Page last updated: 2024-10-27

fluoxetine and Cerebral Ischemia

fluoxetine has been researched along with Cerebral Ischemia in 25 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
" This trial compared the functional outcomes of subjects poststroke receiving fluoxetine versus placebo."9.41Does the Initiation of Fluoxetine Postacute Stroke Result in Improved Functional Recovery?: A Critically Appraised Topic. ( Alcott, SB; Demaerschalk, BM; Knox, MG; Marks, LA; O'Carroll, CB; Wingerchuk, DM, 2021)
"To determine if fluoxetine 20 mg by mouth daily, given within 14 days of acute ischemic stroke, and taken for 90 days, is well-tolerated and safe with adequate adherence to justify a future randomized, controlled trial of fluoxetine in the United Republic of Tanzania."9.34MAMBO: Measuring ambulation, motor, and behavioral outcomes with post-stroke fluoxetine in Tanzania: Protocol of a phase II clinical trial. ( Buma, D; Chiwanga, F; Ismail, SS; Mateen, FJ; Okeng'o, K; Pothier, L; Vogel, AC, 2020)
"To evaluate the effect of fluoxetine on three-year recurrence rate of acute ischemic stroke."9.27Effect of fluoxetine on three-year recurrence in acute ischemic stroke: A randomized controlled clinical study. ( Cai, Z; Chang, X; Chen, S; Guo, Y; He, Y; Liang, Y; Tang, B; Zeng, S, 2018)
"We investigated the effects of fluoxetine on the short-term and long-term neural functional prognoses after ischemic stroke."9.22Effects of Fluoxetine on Neural Functional Prognosis after Ischemic Stroke: A Randomized Controlled Study in China. ( Cai, ZL; Guo, Y; He, YT; Jiang, X; Tang, BS; Zeng, SL, 2016)
"To evaluate the effect of using fluoxetine at different time intervals after ischemic stroke on neurological functional prognosis in China."9.22Effect of using fluoxetine at different time windows on neurological functional prognosis after ischemic stroke. ( Cai, Z; Guo, Y; He, Y; Jiang, X; Ma, K; Tang, B; Zeng, S; Zhang, Y, 2016)
"Our study aimed to evaluate the effect of fluoxetine on morning blood pressure surge (MBPS) in patients with ischemic stroke."8.02The effect of fluoxetine on morning blood pressure surge in patients with ischemic stroke: a prospective preliminary clinical study. ( Cai, Z; Deng, J; Guo, Y; He, Y; Zhang, H; Zhang, Y, 2021)
"Three large trials of fluoxetine for stroke recovery (FOCUS (fluoxetine or control under supervision), AFFINITY (the Assessment oF FluoxetINe In sTroke recovery) and EFFECTS (Efficacy oF Fluoxetine-a randomisEd Controlled Trial in Stroke)) have been collaboratively designed with the same basic protocol to facilitate an individual patient data analysis (IPDM)."7.96Update to the FOCUS, AFFINITY and EFFECTS trials studying the effect(s) of fluoxetine in patients with a recent stroke: statistical analysis plan for the trials and for the individual patient data meta-analysis. ( Billot, L; Dennis, M; Forbes, J; Graham, C; Hackett, ML; Hankey, GJ; Lewis, S; Lundström, E; Mead, GE; Näsman, P, 2020)
"The serotonin selective reuptake inhibitor fluoxetine (Flx) has tried to treat patients suffered acute ischemic stroke because of its possible neuroprotective actions."7.78Optimal dosages of fluoxetine in the treatment of hypoxic brain injury induced by 3-nitropropionic acid: implications for the adjunctive treatment of patients after acute ischemic stroke. ( Sun, Y; Sun, ZQ; Yang, G; Zhou, CH; Zhu, BG; Zhu, RS, 2012)
"Fluoxetine treatment reduced the infarct size of rats after cerebral ischemia reperfusion injury."5.51Fluoxetine mitigating late-stage cognition and neurobehavior impairment induced by cerebral ischemia reperfusion injury through inhibiting ERS-mediated neurons apoptosis in the hippocampus. ( Ge, MY; Li, Y; Peng, L; Wang, S; Xu, F; Yin, J; Zhang, G; Zhang, Q, 2019)
" This trial compared the functional outcomes of subjects poststroke receiving fluoxetine versus placebo."5.41Does the Initiation of Fluoxetine Postacute Stroke Result in Improved Functional Recovery?: A Critically Appraised Topic. ( Alcott, SB; Demaerschalk, BM; Knox, MG; Marks, LA; O'Carroll, CB; Wingerchuk, DM, 2021)
"To determine if fluoxetine 20 mg by mouth daily, given within 14 days of acute ischemic stroke, and taken for 90 days, is well-tolerated and safe with adequate adherence to justify a future randomized, controlled trial of fluoxetine in the United Republic of Tanzania."5.34MAMBO: Measuring ambulation, motor, and behavioral outcomes with post-stroke fluoxetine in Tanzania: Protocol of a phase II clinical trial. ( Buma, D; Chiwanga, F; Ismail, SS; Mateen, FJ; Okeng'o, K; Pothier, L; Vogel, AC, 2020)
"To evaluate the effect of fluoxetine on three-year recurrence rate of acute ischemic stroke."5.27Effect of fluoxetine on three-year recurrence in acute ischemic stroke: A randomized controlled clinical study. ( Cai, Z; Chang, X; Chen, S; Guo, Y; He, Y; Liang, Y; Tang, B; Zeng, S, 2018)
"We investigated the effects of fluoxetine on the short-term and long-term neural functional prognoses after ischemic stroke."5.22Effects of Fluoxetine on Neural Functional Prognosis after Ischemic Stroke: A Randomized Controlled Study in China. ( Cai, ZL; Guo, Y; He, YT; Jiang, X; Tang, BS; Zeng, SL, 2016)
"To evaluate the effect of using fluoxetine at different time intervals after ischemic stroke on neurological functional prognosis in China."5.22Effect of using fluoxetine at different time windows on neurological functional prognosis after ischemic stroke. ( Cai, Z; Guo, Y; He, Y; Jiang, X; Ma, K; Tang, B; Zeng, S; Zhang, Y, 2016)
"Our study aimed to evaluate the effect of fluoxetine on morning blood pressure surge (MBPS) in patients with ischemic stroke."4.02The effect of fluoxetine on morning blood pressure surge in patients with ischemic stroke: a prospective preliminary clinical study. ( Cai, Z; Deng, J; Guo, Y; He, Y; Zhang, H; Zhang, Y, 2021)
"Three large trials of fluoxetine for stroke recovery (FOCUS (fluoxetine or control under supervision), AFFINITY (the Assessment oF FluoxetINe In sTroke recovery) and EFFECTS (Efficacy oF Fluoxetine-a randomisEd Controlled Trial in Stroke)) have been collaboratively designed with the same basic protocol to facilitate an individual patient data analysis (IPDM)."3.96Update to the FOCUS, AFFINITY and EFFECTS trials studying the effect(s) of fluoxetine in patients with a recent stroke: statistical analysis plan for the trials and for the individual patient data meta-analysis. ( Billot, L; Dennis, M; Forbes, J; Graham, C; Hackett, ML; Hankey, GJ; Lewis, S; Lundström, E; Mead, GE; Näsman, P, 2020)
"Fluoxetine, a selective serotonin reuptake inhibitor, exerts neuroprotective effects in a variety of neurological diseases including stroke, but the underlying mechanism remains obscure."3.83Fluoxetine protects against IL-1β-induced neuronal apoptosis via downregulation of p53. ( Bian, Y; Ding, J; Hu, G; Lu, M; Shan, H; Shu, Z; Xiao, M; Zhang, L; Zhu, J, 2016)
"The serotonin selective reuptake inhibitor fluoxetine (Flx) has tried to treat patients suffered acute ischemic stroke because of its possible neuroprotective actions."3.78Optimal dosages of fluoxetine in the treatment of hypoxic brain injury induced by 3-nitropropionic acid: implications for the adjunctive treatment of patients after acute ischemic stroke. ( Sun, Y; Sun, ZQ; Yang, G; Zhou, CH; Zhu, BG; Zhu, RS, 2012)
" The aim of this study was to investigate the effects of the SSRIs citalopram and fluoxetine, on the corticocerebral blood flow (cCBF) in rabbits with unilateral carotid occlusion induced cerebral ischemia."3.74Effects of citalopram and fluoxetine on the corticocerebral blood flow in conscious rabbits. ( Csete, K; Papp, JG; Sas, K; Sztriha, L; Vécseil, L; Vezekényi, Z, 2007)
"Fluoxetine treatment reduced the infarct size of rats after cerebral ischemia reperfusion injury."1.51Fluoxetine mitigating late-stage cognition and neurobehavior impairment induced by cerebral ischemia reperfusion injury through inhibiting ERS-mediated neurons apoptosis in the hippocampus. ( Ge, MY; Li, Y; Peng, L; Wang, S; Xu, F; Yin, J; Zhang, G; Zhang, Q, 2019)
"Fluoxetine treatment (10 mg/kg) after global ischemia significantly inhibited mRNA expression of MMP-2 and -9 and reduced MMP-9 activity."1.40Fluoxetine inhibits transient global ischemia-induced hippocampal neuronal death and memory impairment by preventing blood-brain barrier disruption. ( Choi, HY; Kang, SR; Lee, HE; Lee, JY; Ryu, JH; Yune, TY, 2014)
"Fluoxetine has been given to stroke patients to combat depression but its effects on recovery of function are not known."1.33Fluoxetine and recovery of motor function after focal ischemia in rats. ( Corbett, D; Windle, V, 2005)
"Serotonin syndrome is the result of the drug interaction that enhances serotonergic tone in the central nervous system."1.30Serotonin syndrome presenting with migrainelike stroke. ( Molaie, M, 1997)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.00)18.2507
2000's3 (12.00)29.6817
2010's16 (64.00)24.3611
2020's4 (16.00)2.80

Authors

AuthorsStudies
Vogel, AC1
Okeng'o, K1
Chiwanga, F1
Ismail, SS1
Buma, D1
Pothier, L1
Mateen, FJ1
Mead, GE1
Graham, C1
Billot, L1
Näsman, P1
Lundström, E1
Lewis, S1
Hankey, GJ1
Hackett, ML1
Forbes, J1
Dennis, M1
He, Y3
Deng, J1
Zhang, Y2
Cai, Z3
Zhang, H1
Guo, Y4
Knox, MG1
Demaerschalk, BM1
Alcott, SB1
Marks, LA1
Wingerchuk, DM1
O'Carroll, CB1
Zeng, S2
Chen, S1
Tang, B2
Liang, Y1
Chang, X1
Xu, F1
Zhang, G1
Yin, J1
Zhang, Q1
Ge, MY1
Peng, L1
Wang, S1
Li, Y1
Hua, Y1
Li, C1
Hu, J1
Wang, YY1
Liu, PL1
Gao, BY1
Chen, C1
Xu, DS1
Zhang, B1
Bai, YL1
Dhami, KS1
Churchward, MA1
Baker, GB1
Todd, KG1
Lee, JY1
Lee, HE1
Kang, SR1
Choi, HY1
Ryu, JH1
Yune, TY1
Corbett, AM1
Sieber, S1
Wyatt, N1
Lizzi, J1
Flannery, T1
Sibbit, B1
Sanghvi, S1
Schambra, H1
Im, B1
O'Dell, MW1
He, YT1
Tang, BS1
Cai, ZL1
Zeng, SL1
Jiang, X2
Ma, K1
Shan, H1
Bian, Y1
Shu, Z1
Zhang, L1
Zhu, J1
Ding, J1
Lu, M1
Xiao, M1
Hu, G1
Sas, K2
Gaillard, R1
Mir, O1
Gonzenbach, RR1
Taegtmeyer, AB1
Luft, A1
Russmann, S1
Taguchi, N1
Nakayama, S1
Tanaka, M1
Zhu, BG1
Sun, Y1
Sun, ZQ1
Yang, G1
Zhou, CH1
Zhu, RS1
Ohira, K1
Takeuchi, R1
Shoji, H1
Miyakawa, T1
Zhao, CS1
Puurunen, K1
Schallert, T1
Sivenius, J1
Jolkkonen, J1
Windle, V1
Corbett, D1
Csete, K1
Vezekényi, Z1
Sztriha, L1
Vécseil, L1
Papp, JG1
Dam, M1
Tonin, P1
De Boni, A1
Pizzolato, G1
Casson, S1
Ermani, M1
Freo, U1
Piron, L1
Battistin, L1
Molaie, M1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
MAMBO: Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania[NCT03728153]Phase 234 participants (Actual)Interventional2019-11-26Completed
Establishing the Effect(s) and Safety of Fluoxetine Initiated in the Acute Phase of Stroke[NCT02683213]Phase 31,500 participants (Actual)Interventional2014-10-20Completed
FLOW Trial: Fluoxetine to Open the Critical Period Time Window to Improve Motor Recovery After Stroke[NCT03448159]Phase 252 participants (Actual)Interventional2019-01-01Completed
Effects of 3 Months Daily Treatment With Selective Serotonin Reuptake Inhibitor (SSRI, Fluoxetine) on Motor Rehabilitation After Ischemic Stroke. FLAME Trial[NCT00657163]Phase 2100 participants (Anticipated)Interventional2005-03-31Completed
Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction[NCT02386475]Phase 439 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Fugl-Meyer Motor Scale Score for Assessment of Motor Function After Stroke

The Fugl Meyer motor scale is used to assess post-stroke motor recovery in stroke patients. It is scored on a scale from 0 to 100, with lower scores indicating greater disability. It evaluates both lower and upper extremities for motor performance: 66 points are allocated to the upper extremities, 34 to the lower extremities. The two extremities are summed to achieve the total score. (NCT03728153)
Timeframe: 90 days following acute, ischemic stroke

Interventionscore on a scale (Mean)
20mg Dose62.7

Modified Rankin Scale

Validated instrument for measuring the degree of disability in stroke patients. The modified Rankin Scale is based on a physicians subjective evaluation. The scale ranges from 0, indicating perfect health, to 6, indicating that the patient is dead. (NCT03728153)
Timeframe: 90 days following acute, ischemic stroke

Interventionscore on a scale (Median)
20mg Dose2

Montgomery-Asberg Depression Rating Scale

10-item questionnaire used to evaluate the severity of a patient's depressive symptoms. Each item is scored on a scale from 0 to 6, the scores are summed, and the total score (0 to 60 points) is reported. The greater the score, the more severe the degree of depression. (NCT03728153)
Timeframe: 90 days following acute, ischemic stroke

Interventionunits on a scale (Mean)
20mg Dose5.6

Serum Alanine Aminotransferase (ALT)

Hepatic impairment was measured by elevation of hepatic enzyme (serum alanine aminotransferase; ALT) of >120 U/L (NCT03728153)
Timeframe: 90 days

InterventionU/L (Mean)
20mg Dose28

Serum Sodium Concentration

Serum Sodium Concentration was measured in mmol/L. Hyponatremia was considered as <125 mmol/L. (NCT03728153)
Timeframe: 90 days following acute, ischemic stroke

Interventionmmol/L (Mean)
20mg Dose138.7

The Patient Health Questionnaire-9 (PHQ-9) Scale for Measuring Depression

The PHQ-9 is a validated 9-point questionnaire for measuring depression symptom severity. Each question is scored from 0-3. Answers are summed and the total score (0 to 27) is reported. The greater the score, the greater the severity of depression. (NCT03728153)
Timeframe: 90 days following acute ischemic stroke

Interventionunits on a scale (Mean)
20mg Dose4.6

Reviews

1 review available for fluoxetine and Cerebral Ischemia

ArticleYear
Should This Patient With Ischemic Stroke Receive Fluoxetine?
    PM & R : the journal of injury, function, and rehabilitation, 2015, Volume: 7, Issue:12

    Topics: Aged; Brain Ischemia; Decision Making; Disability Evaluation; Fluoxetine; Humans; Male; Selective Se

2015

Trials

7 trials available for fluoxetine and Cerebral Ischemia

ArticleYear
MAMBO: Measuring ambulation, motor, and behavioral outcomes with post-stroke fluoxetine in Tanzania: Protocol of a phase II clinical trial.
    Journal of the neurological sciences, 2020, Jan-15, Volume: 408

    Topics: Brain Ischemia; Female; Fluoxetine; Humans; Male; Motor Activity; Recovery of Function; Selective Se

2020
Does the Initiation of Fluoxetine Postacute Stroke Result in Improved Functional Recovery?: A Critically Appraised Topic.
    The neurologist, 2021, May-05, Volume: 26, Issue:3

    Topics: Brain Ischemia; Fluoxetine; Humans; Recovery of Function; Selective Serotonin Reuptake Inhibitors; S

2021
Effect of fluoxetine on three-year recurrence in acute ischemic stroke: A randomized controlled clinical study.
    Clinical neurology and neurosurgery, 2018, Volume: 168

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Brain Ischemia; Female; Fluoxetine; Foll

2018
Effects of Fluoxetine on Neural Functional Prognosis after Ischemic Stroke: A Randomized Controlled Study in China.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2016, Volume: 25, Issue:4

    Topics: Brain Ischemia; China; Female; Fluoxetine; Follow-Up Studies; Humans; Male; Prognosis; Selective Ser

2016
Effect of using fluoxetine at different time windows on neurological functional prognosis after ischemic stroke.
    Restorative neurology and neuroscience, 2016, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Brain Ischemia; China; Double-Blind Meth

2016
Fluoxetine has neuroprotective effects after cardiac arrest and cardiopulmonary resuscitation in mouse.
    Resuscitation, 2012, Volume: 83, Issue:5

    Topics: Animals; Brain; Brain Ischemia; Cardiopulmonary Resuscitation; Fluoxetine; Heart Arrest; Male; Mice;

2012
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera

1996
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera

1996
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera

1996
Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.
    Stroke, 1996, Volume: 27, Issue:7

    Topics: Activities of Daily Living; Adrenergic Uptake Inhibitors; Aged; Antidepressive Agents, Second-Genera

1996

Other Studies

17 other studies available for fluoxetine and Cerebral Ischemia

ArticleYear
Update to the FOCUS, AFFINITY and EFFECTS trials studying the effect(s) of fluoxetine in patients with a recent stroke: statistical analysis plan for the trials and for the individual patient data meta-analysis.
    Trials, 2020, Nov-25, Volume: 21, Issue:1

    Topics: Aged; Brain Ischemia; Data Interpretation, Statistical; Female; Fluoxetine; Humans; Male; Meta-Analy

2020
The effect of fluoxetine on morning blood pressure surge in patients with ischemic stroke: a prospective preliminary clinical study.
    Blood pressure monitoring, 2021, Aug-01, Volume: 26, Issue:4

    Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brain Ischemia; Circadian Rhythm; Fluoxetine;

2021
Fluoxetine mitigating late-stage cognition and neurobehavior impairment induced by cerebral ischemia reperfusion injury through inhibiting ERS-mediated neurons apoptosis in the hippocampus.
    Behavioural brain research, 2019, 09-16, Volume: 370

    Topics: Animals; Apoptosis; Brain Ischemia; Cognition; Endoplasmic Reticulum Stress; Fluoxetine; Hippocampus

2019
Fluoxetine adjunct to therapeutic exercise promotes motor recovery in rats with cerebral ischemia: Roles of nucleus accumbens.
    Brain research bulletin, 2019, Volume: 153

    Topics: Animals; Brain Ischemia; Exercise Therapy; Fluoxetine; Infarction, Middle Cerebral Artery; Male; Mot

2019
Fluoxetine and citalopram decrease microglial release of glutamate and D-serine to promote cortical neuronal viability following ischemic insult.
    Molecular and cellular neurosciences, 2013, Volume: 56

    Topics: Animals; Brain Ischemia; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Citalopram;

2013
Fluoxetine inhibits transient global ischemia-induced hippocampal neuronal death and memory impairment by preventing blood-brain barrier disruption.
    Neuropharmacology, 2014, Volume: 79

    Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Ischemia; Capillary Permeability; Cell Death; Fluoxe

2014
Increasing neurogenesis with fluoxetine, simvastatin and ascorbic Acid leads to functional recovery in ischemic stroke.
    Recent patents on drug delivery & formulation, 2015, Volume: 9, Issue:2

    Topics: Animals; Ascorbic Acid; Brain; Brain Ischemia; Drug Therapy, Combination; Female; Fluoxetine; Male;

2015
Fluoxetine protects against IL-1β-induced neuronal apoptosis via downregulation of p53.
    Neuropharmacology, 2016, Volume: 107

    Topics: Animals; Anisomycin; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Cell Line, Tumor; Diseas

2016
Potential role of glutamate neurotransmission in the pathogenesis of ischemic brain damage and of depression. Effects of L-kynurenine on the survival of the hippocampal neurons and on the corticocerebral blood flow in ischemic animal models.
    Ideggyogyaszati szemle, 2010, Jan-30, Volume: 63, Issue:1-2

    Topics: Animals; Brain Ischemia; Cell Survival; Cerebrovascular Circulation; Chromatography, High Pressure L

2010
Fluoxetine and motor recovery after ischaemic stroke.
    The Lancet. Neurology, 2011, Volume: 10, Issue:6

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Brain Ischemia; Clopidogrel; Cytochrome P-450 CYP2C19; Drug

2011
Fluoxetine and motor recovery after ischaemic stroke.
    The Lancet. Neurology, 2011, Volume: 10, Issue:6

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Brain Ischemia; Clopidogrel; Cytochrome P-450 CYP2C19; Drug

2011
Optimal dosages of fluoxetine in the treatment of hypoxic brain injury induced by 3-nitropropionic acid: implications for the adjunctive treatment of patients after acute ischemic stroke.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:7

    Topics: Animals; Brain Ischemia; Fluoxetine; Hypoxia, Brain; Male; Mice; Nitro Compounds; Propionates; Rando

2012
Fluoxetine-induced cortical adult neurogenesis.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:6

    Topics: Age Factors; Animals; Brain Ischemia; Cerebral Cortex; Fluoxetine; Interneurons; Male; Mice; Mice, I

2013
Behavioral and histological effects of chronic antipsychotic and antidepressant drug treatment in aged rats with focal ischemic brain injury.
    Behavioural brain research, 2005, Mar-30, Volume: 158, Issue:2

    Topics: Affect; Aggression; Aging; Animals; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; B

2005
Fluoxetine and recovery of motor function after focal ischemia in rats.
    Brain research, 2005, May-17, Volume: 1044, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Infarction; Brain Ischemia; Fluoxetine; Male;

2005
Effects of citalopram and fluoxetine on the corticocerebral blood flow in conscious rabbits.
    Acta physiologica Hungarica, 2007, Volume: 94, Issue:3

    Topics: Animals; Antidepressive Agents, Second-Generation; Blood Pressure; Brain Ischemia; Carotid Arteries;

2007
Serotonin syndrome presenting with migrainelike stroke.
    Headache, 1997, Volume: 37, Issue:8

    Topics: Adult; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Clomipramine; Confusi

1997