kv, A; Lahkar, M; Madhana, RM; Naidu, VGM; Sinha, S, 2018) |
| "Recently, depression has been envisioned as more than an alteration in neurotransmitters centered around receptor signaling pathways." | 5.46 | Fluoxetine coupled with zinc in a chronic mild stress model of depression: Providing a reservoir for optimum zinc signaling and neuronal remodeling. ( Omar, NN; Tash, RF, 2017) |
| "Fluoxetine treatment was started in the CTH group, with follow-up over a 1-year period." | 5.31 | Cluster of MMPI personality profiles in chronic tension-type headache and predictable response to Fluoxetine. ( Aguirre, J; Gallardo, R; Pareja, JA; Pérez-Miranda, M, 2000) |
| "This single-center, 12-week, double-blind, prospective, controlled-concentration study randomized 121 chronic back pain patients without major depression to active placebo (benztropine mesylate) or to predetermined low, medium, or high concentrations of desipramine (targets were 50, 110, and 150 ng/mL, respectively) or fluoxetine (targets were 100, 200, and 400 ng/mL, respectively)." | 5.12 | Efficacy of noradrenergic and serotonergic antidepressants in chronic back pain: a preliminary concentration-controlled trial. ( Abramson, I; Atkinson, JH; Capparelli, EV; Garfin, SR; Matthews, SC; Slater, MA; Wallace, MS; Zisook, S, 2007) |
| " Because fluoxetine and its primary metabolite norfluoxetine have long half-lives and flat dose-response curves, we examined the tolerability of a weekly dose and its equivalence to daily dosing during the continuation phase of treatment for major depressive disorder (MDD)." | 5.09 | Exploring treatment alternatives: weekly dosing of fluoxetine for the continuation phase of major depressive disorder. ( Burke, WJ; McArthur-Miller, DA, 2001) |
| "Acute geriatric medical inpatients with depression, randomly assigned to an 8-week double-blind placebo-controlled trial of fluoxetine." | 5.08 | Treatment of depression in the elderly: effect of physical illness on response. ( Copeland, J; Evans, M; Hammond, M; Lye, M; Wilson, K, 1997) |
| "In a randomized, double-blind, parallel study, fluoxetine and amitriptyline were compared with placebo in the treatment of chronic rheumatic pain." | 5.08 | An evaluation of antidepressants in rheumatic pain conditions. ( Naidu, MU; Prasad, VB; Rani, PU; Rao, TR; Shobha, JC, 1996) |
| "This study is the first double-blind placebo-controlled trial of fluoxetine for chronic daily headache (CDH) and migraine." | 5.07 | Double-blind trial of fluoxetine: chronic daily headache and migraine. ( Lake, AE; Saper, JR; Silberstein, SD; Winters, ME, 1994) |
| "Twenty-two patients meeting the criteria for borderline or schizotypal personality disorder or both participated in a prospective, nonblind 12-week trial of fluoxetine." | 5.07 | Fluoxetine in the treatment of borderline and schizotypal personality disorders. ( Calabrese, JR; Markovitz, PJ; Meltzer, HY; Schulz, SC, 1991) |
| "The current study assessed whether antidepressant and/or antinociceptive drugs, duloxetine, fluoxetine as well as (±)-8-hydroxy-2-[di-n-propylamino] tetralin (8-OH-DPAT), are able to reverse depression-like behaviour in animals with chronic neuropathic pain." | 3.83 | Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain. ( Ceci, A; Doods, H; Hu, B; Treede, RD, 2016) |
| "We demonstrated that confronting mice to the Unpredictable Chronic Mild Stress (UCMS) procedure-a validated model of stress-induced depression-results in behavioural alterations and biochemical changes in the kynurenine pathway (KP), suspected to modify the glutamatergic neurotransmission through the imbalance between downstream metabolites such as 3-hydroxykynurenine, quinolinic and kynurenic acids." | 3.83 | Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine. ( Barone, PR; Belzung, C; Callebert, J; Guillemin, GJ; Laugeray, A; Launay, JM; Mutlu, O, 2016) |
| "We aimed to study the effect of fluoxetine on chronic colitis and its anti-inflammatory mechanism in interleukin-10-deficient (IL-10(-/-)) mice." | 3.81 | Fluoxetine inhibits hyperresponsive lamina propria mononuclear cells and bone marrow-derived dendritic cells, and ameliorates chronic colitis in IL-10-deficient mice. ( Im, JP; Kim, BG; Kim, JS; Kim, JW; Koh, SJ; Lee, KL, 2015) |
| " We compared the effects of chronic treatment with the preferential nNOS inhibitor 7-nitroindazole (7-NI) with those evoked by the conventional antidepressant fluoxetine on alterations that are considered as markers of depression (immobility in the forced swimming test, FST, decreased body weight gain and increased plasma corticosterone concentration) and cardiovascular changes caused by CVS." | 3.81 | Effects of nitric oxide synthesis inhibitor or fluoxetine treatment on depression-like state and cardiovascular changes induced by chronic variable stress in rats. ( Almeida, J; Crestani, CC; Duarte, JO; Oliveira, LA, 2015) |
| "EOPF, as well as fluoxetine, restored the CUMS-induced decreased sucrose preference and increased immobility time, without affecting body weight gain and locomotor activity." | 3.79 | Essential oil of Perilla frutescens-induced change in hippocampal expression of brain-derived neurotrophic factor in chronic unpredictable mild stress in mice. ( Fu, Y; Geng, D; Li, J; Liu, BB; Liu, Y; Tu, JQ; Weng, LJ; Yi, LT, 2013) |
| "Exposure to CUMS for four weeks caused depression-like behaviour in rats, as indicated by significant decreases in weight gain, sucrose consumption and locomotor activity." | 3.78 | Anti-depressant effects of Xiaoyaosan on rat model of chronic unpredictable mild stress: a plasma metabonomics study based on NMR spectroscopy. ( Cui, J; Du, GH; Gao, XX; Li, ZF; Li, ZY; Liu, XJ; Qin, XM; Sun, HF; Zhang, LZ; Zhou, YZ, 2012) |
| " The behavioral and neuroendocrinological effects of icariin, a major constituent of flavonoids isolated from Epimedium brevicornum, were investigated in the CMS model of depression in male Wistar rats." | 3.74 | Icariin from Epimedium brevicornum attenuates chronic mild stress-induced behavioral and neuroendocrinological alterations in male Wistar rats. ( Jiang, FX; Kong, LD; Kung, HF; Li, YC; Pan, Y; Xia, X, 2007) |
| "Transdermal fentanyl is an opioid analgesic that is effective on chronic pain, and which appears to be advantageous due to several factors such as ease of administration, the relatively stable serum concentration and long dose intervals." | 3.72 | Oral transmucosal abuse of transdermal fentanyl. ( Dimopoulos, NP; Gitsa, OE; Liappas, AI; Liappas, IA; Mellos, E; Rabavilas, AD, 2004) |
| " During exposure to hypoxia (10% O2 for 2 weeks), the animals received one of the specific 5-HTT inhibitors citalopram and fluoxetine (10 mg/kg/day), the selective 5-HT1B/1D receptor antagonist GR127935 (2 and 10 mg/kg/day), or the 5-HT2A receptor antagonist ketanserin (2 mg/kg/day)." | 3.72 | Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension. ( Adnot, S; Eddahibi, S; Hamon, M; Marcos, E; Nosjean, A; Pham, MH; Raffestin, B, 2003) |
| "Efficiency of fluoxetine (one of the selective serotonin reuptake inhibitors) was examined in the course of treatment of 24 patients with atypical depressions that were characterized by prevalence of either negative (12 patients) or positive (12 patients) affectivity." | 3.70 | [Effectiveness of fluoxetine (portal) in atypical depressions]. ( Andriushchenko, AV, 1998) |
| "We present two patients with a history of chronic idiopathic urticaria occurring in conjunction with a panic disorder (DSM-IIIR), in whom both the urticaria and panic disorder responded favorably to a course of the selective serotonin reuptake inhibitor antidepressants fluoxetine and sertraline, respectively." | 3.69 | Chronic idiopathic urticaria associated with panic disorder: a syndrome responsive to selective serotonin reuptake inhibitor antidepressants? ( Gupta, AK; Gupta, MA, 1995) |
| "After patients with major depressive disorder (MDD) respond to acute-phase cognitive therapy (CT), continuation-phase treatments may be applied to improve long-term outcomes." | 2.80 | Predictors of longitudinal outcomes after unstable response to acute-phase cognitive therapy for major depressive disorder. ( Clark, LA; Jarrett, RB; Thase, ME; Vittengl, JR, 2015) |
| "Fluoxetine appears to be a safe and effective treatment in improving symptoms in, and the quality of life of, men with difficult CP/CPPS." | 2.76 | Fluoxetine ameliorates symptoms of refractory chronic prostatitis/chronic pelvic pain syndrome. ( Chen, J; Jiang, H; Wang, P; Wang, S; Xia, D, 2011) |
| "Five hundred seventy persons with major depressive disorder were treated with fluoxetine for 12 weeks and their pattern of response was determined." | 2.72 | Predictors of relapse in a prospective study of fluoxetine treatment of major depression. ( Alpert, JE; Chen, Y; Cheng, J; Fava, M; McGrath, PJ; Nierenberg, AA; Petkova, E; Quitkin, FM; Stewart, JW, 2006) |
| "Greater numbers of baseline chronic illness indicated worse physical functioning, general health perceptions, and vitality and greater bodily pain and role limitation from physical problems." | 2.68 | Impact of physical illness on quality of life and antidepressant response in geriatric major depression. Fluoxetine Collaborative Study Group. ( Birkett, M; Bystritsky, A; Koran, LM; Meyers, BS; Nemeroff, CB; Small, GW, 1996) |
| "Fluoxetine treatment did not influence positive schizophrenic symptoms, while it induced a slight, but statistically significant, decrease (p < 0." | 2.67 | Adjunctive fluoxetine in the treatment of negative symptoms in chronic schizophrenic patients. ( Ancione, M; Caputi, AP; De Domenico, P; Di Rosa, AE; Gitto, C; Longobardo, N; Ruello, C; Spina, E, 1994) |
| "Depression is one of the most common forms of mental illness and also a leading cause of disability worldwide." | 1.56 | LIMK1/2 in the mPFC Plays a Role in Chronic Stress-Induced Depressive-Like Effects in Mice. ( Chen, TT; Gao, TT; Guan, W; Jiang, B; Liu, L; Wang, JL; Wang, Y; Wang, YJ; Zhao, J, 2020) |
| "Treatment with 5-hydroxytryptophan restores the levels of 5-HT and its precursors in the HpC, improves HpC neurogenesis, and alleviates despair-like symptoms." | 1.56 | Changes in Gut Microbiota by Chronic Stress Impair the Efficacy of Fluoxetine. ( Bigot, M; Chevalier, G; Eberl, G; Katsimpardi, L; Lledo, PM; Moigneu, C; Saha, S; Siopi, E, 2020) |
| "Treatment with fluoxetine 60 mg/day for 12 weeks reduced obsessive symptoms by 60%, improving her quality of life." | 1.48 | The Stuck Song Syndrome: A Case of Musical Obsessions. ( Lizarazo Rodríguez, IL; Orjuela Rojas, JM, 2018) |
| " At the end of dosing schedule, neurobehavioral tests were conducted; followed by mechanistic evaluation through biochemical analysis, RTPCR and western blot in serum and hippocampus." | 1.48 | Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice. ( Js, IC; Kv, A; Lahkar, M; Madhana, RM; Naidu, VGM; Sinha, S, 2018) |
| "Recently, depression has been envisioned as more than an alteration in neurotransmitters centered around receptor signaling pathways." | 1.46 | Fluoxetine coupled with zinc in a chronic mild stress model of depression: Providing a reservoir for optimum zinc signaling and neuronal remodeling. ( Omar, NN; Tash, RF, 2017) |
| "Harmine treatment (20mg/kg) prevented the reductions in brain-derived neurotrophic factor (BDNF) protein levels and hippocampal neurogenesis induced by CUS." | 1.46 | Harmine produces antidepressant-like effects via restoration of astrocytic functions. ( Chen, X; Gong, Y; Huang, C; Ling, Y; Liu, F; Tong, L; Wang, P; Wu, J; Zhu, L, 2017) |
| "Sulforaphane (SFN) is a natural compound with antioxidative, anti-inflammatory and neuroprotective activities." | 1.43 | Sulforaphane produces antidepressant- and anxiolytic-like effects in adult mice. ( Gao, Q; Gao, Y; Liang, Y; Ma, Y; Shi, H; Wang, X; Wu, S; Xi, Y; Zhao, P, 2016) |
| "Major depressive disorder is thought to arise in part from dysfunction of the brain's "reward circuitry", consisting of the mesolimbic dopamine system and the glutamatergic and neuromodulatory inputs onto this system." | 1.42 | Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress. ( Cooper, S; Eagle, A; Gajewski, P; Kaska, S; Mazei-Robison, M; Nestler, EJ; Robison, AJ; Thibault, M; Vialou, V, 2015) |
| " In terms of in vivo neuronal activities, a CMS-induced decrease in spontaneous firing in burst of medial prefrontal cortex pyramidal neurons rather than ventral tegmental area (VTA) was reversed by the chronic administration of fluoxetine and YY-23." | 1.40 | Burst-firing patterns in the prefrontal cortex underlying the neuronal mechanisms of depression probed by antidepressants. ( Fu, Z; Guo, F; Huang, C; Li, Y; Wu, B; Zhang, B; Zhang, Q, 2014) |
| "CD-1 mice were dosed with Bacille Calmette-Guérin (BCG) and measures of body weight, locomotor activity, and immobility in the tail suspension test (TST) were made." | 1.39 | A depressive phenotype induced by Bacille Calmette Guérin in 'susceptible' animals: sensitivity to antidepressants. ( Clark, JA; Klee, N; Nizami, M; Platt, B; Schulenberg, J, 2013) |
| " Chronic administration of etazolate (0." | 1.39 | Etazolate, a phosphodiesterase 4 inhibitor reverses chronic unpredictable mild stress-induced depression-like behavior and brain oxidative damage. ( Bhatt, S; Jindal, A; Mahesh, R, 2013) |
| "Treatment with fluoxetine (10 mg · kg(-1) · day(-1), days 36-42), tegaserod (1 mg · kg(-1) · day(-1), day 43), or the combination of both, reduced visceral hypersensitivity and plasma 5-HT levels." | 1.38 | Effect of the 5-HT4 receptor and serotonin transporter on visceral hypersensitivity in rats. ( Hua-Hong, W; Jun-Xia, L; Xin-Guang, L; Yan, C; Yi-Xuan, L, 2012) |
| "Body weight was evaluated before and after fluoxetine treatment." | 1.35 | Fluoxetine alters feeding behavior and leptin levels in chronically-stressed rats. ( Bassani, MG; Dalmaz, C; Gamaro, GD; Lopes, J; Prediger, ME, 2008) |
| "Fluoxetine was administrated to either naive rats or stressed rats for 21 days." | 1.35 | Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. ( Li, H; Li, J; Lin, W; Qi, X; Sun, M; Wang, D; Wang, W, 2008) |
| "Treatment with fluoxetine during CRS reversed the decrease in DG H3K9me3, but had no effect on the other marks." | 1.35 | Regulation of hippocampal H3 histone methylation by acute and chronic stress. ( Hunter, RG; McCarthy, KJ; McEwen, BS; Milne, TA; Pfaff, DW, 2009) |
| "Treatment of fluoxetine could reverse CUMS-induced impairment." | 1.35 | Cytoskeletal alterations in rat hippocampus following chronic unpredictable mild stress and re-exposure to acute and chronic unpredictable mild stress. ( Liu, Z; Wang, G; Wang, H; Wang, X; Yang, C, 2009) |
| "Fluoxetine treatment counteracted the inhibitory effect of stress." | 1.34 | Chronic social stress inhibits cell proliferation in the adult medial prefrontal cortex: hemispheric asymmetry and reversal by fluoxetine treatment. ( Abumaria, N; Czéh, B; Domenici, E; Fuchs, E; Hiemke, C; Müller-Keuker, JI; Rygula, R, 2007) |
| "Fluoxetine treatment prevented the stress-induced numerical decrease of astrocytes, but had no counteracting effect on somal volume shrinkage." | 1.33 | Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment. ( Czéh, B; Fuchs, E; Hiemke, C; Schmelting, B; Simon, M, 2006) |
| "Treatment with fluoxetine increased this enzyme activity and reversed the effect of stress." | 1.32 | Reduction of hippocampal Na+, K+-ATPase activity in rats subjected to an experimental model of depression. ( Dalmaz, C; Gamaro, GD; Matté, C; Prediger, ME; Streck, EL; Wyse, AT, 2003) |
| "Fluoxetine treatment was started in the CTH group, with follow-up over a 1-year period." | 1.31 | Cluster of MMPI personality profiles in chronic tension-type headache and predictable response to Fluoxetine. ( Aguirre, J; Gallardo, R; Pareja, JA; Pérez-Miranda, M, 2000) |
| "Fluoxetine treatment reverted the alterations induced by CMS." | 1.31 | Altered expression of autonomic neurotransmitter receptors and proliferative responses in lymphocytes from a chronic mild stress model of depression: effects of fluoxetine. ( Cremaschi, GA; Edgar, VA; Genaro, AM; Sterin-Borda, L, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 29 (20.42) | 18.2507 |
| 2000's | 45 (31.69) | 29.6817 |
| 2010's | 60 (42.25) | 24.3611 |
| 2020's | 8 (5.63) | 2.80 |
| Authors | Studies |
|---|---|
| Siopi, E | 1 |
| Chevalier, G | 1 |
| Katsimpardi, L | 1 |
| Saha, S | 1 |
| Bigot, M | 1 |
| Moigneu, C | 1 |
| Eberl, G | 1 |
| Lledo, PM | 1 |
| Xue, SS | 1 |
| Zhou, CH | 1 |
| Xue, F | 1 |
| Liu, L | 2 |
| Cai, YH | 1 |
| Luo, JF | 1 |
| Wang, Y | 4 |
| Tan, QR | 1 |
| Wang, HN | 1 |
| Peng, ZW | 1 |
| Cao, C | 1 |
| Liu, M | 1 |
| Qu, S | 1 |
| Huang, R | 1 |
| Qi, M | 1 |
| Zhu, Z | 1 |
| Zheng, J | 1 |
| Chen, Z | 1 |
| Wang, Z | 1 |
| Han, Z | 1 |
| Zhu, Y | 1 |
| Huang, F | 1 |
| Duan, JA | 1 |
| Stanisavljević, A | 1 |
| Perić, I | 1 |
| Gass, P | 1 |
| Inta, D | 1 |
| Lang, UE | 1 |
| Borgwardt, S | 1 |
| Filipović, D | 1 |
| Gao, TT | 1 |
| Wang, JL | 2 |
| Wang, YJ | 2 |
| Guan, W | 1 |
| Chen, TT | 1 |
| Zhao, J | 1 |
| Jiang, B | 2 |
| Hu, W | 2 |
| Xie, G | 1 |
| Zhou, T | 1 |
| Tu, J | 1 |
| Zhang, J | 1 |
| Lin, Z | 1 |
| Zhang, H | 1 |
| Gao, L | 1 |
| Yoon, DJ | 1 |
| Nguyen, C | 1 |
| Bagood, MD | 1 |
| Fregoso, DR | 1 |
| Yang, HY | 1 |
| Medina Lopez, AI | 1 |
| Crawford, RW | 1 |
| Tran, J | 1 |
| Isseroff, RR | 1 |
| Matsuda, Y | 1 |
| Ozawa, N | 1 |
| Shinozaki, T | 1 |
| Aoki, K | 1 |
| Nihonmatsu-Kikuchi, N | 1 |
| Shinba, T | 1 |
| Tatebayashi, Y | 1 |
| Liu, F | 1 |
| Wu, J | 1 |
| Gong, Y | 1 |
| Wang, P | 2 |
| Zhu, L | 1 |
| Tong, L | 1 |
| Chen, X | 1 |
| Ling, Y | 1 |
| Huang, C | 2 |
| Jiang, H | 2 |
| Meng, H | 1 |
| Lu, J | 1 |
| Li, J | 4 |
| Zhang, X | 3 |
| Yang, X | 1 |
| Zhao, B | 1 |
| Sun, Y | 1 |
| Bao, T | 1 |
| Omar, NN | 1 |
| Tash, RF | 1 |
| Ren, Y | 2 |
| Wang, H | 3 |
| Ye, Y | 1 |
| Song, L | 2 |
| Tu, MJ | 1 |
| Wang, WW | 1 |
| Yang, L | 1 |
| Song, C | 1 |
| Liu, BP | 1 |
| Zhang, YP | 1 |
| Peng, Z | 1 |
| Wang, J | 1 |
| Collier, AD | 1 |
| Echevarria, DJ | 1 |
| Savelieva, KV | 1 |
| Lawrence, RF | 1 |
| Rex, CS | 1 |
| Meshalkina, DA | 1 |
| Kalueff, AV | 1 |
| Kv, A | 1 |
| Madhana, RM | 1 |
| Js, IC | 1 |
| Lahkar, M | 1 |
| Sinha, S | 1 |
| Naidu, VGM | 1 |
| Song, Y | 1 |
| Sun, R | 1 |
| Ji, Z | 1 |
| Li, X | 1 |
| Fu, Q | 2 |
| Ma, S | 1 |
| Farooq, RK | 1 |
| Tanti, A | 1 |
| Ainouche, S | 1 |
| Roger, S | 1 |
| Belzung, C | 4 |
| Camus, V | 1 |
| Orjuela Rojas, JM | 1 |
| Lizarazo Rodríguez, IL | 1 |
| Mao, M | 1 |
| Li, S | 3 |
| Zong, M | 1 |
| Qiu, L | 1 |
| Yang, J | 2 |
| Xia, J | 1 |
| Ji, M | 1 |
| Vittengl, JR | 2 |
| Clark, LA | 2 |
| Thase, ME | 2 |
| Jarrett, RB | 2 |
| Yi, LT | 1 |
| Geng, D | 1 |
| Liu, BB | 1 |
| Fu, Y | 1 |
| Tu, JQ | 1 |
| Liu, Y | 1 |
| Weng, LJ | 1 |
| Yang, CR | 2 |
| Zhang, ZG | 1 |
| Bai, YY | 2 |
| Zhou, HF | 1 |
| Zhou, L | 2 |
| Ruan, CS | 2 |
| Li, F | 1 |
| Li, CQ | 1 |
| Zheng, HY | 1 |
| Shen, LJ | 1 |
| Zhou, XF | 2 |
| Wang, C | 1 |
| Li, M | 1 |
| Sawmiller, D | 1 |
| Fan, Y | 1 |
| Ma, Y | 2 |
| Tan, J | 1 |
| Pan, Y | 3 |
| Chen, XY | 1 |
| Zhang, QY | 2 |
| Kong, LD | 3 |
| Dhingra, D | 1 |
| Bhankher, A | 1 |
| Jedynak, P | 1 |
| Kos, T | 1 |
| Sandi, C | 1 |
| Kaczmarek, L | 1 |
| Filipkowski, RK | 1 |
| Patrício, P | 1 |
| Mateus-Pinheiro, A | 1 |
| Irmler, M | 1 |
| Alves, ND | 1 |
| Machado-Santos, AR | 1 |
| Morais, M | 1 |
| Correia, JS | 1 |
| Korostynski, M | 1 |
| Piechota, M | 1 |
| Stoffel, R | 1 |
| Beckers, J | 1 |
| Bessa, JM | 1 |
| Almeida, OF | 1 |
| Sousa, N | 1 |
| Pinto, L | 1 |
| Koh, SJ | 1 |
| Kim, JW | 1 |
| Kim, BG | 1 |
| Lee, KL | 1 |
| Im, JP | 1 |
| Kim, JS | 1 |
| Guo, F | 1 |
| Zhang, Q | 1 |
| Zhang, B | 1 |
| Fu, Z | 1 |
| Wu, B | 1 |
| Li, Y | 3 |
| Wang, CH | 1 |
| Zhang, XL | 1 |
| Wang, GD | 1 |
| Wang, XK | 1 |
| Dong, J | 1 |
| Ning, QF | 1 |
| Gupta, D | 1 |
| Radhakrishnan, M | 1 |
| Kurhe, Y | 1 |
| Thangaraj, D | 1 |
| Prabhakar, V | 1 |
| Kanade, P | 1 |
| Chen, JX | 1 |
| Yao, LH | 1 |
| Xu, BB | 1 |
| Qian, K | 1 |
| Wang, HL | 1 |
| Liu, ZC | 1 |
| Wang, XP | 1 |
| Wang, GH | 1 |
| Filho, CB | 1 |
| Jesse, CR | 1 |
| Donato, F | 1 |
| Giacomeli, R | 1 |
| Del Fabbro, L | 1 |
| da Silva Antunes, M | 1 |
| de Gomes, MG | 1 |
| Goes, AT | 1 |
| Boeira, SP | 1 |
| Prigol, M | 1 |
| Souza, LC | 1 |
| Ampuero, E | 1 |
| Luarte, A | 1 |
| Santibañez, M | 1 |
| Varas-Godoy, M | 1 |
| Toledo, J | 1 |
| Diaz-Veliz, G | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of SSRI-Resistant Depression in Adolescents (TORDIA)[NCT00018902] | Phase 2/Phase 3 | 334 participants (Actual) | Interventional | 2001-01-31 | Completed | ||
| Single Case Experimental Design (SCED) Comparing an Off-the-shelf Carbon Ankle Foot Orthosis (SPRYSTEP) Versus an off-the Shelf Standard Plastic Ankle Foot Orthosis in the Treatment of Walking Functional Impairment[NCT05131399] | 20 participants (Anticipated) | Interventional | 2022-02-28 | Recruiting | |||
| Prozac Treatment of Major Depression: Discontinuation Study[NCT00427128] | Phase 4 | 627 participants (Actual) | Interventional | 1995-11-30 | Completed | ||
| Efficacy of Antidepressants in Chronic Back Pain[NCT00018200] | Phase 2 | 130 participants (Actual) | Interventional | 1999-04-30 | Completed | ||
| Alterations in mRNA and Protein Expression in Human Peripheral Mononuclear Blood Cells (PMC) of Schizophrenia Patients Treated With Fluvoxamine Augmentation of Antipsychotics: Relationship to Clinical Symptoms and Cognitive Function[NCT00645580] | 15 participants (Anticipated) | Interventional | 2008-04-30 | Active, not recruiting | |||
| Auricular Acupuncture for Sleep Disturbances: A Randomized Control Trial[NCT04956341] | 316 participants (Anticipated) | Interventional | 2022-05-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fluoxetine and Chronic Illness
| Article | Year |
|---|---|
Management of recurrent depression.
Topics: 1-Naphthylamine; Antidepressive Agents; Chronic Disease; Combined Modality Therapy; Depressive Disor | 1993 |
26 trials available for fluoxetine and Chronic Illness
| Article | Year |
|---|---|
Predictors of longitudinal outcomes after unstable response to acute-phase cognitive therapy for major depressive disorder.
Topics: Adult; Age Factors; Antidepressive Agents, Second-Generation; Chronic Disease; Cognitive Behavioral | 2015 |
Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules.
Topics: Adult; Aged; Aorta; Cell Adhesion; Cell Survival; Chronic Disease; Citalopram; Depression; Endotheli | 2010 |
Treatment of selective serotonin reuptake inhibitor-resistant depression in adolescents: predictors and moderators of treatment response.
Topics: Adolescent; Antidepressive Agents, Second-Generation; Chronic Disease; Cognitive Behavioral Therapy; | 2009 |
Childhood neglect and abuse as predictors of antidepressant response in adult depression.
Topics: Adult; Age of Onset; Antidepressive Agents; Child; Child Abuse; Child Abuse, Sexual; Chronic Disease | 2009 |
Fluoxetine ameliorates symptoms of refractory chronic prostatitis/chronic pelvic pain syndrome.
Topics: Adult; Antidepressive Agents, Second-Generation; Chronic Disease; Fluoxetine; Humans; Male; Middle A | 2011 |
Moderators of fluoxetine treatment response for children and adolescents with comorbid depression and substance use disorders.
Topics: Adolescent; Alcoholism; Antidepressive Agents, Second-Generation; Child; Chronic Disease; Depressive | 2012 |
The relationship of personality disorders to treatment outcome in depressed outpatients.
Topics: Adult; Age Factors; Ambulatory Care; Antidepressive Agents; Chronic Disease; Comorbidity; Depressive | 2003 |
Biological markers and psychophysiological methods as long term response predictors to fluoxetine treatment.
Topics: Adrenal Cortex Hormones; Adult; Chronic Disease; Depression; Dexamethasone; Dexfenfluramine; Drug Ad | 2004 |
Clinical predictors of early fluoxetine treatment response in obsessive-compulsive disorder.
Topics: Adolescent; Adult; Age Factors; Chronic Disease; Dose-Response Relationship, Drug; Drug Administrati | 2006 |
Predictors of relapse in a prospective study of fluoxetine treatment of major depression.
Topics: Adult; Chronic Disease; Depressive Disorder, Major; Double-Blind Method; Drug Resistance; Female; Fl | 2006 |
Extreme response style in recurrent and chronically depressed patients: change with antidepressant administration and stability during continuation treatment.
Topics: Acute Disease; Adult; Chronic Disease; Cognitive Behavioral Therapy; Depressive Disorder, Major; Dos | 2007 |
Efficacy of noradrenergic and serotonergic antidepressants in chronic back pain: a preliminary concentration-controlled trial.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Back Pain; Capsules; Chronic Disease; Constipation; Desip | 2007 |
Effect of serotonergic antidepressant therapy on temperament and character scales in patients with chronic tension-type headache.
Topics: Adult; Character; Chronic Disease; Citalopram; Female; Fluoxetine; Harm Reduction; Humans; Internal- | 2007 |
Fluoxetine and migraine: comparison of double-blind trials.
Topics: Chronic Disease; Double-Blind Method; Fluoxetine; Headache; Humans; Migraine Disorders; Multivariate | 1995 |
Adjunctive fluoxetine in the treatment of negative symptoms in chronic schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Female | 1994 |
Double-blind trial of fluoxetine: chronic daily headache and migraine.
Topics: Adult; Affect; Chronic Disease; Double-Blind Method; Female; Fluoxetine; Headache; Humans; Male; Mid | 1994 |
An evaluation of antidepressants in rheumatic pain conditions.
Topics: Adult; Amitriptyline; Analgesics; Antidepressive Agents, Second-Generation; Antidepressive Agents, T | 1996 |
Impact of physical illness on quality of life and antidepressant response in geriatric major depression. Fluoxetine Collaborative Study Group.
Topics: Aged; Antidepressive Agents, Second-Generation; Chronic Disease; Comorbidity; Depressive Disorder; D | 1996 |
Six month follow-up of early-onset chronic depression.
Topics: 1-Naphthylamine; Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; | 1996 |
Treatment of depression in the elderly: effect of physical illness on response.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Chronic Disease; Depression; Doub | 1997 |
Risperidone addition in serotonin reuptake inhibitor-resistant trichotillomania: three cases.
Topics: Adult; Chronic Disease; Drug Resistance; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; | 1999 |
One year clinical and psychosocial outcomes of early-onset chronic depression.
Topics: Adult; Age Factors; Antidepressive Agents, Tricyclic; Chronic Disease; Depressive Disorder; Female; | 1999 |
Predictors of relapse during fluoxetine continuation or maintenance treatment of major depression.
Topics: Adult; Age of Onset; Chronic Disease; Depressive Disorder; Drug Administration Schedule; Female; Flu | 2000 |
Factors affecting return of symptoms 1 year after treatment in a 62-week controlled study of fluoxetine in major depression.
Topics: Adult; Chronic Disease; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Follow-Up Stud | 2001 |
Exploring treatment alternatives: weekly dosing of fluoxetine for the continuation phase of major depressive disorder.
Topics: Adult; Chronic Disease; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Drug | 2001 |
Fluoxetine in the treatment of borderline and schizotypal personality disorders.
Topics: Adult; Borderline Personality Disorder; Chronic Disease; Drug Administration Schedule; Female; Fluox | 1991 |
115 other studies available for fluoxetine and Chronic Illness
| Article | Year |
|---|---|
Changes in Gut Microbiota by Chronic Stress Impair the Efficacy of Fluoxetine.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Cell Differentiation; Chronic Disease; Depressi | 2020 |
The impact of repetitive transcranial magnetic stimulation and fluoxetine on the brain lipidome in a rat model of chronic unpredictable stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Chronic Disease; Depressive Disor | 2020 |
Chinese medicine formula Kai-Xin-San ameliorates depression-like behaviours in chronic unpredictable mild stressed mice by regulating gut microbiota-inflammation-stress system.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Chronic Disease; Cytokines; Depression; Dis | 2020 |
Fluoxetine modulates neuronal activity in stress-related limbic areas of adult rats subjected to the chronic social isolation.
Topics: Age Factors; Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Corpus Striatum; De | 2020 |
LIMK1/2 in the mPFC Plays a Role in Chronic Stress-Induced Depressive-Like Effects in Mice.
Topics: Animals; Behavior, Animal; Chronic Disease; Depression; Disease Models, Animal; Fluoxetine; Lim Kina | 2020 |
Intranasal administration of white tea alleviates the olfactory function deficit induced by chronic unpredictable mild stress.
Topics: Administration, Intranasal; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Bra | 2020 |
Topical Fluoxetine as a Potential Nonantibiotic Adjunctive Therapy for Infected Wounds.
Topics: Biofilms; Chronic Disease; Drug Therapy, Combination; Fluoxetine; Gene Expression Regulation, Bacter | 2021 |
Chronic antidepressant treatment rescues abnormally reduced REM sleep theta power in socially defeated rats.
Topics: Animals; Antidepressive Agents; Chronic Disease; Electroencephalography; Fluoxetine; Humans; Imipram | 2021 |
Harmine produces antidepressant-like effects via restoration of astrocytic functions.
Topics: Anhedonia; Animals; Antidepressive Agents; Astrocytes; Brain-Derived Neurotrophic Factor; Chronic Di | 2017 |
Genome-wide transcriptome analysis of hippocampus in rats indicated that TLR/NLR signaling pathway was involved in the pathogenisis of depressive disorder induced by chronic restraint stress.
Topics: Acupuncture Therapy; Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Depressive | 2017 |
Fluoxetine coupled with zinc in a chronic mild stress model of depression: Providing a reservoir for optimum zinc signaling and neuronal remodeling.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain; Chronic Disease; Corticosterone; Depressio | 2017 |
Antidepressant-like effects of ginsenoside Rg2 in a chronic mild stress model of depression.
Topics: Animals; Antidepressive Agents; Blotting, Western; Brain-Derived Neurotrophic Factor; Chronic Diseas | 2017 |
Modeling consequences of prolonged strong unpredictable stress in zebrafish: Complex effects on behavior and physiology.
Topics: Animals; Animals, Outbred Strains; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Anim | 2018 |
Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antioxidants; Anxiety; Chronic Disease; Co | 2018 |
Perilla aldehyde attenuates CUMS-induced depressive-like behaviors via regulating TXNIP/TRX/NLRP3 pathway in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Carrier Proteins; Caspase Inhibitors; Cell Cycle | 2018 |
A P2X7 receptor antagonist reverses behavioural alterations, microglial activation and neuroendocrine dysregulation in an unpredictable chronic mild stress (UCMS) model of depression in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Chronic Disease; Dentate Gyrus; Depression; Depres | 2018 |
The Stuck Song Syndrome: A Case of Musical Obsessions.
Topics: Adult; Chronic Disease; Female; Fluoxetine; Follow-Up Studies; Humans; Music; Obsessive-Compulsive D | 2018 |
Two-hit model of postintensive care syndrome induced by lipopolysaccharide challenge and subsequent chronic unpredictable stress in mice.
Topics: Animals; Anxiety; Chronic Disease; Cognition Disorders; Corticosterone; Critical Care; Critical Illn | 2019 |
Could Treatment Matching Patients' Beliefs About Depression Improve Outcomes?
Topics: Adult; Chronic Disease; Cognitive Behavioral Therapy; Depression; Depressive Disorder, Major; Female | 2019 |
Essential oil of Perilla frutescens-induced change in hippocampal expression of brain-derived neurotrophic factor in chronic unpredictable mild stress in mice.
Topics: alpha-Linolenic Acid; Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Brain-Derived N | 2013 |
Foraging activity is reduced in a mouse model of depression.
Topics: Animals; Antidepressive Agents; Appetitive Behavior; Body Weight; Cerebral Cortex; Chronic Disease; | 2014 |
Chronic mild stress-induced changes of risk assessment behaviors in mice are prevented by chronic treatment with fluoxetine but not diazepam.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Chronic Disease; Corticosterone; Diazepam; Fluoxetin | 2014 |
Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats.
Topics: Anhedonia; Animals; Antidepressive Agents; Calcium-Binding Proteins; Carrier Proteins; Chronic Disea | 2014 |
Behavioral and biochemical evidences for antidepressant-like activity of palmatine in mice subjected to chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents; Berberine Alkaloids; Brain; Chronic Disease; Corticosterone; Fluoxet | 2014 |
Mice with ablated adult brain neurogenesis are not impaired in antidepressant response to chronic fluoxetine.
Topics: Animals; Antidepressive Agents; Bromodeoxyuridine; Chronic Disease; Cyclin D2; Depression; Explorato | 2014 |
Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus.
Topics: Acetamides; Animals; Antidepressive Agents; Chronic Disease; Dentate Gyrus; Depressive Disorder; Dis | 2015 |
Fluoxetine inhibits hyperresponsive lamina propria mononuclear cells and bone marrow-derived dendritic cells, and ameliorates chronic colitis in IL-10-deficient mice.
Topics: Animals; Anti-Inflammatory Agents; Bone Marrow Cells; Chronic Disease; Colitis; Cytokines; Dendritic | 2015 |
Burst-firing patterns in the prefrontal cortex underlying the neuronal mechanisms of depression probed by antidepressants.
Topics: Action Potentials; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chronic Diseas | 2014 |
Role of hippocampus mitogen-activated protein kinase phosphatase-1 mRNA expression and DNA methylation in the depression of the rats with chronic unpredicted stress.
Topics: Animals; Body Weight; Chronic Disease; Depression; DNA Methylation; Dual Specificity Phosphatase 1; | 2015 |
Antidepressant-like effects of a novel 5-HT3 receptor antagonist 6z in acute and chronic murine models of depression.
Topics: Acute Disease; Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Benzothiazoles; Bioma | 2014 |
Glutamate transporter 1-mediated antidepressant-like effect in a rat model of chronic unpredictable stress.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain; Chronic Disease; Depress | 2014 |
Chronic unpredictable mild stress decreases BDNF and NGF levels and Na(+),K(+)-ATPase activity in the hippocampus and prefrontal cortex of mice: antidepressant effect of chrysin.
Topics: Animals; Antidepressive Agents; Antioxidants; Brain-Derived Neurotrophic Factor; Catalase; Chronic D | 2015 |
Two Chronic Stress Models Based on Movement Restriction in Rats Respond Selectively to Antidepressant Drugs: Aldolase C As a Potential Biomarker.
Topics: Animals; Antidepressive Agents; Chronic Disease; Depressive Disorder; Disease Models, Animal; Fluoxe | 2015 |
The effects of antidepressants "fluoxetine and imipramine" on vascular abnormalities and Toll like receptor-4 expression in diabetic and non-diabetic rats exposed to chronic stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Blood Pressure; Blood Vessels; Body | 2015 |
[Unpredictable chronic mild stress effects on antidepressants activities in forced swim test].
Topics: Adaptation, Psychological; Amitriptyline; Animals; Antidepressive Agents; Chronic Disease; Drug Admi | 2015 |
Effects of nitric oxide synthesis inhibitor or fluoxetine treatment on depression-like state and cardiovascular changes induced by chronic variable stress in rats.
Topics: Animals; Antidepressive Agents; Autonomic Nervous System; Baroreflex; Behavior, Animal; Cardiovascul | 2015 |
Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress.
Topics: Animals; Antidepressive Agents, Second-Generation; Blotting, Western; Brain; Chronic Disease; Depres | 2015 |
The Functional Study of a Chinese Herbal Compounded Antidepressant Medicine--Jie Yu Chu Fan Capsule on Chronic Unpredictable Mild Stress Mouse Model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Brain; Capsules; Chronic Disease; Dis | 2015 |
Impaired adult hippocampal neurogenesis and its partial reversal by chronic treatment of fluoxetine in a mouse model of Angelman syndrome.
Topics: Adult Stem Cells; Angelman Syndrome; Animals; Antidepressive Agents; Cell Differentiation; Cell Prol | 2015 |
Combination Therapy of Salvianolic Acid and Fluoxetine Improves the Cognitive Function of Rats with Chronic Stress-induced Depression.
Topics: Alkenes; Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Cognition Disorders; De | 2016 |
Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity.
Topics: Adult; Animals; Antidepressive Agents; Chronic Disease; Depressive Disorder; Fluoxetine; Histone Dea | 2015 |
Geraniol produces antidepressant-like effects in a chronic unpredictable mild stress mice model.
Topics: Acyclic Monoterpenes; Animals; Antidepressive Agents; Carrier Proteins; Caspase 1; Chronic Disease; | 2015 |
High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit.
Topics: Animals; Antidepressive Agents; Azepines; Benzamides; Brain-Derived Neurotrophic Factor; Central Ner | 2015 |
Sulforaphane produces antidepressant- and anxiolytic-like effects in adult mice.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Antidepressive | 2016 |
Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Neurons; Analgesics; Animals; Antidepressive Agen | 2016 |
ProBDNF Signaling Regulates Depression-Like Behaviors in Rodents under Chronic Stress.
Topics: Animals; Antibodies; Antidepressive Agents, Second-Generation; Brain; Brain-Derived Neurotrophic Fac | 2016 |
Treatment of Chronic Enterovirus Encephalitis With Fluoxetine in a Patient With X-Linked Agammaglobulinemia.
Topics: Agammaglobulinemia; Antiviral Agents; Child, Preschool; Chronic Disease; Encephalitis, Viral; Entero | 2016 |
Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine.
Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Cytokines; Depression; Fluoxetin | 2016 |
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey.
Topics: Animals; Animals, Outbred Strains; Antidepressive Agents; Antidepressive Agents, Second-Generation; | 2008 |
Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress.
Topics: Animals; Brain; Chronic Disease; Cyclic AMP Response Element-Binding Protein; Depressive Disorder; D | 2008 |
Fluoxetine directly counteracts the adverse effects of chronic stress on T cell immunity by compensatory and specific mechanisms.
Topics: Animals; Antidepressive Agents, Second-Generation; B-Lymphocytes; CD4-CD8 Ratio; CD4-Positive T-Lymp | 2009 |
Evaluation of the repeated open-space swim model of depression in the mouse.
Topics: Adaptation, Psychological; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; | 2008 |
Effects of neuronal and inducible NOS inhibitor 1-[2-(trifluoromethyl) phenyl] imidazole (TRIM) in unpredictable chronic mild stress procedure in mice.
Topics: Aggression; Animals; Behavior, Animal; Body Weight; Chronic Disease; Depressive Disorder; Enzyme Inh | 2009 |
Quantitative changes in hippocampal microvasculature of chronically stressed rats: no effect of fluoxetine treatment.
Topics: Animals; Antidepressive Agents, Second-Generation; Capillaries; Chronic Disease; Fluoxetine; Hippoca | 2010 |
Drug induced aggravation of chronic skin diseases.
Topics: Chronic Disease; Dermatitis, Exfoliative; Drug Eruptions; Fluoxetine; Follow-Up Studies; Humans; Pso | 2009 |
Effects of chronic intracerebroventricular 3,4-methylenedioxy-N-methamphetamine (MDMA) or fluoxetine on the active avoidance test in rats with or without exposure to mild chronic stress.
Topics: Analysis of Variance; Animals; Avoidance Learning; Chronic Disease; Depression; Disease Models, Anim | 2009 |
Antidepressant effects of ginseng total saponins in the forced swimming test and chronic mild stress models of depression.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Biogenic Monoamines; Brain-Derived Neurotrophi | 2009 |
Cytoskeletal alterations in rat hippocampus following chronic unpredictable mild stress and re-exposure to acute and chronic unpredictable mild stress.
Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Cytoskeleton; Depressive Disorde | 2009 |
Regulation of hippocampal H3 histone methylation by acute and chronic stress.
Topics: Acute Disease; Animals; Chronic Disease; Dentate Gyrus; Fluoxetine; Hippocampus; Histones; Lysine; M | 2009 |
Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Chronic Disease; Depression; Depr | 2010 |
DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses.
Topics: Animals; Antidepressive Agents; Chronic Disease; Dominance-Subordination; Fluoxetine; Glutamic Acid; | 2010 |
Individual (N-of-1) trials can be combined to give population comparative treatment effect estimates: methodologic considerations.
Topics: Amitriptyline; Antidepressive Agents; Bayes Theorem; Chronic Disease; Clinical Trials as Topic; Drug | 2010 |
Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action.
Topics: Action Potentials; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Benzazep | 2010 |
Chronic Cotard's syndrome: recovery from 2 years' bed-ridden status.
Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Chronic Disease; Delusions; Drug The | 2011 |
Chronic mild stress induces fluoxetine-reversible decreases in hippocampal and cerebrospinal fluid levels of the neurotrophic factor S100B and its specific receptor.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Chronic Disease; Depression; Fl | 2010 |
Pulsed light irradiation improves behavioral outcome in a rat model of chronic mild stress.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavioral Symptoms; Chronic Disease; Exercise Te | 2012 |
Anti-depressant effects of Xiaoyaosan on rat model of chronic unpredictable mild stress: a plasma metabonomics study based on NMR spectroscopy.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Biomarkers; Chronic Disease; Cyclohexanols; Depres | 2012 |
Impaired hypothalamic insulin signaling in CUMS rats: restored by icariin and fluoxetine through inhibiting CRF system.
Topics: Anhedonia; Animals; Antidepressive Agents; Arcuate Nucleus of Hypothalamus; Chronic Disease; Cortico | 2013 |
Effect of the 5-HT4 receptor and serotonin transporter on visceral hypersensitivity in rats.
Topics: Animals; Animals, Newborn; Blotting, Western; Chronic Disease; Disease Models, Animal; Enzyme-Linked | 2012 |
Evaluation of antidepressant activity of ropinirole coadministered with fluoxetine in acute and chronic behavioral models of depression in rats.
Topics: Acute Disease; Administration, Oral; Analysis of Variance; Animals; Antidepressive Agents; Behavior, | 2011 |
Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences.
Topics: Adrenal Glands; Animals; Antidepressive Agents; Body Weight; Brain; Chronic Disease; Disease Models, | 2013 |
A depressive phenotype induced by Bacille Calmette Guérin in 'susceptible' animals: sensitivity to antidepressants.
Topics: Animals; Antidepressive Agents; BCG Vaccine; Chronic Disease; Depression; Desipramine; Diazepam; Dis | 2013 |
Differential effects of chronic social stress and fluoxetine on meal patterns in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Corticosterone; Eating; Energy I | 2013 |
Etazolate, a phosphodiesterase 4 inhibitor reverses chronic unpredictable mild stress-induced depression-like behavior and brain oxidative damage.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain; Chronic Disease; Etazola | 2013 |
Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension.
Topics: Analysis of Variance; Animals; Carrier Proteins; Chronic Disease; Citalopram; Disease Models, Animal | 2003 |
Fluoxetine augmentation with olanzapine for treatment of chronic resistant depression in an elderly patient: a case report.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Depressive Disorder, Major; Dose-Respo | 2003 |
Reduction of hippocampal Na+, K+-ATPase activity in rats subjected to an experimental model of depression.
Topics: Animals; Antidepressive Agents; Chronic Disease; Depression; Eating; Female; Fluoxetine; Hippocampus | 2003 |
Fluoxetine augmentation of haloperidol in chronic schizophrenia.
Topics: Adult; Chi-Square Distribution; Chronic Disease; Drug Synergism; Female; Fluoxetine; Haloperidol; Hu | 2003 |
The impact of medical comorbidity on acute treatment in major depressive disorder.
Topics: Adult; Antidepressive Agents, Second-Generation; Chronic Disease; Comorbidity; Cost of Illness; Depr | 2003 |
Obsessive-compulsive symptoms in schizophrenia induced by risperidone and responding to fluoxetine.
Topics: Antipsychotic Agents; Chronic Disease; Fluoxetine; Humans; Male; Middle Aged; Obsessive-Compulsive D | 2003 |
Oral transmucosal abuse of transdermal fentanyl.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Chronic Disease; Depressive Disorder; Drug A | 2004 |
Chronic stress decreases the number of parvalbumin-immunoreactive interneurons in the hippocampus: prevention by treatment with a substance P receptor (NK1) antagonist.
Topics: Animals; Cell Count; Chronic Disease; Conflict, Psychological; Creatinine; Fluoxetine; Hippocampus; | 2005 |
Effects of chronic stress on methamphetamine-induced dopamine depletions in the striatum.
Topics: Animals; Antidepressive Agents, Tricyclic; Chronic Disease; Desipramine; Dopamine; Dopamine Uptake I | 2004 |
Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment.
Topics: Animals; Astrocytes; Chronic Disease; Fluoxetine; Hippocampus; Male; Neuroglia; Neuronal Plasticity; | 2006 |
Nociception- and anxiety-like behavior in rats submitted to different periods of restraint stress.
Topics: Acute Disease; Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Anxiety; Chronic Disease; C | 2006 |
Impairment of the spatial learning and memory induced by learned helplessness and chronic mild stress.
Topics: Animals; Base Sequence; Brain-Derived Neurotrophic Factor; Chronic Disease; Corticosterone; Cyclic A | 2006 |
Chronic social stress inhibits cell proliferation in the adult medial prefrontal cortex: hemispheric asymmetry and reversal by fluoxetine treatment.
Topics: Animals; Body Weight; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Cell | 2007 |
Icariin from Epimedium brevicornum attenuates chronic mild stress-induced behavioral and neuroendocrinological alterations in male Wistar rats.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Chronic Diseas | 2007 |
Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress.
Topics: Animals; Antidepressive Agents; Biological Assay; Cell Death; Cells, Cultured; Chronic Disease; Cort | 2007 |
Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression.
Topics: Amitriptyline; Animals; Anti-Inflammatory Agents; Antidepressive Agents, Tricyclic; Chronic Disease; | 2008 |
Fluoxetine alters feeding behavior and leptin levels in chronically-stressed rats.
Topics: Animals; Body Weight; Chronic Disease; Estrous Cycle; Feeding Behavior; Female; Fluoxetine; Leptin; | 2008 |
Chronic idiopathic urticaria associated with panic disorder: a syndrome responsive to selective serotonin reuptake inhibitor antidepressants?
Topics: 1-Naphthylamine; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Chronic Dis | 1995 |
Cyproheptadine in treatment-resistant chronic schizophrenics with prior negative response to fluoxetine.
Topics: Adult; Aged; Antipsychotic Agents; Chronic Disease; Cyproheptadine; Depressive Disorder; Drug Therap | 1994 |
Therapeutic efficacy of specific serotonin reuptake inhibitors (SSRIs) in dysthymia.
Topics: Adult; Chronic Disease; Depressive Disorder; Female; Fluoxetine; Humans; Male; Middle Aged; Personal | 1994 |
[Dysthymic disorder and its treatment].
Topics: Antidepressive Agents, Tricyclic; Chronic Disease; Depressive Disorder; Fluoxetine; Humans; Personal | 1993 |
Chronic hepatitis related to use of fluoxetine.
Topics: Adult; Antidepressive Agents, Second-Generation; Chemical and Drug Induced Liver Injury; Chronic Dis | 1997 |
Acute and chronic antidepressant drug treatment in the rat forced swimming test model of depression.
Topics: Acute Disease; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepress | 1997 |
Effect of acute or repeated stress on behavior and brain norepinephrine system in Wistar-Kyoto (WKY) rats.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Autoradiography; Behavior, Animal; Chronic Dise | 1997 |
[Effectiveness of fluoxetine (portal) in atypical depressions].
Topics: Adolescent; Adult; Chronic Disease; Depression; Female; Fluoxetine; Follow-Up Studies; Humans; Male; | 1998 |
Effect of fluoxetine on the plasma concentrations of clozapine and its major metabolites in patients with schizophrenia.
Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Biotransformation; Chronic Di | 1998 |
Efficacy of an Hypericum perforatum (St. John's wort) extract in preventing and reverting a condition of escape deficit in rats.
Topics: Acute Disease; Animals; Appetite; Benzazepines; Chronic Disease; Disease Models, Animal; Electroshoc | 1999 |
The effects of melatonin on the behavioural disturbances induced by chronic mild stress in C3H/He mice.
Topics: Animals; Antioxidants; Behavior, Animal; Chronic Disease; Exploratory Behavior; Fluoxetine; Male; Me | 1999 |
Cluster of MMPI personality profiles in chronic tension-type headache and predictable response to Fluoxetine.
Topics: Adult; Chronic Disease; Cluster Analysis; Female; Fluoxetine; Forecasting; Humans; Male; Middle Aged | 2000 |
A study of the antidepressant activity of Hypericum perforatum on animal models.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2001 |
[Prozac treatment of chronic tension headache].
Topics: Adolescent; Adult; Affective Symptoms; Antidepressive Agents, Second-Generation; Anxiety; Chronic Di | 1999 |
SPRINT: a brief global assessment of post-traumatic stress disorder.
Topics: Adult; Chronic Disease; Female; Fluoxetine; Humans; Male; Middle Aged; Personality Assessment; Psych | 2001 |
Long-term treatment of recurrent and chronic depression.
Topics: Antidepressive Agents; Chronic Disease; Clinical Trials as Topic; Cognitive Behavioral Therapy; Comb | 2001 |
Extending indications for long-term pharmacotherapy: opportunities and challenges.
Topics: Bulimia; Chronic Disease; Fluoxetine; Humans; Long-Term Care; Obsessive-Compulsive Disorder; Sertral | 2002 |
Altered expression of autonomic neurotransmitter receptors and proliferative responses in lymphocytes from a chronic mild stress model of depression: effects of fluoxetine.
Topics: Adrenergic beta-Antagonists; Animals; Antidepressive Agents, Second-Generation; Autonomic Nervous Sy | 2002 |
Fluoxetine and suicidal preoccupation.
Topics: Ambulatory Care; Chronic Disease; Depressive Disorder; Female; Fluoxetine; Humans; Incidence; Male; | 1992 |
Symptomatic improvement of chronic fatigue with fluoxetine in ciguatera fish poisoning.
Topics: Chronic Disease; Ciguatera Poisoning; Fatigue; Female; Fluoxetine; Foodborne Diseases; Humans; Male; | 1992 |
Fluoxetine management of chronic abdominal pain.
Topics: Abdominal Pain; Adult; Chronic Disease; Female; Fluoxetine; Humans | 1992 |
[Concomitant depression and its treatment].
Topics: Adaptation, Psychological; Adult; Aged; Aged, 80 and over; Chronic Disease; Combined Modality Therap | 1992 |
Adjunctive fluoxetine improves global function in chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Compulsive Behavior; Dose-Response Relationship, Drug; | 1990 |
Fluoxetine in chronic schizophrenia.
Topics: Amantadine; Chronic Disease; Drug Therapy, Combination; Fluoxetine; Humans; Loxapine; Male; Middle A | 1990 |