fluoxetine has been researched along with Cell Transformation, Neoplastic in 3 studies
Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with fluoxetine attenuated the increased IκB kinase (IKK) and IκBα phosphorylation induced by TNF-α." | 5.37 | Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice. ( Jung, HC; Kim, IK; Kim, JM; Kim, JS; Kim, N; Koh, SJ; Song, IS, 2011) |
| "Pretreatment with fluoxetine attenuated the increased IκB kinase (IKK) and IκBα phosphorylation induced by TNF-α." | 1.37 | Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice. ( Jung, HC; Kim, IK; Kim, JM; Kim, JS; Kim, N; Koh, SJ; Song, IS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saponara, E | 1 |
| Visentin, M | 1 |
| Baschieri, F | 1 |
| Seleznik, G | 1 |
| Martinelli, P | 1 |
| Esposito, I | 1 |
| Buschmann, J | 1 |
| Chen, R | 1 |
| Parrotta, R | 1 |
| Borgeaud, N | 1 |
| Bombardo, M | 1 |
| Malagola, E | 1 |
| Caflisch, A | 1 |
| Farhan, H | 1 |
| Graf, R | 1 |
| Sonda, S | 1 |
| Koh, SJ | 1 |
| Kim, JM | 1 |
| Kim, IK | 1 |
| Kim, N | 1 |
| Jung, HC | 1 |
| Song, IS | 1 |
| Kim, JS | 1 |
| Kannen, V | 1 |
| Hintzsche, H | 1 |
| Zanette, DL | 1 |
| Silva, WA | 1 |
| Garcia, SB | 1 |
| Waaga-Gasser, AM | 1 |
| Stopper, H | 1 |
3 other studies available for fluoxetine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Serotonin uptake is required for Rac1 activation in Kras-induced acinar-to-ductal metaplasia in the pancreas.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Transdifferentiati | 2018 |
Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Fluoxetine; Humans; | 2011 |
Antiproliferative effects of fluoxetine on colon cancer cells and in a colonic carcinogen mouse model.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinogens; Cell Cycle; Cell Proliferation; Cell Trans | 2012 |