fluoxetine has been researched along with Chagas Disease in 2 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "cruzi-induced depression is independent of active or prior CNS inflammation." | 1.38 | Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions. ( de Almeida, LR; de Souza, AS; Lannes-Vieira, J; Moreira, OC; Pereira, IR; Rocha, MS; Silva, AA; Silva, RR; Vilar-Pereira, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Engel, JC | 1 |
| Ang, KK | 1 |
| Chen, S | 1 |
| Arkin, MR | 1 |
| McKerrow, JH | 1 |
| Doyle, PS | 1 |
| Vilar-Pereira, G | 1 |
| Silva, AA | 1 |
| Pereira, IR | 1 |
| Silva, RR | 1 |
| Moreira, OC | 1 |
| de Almeida, LR | 1 |
| de Souza, AS | 1 |
| Rocha, MS | 1 |
| Lannes-Vieira, J | 1 |
2 other studies available for fluoxetine and Chagas Disease
| Article | Year |
|---|---|
Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Chagas Disease; Drug Evaluation, Preclinical; Hepatocy | 2010 |
Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions.
Topics: Animals; Antidepressive Agents, Second-Generation; Chagas Disease; Depression; Emotions; Exploratory | 2012 |