fluoxetine has been researched along with Cerebrovascular Disorders in 18 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| ", 1994) we systematically collected data from 219 patients with Major Depressive Disorder during five weeks of treatment with fluoxetine (20 mg daily)." | 5.08 | Drug monitoring studies as a method of analyzing response criteria. ( Klieser, E; Lehmann, E, 1997) |
| " This paper reports the effect of fluoxetine in treating three patients with persistent emotionalism (2 cases following cerebrovascular accidents, 1 case following encephalitis)." | 3.70 | Treatment of emotionalism with fluoxetine during rehabilitation. ( Lai, JS; Tsai, WC; Wang, TG, 1998) |
| "The clinical picture is one of melancholia in 5 to 25% of cases, and of minor or masked depression (with psychomotor retardation and somatic disorders predominating) in 75 to 95% of cases." | 2.40 | [Post-cerebrovascular stroke depression]. ( Wiart, L, 1997) |
| "Depressive disorder is a common complication of stroke." | 2.38 | Depression and cerebrovascular disease. ( Fedoroff, JP; Morris, PL; Robinson, RG, 1990) |
| "Serotonin syndrome is the result of the drug interaction that enhances serotonergic tone in the central nervous system." | 1.30 | Serotonin syndrome presenting with migrainelike stroke. ( Molaie, M, 1997) |
| "Fluoxetine was associated temporally with frequent short episodes of sexual excitement described by the patient as feeling like an orgasm." | 1.28 | Fluoxetine and orgasmic sexual experiences. ( Morris, PL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (88.89) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, P | 1 |
| Zhang, X | 1 |
| Lu, Y | 1 |
| Chen, C | 1 |
| Li, C | 1 |
| Zhou, M | 1 |
| Lu, Q | 1 |
| Xu, X | 1 |
| Shen, G | 1 |
| Guo, L | 1 |
| Taragano, FE | 1 |
| Bagnatti, P | 1 |
| Allegri, RF | 1 |
| Hanger, HC | 1 |
| Weinman, E | 1 |
| Ruskin, PE | 1 |
| Berthier, ML | 2 |
| Kulisevsky, J | 2 |
| Stamenkovic, M | 1 |
| Schindler, S | 1 |
| Kasper, S | 1 |
| Dam, M | 1 |
| Tonin, P | 1 |
| De Boni, A | 1 |
| Pizzolato, G | 1 |
| Casson, S | 1 |
| Ermani, M | 1 |
| Freo, U | 1 |
| Piron, L | 1 |
| Battistin, L | 1 |
| Boyeson, MG | 1 |
| Liu, CY | 1 |
| Yang, YY | 1 |
| Wang, SJ | 1 |
| Fuh, JL | 1 |
| Liu, HC | 1 |
| Lehmann, E | 1 |
| Klieser, E | 1 |
| Molaie, M | 1 |
| Wiart, L | 1 |
| Tsai, WC | 1 |
| Lai, JS | 1 |
| Wang, TG | 1 |
| Robinson, RG | 2 |
| Nahas, Z | 1 |
| Arlinghaus, KA | 1 |
| Kotrla, KJ | 1 |
| Clearman, RR | 1 |
| George, MS | 1 |
| Morris, PL | 2 |
| Fedoroff, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Depression Occurring in the Setting of Cerebrovascular Risk -- A Pilot Study[NCT00781326] | Phase 4 | 9 participants (Actual) | Interventional | 2008-08-31 | Terminated (stopped due to Final cost of study medication was significantly greater than initial estimate,) | ||
| Effects of 3 Months Daily Treatment With Selective Serotonin Reuptake Inhibitor (SSRI, Fluoxetine) on Motor Rehabilitation After Ischemic Stroke. FLAME Trial[NCT00657163] | Phase 2 | 100 participants (Anticipated) | Interventional | 2005-03-31 | Completed | ||
| Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction[NCT02386475] | Phase 4 | 39 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Cortex Motor Function Reorganization in Stroke Patients: A Longitudinal fMRI Study[NCT04794673] | 36 participants (Actual) | Observational | 2020-01-12 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Hamilton Depression Rating Scale (24 item) measures symptoms of major depression. We report total score which is the sum of all items. Total score range is 0 to 76 with higher scores indicating more severe depression. We reports scores at end of Phase I for subjects completing the phase. (NCT00781326)
Timeframe: End of Phase I (at 24 weeks)
| Intervention | units on a scale (Mean) |
|---|---|
| Open Label Antidepressant | 9.5 |
3 reviews available for fluoxetine and Cerebrovascular Disorders
| Article | Year |
|---|---|
[Post-cerebrovascular stroke depression].
Topics: Antidepressive Agents; Cerebrovascular Disorders; Combined Modality Therapy; Depressive Disorder; El | 1997 |
Treatment issues in poststroke depression.
Topics: Activities of Daily Living; Antidepressive Agents; Cerebrovascular Disorders; Cognition Disorders; D | 1998 |
Depression and cerebrovascular disease.
Topics: Cerebrovascular Disorders; Depressive Disorder; Desipramine; Female; Fluoxetine; Humans; Male; Nortr | 1990 |
4 trials available for fluoxetine and Cerebrovascular Disorders
| Article | Year |
|---|---|
A double-blind, randomized clinical trial to assess the augmentation with nimodipine of antidepressant therapy in the treatment of "vascular depression".
Topics: Aged; Antidepressive Agents, Second-Generation; Argentina; Calcium Channel Blockers; Cerebrovascular | 2005 |
Poststroke depression and fluoxetine.
Topics: Cerebrovascular Disorders; Depressive Disorder; Fluoxetine; Humans; Treatment Outcome | 1996 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera | 1996 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera | 1996 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera | 1996 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera | 1996 |
Drug monitoring studies as a method of analyzing response criteria.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; Depres | 1997 |
11 other studies available for fluoxetine and Cerebrovascular Disorders
| Article | Year |
|---|---|
Fluoxetine ameliorates cognitive impairments induced by chronic cerebral hypoperfusion via down-regulation of HCN2 surface expression in the hippocampal CA1 area in rats.
Topics: Animals; CA1 Region, Hippocampal; Carotid Stenosis; Cerebrovascular Circulation; Cerebrovascular Dis | 2016 |
Emotionalism after stroke.
Topics: Affective Symptoms; Aged; Cerebrovascular Disorders; Crying; Fluoxetine; Humans; Male | 1993 |
Anger attacks in poststroke depression: response to fluoxetine.
Topics: Anger; Cerebrovascular Disorders; Depressive Disorder; Fluoxetine; Humans; Male; Middle Aged | 1994 |
Fluoxetine--induced mania in a patient with post-stroke depression.
Topics: Bipolar Disorder; Cerebrovascular Disorders; Depressive Disorder; Female; Fluoxetine; Humans; Middle | 1993 |
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; C | 1996 |
Fluoxetine-related suicidality and muscle aches in a patient with poststroke depression.
Topics: Aged; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; Depressive Disorder; Fluo | 1996 |
A new case of fluoxetine-induced mania in poststroke depression.
Topics: Adult; Antidepressive Agents, Second-Generation; Bipolar Disorder; Cerebrovascular Disorders; Depres | 1997 |
Serotonin syndrome presenting with migrainelike stroke.
Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Clomipramine; Confusi | 1997 |
Treatment of emotionalism with fluoxetine during rehabilitation.
Topics: Affective Symptoms; Aged; Antidepressive Agents, Second-Generation; Cerebrovascular Disorders; Encep | 1998 |
Rapid response of emotional incontinence to selective serotonin reuptake inhibitors.
Topics: Adult; Affective Symptoms; Aged; Brain Injuries; Cerebrovascular Disorders; Crying; Fluoxetine; Huma | 1998 |
Fluoxetine and orgasmic sexual experiences.
Topics: Aged; Cerebrovascular Disorders; Depressive Disorder; Fluoxetine; Humans; Male; Orgasm; Sexual Behav | 1991 |