Page last updated: 2024-10-27

fluoxetine and Chemical Dependence

fluoxetine has been researched along with Chemical Dependence in 62 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine combined with CBT had greater efficacy than did placebo and CBT according to changes on the Childhood Depression Rating Scale-Revised (effect size, 0."9.12A randomized controlled trial of fluoxetine and cognitive behavioral therapy in adolescents with major depression, behavior problems, and substance use disorders. ( Davies, RD; Klein, C; Lohman, M; Mikulich-Gilbertson, SK; Riggs, PD; Stover, SK, 2007)
" The adverse event profile in obese patients, though differing slightly from that seen in depressed patients, was similar in that events observed were generally mild and well tolerated."5.27Safety of fluoxetine in the treatment of obesity. ( Zerbe, RL, 1987)
" Participants were diagnosed with depressive disorders and randomly assigned to receive directly observed therapy with fluoxetine or a referral to community mental health treatment."5.24Does substance use compromise depression treatment in persons with HIV? Findings from a randomized controlled trial. ( Bangsberg, DR; Dilley, JW; Grelotti, DJ; Hammer, GP; Karasic, DH; Sorensen, JL; Tsai, AC, 2017)
"Fluoxetine combined with CBT had greater efficacy than did placebo and CBT according to changes on the Childhood Depression Rating Scale-Revised (effect size, 0."5.12A randomized controlled trial of fluoxetine and cognitive behavioral therapy in adolescents with major depression, behavior problems, and substance use disorders. ( Davies, RD; Klein, C; Lohman, M; Mikulich-Gilbertson, SK; Riggs, PD; Stover, SK, 2007)
"Stabilised MMPs scoring over 21 on the Beck Depression Inventory were randomised to receive fluoxetine or placebo over 12 weeks."5.10A randomised, controlled trial of fluoxetine in methadone maintenance patients with depressive symptoms. ( Bell, J; Christie, MJ; Dean, AJ; Mascord, DJ; Parker, G, 2002)
"Although fluoxetine might be more effective than placebo for treating adolescent depression without major comorbidity, little is known about the response of depressive symptoms to antidepressants in adolescents with comorbid conduct disorder (CD) and substance use disorders (SUD)."5.08Fluoxetine in drug-dependent delinquents with major depression: an open trial. ( Coffman, LM; Crowley, TJ; Mikulich, SK; Riggs, PD, 1997)
" In this study, 17 patients with DSM-III-R diagnoses of major depressive disorder, alcohol dependence, and cocaine abuse were included along with 34 non-cocaine-abusing depressed alcoholics in a pharmacotherapy trial involving the SSRI antidepressant fluoxetine."5.08Fluoxetine versus placebo in depressed alcoholic cocaine abusers. ( Cornelius, JR; Daley, DC; Haskett, RF; Jones-Barlock, A; Perel, JM; Salloum, IM; Thase, ME; Upsher, C, 1998)
"Transdermal fentanyl is an opioid analgesic that is effective on chronic pain, and which appears to be advantageous due to several factors such as ease of administration, the relatively stable serum concentration and long dose intervals."3.72Oral transmucosal abuse of transdermal fentanyl. ( Dimopoulos, NP; Gitsa, OE; Liappas, AI; Liappas, IA; Mellos, E; Rabavilas, AD, 2004)
"We report nine cases where fluoxetine (FX) (20 mg/day) was added to maintenance treatment with methadone (MTD) (dose range: 30-100 mg) in addicts with affective disorders."3.69Fluoxetine addition to methadone in addicts: pharmacokinetic aspects. ( Baumann, P; Bertschy, G; Eap, CB; Powell, K, 1996)
"Fluoxetine was well tolerated in combination with methadone and did not appear to alter methadone concentrations in plasma."2.67Fluoxetine for cocaine dependence in methadone maintenance: quantitative plasma and urine cocaine/benzoylecgonine concentrations. ( Batki, SL; Jacob, P; Jones, RT; Manfredi, LB, 1993)
"Informing drug abusers in treatment regarding positive HIV-serostatus was not associated with a lower treatment-retention rate or adverse psychological reactions when counseling regarding HIV issues was integrated with drug abuse treatment."2.67Psychological reactions and retention by cocaine addicts during treatment according to HIV-serostatus: a matched-control study. ( Brown, BS; Haertzen, CA; Hess, JM; Weddington, WW, 1991)
" The adverse reactions include the "serotonin syndrome", cardiovascular complications, extrapyramidal side effects such as akathisia, dyskinesias, and parkinsonian-like syndromes and an apparently increased risk of suicidality."2.38Fluoxetine: adverse effects and drug-drug interactions. ( Messiha, FS, 1993)
"Zolpidem is an imidazopyridine hypnotic that is believed to act selectively at alpha(1) subunit-containing gamma-aminobutyric acid type A (GABA(A)) receptors and thus to have minimal abuse and dependence potential."1.32Three cases of zolpidem dependence treated with fluoxetine: the serotonin hypothesis. ( Christodoulou, GN; Dimopoulos, NP; Gitsa, OE; Liappas, AI; Liappas, IA; Malitas, PN; Nikolaou, CK, 2003)
"Because of a depressive syndrome, a 39-year-old patient received 20 mg fluoxetine per day."1.29[A case of rare side effects of certain antidepressive drugs]. ( Haenel, T; Stöckli, HR; Truog, P, 1995)
"Fluoxetine pretreatment, likewise, reduced responding in non-lesioned rats and had no observable effect in lesioned animals."1.27The effects of putative 5-hydroxytryptamine receptor active agents on D-amphetamine self-administration in controls and rats with 5,7-dihydroxytryptamine median forebrain bundle lesions. ( Leccese, AP; Lyness, WH, 1984)
" The adverse event profile in obese patients, though differing slightly from that seen in depressed patients, was similar in that events observed were generally mild and well tolerated."1.27Safety of fluoxetine in the treatment of obesity. ( Zerbe, RL, 1987)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.45)18.7374
1990's35 (56.45)18.2507
2000's15 (24.19)29.6817
2010's7 (11.29)24.3611
2020's1 (1.61)2.80

Authors

AuthorsStudies
Ikram, H1
Tasneem, S1
Perveen, S1
Zakir, R1
Jabeen Haleem, D1
Connor, DA1
Gould, TJ1
Jain, S1
Gupta, T1
Nebhinani, N1
Singhai, K1
Suthar, N1
Hinckley, JD1
Riggs, P1
Dierksen, J1
Gonsoulin, M1
Walterscheid, JP1
Grelotti, DJ1
Hammer, GP1
Dilley, JW1
Karasic, DH1
Sorensen, JL2
Bangsberg, DR1
Tsai, AC1
Gao, K1
Kemp, DE1
Ganocy, SJ1
Muzina, DJ1
Xia, G1
Findling, RL2
Calabrese, JR1
Ayala, ME1
Hirschtritt, ME1
Pagano, ME1
Christian, KM1
McNamara, NK1
Stansbrey, RJ1
Lingler, J1
Faber, JE1
Demeter, CA1
Bedoya, D1
Curry, J1
Silva, S1
Rohde, P1
Ginsburg, G1
Kennard, B1
Kratochvil, C1
Simons, A1
Kirchner, J1
May, D1
Mayes, T1
Feeny, N1
Albano, AM1
Lavanier, S1
Reinecke, M1
Jacobs, R1
Becker-Weidman, E1
Weller, E1
Emslie, G1
Walkup, J1
Kastelic, E1
Burns, B1
Wells, K1
March, J1
Dean, AJ1
Bell, J1
Mascord, DJ1
Parker, G1
Christie, MJ1
Liappas, IA2
Malitas, PN1
Dimopoulos, NP2
Gitsa, OE2
Liappas, AI2
Nikolaou, CK1
Christodoulou, GN1
Seymour, PM1
Mellos, E1
Rabavilas, AD1
Giroud, C1
Michaud, K1
Sporkert, F1
Eap, C1
Augsburger, M1
Cardinal, P1
Mangin, P1
Cornelius, JR3
Clark, DB2
Bukstein, OG1
Birmaher, B1
Salloum, IM3
Brown, SA1
Stemmelin, J1
Cohen, C1
Terranova, JP1
Lopez-Grancha, M1
Pichat, P1
Bergis, O1
Decobert, M1
Santucci, V1
Françon, D1
Alonso, R1
Stahl, SM1
Keane, P1
Avenet, P1
Scatton, B1
le Fur, G1
Griebel, G1
Greenwald, MK1
Arnold, KK1
Yager, J1
Riggs, PD2
Mikulich-Gilbertson, SK1
Davies, RD1
Lohman, M1
Klein, C1
Stover, SK1
Leccese, AP1
Lyness, WH2
Covi, L1
Hess, JM2
Kreiter, NA1
Haertzen, CA2
Polles, AG1
Smith, PO1
Petrakis, I1
Carroll, K1
Gordon, L1
Cushing, G1
Rounsaville, B1
Balon, R1
Walsh, SL1
Preston, KL1
Sullivan, JT1
Fromme, R1
Bigelow, GE1
Haenel, T1
Stöckli, HR1
Truog, P1
Tinsley, JA1
Olsen, MW1
Laroche, RR1
Palmen, MA1
McCann, UD1
Ricaurte, GA1
Freeman, H1
Kaplan, R1
Walder, J1
Messiha, FS1
Batki, SL2
Manfredi, LB2
Jacob, P2
Jones, RT2
Barrett, J1
Meehan, O1
Fahy, T1
Bertschy, G2
Eap, CB2
Powell, K2
Baumann, P2
Castañeda, R1
Levy, R1
Westreich, LM1
Sussman, N1
Belej, T1
Manji, D1
Sioutis, S1
Barros, HM1
Nobrega, JN1
Gross, R1
Higgins, ST1
Budney, AJ1
Ivanusa, Z1
Hećimović, H1
Demarin, V1
Mikulich, SK1
Coffman, LM1
Crowley, TJ1
Thase, ME1
Haskett, RF1
Daley, DC1
Jones-Barlock, A1
Upsher, C1
Perel, JM1
Behnke, K1
Wilkinson, D1
Lynch, K1
Mann, JJ1
Rodgers, TA1
Fernandes, LC1
Kilicarslan, T1
Kaplan, HL1
Tyndale, RF1
Sellers, EM1
Romach, MK1
Brooke, D1
Fudala, PJ1
Johnson, RE1
Malone, DA1
Dimeff, RJ1
Picker, W1
Lerman, A1
Hajal, F1
Nelson, JC1
Dumontet, R1
Weddington, WW1
Brown, BS1
Jerome, L1
Pollack, MH1
Rosenbaum, JF1
Bulik, CM1
Epstein, LH1
Kaye, W1
Goldman, MJ1
Grinspoon, L1
Hunter-Jones, S1
Yu, DS1
Smith, FL1
Smith, DG1
Wilcox, JA1
Zerbe, RL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Depression Treatment to Improve Antiretroviral Adherence[NCT00338767]Phase 2150 participants (Actual)Interventional2001-01-31Completed
Substance Dependent Teens - Impact of Treating Depression Study 1[NCT00061113]Phase 4126 participants (Actual)Interventional2001-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for fluoxetine and Chemical Dependence

ArticleYear
Integrated Treatment of Adolescents with Co-occurring Depression and Substance Use Disorder.
    Child and adolescent psychiatric clinics of North America, 2019, Volume: 28, Issue:3

    Topics: Adolescent; Cognitive Behavioral Therapy; Delivery of Health Care, Integrated; Depression; Fluoxetin

2019
Acute phase and five-year follow-up study of fluoxetine in adolescents with major depression and a comorbid substance use disorder: a review.
    Addictive behaviors, 2005, Volume: 30, Issue:9

    Topics: Adolescent; Alcohol Drinking; Alcoholism; Antidepressive Agents, Second-Generation; Combined Modalit

2005
Fluoxetine: adverse effects and drug-drug interactions.
    Journal of toxicology. Clinical toxicology, 1993, Volume: 31, Issue:4

    Topics: Drug Interactions; Extrapyramidal Tracts; Fluoxetine; Heart; Humans; Mental Disorders; Substance-Rel

1993
From the initial clinic contact to aftercare: a brief review of effective strategies for retaining cocaine abusers in treatment.
    NIDA research monograph, 1997, Volume: 165

    Topics: Antidepressive Agents; Appointments and Schedules; Clinical Trials as Topic; Cocaine; Desipramine; F

1997
Serotonin syndrome.
    Neuropsychiatry, neuropsychology, and behavioral neurology, 1997, Volume: 10, Issue:3

    Topics: Fluoxetine; Humans; Monoamine Oxidase Inhibitors; Nervous System Diseases; Receptors, Serotonin; Ser

1997

Trials

16 trials available for fluoxetine and Chemical Dependence

ArticleYear
Does substance use compromise depression treatment in persons with HIV? Findings from a randomized controlled trial.
    AIDS care, 2017, Volume: 29, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder; Female; Fluoxetine; HIV Infections; Humans; Ill-H

2017
Moderators of fluoxetine treatment response for children and adolescents with comorbid depression and substance use disorders.
    Journal of substance abuse treatment, 2012, Volume: 42, Issue:4

    Topics: Adolescent; Alcoholism; Antidepressive Agents, Second-Generation; Child; Chronic Disease; Depressive

2012
Onset of alcohol or substance use disorders following treatment for adolescent depression.
    Journal of consulting and clinical psychology, 2012, Volume: 80, Issue:2

    Topics: Adolescent; Antidepressive Agents; Cognitive Behavioral Therapy; Combined Modality Therapy; Depressi

2012
A randomised, controlled trial of fluoxetine in methadone maintenance patients with depressive symptoms.
    Journal of affective disorders, 2002, Volume: 72, Issue:1

    Topics: Adult; Antidepressive Agents; Comorbidity; Depression; Female; Fluoxetine; Humans; Male; Methadone;

2002
A randomized controlled trial of fluoxetine and cognitive behavioral therapy in adolescents with major depression, behavior problems, and substance use disorders.
    Archives of pediatrics & adolescent medicine, 2007, Volume: 161, Issue:11

    Topics: Adolescent; Adult; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Depression;

2007
Effects of combined fluoxetine and counseling in the outpatient treatment of cocaine abusers.
    The American journal of drug and alcohol abuse, 1995, Volume: 21, Issue:3

    Topics: Adult; Ambulatory Care; Antidepressive Agents, Second-Generation; Cocaine; Combined Modality Therapy

1995
Fluoxetine alters the effects of intravenous cocaine in humans.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:6

    Topics: Adult; Affect; Arousal; Blood Pressure; Cocaine; Dose-Response Relationship, Drug; Double-Blind Meth

1994
Fluoxetine for cocaine dependence in methadone maintenance: quantitative plasma and urine cocaine/benzoylecgonine concentrations.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:4

    Topics: Adult; Cocaine; Female; Fluoxetine; Humans; Male; Methadone; Middle Aged; Prospective Studies; Psych

1993
Fluoxetine in drug-dependent delinquents with major depression: an open trial.
    Journal of child and adolescent psychopharmacology, 1997,Summer, Volume: 7, Issue:2

    Topics: Adolescent; Antidepressive Agents; Cannabis; Conduct Disorder; Depressive Disorder; Ethanol; Fluoxet

1997
Fluoxetine versus placebo in depressed alcoholic cocaine abusers.
    Psychopharmacology bulletin, 1998, Volume: 34, Issue:1

    Topics: Adult; Alcoholism; Antidepressive Agents, Second-Generation; Cocaine; Depressive Disorder; Double-Bl

1998
Fluvoxamine and fluoxetine do not interact in the same way with the metabolism of the enantiomers of methadone.
    Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:2

    Topics: Fluoxetine; Fluvoxamine; Humans; Methadone; Narcotics; Selective Serotonin Reuptake Inhibitors; Stat

1997
Treating the substance-abusing suicidal patient.
    Annals of the New York Academy of Sciences, 2001, Volume: 932

    Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Follow-Up Studies; Humans; Male

2001
Treatment of codeine dependence with inhibitors of cytochrome P450 2D6.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:3

    Topics: Adult; Aged; Analgesics, Opioid; Codeine; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitor

2002
Weighing up the pros and cons: help-seeking by drug misusers in Baltimore, USA.
    Drug and alcohol dependence, 1992, Volume: 31, Issue:1

    Topics: Adult; Bromocriptine; Buprenorphine; Cocaine; Desipramine; Fear; Female; Fluoxetine; Humans; Male; M

1992
Psychological reactions and retention by cocaine addicts during treatment according to HIV-serostatus: a matched-control study.
    The American journal of drug and alcohol abuse, 1991, Volume: 17, Issue:3

    Topics: Adaptation, Psychological; Adult; Affect; AIDS Serodiagnosis; Amantadine; Baltimore; Cocaine; Combin

1991
Treatment of laxative abuse in a female with bulimia nervosa using an operant extinction paradigm.
    Journal of substance abuse, 1990, Volume: 2, Issue:3

    Topics: Adult; Behavior Therapy; Bulimia; Cathartics; Cognitive Behavioral Therapy; Combined Modality Therap

1990

Other Studies

41 other studies available for fluoxetine and Chemical Dependence

ArticleYear
Neurochemical and behavioral effects of fluoxetine on midazolam induce dependence in an animal model of addiction.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:5

    Topics: Animals; Behavior, Animal; Drug Interactions; Fluoxetine; Hypnotics and Sedatives; Male; Midazolam;

2021
Chronic fluoxetine ameliorates adolescent chronic nicotine exposure-induced long-term adult deficits in trace conditioning.
    Neuropharmacology, 2017, Volume: 125

    Topics: Aging; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Conditioning, Psychological; Fear; Fluox

2017
Therapeutic challenges in comorbid obsessive compulsive disorder with substance use.
    Asian journal of psychiatry, 2018, Volume: 31

    Topics: Adrenergic alpha-2 Receptor Agonists; Clonazepam; Clonidine; Combined Modality Therapy; Fluoxetine;

2018
Poor Man's Methadone: A Case Report of Loperamide Toxicity.
    The American journal of forensic medicine and pathology, 2015, Volume: 36, Issue:4

    Topics: Alprazolam; Antidiarrheals; Chromatography, Liquid; Fluoxetine; Humans; Hypertrophy; Loperamide; Mal

2015
Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder.
    Bipolar disorders, 2008, Volume: 10, Issue:8

    Topics: Adult; Affect; Anticonvulsants; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar

2008
Brain serotonin, psychoactive drugs, and effects on reproduction.
    Central nervous system agents in medicinal chemistry, 2009, Volume: 9, Issue:4

    Topics: Affect; Amphetamine-Related Disorders; Animals; Biological Clocks; Brain; Cognition Disorders; Depre

2009
Three cases of zolpidem dependence treated with fluoxetine: the serotonin hypothesis.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2003, Volume: 4, Issue:2

    Topics: Adult; Female; Fluoxetine; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Pyridines; Selectiv

2003
Long-term treatment of an addictive personality.
    Bulletin of the Menninger Clinic, 2003,Fall, Volume: 67, Issue:4

    Topics: Adult; Antidepressive Agents, Second-Generation; Behavior, Addictive; Depressive Disorder; Diagnosis

2003
Oral transmucosal abuse of transdermal fentanyl.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Chronic Disease; Depressive Disorder; Drug A

2004
A fatal overdose of cocaine associated with coingestion of marijuana, buprenorphine, and fluoxetine. Body fluid and tissue distribution of cocaine and its metabolites determined by hydrophilic interaction chromatography-mass spectrometry(HILIC-MS).
    Journal of analytical toxicology, 2004, Volume: 28, Issue:6

    Topics: Analgesics, Opioid; Biotransformation; Buprenorphine; Cannabinoids; Chromatography, Liquid; Cocaine;

2004
Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:3

    Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aggression; Animals; Anti-Anxiety Age

2008
Behavioral economic analysis of drug preference using multiple choice procedure data.
    Drug and alcohol dependence, 2008, Jan-11, Volume: 93, Issue:1-2

    Topics: Choice Behavior; Economics; Fentanyl; Fluoxetine; Hallucinogens; Humans; Hydromorphone; Injections,

2008
A case of unexpected and selective remission of a 20-year history of ephedrine dependence following treatment with low-dose aripiprazole.
    The Journal of clinical psychiatry, 2007, Volume: 68, Issue:10

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Depressive Disorder, Major; Drug Administration Schedule;

2007
The effects of putative 5-hydroxytryptamine receptor active agents on D-amphetamine self-administration in controls and rats with 5,7-dihydroxytryptamine median forebrain bundle lesions.
    Brain research, 1984, Jun-11, Volume: 303, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Cyproheptadine; Dextroamphetamine; Fluoxetine; Humans; Male; Media

1984
Treatment of coexisting substance dependence and posttramatic stress disorder.
    Psychiatric services (Washington, D.C.), 1995, Volume: 46, Issue:7

    Topics: Adult; Alcoholism; Behavior Therapy; Combined Modality Therapy; Comorbidity; Fluoxetine; Humans; Ill

1995
Fluoxetine treatment for dually diagnosed methadone maintained opioid addicts: a pilot study.
    Journal of addictive diseases, 1994, Volume: 13, Issue:3

    Topics: Adult; Cocaine; Combined Modality Therapy; Comorbidity; Depressive Disorder; Diagnosis, Dual (Psychi

1994
Fluoxetine for cocaine dependence in methadone maintenance.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:5

    Topics: Alcoholism; Cocaine; Dopamine Uptake Inhibitors; Drug Synergism; Fluoxetine; Heroin Dependence; Huma

1994
[A case of rare side effects of certain antidepressive drugs].
    Der Nervenarzt, 1995, Volume: 66, Issue:1

    Topics: Adult; Antidepressive Agents; Clomipramine; Depressive Disorder; Diagnosis, Differential; Drug Thera

1995
Fluoxetine abuse.
    Mayo Clinic proceedings, 1994, Volume: 69, Issue:2

    Topics: Adult; Female; Fluoxetine; Humans; Male; Substance-Related Disorders

1994
Reinforcing subjective effects of (+/-) 3,4-methylenedioxymethamphetamine ("ecstasy") may be separable from its neurotoxic actions: clinical evidence.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Arousal; Designer Drugs; Dose-Response Relationship, Drug; Dru

1993
Listening to Prozac.
    Nature, 1994, May-19, Volume: 369, Issue:6477

    Topics: Fluoxetine; Humans; Substance-Related Disorders

1994
Listening to Prozac.
    Nature, 1994, May-19, Volume: 369, Issue:6477

    Topics: Fluoxetine; Humans; Substance-Related Disorders

1994
Listening to Prozac.
    Nature, 1994, May-19, Volume: 369, Issue:6477

    Topics: Fluoxetine; Humans; Substance-Related Disorders

1994
SSRI and sympathominetic interaction.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 168, Issue:2

    Topics: Adult; Amphetamine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Flu

1996
Fluoxetine addition to methadone in addicts: pharmacokinetic aspects.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:5

    Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Drug Interactions; Female; Fluo

1996
Drug craving and other negative reactions after abrupt substitution of nefazodone for other serotonergic agents.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:10

    Topics: Antidepressive Agents, Second-Generation; Cyclohexanols; Drug Administration Schedule; Female; Fluox

1996
Changes in serotonin and norepinephrine uptake sites after chronic cocaine: pre- vs. post-withdrawal effects.
    Brain research, 1996, Oct-14, Volume: 736, Issue:1-2

    Topics: Administration, Oral; Animals; Autoradiography; Biological Transport; Brain; Carrier Proteins; Cocai

1996
Fluoxetine abuse.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Fluoxetine; Humans; Substance-Related Disorders

1996
[For some it is a matter of necessity. Worry about the overuse of an antidepressant].
    Nordisk medicin, 1998, Volume: 113, Issue:6

    Topics: Depression; Dose-Response Relationship, Drug; Fluoxetine; Humans; Selective Serotonin Reuptake Inhib

1998
Loss of anxiety and increased aggression in a 15-year-old boy taking fluoxetine.
    Journal of psychopharmacology (Oxford, England), 1999, Volume: 13, Issue:4

    Topics: Adolescent; Aggression; Antidepressive Agents, Second-Generation; Anxiety; Fluoxetine; Humans; Male;

1999
Ethics, humility, and psychotropic medications.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84, Issue:9

    Topics: Adult; Attitude of Health Personnel; Dose-Response Relationship, Drug; Ethics, Medical; Female; Fluo

2001
The use of fluoxetine in depression associated with anabolic steroid withdrawal: a case series.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:4

    Topics: Adult; Anabolic Agents; Depressive Disorder; Fluoxetine; Humans; Male; Substance Withdrawal Syndrome

1992
Potential interaction of LSD and fluoxetine.
    The American journal of psychiatry, 1992, Volume: 149, Issue:6

    Topics: Adolescent; Drug Interactions; Epilepsy, Tonic-Clonic; Fluoxetine; Humans; Lysergic Acid Diethylamid

1992
Current status of tricyclic antidepressants in psychiatry: their pharmacology and clinical applications.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:4

    Topics: Aged; Antidepressive Agents, Tricyclic; Anxiety Disorders; Cocaine; Depressive Disorder; Feeding and

1991
Fluoxetine for cocaine abuse in methadone patients: preliminary findings.
    NIDA research monograph, 1990, Volume: 105

    Topics: Adult; Cocaine; Female; Fluoxetine; Heroin Dependence; Humans; Male; Methadone; Substance-Related Di

1990
Hypomania with fluoxetine.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:5

    Topics: Adjustment Disorders; Bipolar Disorder; Child; Fluoxetine; Humans; Male; Substance-Related Disorders

1991
Fluoxetine treatment of cocaine abuse in heroin addicts.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:1

    Topics: Adult; Cocaine; Female; Fluoxetine; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; S

1991
Ritualistic use of fluoxetine by a former substance abuser.
    The American journal of psychiatry, 1990, Volume: 147, Issue:10

    Topics: Adult; Depressive Disorder; Female; Fluoxetine; Humans; Self Administration; Substance-Related Disor

1990
Fluoxetine-induced attenuation of amphetamine self-administration in rats.
    Life sciences, 1986, Oct-13, Volume: 39, Issue:15

    Topics: Amphetamines; Animals; Brain Chemistry; Fluoxetine; Male; Neurons; Propylamines; Rats; Rats, Inbred

1986
Abuse of fluoxetine by a patient with anorexia nervosa.
    The American journal of psychiatry, 1987, Volume: 144, Issue:8

    Topics: Adult; Anorexia Nervosa; Body Weight; Depressive Disorder; Female; Fluoxetine; Humans; Propylamines;

1987
Safety of fluoxetine in the treatment of obesity.
    International journal of obesity, 1987, Volume: 11 Suppl 3

    Topics: Drug Interactions; Fluoxetine; Heart; Humans; Lipidoses; Liver; Obesity; Phospholipids; Propylamines

1987