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fluoxetine and Carcinoma, Hepatocellular

fluoxetine has been researched along with Carcinoma, Hepatocellular in 5 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine, an antidepressant, has been indicated to elicit anti-cancer response in hepatocellular carcinoma (HCC) and non-small cell lung cancer (NSCLC) in vitro."7.96Beneficial effect of fluoxetine on anti-tumor progression on hepatocellular carcinoma and non-small cell lung cancer bearing animal model. ( Chiang, IT; Hsu, FT; Hsu, LC; Tu, HF; Yueh, PF, 2020)
"The aim of the present study was to verify the effects of fluoxetine on dysregulation of apoptosis and invasive potential in human hepatocellular carcinoma (HCC) SK-Hep1 and Hep3B cells."7.91Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro. ( Chen, CH; Chen, WT; Hsu, FT; Hsu, LC; Lin, SS; Liu, YC, 2019)
" We investigated the apoptotic effect of fluoxetine against the Hep3B human hepatocellular carcinoma cell line."7.79Fluoxetine-induced apoptosis in hepatocellular carcinoma cells. ( Kang, HS; Kim, GB; Kim, JS; Kim, SJ; Lee, SJ; Mun, AR, 2013)
"Fluoxetine, an antidepressant, has been indicated to elicit anti-cancer response in hepatocellular carcinoma (HCC) and non-small cell lung cancer (NSCLC) in vitro."3.96Beneficial effect of fluoxetine on anti-tumor progression on hepatocellular carcinoma and non-small cell lung cancer bearing animal model. ( Chiang, IT; Hsu, FT; Hsu, LC; Tu, HF; Yueh, PF, 2020)
"The aim of the present study was to verify the effects of fluoxetine on dysregulation of apoptosis and invasive potential in human hepatocellular carcinoma (HCC) SK-Hep1 and Hep3B cells."3.91Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro. ( Chen, CH; Chen, WT; Hsu, FT; Hsu, LC; Lin, SS; Liu, YC, 2019)
" We investigated the apoptotic effect of fluoxetine against the Hep3B human hepatocellular carcinoma cell line."3.79Fluoxetine-induced apoptosis in hepatocellular carcinoma cells. ( Kang, HS; Kim, GB; Kim, JS; Kim, SJ; Lee, SJ; Mun, AR, 2013)
"Metastasis of hepatocellular carcinoma (HCC) is usually unrecognized before any pathological examination, resulting in time-taking treatment and poor prognosis."1.48Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells. ( Chen, KC; Hsieh, CL; Maner, RS; Tian, YS; Zulkefli, ND, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Hsu, LC2
Tu, HF1
Hsu, FT2
Yueh, PF1
Chiang, IT1
Tian, YS1
Chen, KC1
Zulkefli, ND1
Maner, RS1
Hsieh, CL1
Chen, WT1
Liu, YC1
Chen, CH1
Lin, SS1
Mun, AR1
Lee, SJ1
Kim, GB1
Kang, HS1
Kim, JS1
Kim, SJ1
Qi, H1
Ma, J1
Liu, YM1
Yang, L1
Peng, L1
Wang, H1
Chen, HZ1

Other Studies

5 other studies available for fluoxetine and Carcinoma, Hepatocellular

ArticleYear
Beneficial effect of fluoxetine on anti-tumor progression on hepatocellular carcinoma and non-small cell lung cancer bearing animal model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 126

    Topics: Adjuvants, Pharmaceutic; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; C

2020
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
    Molecules (Basel, Switzerland), 2018, Dec-14, Volume: 23, Issue:12

    Topics: Carcinoma, Hepatocellular; Fluoxetine; Hep G2 Cells; Humans; Iridoids; Liver Neoplasms; Matrix Metal

2018
Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro.
    International journal of molecular sciences, 2019, Feb-11, Volume: 20, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell P

2019
Fluoxetine-induced apoptosis in hepatocellular carcinoma cells.
    Anticancer research, 2013, Volume: 33, Issue:9

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Fluoxetine; Humans; Liver Neoplasms; Matrix

2013
Allostatic tumor-burden induces depression-associated changes in hepatoma-bearing mice.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic

2009