Page last updated: 2024-10-27

fluoxetine and Cancer of Liver

fluoxetine has been researched along with Cancer of Liver in 7 studies

Fluoxetine: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
fluoxetine : A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder.
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine : An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group.

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated the effects of fluoxetine, desipramine, and mirtazapine on the liver metastasis of murine C26 colon carcinoma (cc)."8.31Stimulatory effect of fluoxetine and desipramine, but not mirtazapine on C26 colon carcinoma hepatic metastases formation: association with cytokines. ( Arteta, B; Curzytek, K; Grygier, B; Kubera, M; Maes, M; Malicki, S, 2023)
"Fluoxetine, an antidepressant, has been indicated to elicit anti-cancer response in hepatocellular carcinoma (HCC) and non-small cell lung cancer (NSCLC) in vitro."7.96Beneficial effect of fluoxetine on anti-tumor progression on hepatocellular carcinoma and non-small cell lung cancer bearing animal model. ( Chiang, IT; Hsu, FT; Hsu, LC; Tu, HF; Yueh, PF, 2020)
"The aim of the present study was to verify the effects of fluoxetine on dysregulation of apoptosis and invasive potential in human hepatocellular carcinoma (HCC) SK-Hep1 and Hep3B cells."7.91Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro. ( Chen, CH; Chen, WT; Hsu, FT; Hsu, LC; Lin, SS; Liu, YC, 2019)
" We investigated the apoptotic effect of fluoxetine against the Hep3B human hepatocellular carcinoma cell line."7.79Fluoxetine-induced apoptosis in hepatocellular carcinoma cells. ( Kang, HS; Kim, GB; Kim, JS; Kim, SJ; Lee, SJ; Mun, AR, 2013)
" In this study, we investigated the effects of fluoxetine, desipramine, and mirtazapine on the liver metastasis of murine C26 colon carcinoma (cc)."4.31Stimulatory effect of fluoxetine and desipramine, but not mirtazapine on C26 colon carcinoma hepatic metastases formation: association with cytokines. ( Arteta, B; Curzytek, K; Grygier, B; Kubera, M; Maes, M; Malicki, S, 2023)
"Fluoxetine, an antidepressant, has been indicated to elicit anti-cancer response in hepatocellular carcinoma (HCC) and non-small cell lung cancer (NSCLC) in vitro."3.96Beneficial effect of fluoxetine on anti-tumor progression on hepatocellular carcinoma and non-small cell lung cancer bearing animal model. ( Chiang, IT; Hsu, FT; Hsu, LC; Tu, HF; Yueh, PF, 2020)
"The aim of the present study was to verify the effects of fluoxetine on dysregulation of apoptosis and invasive potential in human hepatocellular carcinoma (HCC) SK-Hep1 and Hep3B cells."3.91Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro. ( Chen, CH; Chen, WT; Hsu, FT; Hsu, LC; Lin, SS; Liu, YC, 2019)
" We investigated the apoptotic effect of fluoxetine against the Hep3B human hepatocellular carcinoma cell line."3.79Fluoxetine-induced apoptosis in hepatocellular carcinoma cells. ( Kang, HS; Kim, GB; Kim, JS; Kim, SJ; Lee, SJ; Mun, AR, 2013)
"Metastasis of hepatocellular carcinoma (HCC) is usually unrecognized before any pathological examination, resulting in time-taking treatment and poor prognosis."1.48Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells. ( Chen, KC; Hsieh, CL; Maner, RS; Tian, YS; Zulkefli, ND, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Kubera, M1
Arteta, B1
Grygier, B1
Curzytek, K1
Malicki, S1
Maes, M1
Hsu, LC2
Tu, HF1
Hsu, FT2
Yueh, PF1
Chiang, IT1
Tian, YS1
Chen, KC1
Zulkefli, ND1
Maner, RS1
Hsieh, CL1
Chen, WT1
Liu, YC1
Chen, CH1
Lin, SS1
Mun, AR1
Lee, SJ1
Kim, GB1
Kang, HS1
Kim, JS1
Kim, SJ1
Qi, H1
Ma, J1
Liu, YM1
Yang, L1
Peng, L1
Wang, H1
Chen, HZ1
Cai, W1
Khaoustov, VI1
Xie, Q1
Pan, T1
Le, W1
Yoffe, B1

Other Studies

7 other studies available for fluoxetine and Cancer of Liver

ArticleYear
Stimulatory effect of fluoxetine and desipramine, but not mirtazapine on C26 colon carcinoma hepatic metastases formation: association with cytokines.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Antidepressive Agents; Carcinoma; Colonic Neoplasms; Cytokines; Desipramine; Fluoxetine; Li

2023
Beneficial effect of fluoxetine on anti-tumor progression on hepatocellular carcinoma and non-small cell lung cancer bearing animal model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 126

    Topics: Adjuvants, Pharmaceutic; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; C

2020
Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells.
    Molecules (Basel, Switzerland), 2018, Dec-14, Volume: 23, Issue:12

    Topics: Carcinoma, Hepatocellular; Fluoxetine; Hep G2 Cells; Humans; Iridoids; Liver Neoplasms; Matrix Metal

2018
Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro.
    International journal of molecular sciences, 2019, Feb-11, Volume: 20, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell P

2019
Fluoxetine-induced apoptosis in hepatocellular carcinoma cells.
    Anticancer research, 2013, Volume: 33, Issue:9

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Fluoxetine; Humans; Liver Neoplasms; Matrix

2013
Allostatic tumor-burden induces depression-associated changes in hepatoma-bearing mice.
    Journal of neuro-oncology, 2009, Volume: 94, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic

2009
Interferon-alpha-induced modulation of glucocorticoid and serotonin receptors as a mechanism of depression.
    Journal of hepatology, 2005, Volume: 42, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antiviral Agents; Cell C

2005